Clinical Trials

Aspirin is currently evaluated in numerous clinical trials spanning Early Phase 1 through Phase 4 protocols across cardiovascular, oncological, and inflammatory conditions, including colorectal neoplasia, blunt cerebrovascular injury, hepatocellular carcinoma, and coronary artery disease. Sponsored by major academic institutions and organizations such as the National Cancer Institute, Loma Linda University, and Fudan University, these studies encompass various recruitment stages, including completed, actively recruiting, and not yet recruiting.

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT07572747 NOT_YET_RECRUITING
Chronic Coronary Syndrome
Khalid F Alhabib
 2027-04-01 PHASE3
NCT07744191 NOT_YET_RECRUITING
Psoriasis (PsO); Psoriatic Arthritis (PsA)
NYU Langone Health
 2026-09 PHASE4
NCT06530537 RECRUITING
Cerebral Microbleeds; Stroke
Zhejiang Provincial People's Hospital
 2024-07-18 PHASE3
NCT07052799 RECRUITING
Myocardial Infarction (MI); Cardiovascular Events; Post Polypectomy Bleeding in Antiplatelet Patients
Chinese University of Hong Kong
 2026-02-10 PHASE3
NCT06494878 RECRUITING
Venous Thromboembolism; Postpartum Period; Aspirin; Low Molecular Weight Heparin
University of Calgary
 2026-06-04 PHASE3
NCT07762703 NOT_YET_RECRUITING
Triple-Negative Breast Cancer (TNBC)
BreakBio Corp
 2026-09 PHASE1; PHASE2
NCT06650488 RECRUITING
Staphylococcus Aureus Endocarditis; Staphylococcus Aureus Septicemia; Staphylococcus Aureus Bloodstream Infection
Todd C. Lee MD MPH FIDSA
 2026-01-15 PHASE4
NCT05462613 RECRUITING
Metastatic Colorectal Cancer
Centre Hospitalier Universitaire de Besancon
 2023-05-09 PHASE2; PHASE3
NCT07795398 NOT_YET_RECRUITING
Ischemic Heart Disease; Ischemic Heart Disease Chronic; Chronic Coronary Syndrome; Myocardial Infarction; Percutaneous Coronary Intervention; Coronary Artery Bypass Graft; Aspirin; Aspirin Causing Adverse Effects in Therapeutic Use; Non-inferiority Trial
Odense University Hospital
 2026-09-14 PHASE4
NCT06866964 RECRUITING
Germ Cell Tumor; Testicular Cancer
Wake Forest University Health Sciences
 2025-08-28 PHASE2
NCT06763744 NOT_YET_RECRUITING
Acute Coronary Syndrome (ACS) Undergoing Percutaneous Coronary Intervention (PCI); High Bleeding Risk
Samsung Medical Center
 2025-06-01 PHASE4
NCT07736196 NOT_YET_RECRUITING
Acute Coronary Syndrome (ACS) Undergoing Percutaneous Coronary Intervention (PCI); Dual Anti-platelet Therapy
Assiut University
 2026-07-15 PHASE4
NCT06826859 RECRUITING
Preterm Birth; Preeclampsia
Thomas Jefferson University
 2025-06-26 PHASE1; PHASE2
NCT07677410 RECRUITING
Aortic Regurgitation Disease
Shanghai Zhongshan Hospital
 2026-07-18
NCT07113158 NOT_YET_RECRUITING
Sudden Sensorineural Hearing Loss
Assistance Publique - Hôpitaux de Paris
 2026-04-01 PHASE3
NCT04356326 RECRUITING
Chronic Hypertension Complicating Pregnancy; Pre-Eclampsia; Intrauterine Growth Restriction; Aspirin; Perinatal Death; Placental Abruption
Centre Hospitalier Intercommunal Creteil
 2021-02-15 PHASE3
NCT06451198 RECRUITING
Coronary Artery Disease; Antiplatelet Drugs
Shanghai Zhongshan Hospital
 2025-05-19 PHASE4
NCT07760922 NOT_YET_RECRUITING
Ischemic Stroke, Acute
Xinqiao Hospital of Chongqing
 2026-10-01 PHASE4
NCT06980025 RECRUITING
Preterm Delivery; Obstetrical Complications
The George Washington University Biostatistics Center
 2025-07-01 PHASE3
NCT06935994 RECRUITING
Metabolic Dysfunction Associated Steatotic Liver Disease
Taichung Veterans General Hospital
 2025-05-05 PHASE2
NCT04381936 RECRUITING
Pneumonia
University of Oxford
 2020-03-19 PHASE3
NCT05353140 RECRUITING
Atrial Fibrillation; Percutaneous Coronary Intervention
Xijing Hospital
 2022-09-01
NCT05625724 RECRUITING
ART; Pre-Eclampsia
University Hospital, Toulouse
 2023-08-02 PHASE3
NCT06952712 NOT_YET_RECRUITING
Preeclampsia
FANG HE
 2025-05-07 PHASE3
NCT07665853 NOT_YET_RECRUITING
Preeclampsia
Hospital Universitari Vall d'Hebron Research Institute
 2026-07-01 PHASE3
NCT03590821 NOT_YET_RECRUITING
Healthy
University of Pennsylvania
 2027-12 EARLY_PHASE1
NCT06738992 RECRUITING
Mitral Valve Repair Surgery
Guangdong Provincial People's Hospital
 2024-11-14 PHASE4
NCT05955365 RECRUITING
Percutaneous Coronary Intervention (PCI); Atrial Fibrillation (AF); Oral Anticoagulation; P2Y12 Inhibitor
Insel Gruppe AG, University Hospital Bern
 2023-12-18 PHASE4
NCT07540416 NOT_YET_RECRUITING
Acute Ischemic Stroke
The First Affiliated Hospital of Zhengzhou University
 2026-05-01 PHASE3
NCT03244020 ENROLLING_BY_INVITATION
Sarcoma; Soft Tissue Sarcoma; Bone Sarcoma; Bone Metastases; Venous Thromboembolism; Hematoma; Anticoagulant-induced Bleeding
Massachusetts General Hospital
 2018-02-16 PHASE4
NCT01731236 ACTIVE_NOT_RECRUITING
Dietary Modification
The Cleveland Clinic
 2011-02-11 EARLY_PHASE1
NCT06937372 NOT_YET_RECRUITING
Hip Fractures; Venous Thromboembolism (VTE)
Queen Mary University of London
 2026-08-01
NCT07686770 NOT_YET_RECRUITING
Kawasaki Disease
