CAS No. 348086-71-5
Batch:
Purity:99.09
Chemical Structure
Check the
Pritelivir (BAY 57-1293)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | N-methyl-N-(4-methyl-5-sulfamoyl-1,3-thiazol-2-yl)-2-(4-pyridin-2-ylphenyl)acetamide | |
|---|---|---|
| CAS Number | 348086-71-5 | |
| Molecular Formula |
C18 H18 N4 O3 S2 |
|
| Molecular Weight (MW) | 402.49 | |
| SMILES | CC1=C(SC(=N1)N(C)C(=O)CC2=CC=C(C=C2)C3=CC=CC=N3)S(=O)(=O)N | |
| InChIKey | IVZKZONQVYTCKC-UHFFFAOYSA-N |
Pritelivir (BAY 57-1293) is a viral helicase-primase inhibitor that exhibits potent antiviral activity against herpes simplex virus 1 (HSV-1, and HSV-2. By target-specifically inhibiting the viral helicase-primase complex, it prevents viral DNA unwinding and synthesis during replication. This inhibition impairs viral DNA replication and blocks viral propagation in infected cells. [1]
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Concentration
Volume
Mass
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|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
80 mg/mL
(198.76 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
80 mg/mL
(198.76 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
- Pritelivir (BAY 57-1293) Clinical Trials
- Pritelivir (BAY 57-1293) Solubility in DMSO
- Pritelivir (BAY 57-1293) Stock Solution
- Pritelivir (BAY 57-1293) Storage
- Pritelivir (BAY 57-1293) Stability
- Pritelivir (BAY 57-1293) Molecular Weight
- Pritelivir (BAY 57-1293) SMILES
- Pritelivir (BAY 57-1293) Chemical Structure (2D and 3D)
- Pritelivir (BAY 57-1293) SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.