Clinical Trials

Numerous clinical trials, spanning Phase 1 through Phase 4 along with integrated Phase 1/2 protocols, evaluate interventions across diverse populations and indications, including healthy volunteers, locally advanced pancreatic cancer, generalized myasthenia gravis, and coronary artery disease. Led by a mix of academic institutions and commercial sponsors such as Jazz Pharmaceuticals, Cabaletta Bio, and University College London, these studies represent various recruitment statuses, including active, recruiting, completed, and terminated.

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT06025331 RECRUITING
Arthroplasty, Replacement, Shoulder; Shoulder Osteoarthritis
Lovisenberg Diakonale Hospital
 2023-09-15
NCT06025448 RECRUITING
Arthroplasty Complications; Shoulder Osteoarthritis
Lovisenberg Diakonale Hospital
 2023-10-30
NCT07338539 RECRUITING
Glioma
Tata Memorial Centre
 2025-11-06
NCT07589959 NOT_YET_RECRUITING
Periodontal Bone Loss; Periodontal Defect; Periodontitis Stage III; Periodontitis Stage IV
Shashi Dadlani
 2026-05
NCT05705700 WITHDRAWN
Prostate Cancer
Masonic Cancer Center, University of Minnesota
 2023-02 PHASE2
NCT06458517 NOT_YET_RECRUITING
Head and Neck Neoplasms
Centre Paul Strauss
 2026-06-15
NCT05263804 RECRUITING
Ischemic Stroke
Hospices Civils de Lyon
 2022-05-22
NCT07412717 NOT_YET_RECRUITING
Nicotine Replacement Therapy; Healthcare Professionals; Tobacco Craving; Tabacco Cessation
Poitiers University Hospital
 2026-03-01
NCT07748871 NOT_YET_RECRUITING
Tooth Loss / Rehabilitation; Tooth Extraction; Alveolar Bone Loss; Alveolar Ridge Augmentation
University of Bern
 2026-10
NCT06989580 RECRUITING
Heart Failure; Arrhythmia; Decompensated Heart Failure; Atrial Fibrillation
Biotronik SE & Co. KG
 2025-08-22
NCT06487403 RECRUITING
Squamous Cell Carcinoma of Head and Neck
University Health Network, Toronto
 2025-04-17
NCT07805096 RECRUITING
Leukemia (Both ALL and AML); Brain Tumors
National Defense Medical University, Taiwan
 2025-12-30
NCT07470502 RECRUITING
IBD (Inflammatory Bowel Disease)
Meyer Children's Hospital IRCCS
 2025-02-13
NCT04741607 RECRUITING
Esthetics
University Ghent
 2021-01-01
NCT07434661 NOT_YET_RECRUITING
Valve Disease, Heart; Atrial Fibrillation (AF); Valve Replacement Surgery; Aortic Valve Surgery; Mitral Valve Annuloplasty; Mitral Valve Repair; Mitral Valve Surgery
Meshalkin Research Institute of Pathology of Circulation
 2026-02 PHASE3
NCT06914622 RECRUITING
Severe Mental Disorder; Severe Mental Illness
IRCCS Centro San Giovanni di Dio Fatebenefratelli
 2026-01-15
NCT07477899 ENROLLING_BY_INVITATION
Adverse Childhood Experiences; Developmental Risk; Psychomotor Development Disorders; Neurodevelopmental Disorders
IRCCS Eugenio Medea
 2024-06-26
NCT05959733 RECRUITING
Rotator Cuff Tears; Bioinductive Implant
Nova Scotia Health Authority
 2023-12-07
NCT07613502 RECRUITING
Amputation of Lower Limb Above Knee; Amputee; Amputation
University of Florida
 2026-06-01
NCT07640308 NOT_YET_RECRUITING
Severe Acute Respiratory Syndrome (SARS-CoV-2 Virus)
The Immunobiological Technology Institute (Bio-Manguinhos) / Oswaldo Cruz Foundation (Fiocruz)
 2026-07 PHASE1
NCT06732167 RECRUITING
Bone Regeneration
Aesculap AG
 2025-01-24
NCT07617272 RECRUITING
Prostate Cancer (Adenocarcinoma)
Region Stockholm
 2025-11-09 PHASE2
NCT07349290 ENROLLING_BY_INVITATION
Vitamin D Biofortification; Vitamin D Fortification; Vitamin D Status
University of Ulster
 2026-02-12
NCT07585721 NOT_YET_RECRUITING
Symptomatic Apical Periodontitis
Future University in Egypt
 2026-06-01
NCT06524635 RECRUITING
Hidradenitis Suppurativa; Atopic Dermatitis
AbbVie
 2024-08-14 PHASE2
NCT06085781 RECRUITING
Squamous Cell Carcinoma of Head and Neck
University Health Network, Toronto
 2024-01-29
NCT07161310 RECRUITING
Solid Cancer; Non-Small Cell Lung Cancer; Melanoma
Goethe University
 2026-01-02
NCT05947175 ACTIVE_NOT_RECRUITING
Degenerative Spine Diseases
Istituto Ortopedico Rizzoli
 2023-05-19
NCT06631729 RECRUITING
Eating Disorders
University of Minnesota
 2025-01-15
NCT04581304 ACTIVE_NOT_RECRUITING
Bone Loss; Missing Teeth
Rambam Health Care Campus
 2020-10-15
NCT07330154 RECRUITING
Wound Healing; Palatal Wound; Donor Site Complication; Inflammatory Cytokines
King Abdullah University Hospital
 2025-10-29
NCT05482282 WITHDRAWN
Diphtheria Vaccine Adverse Reaction; Tetanus Vaccine Adverse Reaction; Pertussis Vaccine Adverse Reaction; Haemophilus Influenzae Type B Vaccine Adverse Reaction; Hepatitis B Vaccine Adverse Reaction
PT Bio Farma
 2025-12 PHASE3
NCT06910007 NOT_YET_RECRUITING
Dental Implant
University of Baghdad
