CAS No. 29838-67-3
Batch:
Purity:99.84
Chemical Structure
Check the
Astilbin
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | (2R,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy-2,3-dihydrochromen-4-one | |
|---|---|---|
| CAS Number | 29838-67-3 | |
| Molecular Formula |
C21H22O11 |
|
| Molecular Weight (MW) | 450.39 | |
| SMILES | CC1C(C(C(C(O1)OC2C(OC3=CC(=CC(=C3C2=O)O)O)C4=CC(=C(C=C4)O)O)O)O)O | |
| InChIKey | ZROGCCBNZBKLEL-MPRHSVQHSA-N |
Astilbin is a naturally occurring flavonoid compound isolated from Smilax glabra Roxb that displays anti-inflammatory, immunosuppressive, and antioxidative activities. It suppresses T lymphocyte activation and selectively induces apoptosis in activated T cells by modulating the NF-kB and MAPK signaling pathways. This regulation decreases the secretion of proinflammatory mediators, including TNF-α and IL-6, thereby reducing cellular inflammatory and immune responses. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
90 mg/mL
(199.82 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| DMSO |
100 mg/mL
(222.02 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.