CAS No. 734517-40-9
Batch:
Purity:99.78
Chemical Structure
Check the
BRL 15572
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 734517-40-9 | |
|---|---|---|
| Molecular Formula |
C25H27ClN2O |
|
| Molecular Weight (MW) | 406.95 | |
| SMILES | C1CN(CCN1CC(C(C2=CC=CC=C2)C3=CC=CC=C3)O)C4=CC(=CC=C4)Cl |
BRL 15572 is a preferential antagonist of human 5-HT1D receptors that serves as a selective pharmacological tool to distinguish between 5-HT1B and 5-HT1D receptor subtypes. By selectively blocking 5-HT1D receptors, BRL 15572 modulates serotonin-mediated signaling pathways and downstream neural physiological responses. It is widely utilized in functional studies to evaluate serotonin receptor subtype specificity and their distinct roles in neuropharmacology.
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
81 mg/mL
(199.04 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.