 2025-04-20
NCT06529913 RECRUITING
Allergic Contact Dermatitis; Metal Allergy; Food Allergy; Nickel Sensitivity; Nickel; Eczema; Aluminum Allergy; Chromium; Eczema; Functional Gastrointestinal Disorders; Respiratory Injury; Pollution; Exposure; Pollution Related Respiratory Disorder; Environmental Exposure; Environment Related Disease; Environmental Illness; Oxidative Stress; Risk Reduction
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
 2025-01-13
NCT07497503 RECRUITING
Healthy Volunteers
Syneos Health
 2026-04-10 PHASE1
NCT06646471 RECRUITING
Non Small Cell Lung Cancer; Lung Cancer
GFPC Investigation
 2024-09-26 PHASE4
NCT05312398 ACTIVE_NOT_RECRUITING
Metastatic Colorectal Adenocarcinoma
University of Campania Luigi Vanvitelli
 2021-07-15 PHASE2
NCT05377463 UNKNOWN
HIV Viremia
University of Texas, El Paso
 2023-05-10
NCT04293224 COMPLETED
Obesity; Body Weight
USDA, Western Human Nutrition Research Center
 2022-08-01
NCT07460869 ACTIVE_NOT_RECRUITING
Revascularization of Immature Young Permenant Teeth
Minia University
 2025-01-10
NCT07101029 NOT_YET_RECRUITING
Intracanal Dressing; Apical Periodontitis; Calcium Hydroxide; Biomarkers; Inflammatory Mediators
Cairo University
 2025-08 EARLY_PHASE1
NCT06453330 UNKNOWN
Osseointegration Failure of Dental Implant
University of Dublin, Trinity College
 2024-05-17
NCT03718637 RECRUITING
Tennis Elbow; Lateral Epicondylitis
Henry Ford Health System
 2019-04-17 PHASE4
NCT05074485 UNKNOWN
Pain
Alan Prossin
 2021-07-19 PHASE1
NCT05482295 NOT_YET_RECRUITING
Vaccine Reaction; Vaccine Adverse Reaction
PT Bio Farma
 2025-09 PHASE3
NCT06799910 RECRUITING
Congestion; RRT; UF; Bio-impendance Analysis; Fluid Removal; Diuretics; Overload
Centre Hospitalier Universitaire, Amiens
 2024-09-26
NCT04978844 UNKNOWN
Childhood Anxiety Disorder
Interdisciplinary Center Herzliya
 2021-04-01
NCT05805449 UNKNOWN
Anal Fistula
The University of Texas Health Science Center, Houston
 2023-02-21
NCT07344038 RECRUITING
Caries Active
Alexandria University
 2026-01-20
NCT07396688 COMPLETED
Postoperative Pain; Medicaments Substances in Therapeutic Use; Calcium Hydroxide; Root Canal Retreatment
Ankara University
 2025-09-25
NCT07752186 COMPLETED
Atrophic Acne Scars
Lahore General Hospital
 2025-08-10
NCT07125846 NOT_YET_RECRUITING
Alveolar Bone Loss; Maxillary Sinus Disease; Tooth Loss
Suez Canal University
 2025-10-15
NCT05068102 ACTIVE_NOT_RECRUITING
Carcinoma, Squamous Cell of Head and Neck (HNSCC); Melanoma; Non-small Cell Lung Cancer (NSCLC)
Boehringer Ingelheim
 2022-03-03 PHASE1
NCT06137235 ACTIVE_NOT_RECRUITING
Growth; Infections
FrieslandCampina
 2023-12-18
NCT07284680 ACTIVE_NOT_RECRUITING
Implant Assesment
Mansoura University
 2022-12-19
NCT06172114 UNKNOWN
Dental Implants; Tooth Extraction; Bone Regeneration
Mohammed Bin Rashid University of Medicine and Health Sciences
 2024-04-20
NCT07431736 ACTIVE_NOT_RECRUITING
Dentin Hypersensitivity
Hacettepe University
 2025-11-11
NCT06219824 UNKNOWN
Pulpotomy; Deep Caries
Cairo University
 2024-11-01 PHASE3
NCT06023979 NOT_YET_RECRUITING
Post Operative Treatment After Unstable Malleolar Fractures
Cantonal Hospital of St. Gallen
 2023-09-01
NCT06690515 NOT_YET_RECRUITING
Vaccine Adverse Reaction; Vaccine Reaction
PT Bio Farma
 2025-03-01 PHASE1; PHASE2
NCT07069231 NOT_YET_RECRUITING
Missing Tooth/Teeth
Universita degli Studi di Genova
 2025-07-15
NCT06543004 RECRUITING
Asymptomatic Apical Periodontitis
Primary Health Care Corporation, Qatar
 2024-10-28
NCT07146178 NOT_YET_RECRUITING
Gynecologic Surgery; General Anesthesia
Wonju Severance Christian Hospital
 2025-09-01
NCT05695924 RECRUITING
Lymphedema; Edema
Fibralign Corporation
 2023-11-01
NCT06962670 RECRUITING
Breast Cancer; Lung Cancer; Colorectal Cancer; Gynecologic Cancer
University of Erlangen-Nürnberg Medical School
 2024-09-14
NCT06992349 NOT_YET_RECRUITING
Dysmenorrhea Primary; Obesity and Overweight
Alaa Noureldeen Kora
 2025-08-01
NCT06741345 COMPLETED
Healthy Volunteer Study
Humanetics Corporation
 2024-12-23 PHASE1
NCT06551818 COMPLETED
Androgenic Alopecia
NovoBliss Research Pvt Ltd
 2024-09-23
NCT07210177 ACTIVE_NOT_RECRUITING
Root Canal Treatment; Intracanal Medicament; Post Operative Pain; Apical Periodontitis
Ege University
 2024-08-01
NCT06793514 NOT_YET_RECRUITING
Probiotic; Ocular Surface Disease; Ocular Diseases; Ocular Dryness; Gut Microbiome Dysbiosis; Gut -microbiota
Mohsen Pourazizi
 2025-02-01 PHASE1
NCT06913673 NOT_YET_RECRUITING
Endodontic Disease
Minia University
 2025-04-01 PHASE2
NCT06252935 RECRUITING
Guided Tissue Regeneration; Collagen Membrane; Dental Diseases
Maxigen Biotech Inc.