Children's Hospital of Fudan University
 2026-08-01 PHASE2; PHASE3
NCT06580223 NOT_YET_RECRUITING
Multiple Myeloma; Venous Thromboembolism
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
 2025-09-01 PHASE3
NCT05476991 RECRUITING
Stroke; Stroke, Ischemic; Atherosclerosis; Myocardial Infarction; Coronary Syndrome; TIA; Cardiac Disease; Cerebral Infarction
Assistance Publique - Hôpitaux de Paris
 2023-05-17 PHASE3
NCT02497820 NOT_YET_RECRUITING
Lynch Syndrome I (Site-specific Colonic Cancer)
Tel-Aviv Sourasky Medical Center
 2016-09 PHASE3
NCT07796217 RECRUITING
Cardiac Event; Coronary Artery Disease; Peripheral Artery Disease; Bleeding
Seoul National University Bundang Hospital
 2023-11-15 PHASE4
NCT04014803 RECRUITING
Coronary Artery Disease
Samsung Medical Center
 2020-01-13 PHASE4
NCT05702463 RECRUITING
Platelet Aggregation; Type 2 Diabetes; Aspirin; Diabetes Mellitus, Type 2; Platelet Aggregation Inhibitors
Montreal Heart Institute
 2023-06-13 PHASE1
NCT04796714 RECRUITING
Atrial Fibrillation; Atrial Appendage; Anticoagulants; Stroke; Platelet Aggregation Inhibitors
University Hospital, Bordeaux
 2022-10-03 PHASE4
NCT07524335 NOT_YET_RECRUITING
Coronary Artery Disease; Subclinical Atherosclerotic Cardiovascular Disease
Montreal Heart Institute
 2026-05-01 PHASE3
NCT03899987 ACTIVE_NOT_RECRUITING
Prostate Adenocarcinoma; Stage I Prostate Cancer AJCC v8; Stage II Prostate Cancer AJCC v8; Stage IIA Prostate Cancer AJCC v8; Stage IIB Prostate Cancer AJCC v8; Stage IIC Prostate Cancer AJCC v8; Stage III Prostate Cancer AJCC v8; Stage IIIA Prostate Cancer AJCC v8; Stage IIIB Prostate Cancer AJCC v8; Stage IIIC Prostate Cancer AJCC v8
Roswell Park Cancer Institute
 2019-11-29 PHASE2
NCT07523841 ACTIVE_NOT_RECRUITING
Periodontitis; Periodontitis (Stage 3)
Hanoi Medical University
 2023-04-01
NCT06175377 NOT_YET_RECRUITING
Chronic Total Occlusion
Assistance Publique Hopitaux De Marseille
 2024-03-30
NCT06723145 RECRUITING
Antiplatelet Agents; Perioperative Care
Kyoto University
 2025-01-20 PHASE4
NCT07745595 NOT_YET_RECRUITING
Preterm Labor; Premature Birth
University of Health Sciences Lahore
 2026-08-20
NCT05557877 RECRUITING
Breast Carcinoma
Mayo Clinic
 2023-03-09 PHASE2
NCT04694248 RECRUITING
Deep Vein Thrombosis; Iliac Vein Thrombosis; Iliac Vein Obstruction; Iliac Vein Stenosis; Iliac Vein Compression Syndrome
First Affiliated Hospital of Zhejiang University
 2021-11-03
NCT05681702 RECRUITING
Coronary Artery Disease
University of Florida
 2023-02-15 PHASE4
NCT04308551 WITHDRAWN
Stable Coronary Heart Disease
Henan Institute of Cardiovascular Epidemiology
 2024-12-30
NCT05924971 RECRUITING
Preeclampsia Postpartum
MemorialCare Health System
 2023-07-26 PHASE2
NCT05638867 RECRUITING
Coronary Artery Disease; Percutaneous Coronary Intervention; Acute Coronary Syndrome
China National Center for Cardiovascular Diseases
 2023-11-25 PHASE4
NCT06756945 NOT_YET_RECRUITING
ST-elevation Myocardial Infarction (STEMI)
Beijing Anzhen Hospital
 2025-01 PHASE4
NCT05411718 RECRUITING
T Cells; Colorectal Cancer; Lynch Syndrome
M.D. Anderson Cancer Center
 2023-03-21 PHASE2
NCT07652723 RECRUITING
Drug-drug Interaction
Bayer
 2026-05-29 PHASE1
NCT06090890 RECRUITING
In-stent Restenosis
Fu Wai Hospital, Beijing, China
 2023-10-30 PHASE4
NCT02804815 ACTIVE_NOT_RECRUITING
Cancer; Breast Cancer; Prostate Cancer; Colorectal Cancer; Gastro-oesophageal Cancer
University College, London
 2015-10 PHASE3
NCT04145258 RECRUITING
Tuberculous Meningitis
ANRS, Emerging Infectious Diseases
 2021-02-07 PHASE3
NCT07361679 RECRUITING
Preeclampsia Severe; Toxemia Of Pregnancy; Preeclampsia; Pregnancy Complications; Hypertension, Pregnancy-Induced; Gestational Hypertension
Alexandra Hospital, Athens, Greece
 2023-01-18 PHASE4
NCT06486363 NOT_YET_RECRUITING
Intracranial Aneurysms; Antiplatelet Drugs
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
 2024-08-01 PHASE4
NCT07169513 NOT_YET_RECRUITING
Peripheral Arterial Disease; Silent Atherosclerosis
Guy's and St Thomas' NHS Foundation Trust
 2025-10-01
NCT05080946 RECRUITING
Ovarian Cancer; Fallopian Tube Cancer; Peritoneal Cancer
H. Lee Moffitt Cancer Center and Research Institute
 2021-11-02 EARLY_PHASE1
NCT05612984 WITHDRAWN
Preterm Labor; Small for Gestational Age at Delivery; Hypertensive Disorder of Pregnancy; Low Birth Weight; Neonatal Death
Johns Hopkins Bloomberg School of Public Health
 2024-04-01 PHASE3
NCT03378934 RECRUITING
Coronary Artery Disease; Percutaneous Coronary Intervention
Peking Union Medical College Hospital
 2018-09-26 PHASE4
NCT04698031 ACTIVE_NOT_RECRUITING
Silent Brain Infarction
VA Office of Research and Development
 2022-03-30 PHASE4
NCT05575037 ACTIVE_NOT_RECRUITING
Nasal Polyps; Asthma, Aspirin-Induced; Aspirin-Exacerbated Respiratory Disease; Aspirin-Sensitive Asthma With Nasal Polyps
Brigham and Women's Hospital
 2023-08-01 PHASE2
NCT07265466 RECRUITING
Drug Drug Interaction (DDI)
Onconic Therapeutics Inc.
