(-)-Blebbistatin is a potent, selective myosin II ATPase inhibitor. It affects ROCK/MLC and Wnt signaling pathways by blocking actomyosin cross-bridge cycling and reducing cytoskeletal tension, effectively suppressing cell migration, muscle contraction, and viral entry.
(-)-Blebbistatin IC50 for Cell-based and Cell-free Assays
Comprehensive IC50 Values for (-)-Blebbistatin Across Cell-free Enzyme Inhibitory Profiles and Cell-based Functional Assays.