 2024-07-30
NCT05902689 ACTIVE_NOT_RECRUITING
Alveolar Bone Resorption
Second Affiliated Hospital, Zhejiang University, School of Medicine
 2023-06-15
NCT04705623 RECRUITING
Postmenopausal; Postmenopausal Flushing
Insel Gruppe AG, University Hospital Bern
 2020-09-01
NCT05100823 TERMINATED
Cystic Fibrosis; CFTR Gene Mutation
University Hospital, Montpellier
 2022-03-30
NCT05920018 UNKNOWN
Multiple Sclerosis, Relapsing-Remitting
Universität Münster
 2023-10-02
NCT06532526 UNKNOWN
Tooth Discoloration
King Abdullah University Hospital
 2024-07-01
NCT06689995 COMPLETED
Upper Respiratory Tract Infection
NovoBliss Research Pvt Ltd
 2024-12-30
NCT06970379 COMPLETED
Posterior Mandibular Fractures
Alexandria University
 2024-03-30
NCT05227352 COMPLETED
Mental Health; Cognition; Anxiety
Icahn School of Medicine at Mount Sinai
 2022-09-27
NCT06640270 NOT_YET_RECRUITING
Diabetes
Home Habilis
 2024-10-15
NCT02599116 UNKNOWN
Pseudomyxoma Peritonei; Appendiceal Neoplasm; Cancer, Appendiceal
Mercy Medical Center
 2015-12
NCT02320656 COMPLETED
Acute Leukemia; Myelodysplastic Syndromes; Myeloproliferative Disorders
Institut Paoli-Calmettes
 2014-05
NCT06631898 COMPLETED
Normal Skin
NovoBliss Research Pvt Ltd
 2024-10-09
NCT06440889 COMPLETED
Varicose Veins with Self-declared Knee Pain
NovoBliss Research Pvt Ltd
 2024-05-31
NCT04597840 UNKNOWN
Ventral Hernia Repair
Hospices Civils de Lyon
 2021-05-25
NCT05627284 UNKNOWN
Stoma Site Incisional Hernia
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
 2022-10-01
NCT06876389 COMPLETED
Iron Deficiency (ID)
Hasanuddin University
 2024-07-01
NCT06337422 Not yet recruiting
Healthy Volunteer
International Bio service
 2024-09-23 Phase 1
NCT04276857 Not yet recruiting
Locally Advanced Pancreatic Cancer|Irreversible Electroporation
University of Saskatchewan
 2024-09-01 Not Applicable
NCT05529108 UNKNOWN
Metabolic Syndrome; Diabetes
National University of Singapore
 2022-10-28
NCT05933278 COMPLETED
COVID-19
PT Bio Farma
 2023-07-25 PHASE2
NCT05692518 COMPLETED
Type 2 Diabetes; Obesity
GT Metabolic Solutions, Inc.
 2022-12-19
NCT06574815 COMPLETED
Dental Implantation; Guided Bone Regeneration
Beijing Stomatological Hospital, Capital Medical University
 2023-04-30
NCT06330792 UNKNOWN
Mechanical Low Back Pain
Cairo University
 2024-05-04
NCT06359041 Not yet recruiting
Generalized Myasthenia Gravis (gMG)
Cabaletta Bio
 2024-08 Phase 1|Phase 2
NCT04482595 UNKNOWN
COVID-19; Long COVID; Pulmonary Fibrosis; Post-acute Respiratory Complications of COVID-19
Humanetics Corporation
 2020-11-11 PHASE2
NCT05018130 UNKNOWN
Flatfoot; Bone Resorption; Cavus Deformity; Osteolysis; Complication
University of Iowa
 2021-11-01
NCT05938114 UNKNOWN
Alveolar Ridge Augmentation
University of Central Lancashire
 2024-01
NCT04471311 UNKNOWN
Incisional Hernia After Midline Laparotomy
Azienda Sanitaria Locale Napoli 2 Nord
 2024-01-01
NCT05928858 UNKNOWN
Indirect Pulp Capping
Cairo University
 2023-09 PHASE3
NCT06167525 UNKNOWN
Neck Pain Musculoskeletal
Royal College of Surgeons, Ireland
 2024-01-18
NCT06433141 UNKNOWN
Primary Teeth
Al-Azhar University
 2023-12-19
NCT06338410 COMPLETED
Kangaroo Mother Care; Oxidative Stress
University of Health Sciences Lahore
 2023-08-01
NCT05255081 COMPLETED
Surgical Adhesions
The University of Hong Kong
 2022-03-01
NCT03766022 COMPLETED
Dental Implants,Peri-implantitis,Smoking
Rambam Health Care Campus
 2019-01-22
NCT06108999 UNKNOWN
Wound Heal; Wound; Foot
Fidia Farmaceutici s.p.a.
 2022-07-29
NCT06297018 TERMINATED
Mental Health Issue
Istanbul Aydın University
 2024-01-01
NCT05937802 UNKNOWN
Progressive Multiple Sclerosis
Ospedale Policlinico San Martino
 2023-01-02
NCT05912959 COMPLETED
Cerebral Palsy; Cerebral Palsy, Spastic
University of Hail
 2023-08-15
NCT04830592 COMPLETED
Squamous Cell Carcinoma of the Head and Neck
Akamis Bio
 2021-11-04 PHASE1
NCT03394612 COMPLETED
Skin Wound
CUTISS AG
 2018-02-14 PHASE2
NCT04994561 WITHDRAWN
Aging
Vitality in Aging Research Group, Inc.
 2022-06 PHASE1
NCT03755466 UNKNOWN
Rheumatoid Arthritis
Shinshu University
 2018-11-21 PHASE2
NCT03282890 COMPLETED
Risk Behavior; HIV/AIDS; Medication Adherence; Substance Abuse
University of Connecticut
 2017-11-20
NCT05645900 COMPLETED
Influenza
Ab&B Bio-tech Co., Ltd.JS
 2023-02-06 PHASE3
NCT06686836 COMPLETED
Patients with Posterior Maxillary Atrophy and Need for Sinus Lift Surgery to Allow Implant Placement
University of Santiago de Compostela
 2022-06-22 PHASE4
NCT03735199 COMPLETED
Bone Resorption After Tooth Extraction
National Dental Centre, Singapore
 2019-02-28
NCT05601414 COMPLETED
Hypertension
Yale University
 2023-01-11
NCT06686004 COMPLETED
Absorption, Metabolism and Excretion in Healthy Volunteers; Bioavailability and AUC
Newcastle University
 2022-08-01
NCT05918939 UNKNOWN
COVID-19 Pandemic; COVID-19 Vaccines
Dr. Soetomo General Hospital
 2022-09-05 EARLY_PHASE1
NCT05460377 COMPLETED
Poliomyelitis
Centers for Disease Control and Prevention
 2022-07-26 PHASE4
NCT05525208 COMPLETED
COVID-19
PT Bio Farma
 2022-09-01 PHASE2
NCT05912322 UNKNOWN
Essential Hypertension; Endothelial Dysfunction; Inflammation
University of Medicine and Pharmacy "Victor Babes" Timisoara
 2022-06-01
NCT03070496 COMPLETED
STEMI - ST Elevation Myocardial Infarction
Hospices Civils de Lyon
 2017-03-07
NCT04758702 COMPLETED
