CAS No. 304456-62-0
Batch:
Purity:98.09
Chemical Structure
Check the
BTYNB
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 2-[(5-bromothiophen-2-yl)methylideneamino]benzamide | |
|---|---|---|
| CAS Number | 304456-62-0 | |
| Molecular Formula |
C12H9BrN2OS |
|
| Molecular Weight (MW) | 309.18 | |
| SMILES | NC(=O)C1=CC=CC=C1N=CC2=CC=C(Br)S2 | |
| InChIKey | OZEADOPONHLEDS-UHFFFAOYSA-N |
BTYNB is a potent and selective inhibitor of IGF2 mRNA-binding protein 1 (IGF2BP1/IMP1) that impairs IMP1 binding to target transcripts, including c-Myc mRNA. By disrupting the IGF2BP1-RNA interaction, BTYNB downregulates β-TrCP1 mRNA levels and attenuates downstream NF-κB signaling, leading to reduced nuclear factor-kappa B activation and suppression of tumor cell proliferation and growth.
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Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
62 mg/mL
(200.53 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 4 mg/mL |
| Water | Insoluble |
| DMSO |
62 mg/mL
(200.53 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 3 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
Note: Technical data last updated: Sep 1, 2026.