 2025-11-17 PHASE1
NCT06018688 UNKNOWN
Non Small Cell Lung Cancer; EGFR Gene Mutation
Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
 2023-09-15 PHASE2
NCT06548971 RECRUITING
Acute Ischemic Stroke; Cerebral Infarction
Capital Medical University
 2024-11-07 PHASE3
NCT06037889 COMPLETED
Branch Atheromatous Disease
Peking Union Medical College Hospital
 2023-11-09 PHASE3
NCT06378398 COMPLETED
Colorectal Neoplasia
University of Michigan Rogel Cancer Center
 2024-06-14 EARLY_PHASE1
NCT07597239 ACTIVE_NOT_RECRUITING
Thrombosis; Arterial Occlusive Diseases; Thromboelastography (TEG); Peripheral Arterial Disease(PAD); Stent Thrombosis; Platelet Inhibition; PRU(Platelet Reactivity Unit)
Massachusetts General Hospital
 2020-11-01
NCT04147013 ACTIVE_NOT_RECRUITING
Chronic Rhinosinusitis with Nasal Polyps; Aspirin-exacerbated Respiratory Disease
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
 2020-02-18 PHASE4
NCT05986968 ACTIVE_NOT_RECRUITING
ST Elevation Myocardial Infarction
Radboud University Medical Center
 2023-07-06
NCT06613191 NOT_YET_RECRUITING
Coronary Arterial Disease (CAD); Peripheral Vascular Disease
Ochsner Health System
 2024-10-01 PHASE4
NCT06316570 COMPLETED
Ischemic Stroke, Acute
Beijing Tiantan Hospital
 2024-04-03 PHASE3
NCT04624295 RECRUITING
Antiplatelet Therapy; Hemorrhagic Infarction
Second Affiliated Hospital, Zhejiang University, School of Medicine
 2021-01-01 PHASE4
NCT03377543 ACTIVE_NOT_RECRUITING
Inflammatory Response; Inflammation; Sleep; Sleep Restriction
Beth Israel Deaconess Medical Center
 2018-06-06 EARLY_PHASE1
NCT05257824 COMPLETED
Aneurysm Cerebral; Endovascular Procedures
Seoul National University Bundang Hospital
 2022-06-23 PHASE4
NCT06238115 COMPLETED
Unruptured Intracranial Aneurysm; Flow Diverter; Stent-assisted Coiling; Thromboembolic Events
Beijing Tiantan Hospital
 2024-03-04 PHASE2; PHASE3
NCT06053021 UNKNOWN
Acute Ischemic Stroke; Thrombocytopenia
Second Affiliated Hospital, Zhejiang University, School of Medicine
 2023-09-15
NCT04624854 COMPLETED
Coronary Artery Disease; Myocardial Ischemia; Acute Coronary Syndrome; Heart Diseases; Syndrome Heart Disease; Cardiovascular Diseases; Arteriosclerosis; Arterial Occlusive Diseases; Coronary Disease; Vascular Diseases
Harbin Medical University
 2020-10-28 PHASE4
NCT07117903 RECRUITING
Platelet Function and Thrombus Formation
Fudan University
 2025-08-10
NCT04379999 COMPLETED
Lynch Syndrome
Fox Chase Cancer Center
 2018-09-10 EARLY_PHASE1
NCT03568890 ACTIVE_NOT_RECRUITING
Left Atrial Appendage Closure; Thrombosis; Stroke; TIA; Bleeding
Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Quebec
 2018-09-01 PHASE4
NCT05907902 UNKNOWN
Intracranial Aneurysm; Cerebrovascular Disease
Beijing Tiantan Hospital
 2023-07-01 PHASE3
NCT05009862 COMPLETED
Peripheral Arterial Disease
Vanderbilt University Medical Center
 2022-04-19 PHASE4
NCT05278182 UNKNOWN
Atherosclerotic Cardiovascular Disease
Chinese Academy of Medical Sciences, Fuwai Hospital
 2022-12
NCT05104229 WITHDRAWN
Crohn Disease; Ulcerative Colitis; Venous Thromboembolism
Stefan Holubar MD MS FACS, FASCRS
 2024-06-01 PHASE3
NCT04075240 COMPLETED
Venous Thromboembolism
Sudeep Shivakumar
 2021-02-04 PHASE3
NCT06444178 COMPLETED
Healthy Volunteers
Regeneron Pharmaceuticals
 2024-09-30 PHASE1
NCT05546320 COMPLETED
Patent Foramen Ovale; Migraine
Chinese Academy of Medical Sciences, Fuwai Hospital
 2022-10-15 PHASE2
NCT03978988 ACTIVE_NOT_RECRUITING
Carotid Artery Diseases; Thrombectomy; Tandem Occlusion; Stroke
Central Hospital, Nancy, France
 2020-04-29
NCT07087067 COMPLETED
Preeclampsia; Pregnancy
Galala University
 2023-02-05
NCT05718531 UNKNOWN
Coronary Artery Ectasia
Assiut University
 2023-02-01 PHASE3
NCT07444164 COMPLETED
Healthy
Laboratorios Silanes S.A. de C.V.
 2025-01-13 PHASE1
NCT05709626 RECRUITING
ST-segment Elevation Myocardial Infarction (STEMI)
Kindai University
 2023-02-28 PHASE4
NCT07622056 COMPLETED
Chronic Coronary Syndrome; Coronary Artery Disease; Percutaneous Coronary Intervention
Kaohsiung Veterans General Hospital.
 2024-01-03 PHASE4
NCT04850417 NOT_YET_RECRUITING
Spontaneous Coronary Artery Dissection
Spanish Society of Cardiology
 2021-04-30 PHASE4
NCT06111079 UNKNOWN
Preeclampsia; Perinatal Haemorrhage
FANG HE
 2023-11-01 PHASE3
NCT06133803 UNKNOWN
Infertility, Female
Fertility Center of Las Vegas
 2024-01-26 PHASE4
NCT06088433 UNKNOWN
Coronary Heart Disease
Fu Wai Hospital, Beijing, China
 2023-11-15 PHASE4
NCT05056896 ACTIVE_NOT_RECRUITING
Colorectal Cancer
Massachusetts General Hospital
 2022-06-03 EARLY_PHASE1
NCT05797376 COMPLETED
Atherosclerosis of Artery; Coronary Artery Disease; Peripheral Arterial Disease; Carotid Stenosis
Asan Medical Center
 2021-08-24 PHASE4
NCT04418479 COMPLETED
Coronary Artery Disease
Joo-Yong Hahn
 2020-08-10 PHASE4
NCT05193071 COMPLETED
Ischemic Stroke
General Hospital of Shenyang Military Region
 2022-07-08 PHASE4
NCT03290820 UNKNOWN
Nasopharyngeal Carcinoma
Sun Yat-sen University
 2018-01-01 PHASE2
NCT06591390 RECRUITING
Ischemic Stroke
Kafrelsheikh University
 2022-02-09 PHASE3
NCT06591312 RECRUITING
Ischemic Stroke
Kafrelsheikh University
 2022-05-01 PHASE3
NCT05960864 Not yet recruiting
Ankylosing Spondylitis (AS) / Radiographic Axial SpA (r-axSpA)|Non-radiographic Axial Spondyloarthritis (Nr-axSpA)|Axial Psoriatic Arthritis (axPsA)|Acute Anterior Uveitis (AAU)|Crohn Disease (CD)|Ulcerative Colitis (UC)|Reactive Arthritis (ReA)
Southwest Hospital China
 2024-09 --
NCT06002490 COMPLETED
Polycythemia Vera (PV)
PharmaEssentia Japan K.K.
 2023-10-17 PHASE3
NCT02520921 COMPLETED
Diabetes Mellitus; Acute Coronary Syndrome; Coronary Artery Disease; Obesity
Assistance Publique - Hôpitaux de Paris
 2016-06-13 PHASE4
NCT05868525 Recruiting
Blunt Cerebrovascular Injury
Loma Linda University
 2024-07 Phase 4
NCT06197009 Not yet recruiting
Axial Spondyloarthritis
Sinocelltech Ltd.
 2024-07-01 Phase 2
NCT07378228 COMPLETED
Coronary Heart Disease; Stable Angina Pectoris
Xikun Li
 2023-07-01
NCT01650792 UNKNOWN
Chagas Disease With Heart Failure
Federal University of Bahia
 2012-07 PHASE4
NCT00565708 UNKNOWN
Colorectal Cancer
National Cancer Centre, Singapore
 2008-12 PHASE3
NCT06378398 Not yet recruiting
Colorectal Neoplasia
University of Michigan Rogel Cancer Center|National Cancer Institute (NCI)
 2024-05 Early Phase 1
NCT05105919 ACTIVE_NOT_RECRUITING
Diabetes Mellitus, Type 2
Montreal Heart Institute
 2021-08-26 EARLY_PHASE1
NCT03047837 TERMINATED
Tertiary Prevention in Colon Cancer
Ente Ospedaliero Ospedali Galliera
 2017-03-15 PHASE2
NCT04070573 COMPLETED
Preeclampsia
Weill Medical College of Cornell University
 2019-10-21 PHASE3
NCT02604732 UNKNOWN
Inguinal Hernia
National University Hospital, Singapore
 2016-04-01
NCT04645550 COMPLETED
Cirrhosis; Splenectomy; Status; Venous Thrombosis; Hypertension, Portal
Northern Jiangsu People's Hospital
 2020-11-22 PHASE4
NCT05554822 UNKNOWN
Left Atrial Appendage Occlusion; Antiplatelet Therapy
Azienda Ospedaliero Universitaria Maggiore della Carita
 2021-06-14 PHASE3
NCT03232450 WITHDRAWN
Foramen Ovale, Patent
Mayo Clinic
 2019-08
NCT05663307 UNKNOWN
Ischemic Stroke, Acute
Shanghai Yueyang Integrated Medicine Hospital
 2021-01-01 PHASE2; PHASE3
NCT04243122 COMPLETED
Myeloproliferative Neoplasm (MPN); Essential Thrombocythemia (ET); JAK2 Mutation; Polycythemia Vera (PV); Primary Myelofibrosis; Venous Thromboembolism (VTE)
Ottawa Hospital Research Institute
 2021-02-17 PHASE2
NCT03728179 COMPLETED
Solid Tumor, Adult
Centre Hospitalier Universitaire Vaudois
 2019-01-16 PHASE1
NCT04738097 COMPLETED
Ischemic Stroke; Transient Ischemic Attack
Mazandaran University of Medical Sciences
 2021-08-08 PHASE3
NCT04516993 COMPLETED
Stroke
Huashan Hospital
 2021-09-28 PHASE2
NCT02467582 TERMINATED
Colon Cancer
Swiss Cancer Institute
 2016-06-09 PHASE3
NCT04456608 TERMINATED
Platelet Function
University of Washington
 2016-08-01 PHASE4
NCT03557242 UNKNOWN
Aortic Stenosis
Medstar Health Research Institute
 2018-07-05
NCT05625347 TERMINATED
Obstructive Pulmonary Function; Restrictive Pulmonary Function
Vectura, Inc.