Lack of Keratinized Gingiva
Abdo Y Ismail
 2021-02-24 PHASE1
NCT05887193 COMPLETED
Healthy; Cyclists; Blood Gas Monitoring, Transcutaneous; Penile Numbness
Milan Martínek
 2023-04-21
NCT05314842 UNKNOWN
Caries
Sarah Abdelbar Mahmoud
 2022-04-01 PHASE3
NCT02592330 COMPLETED
Limbal Stem Cell Deficiency
Massachusetts Eye and Ear Infirmary
 2016-08-01 PHASE1; PHASE2
NCT05508477 UNKNOWN
COVID-19 Pandemic; COVID-19 Vaccines
Dr. Soetomo General Hospital
 2022-06-28 PHASE3
NCT04956900 COMPLETED
Venous Leg Ulcer; Leg Injuries and Disorders
SolasCure Limited
 2021-08-09 PHASE2
NCT04585100 UNKNOWN
Ocular Hypertension
Future Medicine
 2020-10-07 PHASE1; PHASE2
NCT05486052 COMPLETED
Rehabilitation; Biofeedback; Neurological Diseases
University of Rzeszow
 2022-08-01
NCT04914325 COMPLETED
Patient Satisfaction; Gingival Bleeding
Cairo University
 2021-10-22 PHASE4
NCT05443477 UNKNOWN
Premenstrual Syndrome
Chung Shan Medical University
 2021-06-08
NCT05597553 UNKNOWN
Indirect Pulp Capping
Cairo University
 2023-01-01
NCT04488458 UNKNOWN
Prosthetic Joint Infection; Prosthetic Infection; Hip Prosthesis Infection; Knee Prosthesis Infection
Vastra Gotaland Region
 2021-08-15
NCT04243993 UNKNOWN
Clinical Outcome; Endodontic Disease
Mahidol University
 2017-07-01
NCT06008236 COMPLETED
Stress; Stress, Physiological
Saglik Bilimleri Universitesi
 2022-11-12
NCT04323670 COMPLETED
Pacemaker DDD
Biotronik SE & Co. KG
 2020-10-08
NCT03022708 ACTIVE_NOT_RECRUITING
Heart Defect, Congenital
Xeltis
 2017-05-08
NCT04568707 COMPLETED
Covid19; Neurologic Manifestations; Psychiatric Manifestations
Assistance Publique - Hôpitaux de Paris
 2020-10-23
NCT05800496 COMPLETED
Hair Thinning; Hair Brittle; Dry Hair
NovoBliss Research Pvt Ltd
 2022-10-31
NCT03227146 COMPLETED
Burns
CUTISS AG
 2017-10-25 PHASE2
NCT06111911 COMPLETED
Human Papilloma Virus Infection
PT Bio Farma
 2022-04-01
NCT06914089 COMPLETED
Primary Percutaneous Coronary Intervention
Assiut University
 2020-10-01
NCT04167176 COMPLETED
Postoperative Pain
Assiut University
 2020-09-15
NCT03294720 COMPLETED
ACL - Anterior Cruciate Ligament Rupture
Andrews Research & Education Foundation
 2018-01-08 PHASE1
NCT04596124 UNKNOWN
Wound Heal; Wound Infection; Wounds and Injuries
Farmaceutici Damor Spa
 2020-09-18
NCT04431323 COMPLETED
Multiple Sclerosis
Azienda Ospedaliera Universitaria Integrata Verona
 2020-05-13
NCT04922372 UNKNOWN
Surface Roughness
Cairo University
 2021-07-22 PHASE4
NCT03395145 COMPLETED
Bio-Oss; Mucograft
Rambam Health Care Campus
 2018-05-27
NCT04872140 COMPLETED
Iron-deficiency
University of Saskatchewan
 2021-05-03
NCT05716698 COMPLETED
Healthy
Taipei Medical University
 2022-04-15
NCT05162495 UNKNOWN
COVID-19
Tera Group
 2022-01-01
NCT05124340 COMPLETED
BCG Vaccination Reaction
PT Bio Farma
 2021-12-01 PHASE2
NCT04618874 COMPLETED
Lung Cancer
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
 2021-03-15
NCT04305340 COMPLETED
Heart Failure
Aamir Jeewa
 2021-09-15
NCT03666897 COMPLETED
Stroke
Corewell Health West
 2018-10-01
NCT06656741 COMPLETED
Breath Training Styles
Hei-Yin Hydra Ng
 2021-05-11
NCT05399303 COMPLETED
Endodontically Treated Teeth; Post Operative Pain
Misr International University
 2022-01-01
NCT04824235 COMPLETED
Alveolar Ridge Preservation
Hams Hamed Abdelrahman
 2020-12-01
NCT03869671 WITHDRAWN
Intravenous Drug Abuse
Boston University
 2021-03
NCT03740698 TERMINATED
Diabetes Mellitus, Type 1
Imperial College London
 2021-02-01
NCT04706572 UNKNOWN
Rehabilitation; Parkinson Disease; Locomotion Disorder, Neurologic; Rhythm; Abnormal
I.R.C.C.S. Fondazione Santa Lucia
 2020-06-15
NCT05104879 UNKNOWN
Joint Diseases, Midlevel Providers, Nurse Practitioners, Physician Assistants, Patient Perceptions, Patient Preferences
Desert Orthopedic Center
 2021-12
NCT03912246 COMPLETED
Infectious Disease; Tropical Disease
Institut Pasteur
 2009-04-27
NCT02312518 UNKNOWN
Venous Leg Ulcers
PRP Concepts, LLC
 2021-01-01
NCT03798743 COMPLETED
Non-small Cell Lung Cancer
Hunan Province Tumor Hospital
 2019-01-01 PHASE2
NCT04338516 COMPLETED
TEETH EXTRACTION
Datum Dental LTD
 2019-11-01
NCT04195282 UNKNOWN
Hepatitis B; Acute-On-Chronic Liver Failure
Third Affiliated Hospital, Sun Yat-Sen University
 2019-12
NCT03753854 TERMINATED
Sickle Cell Disease
Hospices Civils de Lyon
 2018-05-28
NCT01633541 COMPLETED
Laryngeal Cancer
University of Michigan Rogel Cancer Center
 2012-03 PHASE2
NCT02341534 COMPLETED
Myocardial Infarction; Myocardial Infarction, Acute; Myocardial Infarction Old
Biotronik SE & Co. KG
 2015-08-07
NCT05519514 COMPLETED
Healthy Subjects; Human Volunteers; Healthy Participants; Bioequivalence
Abbott
 2021-07-12 PHASE1
NCT04658264 UNKNOWN
Barley/Wheat Composite Flour in Type-2 Diabetes
University of Veterinary and Animal Sciences, Lahore - Pakistan
 2021-01-15 PHASE1
NCT04650555 COMPLETED
Acute Radiation Syndrome
Humanetics Corporation
 2020-12-08 PHASE1
NCT05114772 COMPLETED
Atrial Fibrillation
Tanta University
 2019-07-01
NCT04025710 COMPLETED
Tachyarrhythmia; Atrial Fibrillation (AF); Syncope; Cryptogenic Stroke
Biotronik SE & Co. KG
 2019-10-17
NCT04688294 COMPLETED
Heart Failure
Amir Safwat
 2020-01-01 PHASE4
NCT03636581 COMPLETED
Overweight
New York Institute of Technology
 2018-08-08
NCT03374813 UNKNOWN
Alveolar Ridge Preservation
Mimetis Biomaterials S.L.
