Birinapant is a potent pan-IAP antagonist. It affects NF-κB and apoptotic signaling by promoting cIAP auto-ubiquitylation and degradation, effectively inducing apoptosis and inhibiting tumor cell viability.
Birinapant (TL32711) IC50 for Cell-based and Cell-free Assays
Comprehensive IC50 Values for Birinapant (TL32711) Across Cell-free Enzyme Inhibitory Profiles and Cell-based Functional Assays.