 2023-03-11 PHASE1
NCT05709509 UNKNOWN
ST Elevation Myocardial Infarction; Colchicine; Cardiac Remodeling, Ventricular
RSD dr. Soebandi
 2022-06-01 PHASE4
NCT05308030 UNKNOWN
Peripheral Arterial Disease
Assiut University
 2022-08-01 EARLY_PHASE1
NCT04038489 WITHDRAWN
Breast Cancer; Estrogen Receptor-positive Breast Cancer
University of Virginia
 2019-10-18 PHASE2
NCT03028350 COMPLETED
Asthma, Aspirin-Induced
Cumberland Pharmaceuticals
 2017-07-17 PHASE2
NCT03961360 COMPLETED
Pre-Eclampsia; Hypertension in Pregnancy; Obesity
The University of Texas Health Science Center, Houston
 2019-05-06 PHASE2; PHASE3
NCT04273516 COMPLETED
Stroke; Prevention
Mazandaran University of Medical Sciences
 2020-08-22 PHASE2; PHASE3
NCT06106880 COMPLETED
Common Cold; Pharyngitis; Fever; Congestion; Rhinorrhea; Cough; Sore-throat; Sore Throats Viral; Malaise; Headache; Runny Nose; Sneezing
Applied Biological Laboratories Inc
 2022-05-25 PHASE1
NCT03192215 TERMINATED
Stroke
Columbia University
 2018-01-19 PHASE3
NCT04228263 COMPLETED
Unexplained Recurrent Miscarriage
Assiut University
 2020-01-01
NCT05998421 COMPLETED
Acupuncture; Recurrent Spontaneous Abortion; Ultrasound Therapy; Coagulation
Jianmei Xia
 2022-03-01
NCT04661709 UNKNOWN
Coronary Heart Disease; Unstable Angina; Chinese Herbal Medicine
Guang'anmen Hospital of China Academy of Chinese Medical Sciences
 2021-03-01 PHASE4
NCT04031729 COMPLETED
Nonalcoholic Fatty Liver; Nonalcoholic Steatohepatitis
Massachusetts General Hospital
 2019-09-12 PHASE1; PHASE2
NCT02965703 ACTIVE_NOT_RECRUITING
Colorectal Adenoma; Colorectal Carcinoma
National Cancer Institute (NCI)
 2018-01-16 PHASE2
NCT03735433 TERMINATED
Preeclampsia
Ohio State University
 2019-01-15 PHASE4
NCT04243278 TERMINATED
Preeclampsia Severe; Cardiovascular Diseases; Primary Prevention
Dr. Graeme Smith
 2020-09-14 EARLY_PHASE1
NCT04744571 UNKNOWN
Coronary Artery Disease; Coronary Occlusion; Percutaneous Coronary Intervention; Chronic Total Occlusion of Coronary Artery; Drug-Eluting Stents
Beijing Anzhen Hospital
 2021-02
NCT02974920 UNKNOWN
Aortic Stenosis; Aortic Regurgitation; Thrombosis
Christian Torp-Pedersen
 2017-01-01 PHASE4
NCT05343429 UNKNOWN
Sore Throat
Rehman Medical Institute - RMI
 2022-04-01 PHASE4
NCT06522113 COMPLETED
Ischemic Stroke; TIA
Incheon St.Mary's Hospital
 2019-07-18 PHASE4
NCT02144064 UNKNOWN
Recurrent Pregnancy Loss
Benha University
 2019-06-23 PHASE3
NCT01659307 COMPLETED
Acute Lung Injury
Belfast Health and Social Care Trust
 2012-09 PHASE2
NCT02832544 COMPLETED
Rheumatic Heart Disease
Population Health Research Institute
 2016-08-22 PHASE3
NCT03893630 COMPLETED
Pre-Eclampsia
John O'Brien, MD
 2019-04-25 PHASE2
NCT03661411 COMPLETED
Stroke
General Hospital of Shenyang Military Region
 2018-10-17 PHASE4
NCT05221164 UNKNOWN
Preeclampsia
Methodist Medical Center of Illinois
 2021-07-06 PHASE4
NCT04797949 WITHDRAWN
Medication Adherence; Preeclampsia
Women and Infants Hospital of Rhode Island
 2021-03-03 PHASE4
NCT06019741 COMPLETED
Post Coronary Bypass Surgery Patients
Shiraz University of Medical Sciences
 2021-02-01 PHASE4
NCT03766581 COMPLETED
Acute Ischemic Stroke; Transient Ischemic Attack (TIA)
Bristol-Myers Squibb
 2019-01-27 PHASE2
NCT03326063 COMPLETED
Nasal Polyps; Asthma, Aspirin-Induced; Aspirin-exacerbated Respiratory Disease; Aspirin-Sensitive Asthma With Nasal Polyps
Brigham and Women's Hospital
 2018-04-26 PHASE2
NCT05105750 UNKNOWN
Coronary Atherosclerosis
The First Affiliated Hospital with Nanjing Medical University
 2021-10-15 PHASE4
NCT03447379 COMPLETED
Coronary Artery Disease
Gangnam Severance Hospital
 2017-12-15
NCT04352439 COMPLETED
Venous Thromboembolism; Ovarian Cancer
Duke University
 2020-08-08 PHASE4
NCT03824938 COMPLETED
Multiple Sclerosis
Columbia University
 2019-04-30 PHASE3
NCT04504864 UNKNOWN
Ischemic Stroke
Xijing Hospital
 2020-10-01 PHASE4
NCT04083950 ACTIVE_NOT_RECRUITING
Intestinal Permeability; Inflammation; Vaccine; Typhoid Fever
USDA, Western Human Nutrition Research Center
 2019-12-04 EARLY_PHASE1
NCT03433586 UNKNOWN
Cardiovascular Diseases
Brigham and Women's Hospital
 2020-07-10 PHASE4
NCT05515120 COMPLETED
Venous Thromboembolism; Anticoagulant-induced Bleeding; Venous Thromboses; Pulmonary Embolism
Instituto Mexicano del Seguro Social
 2021-01-03 PHASE2; PHASE3
NCT02927249 TERMINATED
Node Positive HER2 Negative Breast Cancer
Alliance for Clinical Trials in Oncology
 2017-01-06 PHASE3
NCT04260828 UNKNOWN
Renal Transplant
Henan Provincial People's Hospital
 2020-02-28 PHASE4
NCT01936233 UNKNOWN
Hepatocellular Carcinoma; Recurrence
Fudan University
 2013-08 PHASE3
NCT04860804 COMPLETED
Pain
Antonios Likourezos
 2021-04-22 PHASE4
NCT05775536 COMPLETED
Dry Eye
Medical University of Vienna
 2021-01-21 PHASE2
NCT04333407 TERMINATED
COVID-19
Imperial College London
 2020-04-03
NCT04158830 WITHDRAWN
Preeclampsia
University of Tennessee
 2020-06-01 PHASE4
NCT04410328 COMPLETED
Covid19
Rutgers, The State University of New Jersey
 2020-10-21 PHASE3
NCT03583229 UNKNOWN
Coronary Artery Disease in Transplanted Heart (Diagnosis); Platelet Dysfunction
Aarhus University Hospital
 2016-10-13
NCT03357367 COMPLETED
Peripheral Arterial Disease
University Hospital, Angers
 2018-02-08
NCT04256525 UNKNOWN
Venous Thrombosis Due to Central Venous Access Device (Disorder); Prophylactic Anticoagulation; Patients With Tumor
Second Affiliated Hospital, Zhejiang University, School of Medicine
 2020-05-01 PHASE4
NCT04498273 TERMINATED
COVID-19
Frank C Sciurba
 2020-09-07 PHASE3
NCT04768179 UNKNOWN
Covid19
Makerere University
 2021-02-19 PHASE2; PHASE3
NCT03192059 COMPLETED
Cervical Cancer; Endometrial Cancer; Uterine Cancer
University Hospital, Ghent
 2017-07-01 PHASE2
NCT04338919 UNKNOWN
Acute Coronary Syndrome; Percutaneous Coronary Intervention
Fujian Medical University
 2020-04-14
NCT04182100 COMPLETED
Polycythemia Vera (PV)
PharmaEssentia Japan K.K.