 2017-11-16
NCT04071379 COMPLETED
Immunogenicity; Safety
PT Bio Farma
 2020-10-13 PHASE3
NCT05989035 COMPLETED
Aging
AdventHealth Translational Research Institute
 2020-08-31
NCT04482790 UNKNOWN
Gingival Black Triangle
Cairo University
 2020-03-01
NCT04554641 COMPLETED
Microbial Colonization
The Functional Gut Clinic
 2019-11-01
NCT04249336 COMPLETED
Dentin Hypersensitivity
Dow University of Health Sciences
 2019-09-27 PHASE3
NCT04508075 COMPLETED
SARS-CoV2 Infection
PT Bio Farma
 2020-08-10 PHASE3
NCT04546347 COMPLETED
Healthy Volunteers
AstraZeneca
 2020-09-17 PHASE1
NCT03175146 UNKNOWN
Colonic Neoplasms; Neoplasm Metastasis
AHS Cancer Control Alberta
 2017-09
NCT04526340 COMPLETED
Nocturia; Polyuria
University Hospital, Ghent
 2019-06-24
NCT04577053 TERMINATED
Lyme Disease; Lyme Neuroborreliosis; Lyme Arthritis; Unknown Origin Fever
Kasey Phifer
 2020-10-07
NCT03750214 UNKNOWN
Cervical Cancer Screening
BIOP Medical
 2020-05
NCT02658032 COMPLETED
Smoking Cessation; Biofeedback
Yale University
 2016-01
NCT04381598 UNKNOWN
Periodontitis
SVS Institute of Dental Sciences
 2019-04-01 PHASE2
NCT03464786 COMPLETED
Tooth Extraction
Shenzhen Lando Biomaterials Co., Ltd.
 2018-04-03
NCT05445362 COMPLETED
Effects of the Elements
Reham Hassan
 2019-02-01
NCT04146740 COMPLETED
Gestational Diabetes Mellitus
Foundation University Islamabad
 2019-03-12
NCT03801655 UNKNOWN
Mood; Cognitive Change
University of Oxford
 2018-08-15
NCT03526640 UNKNOWN
Computed Tomography, Biopsy, Pneumothorax, Chest Tube, Plug
University Hospital, Akershus
 2018-05-04
NCT03726008 TERMINATED
Gestational Diabetes
Kaohsiung Medical University Chung-Ho Memorial Hospital
 2018-01-22
NCT04188223 COMPLETED
Hepatitis B
PT Bio Farma
 2019-12-03 PHASE1
NCT02942277 COMPLETED
Malaria
National Institute of Allergy and Infectious Diseases (NIAID)
 2016-10-21 PHASE1
NCT03059914 COMPLETED
Missing Teeth
Loma Linda University
 2017-08-10
NCT02999152 TERMINATED
Bone Metastasis; Malignant Hemopathy
Centre Hospitalier Universitaire de Saint Etienne
 2017-06-22
NCT04144673 COMPLETED
Healthy
Natural Immunogenics Corp.
 2019-11-14
NCT03724474 UNKNOWN
Physical Activity; Poor Quality Sleep; Hypertension
University of Delaware
 2018-11-01
NCT04334473 COMPLETED
Glaucoma; Cataract
Mai Nasser Abd Elmohsen
 2019-09-20
NCT05135741 COMPLETED
Forward Head Posture
Bahria University
 2020-01-10
NCT03995615 UNKNOWN
Periodontitis and Rheumatoid Arthritis
Krishnadevaraya College of Dental Sciences & Hospital
 2020-01
NCT03156504 COMPLETED
Major Depression; Bipolar I Disorder; Bipolar II Disorder; Unipolar Depression
Mayo Clinic
 2017-06-01 PHASE4
NCT03742947 COMPLETED
Postpartum Hemorrhage; Hyperfibrinolysis
University Hospital, Bordeaux
 2019-01-10
NCT04127877 UNKNOWN
Chronic Kidney Diseases; Hemodialysis Complication
Assuta Ashdod Hospital
 2018-11-18
NCT03460405 COMPLETED
Safety Issues; Immunogenicity
PT Bio Farma
 2018-07-16 PHASE2
NCT02384291 UNKNOWN
Sinus Floor Augmentation
Alpha - Bio Tec Ltd.
 2014-05
NCT03975205 UNKNOWN
Lymphoma Leukemia
Sutphin Drugs
 2019-07-01 EARLY_PHASE1
NCT04557657 UNKNOWN
Resin Cement
Cairo University
 2019-09-01 PHASE1
NCT03850327 COMPLETED
Atrial Fibrillation; Syncope; Tachyarrhythmia
Biotronik SE & Co. KG
 2019-03-08
NCT03697005 UNKNOWN
Clinical Performance; Patient Satisfaction
Cairo University
 2018-10-01
NCT04704375 COMPLETED
Musculoskeletal Pain
Lake Erie College of Osteopathic Medicine
 2018-09-13
NCT03823612 UNKNOWN
White Spot Lesion of Tooth
Cairo University
 2019-03-01 PHASE4
NCT05529238 COMPLETED
Urinary Incontinence,Stress
Charles Darwin University
 2019-06-18
NCT04216030 COMPLETED
Iron-deficiency; Iron Deficiency Anemia; Iron Deficiency (Without Anemia)
Swiss Federal Institute of Technology
 2019-05-14
NCT02959281 WITHDRAWN
Cardio-Renal Syndrome
HaEmek Medical Center, Israel
 2018-06-01
NCT03014050 COMPLETED
Parkinson Disease
Boston University
 2017-09-22 EARLY_PHASE1
NCT02991781 COMPLETED
Chronic Obstructive Pulmonary Disease (COPD); Asthma; Smoking
Aristotle University Of Thessaloniki
 2017-01
NCT02858570 UNKNOWN
Serogroup C Meningococcal Meningitis
The Immunobiological Technology Institute (Bio-Manguinhos) / Oswaldo Cruz Foundation (Fiocruz)
 2018-09-25 PHASE2; PHASE3
NCT02567799 COMPLETED
Carcinoma, Non-Small-Cell Lung
Humanetics Corporation
 2015-11 PHASE1; PHASE2
NCT03139227 WITHDRAWN
Health Status Unknown
Ohio State University Comprehensive Cancer Center
 2017-08-15
NCT04381403 COMPLETED
Calculus, Dental; Periodontal Diseases; Periodontal Inflammation
Faleh Tamimi
 2017-02-01
NCT03272594 COMPLETED
Pain; Neonatal
Britney Benoit
 2017-11-29 PHASE3
NCT05861388 COMPLETED
Edentulous Alveolar Ridge
Tanta University
 2017-01-15
NCT04494191 COMPLETED
Healthy
Genuine Research Center, Egypt
 2018-12-12 PHASE1
NCT03516409 UNKNOWN
Acute Otitis Media
Probiotics International Ltd.
