Molecular Weight: 448.88 g/mol

AST-1306 Chemical Structure
Chemical Structure
Check the AST-1306 product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 85 mg/mL (189.36 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water Insoluble
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

Chemical Information

IUPAC Name N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]quinazolin-6-yl]prop-2-enamide
CAS Number 897383-62-9
Molecular Formula

C24H18ClFN4O2
Molecular Weight (MW) 448.88
SMILES FC1=CC=CC(=C1)COC2=C(Cl)C=C(NC3=NC=NC4=C3C=C(NC(=O)C=C)C=C4)C=C2
InChIKey MVZGYPSXNDCANY-UHFFFAOYSA-N

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Note: Technical data last updated: Sep 1, 2026.