 2019-12-20 PHASE2
NCT02044250 COMPLETED
Coronary Heart Disease
Seoul National University Hospital
 2014-02 PHASE4
NCT04059679 UNKNOWN
Coronary Artery Disease; Peripheral Artery Disease
LifeBridge Health
 2020-01-30 PHASE4
NCT03581409 COMPLETED
Aneurysm, Cerebral; Endovascular Procedures
Seoul National University Hospital
 2018-10-24 PHASE4
NCT03620760 UNKNOWN
Unstable Angina Pectoris; Coronary Stent Implantation
Xiaofan Wu
 2018-08-07 PHASE4
NCT03794336 COMPLETED
Type 2 Diabetes Mellitus
Sanofi
 2019-06-29 PHASE4
NCT03726177 UNKNOWN
Preeclampsia
Aswan University Hospital
 2018-12-01
NCT03279809 TERMINATED
Biliary Stasis, Extrahepatic
Woo Hyun Paik
 2017-10-12
NCT03198741 COMPLETED
Gastrointestinal Injury; Ischemic Heart Disease
Shenyang Northern Hospital
 2017-07-13 PHASE4
NCT02053909 COMPLETED
Saphenous Vein Graft Disease
Boca Raton Regional Hospital
 2014-09 PHASE4
NCT04425590 UNKNOWN
Ischemic Stroke
Duta Wacana Christian University
 2020-04-01 PHASE2; PHASE3
NCT03989557 COMPLETED
Unruptured Intracranial Aneurysm; Stents; Antiplatelet Drugs
Beijing Neurosurgical Institute
 2019-07-01 PHASE4
NCT02675205 COMPLETED
Cerebral Aneurysm
Fondation Ophtalmologique Adolphe de Rothschild
 2015-12 PHASE3
NCT04051567 UNKNOWN
Twin Pregnancy; Preeclampsia; Preterm Birth; Fetal Growth Restriction
Ministry of Science and Technology of the People´s Republic of China
 2018-11-01 PHASE4
NCT03112707 UNKNOWN
Coronary Artery Disease; Acute Coronary Syndrome
Humanitas Hospital, Italy
 2017-04-14 PHASE4
NCT02666742 COMPLETED
Ventricular Tachycardia; Premature Ventricular Contraction; Stroke
Kansas City Heart Rhythm Institute
 2017-02-16 PHASE4
NCT03900871 UNKNOWN
Aspirin as an Adjuvant Therapy, to Observe Its Effect on the Disease Free Survival Rate of Patients With Esophageal Squamous Cell Carcinoma
Hebei Medical University Fourth Hospital
 2019-04-10 EARLY_PHASE1
NCT03396952 COMPLETED
Stage III Cutaneous Melanoma; Stage IIIA Cutaneous Melanoma; Stage IIIB Cutaneous Melanoma; Stage IIIC Cutaneous Melanoma; Stage IV Cutaneous Melanoma
University of California, San Francisco
 2018-04-19 PHASE2
NCT02607917 COMPLETED
Myocardial Infarction; Stroke
University of Minnesota
 2015-02-16
NCT03170115 TERMINATED
Rectal Cancer, Adenocarcinoma; Locally Advanced Malignant Neoplasm; Chemoradiation
Instituto Nacional de Cancer, Brazil
 2017-11-30 PHASE2
NCT03491410 UNKNOWN
Breast Cancer
Centro Hospitalar Lisboa Ocidental
 2018-06-01 PHASE2; PHASE3
NCT02966119 TERMINATED
Cerebral Hemorrhage
University Hospital, Lille
 2016-12-07 PHASE3
NCT03765619 COMPLETED
Ankle Fractures
University of Alabama at Birmingham
 2019-06-12 EARLY_PHASE1
NCT03844191 COMPLETED
Coronary Disease
CeleCor Therapeutics
 2019-02-18 PHASE1
NCT02975076 UNKNOWN
Stroke, Acute; Ischemic Attack, Transient
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
 2016-12
NCT02986594 UNKNOWN
Thrombophilia With Recurrent Pregnancy Loss
Shanghai First Maternity and Infant Hospital
 2016-11 PHASE4
NCT02807441 WITHDRAWN
Hemorrhage; Thrombosis
University Hospitals Cleveland Medical Center
 2016-07 PHASE3
NCT02521285 ACTIVE_NOT_RECRUITING
Barrett Esophagus; Esophageal Adenocarcinoma
National Cancer Institute (NCI)
 2016-01-15 PHASE2
NCT02394769 ACTIVE_NOT_RECRUITING
Colorectal Cancer
Massachusetts General Hospital
 2015-07-06
NCT03244267 COMPLETED
Thromboembolic Event
Emory University
 2017-10-03
NCT02744937 UNKNOWN
Complication
National Taiwan University Hospital
 2016-04 PHASE4
NCT04062032 COMPLETED
Melanoma (Skin)
University of Utah
 2016-09-27 PHASE2
NCT02348203 COMPLETED
Tobacco Use Disorder
National Cancer Institute (NCI)
 2016-01-13 PHASE2
NCT03698513 COMPLETED
Healthy Volunteers
Bristol-Myers Squibb
 2018-10-04 PHASE1
NCT02776540 COMPLETED
Ischemic Cerebrovascular Accident
Ain Shams University
 2016-06-01 PHASE4
NCT02797249 COMPLETED
Preeclampsia
Peking University First Hospital
 2016-12-07 PHASE3
NCT03027167 WITHDRAWN
DVT - Deep Vein Thrombosis; PE - Pulmonary Thromboembolism
Washington University School of Medicine
 2017-01 PHASE4
NCT02164578 COMPLETED
Type 2 Diabetic Patients
GWT-TUD GmbH
 2015-04 PHASE3
NCT02548650 COMPLETED
Myocardial Infarction; Diabetes Mellitus; Peripheral Arterial Disease
University of Florida
 2016-03-25 PHASE4
NCT02689037 UNKNOWN
Intracranial Atherosclerosis
The 476th Hospital of People's Liberation Army
 2016-04 PHASE3
NCT02800252 UNKNOWN
Diabetes Mellitus; Chronic Periodontitis
Universidade Estadual Paulista Júlio de Mesquita Filho
 2016-06
NCT02326350 TERMINATED
Acute Respiratory Distress Syndrome
Belfast Health and Social Care Trust
 2015-02-06 PHASE2
NCT02415400 COMPLETED
Acute Coronary Syndromes
Bristol-Myers Squibb
 2015-06-04 PHASE4
NCT01578629 COMPLETED
Ischemic Stroke; Transient Ischemic Attack (TIA)
Andrew Slivka
 2012-03 PHASE1; PHASE2
NCT03456960 COMPLETED
Healthy Volunteers
Takeda
 2018-03-08 PHASE1
NCT03224923 TERMINATED
Stable Coronary Syndrome; Percutaneous Coronary Intervention; Antiplatelet Therapy; Ticagrelor
Ottawa Heart Institute Research Corporation
 2017-08-18 PHASE4
NCT05604118 COMPLETED
Platelet Dysfunction Due to Aspirin
Cardiff University
 2016-08-01
NCT03528967 COMPLETED
Placental Insufficiency; Enoxaparin
Les Laboratoires des Médicaments Stériles
 2013-10-23 PHASE4
NCT03230851 UNKNOWN
Coronary Atherosclerosis
The First Affiliated Hospital with Nanjing Medical University
 2017-08-20 PHASE4
NCT03008915 COMPLETED