 2018-04-18
NCT03993431 COMPLETED
Deep Caries
Fayoum University
 2015-07
NCT02387008 TERMINATED
Bone Regeneration
University of North Carolina, Chapel Hill
 2017-06-30
NCT03569683 COMPLETED
Gingival Overgrowth
Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre
 2018-05-30
NCT03430726 UNKNOWN
Healthy
McMaster University
 2018-03-01
NCT03018717 UNKNOWN
Chronic Lung Disease; Chronic Heart Disease
Fundación Pública Andaluza Progreso y Salud
 2016-06-13
NCT03822767 COMPLETED
Poliomyelitis
Sinovac Biotech Co., Ltd
 2018-06-12 PHASE3
NCT03677921 COMPLETED
Normal Healthy Subjects
Yonsei University
 2017-12-10
NCT02174198 COMPLETED
Tooth Loss
Columbia University
 2014-01
NCT02984137 COMPLETED
Parkinson Disease; REM Sleep Behavior Disorder
Seoul National University Hospital
 2013-06
NCT02844478 COMPLETED
Stress, Psychological; Telomere Shortening; Stress, Physiological
The University of Texas Health Science Center at San Antonio
 2016-09
NCT03239275 COMPLETED
Malocclusion, Angle Class II, Division 1
Ain Shams University
 2016-01-17
NCT03263403 COMPLETED
Meningococcal Vaccine
International Centre for Diarrhoeal Disease Research, Bangladesh
 2017-08-21 PHASE2; PHASE3
NCT02991495 COMPLETED
Yellow Fever
Epicentre
 2017-11-06 PHASE4
NCT02753439 UNKNOWN
Impacted Third Molar Tooth
The Baruch Padeh Medical Center, Poriya
 2017-02
NCT04036578 COMPLETED
Pelvic Floor Dysfunction
Far Eastern Memorial Hospital
 2015-12-01
NCT02929173 UNKNOWN
Personal Satisfaction
Cairo University
 2017-01 PHASE2
NCT01397175 TERMINATED
Coronary Artery Disease
Yonsei University
 2013-01-16
NCT04498884 COMPLETED
Bioequivalence
Geropharm
 2017-07-18
NCT02817165 TERMINATED
Acute Diarrhea
The Hospital for Sick Children
 2016-11
NCT03109600 COMPLETED
Safety Issues
PT Bio Farma
 2017-04-18 PHASE1
NCT02662127 UNKNOWN
Chronic Venous Insufficiency
London North West Healthcare NHS Trust
 2016-04
NCT02648126 UNKNOWN
Red-Cell Aplasia, Pure; Renal Insufficiency, Chronic
The Immunobiological Technology Institute (Bio-Manguinhos) / Oswaldo Cruz Foundation (Fiocruz)
 2015-11 PHASE4
NCT02997410 UNKNOWN
Orofacial Pain; Temporomandibular Joint Disorders
Istanbul University
 2014-12
NCT01853306 COMPLETED
Oncology; BRCA Mutated; High Grade Serous Ovarian Cancer; BRCA Mutated Breast Cancer
AbbVie
 2013-03-18 PHASE1
NCT02683759 UNKNOWN
Ulcerative Colitis
Asian Institute of Gastroenterology, India
 2016-02 PHASE3
NCT02683733 UNKNOWN
Ulcerative Colitis
Asian Institute of Gastroenterology, India
 2016-02 PHASE3
NCT03621683 COMPLETED
Ovarian Reserve
Lucy Coleman
 2016-01-06
NCT03354182 COMPLETED
Furcation Defects
Cliniques universitaires Saint-Luc- Université Catholique de Louvain
 2015-07-30
NCT05187663 COMPLETED
Peri-Implantitis
University of Belgrade
 2014-01
NCT02033759 COMPLETED
Anxiety
Mercy Research
 2014-06
NCT00941356 WITHDRAWN
MRSA Colonization
Bio-K Plus International Inc.
 2010-01 PHASE2
NCT02434770 COMPLETED
Poliomyelitis
PATH
 2015-08 PHASE3
NCT03149172 COMPLETED
Alveolar Bone Loss
Tufts University
 2014-10-20
NCT02738931 COMPLETED
Infection, Human Immunodeficiency Virus
ViiV Healthcare
 2016-05 PHASE1
NCT01911819 COMPLETED
Inadequate Bone Height in Maxillary Posterior Area
Loma Linda University
 2013-12
NCT01045980 COMPLETED
Disorders Associated With Peritoneal Dialysis
St. Joseph's Healthcare Hamilton
 2010-08-01 PHASE2
NCT01738347 COMPLETED
Relapsing-remitting Multiple Sclerosis (rrMS)
GE Healthcare
 2013-04 PHASE1
NCT03251625 COMPLETED
Irritable Bowel Syndrome
Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
 2015-04 PHASE4
NCT02927028 COMPLETED
Obesity
Purdue University
 2015-08-01
NCT05065177 COMPLETED
Mumps
Sinovac Research and Development Co., Ltd.
 2016-01 PHASE3
NCT02692599 COMPLETED
Mumps
Sinovac (Dalian) Vaccine Technology Co., Ltd.
 2016-01 PHASE3
NCT02373787 TERMINATED
Implant
Nobel Biocare
 2013-07
NCT05145621 COMPLETED
Bioequivalence; Safety
Alembic Pharmaceuticals Ltd.
 2015-10-29 PHASE1
NCT01202630 SUSPENDED
Recurrent Clostridium Difficile Infection
Bio-K Plus International Inc.
 2010-06 PHASE3
NCT02650869 COMPLETED
Necrotizing Enterocolitis
Sylhet M.A.G.Osmani Medical College
 2012-07 PHASE3
NCT01991899 COMPLETED
Measles; Mumps; Rubella; Varicella
The Immunobiological Technology Institute (Bio-Manguinhos) / Oswaldo Cruz Foundation (Fiocruz)
 2015-02 PHASE3
NCT02292927 COMPLETED
Aortic Aneurysm
Imperial College London
 2014-11
NCT02865590 COMPLETED
Maxillary Sinus Floor Augmentation
University of L'Aquila
 2011-06
NCT02605798 COMPLETED
Healthy
Genuine Research Center, Egypt
 2015-08 PHASE1
NCT02177851 COMPLETED
Iron Deficiency; Anemia; Iron Deficiency Anemia
Swiss Federal Institute of Technology
 2015-06
NCT01875874 TERMINATED
Acute Liver Failure; Fulminant Hepatic Failure; Primary Graft Non-Function; Surgically-Induced Liver Failure
Vital Therapies, Inc.
