Molecular Weight: 484.94 g/mol
Chemical Structure
Check the
Sevabertinib (BAY 2927088)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
48 mg/mL
(98.98 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Chemical Information
| IUPAC Name | 3-(3-chloro-2-methoxyanilino)-2-[3-[[(2S)-1,4-dioxan-2-yl]methoxy]-4-pyridinyl]-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-one | |
|---|---|---|
| CAS Number | 2521285-05-0 | |
| Molecular Formula |
C24H25ClN4O5 |
|
| Molecular Weight (MW) | 484.94 | |
| InChIKey | VYQVHWNNPKOJEA-AWEZNQCLSA-N |
Jump to
- Sevabertinib (BAY 2927088) Clinical Trials
- Sevabertinib (BAY 2927088) Solubility in DMSO
- Sevabertinib (BAY 2927088) Stock Solution
- Sevabertinib (BAY 2927088) Storage
- Sevabertinib (BAY 2927088) Stability
- Sevabertinib (BAY 2927088) CAS Number
- Sevabertinib (BAY 2927088) Chemical Structure (2D and 3D)
- Sevabertinib (BAY 2927088) SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.