Alpha-1 Antitrypsin Deficiency; Emphysema; Chronic Obstructive Pulmonary Disease
Columbia University
 2017-01 PHASE2
NCT02761486 COMPLETED
Healthy
University of Minnesota
 2016-08 PHASE1
NCT02325466 COMPLETED
Peripheral Artery Disease; Type 2 Diabetes
Icahn School of Medicine at Mount Sinai
 2015-04 PHASE3
NCT02174328 TERMINATED
Pre-Eclampsia
Instituto de Investigacion Sanitaria La Fe
 2014-05-21 PHASE3
NCT02757365 UNKNOWN
Prostate Cancer
West China Hospital
 2014-04 PHASE4
NCT02313909 TERMINATED
Stroke
Bayer
 2014-12-23 PHASE3
NCT02531165 COMPLETED
Acute Myocardial Infarction
Centre Hospitalier Universitaire Vaudois
 2015-09
NCT02970604 UNKNOWN
Cardiovascular Diseases
Royal College of Surgeons, Ireland
 2016-05 PHASE4
NCT01998776 COMPLETED
Ulcer Hemorrhage
Chinese University of Hong Kong
 2013-04 PHASE2; PHASE3
NCT02942680 UNKNOWN
Coronary Heart Disease
Meshalkin Research Institute of Pathology of Circulation
 2016-01 PHASE3
NCT01635426 UNKNOWN
Recurrent Pregnancy Loss
Ain Shams University
 2012-03 PHASE2; PHASE3
NCT03119012 TERMINATED
Coronary Artery Disease; Stents; Atherosclerosis
Samsung Medical Center
 2017-04-19 PHASE4
NCT02642419 UNKNOWN
Atrial Fibrillation
Japan Cardiovascular Research Foundation
 2015-01 PHASE4
NCT02567461 COMPLETED
Coronary Artery Disease
University of Florida
 2016-03 PHASE4
NCT02285738 COMPLETED
Solid Tumor; Cancer
Case Comprehensive Cancer Center
 2014-12-30 EARLY_PHASE1
NCT04371874 COMPLETED
Hypertension
First Affiliated Hospital Xi'an Jiaotong University
 2014-01
NCT01259856 COMPLETED
High Risk Polycythemia Vera; High Risk Essential Thrombocythemia
Ronald Hoffman
 2011-09 PHASE3
NCT01781611 TERMINATED
Systemic Lupus Erythematosus
Oklahoma Medical Research Foundation
 2013-02
NCT02774265 COMPLETED
Venous Thromboembolism; Pulmonary Embolism
University of Maryland, Baltimore
 2016-01 PHASE3
NCT02072226 TERMINATED
Stroke
Genentech, Inc.
 2014-05-31 PHASE3
NCT02407314 TERMINATED
Peripheral Arterial Disease
Arkansas Heart Hospital
 2015-06 PHASE4
NCT02049762 COMPLETED
Acute Coronary Syndrome; Platelet Function and Reactivity Tests; Novel P2Y12 Inhibitors
Sheba Medical Center
 2015-06 PHASE4
NCT02201771 COMPLETED
Coronary Artery Bypass; Antiplatelet Agents
Ruijin Hospital
 2014-07 PHASE4
NCT01597375 COMPLETED
Asthma, Aspirin-Induced; Aspirin Exacerbated Asthma
Elliot Israel, MD
 2012-08-31 PHASE2
NCT00562289 COMPLETED
Ischemic Stroke; Patent Foramen Ovale; Atrial Septal Aneurysm; Migraine
Assistance Publique - Hôpitaux de Paris
 2007-12 PHASE3
NCT02933788 UNKNOWN
Type 2 Diabetes Mellitus
Kangbuk Samsung Hospital
 2016-10 PHASE4
NCT02694848 UNKNOWN
Angina
China Academy of Chinese Medical Sciences
 2016-02 PHASE4
NCT02100462 UNKNOWN
Hypertension
Creighton University
 2014-03 PHASE4
NCT02922673 COMPLETED
Endotoxemia
Radboud University Medical Center
 2016-09
NCT00501059 COMPLETED
Moderate Risk of CVD
Bayer
 2007-07-05 PHASE3
NCT02602938 UNKNOWN
Epithelial-Mesenchymal Transition; Circulating Tumor Cells
Zhejiang Provincial People's Hospital
 2015-11 PHASE2
NCT02301780 COMPLETED
Preeclampsia
Rabin Medical Center
 2015-12 PHASE3
NCT02268565 COMPLETED
Insomnia
Beth Israel Deaconess Medical Center
 2014-10 EARLY_PHASE1
NCT02866448 WITHDRAWN
Cardiovascular Disease
University of Reading
 2016-08
NCT02641080 COMPLETED
Osteoarthritis
West Virginia University
 2016-01
NCT01733485 COMPLETED
Asthma; Electrophilic Fatty Acids
Sally E. Wenzel MD
 2011-10 PHASE1
NCT02483169 UNKNOWN
Brain Ischemia; Intracranial Hemorrhages
Asan Medical Center
 2009-06 PHASE4
NCT01779401 COMPLETED
Coronary Heart Disease
Chinese Academy of Medical Sciences, Fuwai Hospital
 2012-09
NCT01013532 UNKNOWN
Brain Ischemia; Intracranial Hemorrhages
Asan Medical Center
 2009-06 PHASE4
NCT02333123 TERMINATED
Venous Leg Ulcer
St George's, University of London
 2015-07-10 PHASE2
NCT02084615 UNKNOWN
Hernia, Inguinal; Postoperative Complications; Postoperative Hemorrhage
Jesse Brown VA Medical Center
 2014-08
NCT01830543 COMPLETED
Atrial Fibrillation; Percutaneous Coronary Intervention
Janssen Scientific Affairs, LLC
 2013-05-10 PHASE3
NCT01720108 COMPLETED
Venous Thromboembolism
David Anderson
 2013-02-24 PHASE3
NCT02237365 COMPLETED
Tuberculous Meningitis
Oxford University Clinical Research Unit, Vietnam
 2014-10-17 PHASE2
NCT02291419 TERMINATED
Myocardial Injury
The Cleveland Clinic
 2015-07 PHASE4
NCT01514227 COMPLETED
Coronary Artery Disease
Associations for Establishment of Evidence in Interventions
 2011-12 PHASE4
NCT02201394 COMPLETED
Coronary Artery Disease
Icahn School of Medicine at Mount Sinai
 2014-07 PHASE4
NCT02227368 TERMINATED
Peripheral Artery Disease (PAD)
AstraZeneca
 2014-10-20 PHASE2
NCT01994720 COMPLETED
Acute Ischaemic Stroke; Transient Ischaemic Attack
AstraZeneca
 2014-01-07 PHASE3
NCT02607436 COMPLETED
Coronary Artery Disease
Seoul National University Bundang Hospital
 2015-07 PHASE4
NCT01924325 UNKNOWN
Ischemic Stroke; TIA
Xijing Hospital
 2014-01 PHASE2; PHASE3
NCT02878772 COMPLETED
Stroke; Immunoregulation; Inflammation; Vinpocetine
Tianjin Medical University General Hospital
 2014-05 PHASE2; PHASE3
NCT01740921 COMPLETED
Type 2 Diabetes
Royal Devon and Exeter NHS Foundation Trust
 2011-01
NCT01408186 COMPLETED
Upper Gastrointestinal Bleeding
Chinese University of Hong Kong
 2011-01 PHASE3
NCT01741922 COMPLETED
Hypertension
Basque Health Service
 2012-12 PHASE3
NCT01047722 UNKNOWN
Healthy
Klein, Jeffrey A., M.D.