 2014-10 PHASE2
NCT01412307 UNKNOWN
Recurrent Adult Hodgkin Lymphoma
Istituto Nazionale Tumori IRCCS - Fondazione G. Pascale
 2011-07 PHASE1; PHASE2
NCT02208557 UNKNOWN
Incisional Hernia
Hospital Universitari Vall d'Hebron Research Institute
 2014-07 PHASE4
NCT02364193 COMPLETED
Pulmonary Congestion
Catharina Ziekenhuis Eindhoven
 2015-03
NCT02379481 COMPLETED
Healthy Adults With Subjective Memory Complaints
Ewha Womans University
 2013-07
NCT02437955 COMPLETED
Anemia; Deficiency, Nutritional, With Poor Iron Absorption
Swiss Federal Institute of Technology
 2015-04
NCT01654627 UNKNOWN
Jaw, Edentulous; Jaw, Edentulous, Partially
RegeneCure, Ltd.
 2013-04 PHASE1; PHASE2
NCT01958905 COMPLETED
Malaria; Severe Acute Malnutrition
Epicentre
 2013-11
NCT01929954 TERMINATED
Edentulous Alveolar Ridge
Organogenesis
 2013-07 PHASE1; PHASE2
NCT02066441 COMPLETED
Family Member
University of Miami
 2014-02
NCT02325713 COMPLETED
Healthy
Merck KGaA, Darmstadt, Germany
 2015-01 PHASE1
NCT02021084 WITHDRAWN
Familial Mediterranean Fever (FMF )
Rambam Health Care Campus
 2013-12
NCT01116219 COMPLETED
Lung Cancer
Swiss Cancer Institute
 2010-06 PHASE2
NCT01788150 COMPLETED
Coronary Artery Disease
Svelte Medical Systems, Inc.
 2013-01
NCT03134924 COMPLETED
Vaginosis, Bacterial
University of Miami
 2013-05-03
NCT01765998 UNKNOWN
Crohn's Disease
The Baruch Padeh Medical Center, Poriya
 2013-02 PHASE4
NCT01849185 UNKNOWN
Hypercholesterolemia
Meir Medical Center
 2013-05 PHASE4
NCT01735617 COMPLETED
Endocrine Disease; Adrenal Insufficiency; Congenital Adrenal Hyperplasia
Neurocrine UK Limited
 2012-12 PHASE2
NCT02513368 COMPLETED
Oral Soft Tissue Conditions
University of Firenze and Siena, Napoli, Italy
 2011-01 PHASE2
NCT01681381 UNKNOWN
Ischemic Heart Disease; Myocardial Ischemia; Coronary Artery Lesions,Primary; Coronary Disease; Acute Coronary Syndrome; Furcation Lesion of Coronary Artery
Essen Technology (Beijing) Co., Ltd.
 2012-09
NCT01681030 COMPLETED
Cardiovascular Disease
Ethicon, Inc.
 2012-08-01 PHASE2
NCT00819923 UNKNOWN
Acute Coronary Syndrome
The Hospital District of Satakunta
 2008-11 PHASE3
NCT01712906 COMPLETED
Mumps
Institute of Medical Biology, Chinese Academy of Medical Sciences
 2012-10 PHASE1
NCT01956097 COMPLETED
Healthy Adults With Subjective Memory Complaints
Ewha Womans University
 2012-03
NCT01777529 COMPLETED
Measles; Mumps; Rubella
The Immunobiological Technology Institute (Bio-Manguinhos) / Oswaldo Cruz Foundation (Fiocruz)
 2012-10 PHASE4
NCT01671475 COMPLETED
Altered Mental Status
Bio-Signal Group Corp.
 2012-08 PHASE2
NCT01136915 TERMINATED
Coronary Artery Stenosis
Bracco Diagnostics, Inc
 2010-11 PHASE4
NCT01644422 UNKNOWN
Androgenetic Alopecia
Kasiak Research Pvt. Ltd.
 2012-01 PHASE1; PHASE2
NCT01643629 UNKNOWN
Androgenetic Alopecia
Kasiak Research Pvt. Ltd.
 2012-01 PHASE1; PHASE2
NCT01138748 TERMINATED
Inoperable Early Stage Non-small Cell Lung Cancer
University Hospital, Ghent
 2010-11 PHASE2
NCT01405287 COMPLETED
Coronary Artery Disease; Atherosclerosis; Acute Coronary Syndrome (ACS); Myocardial Infarction (MI)
OrbusNeich
 2011-10 PHASE2
NCT01222832 COMPLETED
Paranasal Sinus Disease
Steward St. Elizabeth's Medical Center of Boston, Inc.
 2010-07 PHASE2
NCT01087411 WITHDRAWN
Cardiovascular Risk Factors; Metabolic Risk Factors; Sedentary Lifestyle; Overweight
Karolinska Institutet
 2008-10
NCT02107079 COMPLETED
Pharmacokinetics of Melatonin
Utrecht University
 2012-01
NCT01986322 COMPLETED
Healthy
PT Bio Farma
 2011-07 PHASE2
NCT01259635 UNKNOWN
Parkinson's Disease
Tel-Aviv Sourasky Medical Center
 2011-01
NCT01082822 UNKNOWN
Chronic Periodontitis
Air Force Military Medical University, China
 2010-01 PHASE1; PHASE2
NCT01511744 COMPLETED
Human Influenza
Hualan Biological Engineering, Inc.
 2011-11 PHASE4
NCT01381276 COMPLETED
Vitamin A Deficiency
USDA, Western Human Nutrition Research Center
 2011-06 PHASE2
NCT01070849 COMPLETED
Low Back Pain
University of Erlangen-Nürnberg
 2009-11 PHASE2; PHASE3
NCT01012921 COMPLETED
Degeneration; Bone
Institut Straumann AG
 2009-09
NCT00977925 COMPLETED
Soft Tissue Bleeding
Ethicon, Inc.
 2009-08 PHASE3
NCT01638143 COMPLETED
Bioequivalence; Bioavailability
Maastricht University Medical Center
 2010-11
NCT00863174 COMPLETED
Multiple Myeloma
Sun Pharma Advanced Research Company Limited
 2010-11 PHASE1
NCT01062347 COMPLETED
Zinc Deficiency
International Centre for Diarrhoeal Disease Research, Bangladesh
 2007-07-01 PHASE1
NCT01480947 COMPLETED
Gastroenteritis; Diarrhea
Kaohsiung Veterans General Hospital.
