Cell-free Assays (IC50/Ki) for BGJ398 (Infigratinib)

Key TargetIC50 (Cell-free)DescriptionReference
No published data available.

Cell-based Assay (IC50) for BGJ398 (Infigratinib)

Cell TypeIC50 (Cell-based)DescriptionReference
OMUCR-1 cells 9.93 nM Cell Counting Kit-8 (CCK-8) assay Download PDF
NRH-LS1 cells 47 nM Cell viability was measured using the Luminescent Cell Viability Assay. Relative IC50 for 120 h was calculated using a four-parameter logistic function based on non-linear regression analysis using SigmaPlot. Download PDF
UPS cell lines (SHEF UPS01, SHEF UPS02, SHEF UPS03, SHEF UPS04, IEC-56) 0.632 lM (average), 0.022 –1.490 lM (range) PrestoBlue reagent reduction, Spark 20 M plate reader, Prism 10 software Download PDF
SNU-16 approximately 150 nM ATPlite assay Download PDF
KKU-213A 5.31 ±0.2 μM SRB assay PMC11126846
Check the BGJ398 (Infigratinib) product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

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