 2010-01 PHASE1
NCT01322711 UNKNOWN
Type 2 Diabetes Mellitus; Hypercholesterolemia
University of Roma La Sapienza
 2011-03 PHASE4
NCT01504867 COMPLETED
Acute Respiratory Distress Syndrome
Mayo Clinic
 2012-01 PHASE2
NCT02341638 COMPLETED
Thrombosis
Bristol-Myers Squibb
 2014-09 PHASE1
NCT01549418 UNKNOWN
Gastrointestinal Hemorrhage
Maria Sklodowska-Curie National Research Institute of Oncology
 2012-09 PHASE4
NCT01668901 WITHDRAWN
Atrial Fibrillation; Chronic Kidney Disease
Seoul National University Hospital
 2012-09 PHASE4
NCT02209909 COMPLETED
Coronary Artery Disease
Seoul National University Hospital
 2014-07
NCT01429272 COMPLETED
Bipolar Disorder Depression
Laureate Institute for Brain Research, Inc.
 2011-09 PHASE3
NCT01058902 WITHDRAWN
Non Small Cell Lung Cancer; Survival; Aspirin
Liverpool Heart and Chest Hospital NHS Foundation Trust
 2010-08 PHASE3
NCT01547390 TERMINATED
Preeclampsia
Washington University School of Medicine
 2012-03
NCT02402491 UNKNOWN
Percutaneous Coronary Intervention
Beijing Anzhen Hospital
 2013-01 PHASE4
NCT02221102 UNKNOWN
Ischemia; Stroke; Cerebral Infarction
Xijing Hospital
 2013-12 PHASE2; PHASE3
NCT02229461 COMPLETED
Hematology
Bayer
 2015-02 PHASE1
NCT01616615 COMPLETED
Placental Insufficiency
Sara Varea
 2012-09 PHASE2
NCT02234427 COMPLETED
Atherosclerosis
Johns Hopkins University
 2014-06 PHASE4
NCT01965002 TERMINATED
Soft Tissue Neoplasms
Pejman Ghanouni
 2014-05
NCT03587324 COMPLETED
Vascular Surgery Patient With PAD / Carotid Stenosis
St. Josef Hospital Bochum
 2013-02
NCT01373411 COMPLETED
Coronary Artery Disease
Cardiology Research UBC
 2011-09 PHASE4
NCT01470040 UNKNOWN
Head Trauma; Traumatic Brain Injury; Chronic Subdural Hematoma
Hadassah Medical Organization
 2012-02 PHASE4
NCT03116269 COMPLETED
Ischemic Stroke; Endothelial Dysfunction
Ajou University School of Medicine
 2012-03-01 PHASE4
NCT01388660 UNKNOWN
Coronary Artery Disease
Ajou University School of Medicine
 2011-06 PHASE1
NCT01710072 COMPLETED
The Focus of the Study is to Monitor MRI Signal Changes and Inflammatory Biomarkers With Use of Aspirin in Patients With Unruptured Cerebral Aneurysm
University of Iowa
 2011-08 PHASE1
NCT01665235 UNKNOWN
Blood Pressure Variability; Intracranial Artery Stenosis
RenJi Hospital
 2012-08
NCT01431053 UNKNOWN
Breast Neoplasms
Chinese Academy of Medical Sciences
 2011-07 PHASE2
NCT02630862 COMPLETED
Carotid Stenosis; Cardiovascular Disease; Atherosclerosis; Stroke
University of Roma La Sapienza
 2010-09
NCT00805311 TERMINATED
Carotid Artery Stenosis; Atherosclerosis; Stroke
Russian Cardiology Research and Production Center
 2009-04 PHASE4
NCT01629329 TERMINATED
Migraine Headaches
Albert Einstein Healthcare Network
 2010-11 PHASE4
NCT02008981 COMPLETED
Platelet Function Test
Singapore General Hospital
 2013-12 PHASE3
NCT00910065 COMPLETED
Acute Coronary Syndrome
Bayer
 2011-03 PHASE3
NCT01778465 COMPLETED
Chronic Rhinosinusitis; Aspirin Exacerbated Respiratory Disease; Asthma; Aspirin Sensitivity
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
 2013-05
NCT02071004 COMPLETED
Acute Ischemic Stroke
Daiichi Sankyo
 2014-01 PHASE1
NCT01900639 COMPLETED
Aspirin; Circadian Rhythm; Platelet Activation; Cardiovascular Diseases
Leiden University Medical Center
 2013-07 PHASE4
NCT00776633 UNKNOWN
Coronary Artery Disease; Atrial Fibrillation
Deutsches Herzzentrum Muenchen
 2008-09 PHASE4
NCT01598337 UNKNOWN
Coronary Artery Disease
Prince Sultan Cardiac Center, Adult Cardiology Department.
 2011-04 PHASE3
NCT01398410 COMPLETED
Gastric Ulcers Duodenal Ulcers Caused by Low-dose Aspirin
Eisai Co., Ltd.