 2009-02 PHASE4
NCT01977170 COMPLETED
Healthy
PT Bio Farma
 2010-11 PHASE1
NCT01900587 COMPLETED
Healthy
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
 2010-07 PHASE1
NCT01055769 COMPLETED
Healthy Volunteers
Pfizer
 2010-03 PHASE1
NCT00315250 COMPLETED
Parkinson's Disease; Parkinsonian Syndrome
Institute for Neurodegenerative Disorders
 2006-01 PHASE2
NCT01042327 COMPLETED
Chronic Kidney Disease
Royal Free Hampstead NHS Trust
 2009-02 PHASE4
NCT00716261 UNKNOWN
Parkinson's Disease Patients
Tel-Aviv Sourasky Medical Center
 2008-01
NCT00655057 COMPLETED
Depression
University of Pennsylvania
 2005-10 PHASE2; PHASE3
NCT01250249 COMPLETED
Healthy
Green Signal Biopharma Private Limited
 2008-11 PHASE3
NCT00792844 UNKNOWN
Antibiotic-Associated Diarrhea
McMaster University
 2009-02
NCT00678847 UNKNOWN
Chronic Venous Leg Ulcers
Kingfisher Healthcare
 2008-03 PHASE2; PHASE3
NCT00477893 UNKNOWN
Spondyloarthritis
Glostrup University Hospital, Copenhagen
 2006-02 PHASE4
NCT00316706 COMPLETED
Cervical Intraepithelial Neoplasia; Papillomavirus Infection
GlaxoSmithKline
 2005-10 PHASE3
NCT00426322 COMPLETED
Sinus Graft
Hadassah Medical Organization
 2007-03
NCT01184495 COMPLETED
Comparison of the Efficacy of Two Formulations of Epoetin in Patients Undergoing Hemodialysis
Hospital de Clinicas de Porto Alegre
 2008-04 PHASE3
NCT00813774 COMPLETED
Bioavailability Study on Healthy Volunteers
UCB Pharma
 2008-02 PHASE1
NCT00900718 COMPLETED
Bone Loss
Institut Straumann AG
 2006-02
NCT01322464 COMPLETED
Food Effect
Jazz Pharmaceuticals
 2008-01 PHASE1
NCT00901017 COMPLETED
Jaw, Edentulous; Jaw, Edentulous, Partially
Institut Straumann AG
 2006-03
NCT00927342 COMPLETED
Thoracic Surgery; Air Leak
Royal Brompton & Harefield NHS Foundation Trust
 2005-12
NCT00356369 COMPLETED
Infections, Meningococcal
GlaxoSmithKline
 2006-12-23 PHASE2
NCT00504335 COMPLETED
Acute Radiation Syndrome
Humanetics Corporation
 2007-06 PHASE1
NCT00900822 COMPLETED
Jaw, Edentulous, Partially; Alveolar Bone Loss
Institut Straumann AG
 2005-11
NCT00328263 COMPLETED
Diarrhea; Clostridium Infections
Bio-K Plus International Inc.
 2006-03 PHASE3
NCT01561417 COMPLETED
Acquired Bleeding Disorder; Acquired Haemophilia; Congenital Bleeding Disorder; Congenital FVII Deficiency; Glanzmann's Disease; Haemophilia A With Inhibitors; Haemophilia B With Inhibitors; Healthy
Novo Nordisk A/S
 2006-04 PHASE1
NCT01554813 COMPLETED
Influenza
Hualan Biological Engineering, Inc.
 2006-05 PHASE3
NCT01661751 COMPLETED
Meningitis
Hualan Biological Engineering, Inc.
 2006-05 PHASE3
NCT00196924 COMPLETED
Infections, Papillomavirus
GlaxoSmithKline
 2004-06 PHASE3
NCT00864500 COMPLETED
Healthy
Actavis Inc.
 2005-11 PHASE1
NCT00169494 COMPLETED
Infections, Papillomavirus
GlaxoSmithKline
 2004-09 PHASE3
NCT00939536 COMPLETED
Healthy
Torrent Pharmaceuticals Limited
 2005-06 PHASE1
NCT00326781 COMPLETED
Smoking
University of Pennsylvania
 1999-12 PHASE4
NCT00879827 COMPLETED
Diphtheria; Poliomyelitis; Hepatitis B; Tetanus; Acellular Pertussis
GlaxoSmithKline
 2000-09 PHASE3
NCT00186563 COMPLETED
Skin Diseases
Martin Angst
NCT00322205 COMPLETED
Smoking Cessation
National Institutes of Health (NIH)
 1999-06 PHASE4
NCT00266292 UNKNOWN
Cardiovascular Heart Disease; Metabolic Syndrome
University of Copenhagen
 2005-09
NCT00145093 COMPLETED
Diabetes Mellitus, Type 2
Medical Research Foundation, The Netherlands
 2004-08 PHASE3
NCT00391417 COMPLETED
Hot Flashes
BioSante Pharmaceuticals
 2003-09 PHASE3
NCT00727818 COMPLETED
Bone Regeneration Following Wisdom Teeth Extraction
University of Zurich
 2006-05 PHASE4
NCT00463190 COMPLETED
Diarrhea; Enteritis; Enterocolitis
Chang Gung Memorial Hospital
 2006-02 PHASE4
NCT00345956 COMPLETED
Infections, Rotavirus
GlaxoSmithKline
 2006-09 PHASE3

(data from https://clinicaltrials.gov, updated on 2023-11-07)

Check the GSK-3 Inhibitor IX (BIO) product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Compliance for Clinical Use

Mechanism and Biochemical Profile

GSK-3 Inhibitor IX (BIO) selectively binds and inhibits glycogen synthase kinase-3 (GSK-3α/β) with an IC50 of 5 nM, thereby blocking downstream substrate phosphorylation and signaling cascades. This molecular inhibition induces apoptosis in human melanoma cells and suppresses aberrant cellular proliferation, providing a mechanistically relevant approach for oncological conditions such as locally advanced pancreatic cancer evaluated in clinical settings.

Appendix RUO and cGMP Quality Standards

Quality Dimension RUO (Research Use Only) cGMP (Current Good Manufacturing Practice)
Clinical Applicability Prohibited in human clinical trials or medical diagnostics. Mandatory for human clinical trials (Phase I–III) and therapies.
Regulatory Status Non-regulated grade; exempt from drug manufacturing laws. Legally enforced by health authorities (e.g., FDA, EMA, NMPA).
Facility Environment Unclassified analytical or research laboratories. Validated Cleanrooms (ISO Class 5–8) with continuous monitoring.
Quality Control Basic purity and activity testing. Rigorous safety release testing (Sterility, Endotoxin, Mycoplasma).
Process Validation Basic equipment calibration; no process validation required. Full qualification (IQ/OQ/PQ) and complete batch records.
Quality Assurance Vendor self-declared without required formal QMS. Mandatory QA/QC unit, Change Control, CAPA, and vendor audits.
Regulatory Impact High risk of IND rejection if used as a critical raw material. Required for IND/NDA filings, supported by Drug Master Files (DMF).

Footnotes

Regulatory Note: Governed by FDA (21 CFR Parts 210/211/312), EMA (EudraLex Vol 4), ICH Guidelines (E6/Q7/Q9/Q10), and compendial standards (USP <71>/<85>/<1043>).

Jump to

Note: Technical data last updated: Sep 1, 2026.