CAS No. 330942-05-7
Batch:
Purity:99.31
Chemical Structure
Check the
Betrixaban
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | N-(5-chloro-2-pyridinyl)-2-[[4-(N,N-dimethylcarbamimidoyl)benzoyl]amino]-5-methoxybenzamide | |
|---|---|---|
| CAS Number | 330942-05-7 | |
| Molecular Formula |
C23H22ClN5O3 |
|
| Molecular Weight (MW) | 451.91 | |
| SMILES | CN(C)C(=N)C1=CC=C(C=C1)C(=O)NC2=C(C=C(C=C2)OC)C(=O)NC3=NC=C(C=C3)Cl | |
| InChIKey | XHOLNRLADUSQLD-UHFFFAOYSA-N |
Betrixaban is a potent, oral, and selective direct Factor Xa inhibitor. By specifically targeting Factor Xa, it effectively blocks the assembly and catalytic activity of the prothrombinase complex, suppressing downstream thrombin generation and inhibiting blood coagulation pathways. These actions suppress thrombus formation and deliver effective antithrombotic activity in preclinical model systems.
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
35 mg/mL
(77.44 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.