CAS No. 52-51-7

Batch: Purity:97
Bronopol Chemical Structure
Chemical Structure
Check the Bronopol product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 52-51-7
Molecular Formula

C3H6BrNO4

Molecular Weight (MW) 199.99
SMILES C(C(CO)([N+](=O)[O-])Br)O

Ordering Information

Biological Activity

Bronopol is an electrophilic broad-spectrum antibacterial agent and preservative that targets bacterial intracellular thiol groups. It oxidizes essential sulfhydryl moieties in microbial proteins and enzymes, leading to the inhibition of key cellular metabolic processes and disruption of cell membrane functionality. These downstream biochemical alterations impair bacterial cell proliferation and induce microbial cell death across Gram-negative and Gram-positive bacterial species.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 39 mg/mL (195.0 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 39 mg/mL
Ethanol 39 mg/mL
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.