CAS No. 222638-67-7
Batch:
Purity:99.89
Chemical Structure
Check the
BEC HCl
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | (2R)-2-amino-3-(2-boronoethylsulfanyl)propanoic acid;hydrochloride | |
|---|---|---|
| CAS Number | 222638-67-7 | |
| Molecular Formula |
C5H12BNO4S.HCl |
|
| Molecular Weight (MW) | 229.49 | |
| SMILES | B(CCSCC(C(=O)O)N)(O)O.Cl | |
| InChIKey | GHPYJLCQYMAXGG-WCCKRBBISA-N |
BEC HCl is a slow-binding, competitive arginase inhibitor targeting human arginase II at pH 7.5) and rat arginase I. By suppressing arginase-mediated L-arginine consumption, BEC elevates intracellular L-arginine levels available for nitric oxide synthase (NOS), downstream signaling, and nitric oxide generation, thereby modulating vascular tone and cellular immune phenotypes.
|
Concentration
Volume
Mass
|
1 mg | 5 mg | 10 mg |
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
45 mg/mL
(196.08 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 45 mg/mL |
| Ethanol | 45 mg/mL |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.