CAS No. 942437-37-8
Batch:
Purity:99.95
Chemical Structure
Check the
AZD7325
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 942437-37-8 | |
|---|---|---|
| Molecular Formula |
C19H19FN4O2 |
|
| Molecular Weight (MW) | 354.38 | |
| SMILES | CCCNC(=O)C1=NN=C2C(=C1N)C=CC=C2C3=C(C=CC=C3F)OC |
AZD7325 is an orally active, partial selective positive allosteric modulator of GABAA α2 and α3 receptor subtypes. By selectively potentiating GABA-mediated inhibitory neurotransmission through α2 and α3 subunit-containing GABAA receptors, AZD7325 modulates neural circuit activity and downstream signaling pathways, promoting anxiolytic functional phenotypes with reduced sedative side effects relative to non-selective benzodiazepine receptor agonists. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
71 mg/mL
(200.34 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 71 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.