Molecular Weight: 506.59 g/mol
Chemical Structure
Check the
Bireociclib (XZP-3287,CDK4/6-IN-2)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| Ethanol | 100 mg/mL |
| DMSO |
14 mg/mL
(27.63 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Chemical Information
| IUPAC Name | 5-[(4-ethylpiperazin-1-yl)methyl]-N-[5-fluoro-4-(7-fluoro-2-methyl-3-propan-2-ylbenzimidazol-5-yl)-2-pyridinyl]pyrimidin-2-amine | |
|---|---|---|
| CAS Number | 1800506-48-2 | |
| Molecular Formula |
C27H32F2N8 |
|
| Molecular Weight (MW) | 506.59 | |
| SMILES | CCN1CCN(CC2=CN=C(NC3=NC=C(F)C(C4=CC(N(C(C)C)C(C)=N5)=C5C(F)=C4)=C3)N=C2)CC1 | |
| InChIKey | CMOYPFUEZDEQEH-UHFFFAOYSA-N |
Jump to
- Bireociclib (XZP-3287,CDK4/6-IN-2) Solubility in DMSO
- Bireociclib (XZP-3287,CDK4/6-IN-2) Stock Solution
- Bireociclib (XZP-3287,CDK4/6-IN-2) Storage
- Bireociclib (XZP-3287,CDK4/6-IN-2) Stability
- Bireociclib (XZP-3287,CDK4/6-IN-2) SMILES
- Bireociclib (XZP-3287,CDK4/6-IN-2) CAS Number
- Bireociclib (XZP-3287,CDK4/6-IN-2) Chemical Structure (2D and 3D)
- Bireociclib (XZP-3287,CDK4/6-IN-2) SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.