CAS No. 67763-87-5

Bleomycin hydrochloride Chemical Structure
Chemical Structure
Check the Bleomycin hydrochloride product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name 3-[[2-[2-[2-[[(2S,3R)-2-[[(2S,3S,4R)-4-[[(2S,3R)-2-[[6-amino-2-[(1S)-3-amino-1-[[(2S)-2,3-diamino-3-oxopropyl]amino]-3-oxopropyl]-5-methylpyrimidine-4-carbonyl]amino]-3-[(2R,3S,4S,5S,6S)-3-[(2R,3S,4S,5R,6R)-4-carbamoyloxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-(1H-imidazol-5-yl)propanoyl]amino]-3-hydroxy-2-methylpentanoyl]amino]-3-hydroxybutanoyl]amino]ethyl]-1,3-thiazol-4-yl]-1,3-thiazole-4-carbonyl]amino]propyl-dimethylsulfanium;hydrochloride
CAS Number 67763-87-5
Molecular Formula
Molecular Weight (MW) 1452.01
InChIKey BODDZCXQPQPRES-OYALTWQYSA-O

Ordering Information

Biological Activity

Bleomycin hydrochloride is a natural glycopeptide antibiotic and DNA synthesis inhibitor. It binds to nuclear DNA and induces single- and double-strand DNA cleavage in a metal-dependent manner, leading to cell cycle arrest in the G2/M phase. Downstream inhibition of DNA replication disrupts cell proliferation and triggers apoptotic cell death, demonstrating potent cytotoxic and antitumor activity against squamous cell carcinoma. [1][2]

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Note: Technical data last updated: Sep 1, 2026.