 2011-12 PHASE2; PHASE3
NCT00578721 COMPLETED
Colorectal Cancer
University of California, Irvine
 2008-09-24 PHASE2
NCT01917799 UNKNOWN
Pregnancy; Miscarriage
University of Khartoum
 2009-01 PHASE4
NCT01456247 COMPLETED
Gastric Ulcers; Duodenal Ulcers
Takeda
 2012-03 PHASE3
NCT01426438 COMPLETED
HIV-1 Infection
Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
 2011-11 PHASE2
NCT01466452 UNKNOWN
Coronary Arteriosclerosis
Centro Cardiologico Monzino
 2011-09 PHASE2
NCT01847404 COMPLETED
Ulcers, Duodenal and Gastric
GlaxoSmithKline
 2013-05-14 PHASE1
NCT01618006 COMPLETED
Postoperative; Dysfunction Following Cardiac Surgery
Hamilton Health Sciences Corporation
 2012-01 PHASE2
NCT01452763 COMPLETED
Gastric Ulcers; Duodenal Ulcers
Takeda
 2011-10 PHASE3
NCT01642238 COMPLETED
Acute Coronary Syndrome
Juan J Badimon
 2012-07 PHASE4
NCT01612247 UNKNOWN
Breast Cancer
University of Vermont
 2011-02
NCT01159639 COMPLETED
Coronary Artery Disease; Aspirin Resistance
University of Zagreb
 2010-06 PHASE4
NCT02786979 TERMINATED
Type 2 Diabetes Mellitus
Astellas Pharma Inc
 2010-07 PHASE4
NCT01612273 COMPLETED
Vasospastic Syndrome
Yonsei University
 2011-04 PHASE4
NCT01192724 COMPLETED
Coronary Artery Disease
Yonsei University
 2010-03 PHASE4
NCT01696760 COMPLETED
Bone Metastases; Musculoskeletal Cancer; Soft Tissue Sarcoma; Thromboembolism
Ohio State University Comprehensive Cancer Center
 2010-10
NCT01518231 UNKNOWN
Stroke
Zhejiang Hospital
 2012-01 PHASE1
NCT01568112 COMPLETED
Healthy
Biogen
 2012-04 PHASE3
NCT01513070 COMPLETED
Coronary Artery Stenosis; Coronary Heart Disease
Guang'anmen Hospital of China Academy of Chinese Medical Sciences
 2012-04 PHASE4
NCT00942617 WITHDRAWN
Platelet Aggregation
Vanderbilt University
 2009-07
NCT01496521 UNKNOWN
Carcinoma, Squamous Cell
Beijing Friendship Hospital
 2012-01 PHASE3
NCT00059306 COMPLETED
Cerebrovascular Accident; Hypertension
University of British Columbia
 2003-02 PHASE3
NCT01448031 COMPLETED
Healthy
AstraZeneca
 2011-11 PHASE1
NCT01657071 COMPLETED
Acute Coronary Syndrome
Yuhan Corporation
 2012-03 PHASE1
NCT01094457 COMPLETED
Acute Coronary Syndromes; Percutaneous Coronary Intervention; Clopidogrel Low Responsiveness
Shenyang Northern Hospital
 2009-03 PHASE4
NCT01572961 COMPLETED
Physiology of Microvascular Skin
University Hospital, Angers
 2010-11
NCT01181882 COMPLETED
Cardiovascular Disease
University of Rochester
 2010-08 PHASE2
NCT00963443 COMPLETED
Common Cold
Bayer
 2009-09 PHASE3
NCT00960869 COMPLETED
Gastric Ulcer
POZEN
 2009-10 PHASE3
NCT00222677 UNKNOWN
Venous Thromboembolism; Deep Venous Thrombosis; Pulmonary Embolism; Atherosclerosis
University Of Perugia
 2004-05 PHASE2; PHASE3
NCT01438580 COMPLETED
Atrial Fibrillation
Nanjing Medical University
 2010-01 PHASE4
NCT01050153 COMPLETED
Venous Thromboembolism
Denver Health and Hospital Authority
 2010-03
NCT01420094 COMPLETED
Healthy Subjects
Bayer
 2011-06-16 PHASE3
NCT01448330 COMPLETED
Healthy
Hanmi Pharmaceutical Company Limited
 2011-07 PHASE1
NCT01496261 COMPLETED
Coronary Artery Disease
Chong Kun Dang Pharmaceutical
 2011-08 PHASE1
NCT00753935 COMPLETED
Coronary Artery Disease
Vanderbilt University
 2006-06 EARLY_PHASE1
NCT01375400 UNKNOWN
Ischemic Stroke
Central Hospital, Nancy, France
 2010-12
NCT00724724 UNKNOWN
Stroke; Transient Ischemic Attack
Peking Union Medical College Hospital
 2008-08 PHASE4
NCT01066923 COMPLETED
Heat Stress Disorders
Dave Hostler
 2010-02
NCT01135862 UNKNOWN
Aspirin Treatment; Traumatic Intracranial Bleed; Hemorrhage Growth; Neurological Outcome
Tel-Aviv Sourasky Medical Center
 2010-06 PHASE2
NCT00995410 COMPLETED
Aspirin-Associated Gastric Ulcers
POZEN
 2009-10 PHASE3
NCT01023243 COMPLETED
Diabetes
Mayo Clinic
 2010-01
NCT01268917 UNKNOWN
Coronary Artery Disease; Off-pump Coronary Artery Bypass; Aspirin
Chinese Academy of Medical Sciences, Fuwai Hospital
 2010-03 PHASE3
NCT01663038 COMPLETED
Coronary Artery Disease
Chong Kun Dang Pharmaceutical
 2010-12 PHASE1
NCT01102439 COMPLETED
Coronary Artery Disease
Population Health Research Institute
 2010-04 PHASE4
NCT00854776 UNKNOWN
Peptic Ulcer; Ulcer Complications
Taipei Veterans General Hospital, Taiwan
 2009-01
NCT00727948 COMPLETED
Breast Cancer; Angiogenesis
University of Vermont
 2008-07 EARLY_PHASE1
NCT01201785 COMPLETED
Type 2 Diabetes Mellitus; Coronary Artery Disease
University of Florida
 2009-01 PHASE4
NCT00482261 COMPLETED
Multiple Myeloma
Peter MacCallum Cancer Centre, Australia
 2007-06 PHASE2
NCT01122602 COMPLETED
Drugs, Investigational
Bayer
 2010-04-29 PHASE3
NCT01117636 COMPLETED
Drugs, Investigational
Bayer
 2010-04-28 PHASE3
NCT00222261 COMPLETED
Coronary Heart Disease; Angina Pectoris; Atherosclerosis
Ullevaal University Hospital
 2003-04 PHASE4
NCT00743197 TERMINATED
Chest Pain
Northwestern University
 2008-05
NCT00590174 COMPLETED
Coronary Artery Disease
Seung-Jung Park
 2007-10 PHASE4
NCT00484926 COMPLETED
Coronary Artery Disease
Seung-Jung Park
 2007-03 PHASE4
NCT01212302 COMPLETED
Coronary Artery Disease
Ruhr University of Bochum
 2008-10
NCT01510327 COMPLETED
Coronary Artery Disease
Boston Scientific Corporation
 2009-10 PHASE3
NCT00783614 TERMINATED
HIV Infection
Hennepin Healthcare Research Institute
 2008-10 PHASE2
NCT00061373 COMPLETED
Ischemic Stroke
National Institute of Neurological Disorders and Stroke (NINDS)
 2003-05 PHASE2
NCT00384865 TERMINATED
Hypertension, Pulmonary
University of Pennsylvania
 2006-09 PHASE2
NCT00790452 TERMINATED
Glioblastoma
M.D. Anderson Cancer Center
 2008-11 PHASE2
NCT00948987 COMPLETED
Aspirin Resistance; Pharmacological Aspirin Non-responsiveness
University of Pennsylvania
 2004-09 PHASE1
NCT00872534 COMPLETED
Upper Gastrointestinal Mucosal Damage
PLx Pharma
 2009-01 PHASE1; PHASE2
NCT00272337 COMPLETED
Cardiovascular Diseases; Atherosclerosis; Myocardial Infarction
Florida Atlantic University
 2006-10 PHASE4
NCT00891670 UNKNOWN
Coronary Artery Stenosis; Maximal Platelet Aggregation; Late Platelet Aggregation; High Post-Treatment Platelet Reactivity
Gyeongsang National University Hospital
 2009-05 PHASE3
NCT00734123 UNKNOWN
Atherosclerosis; Cardiovascular Diseases
Hospital Arnau de Vilanova
 2008-04 PHASE4
NCT00528411 COMPLETED
Coronary Artery Disease
AstraZeneca
 2007-10 PHASE2
NCT00713947 WITHDRAWN
Positive Helicobacter Pylori Serology; Coronary Thrombosis; Supra-aortic Artery Thrombosis
Assistance Publique - Hôpitaux de Paris
 2008-04 PHASE4
NCT00311402 COMPLETED
Cerebrovascular Accident
Boehringer Ingelheim
 2006-04 PHASE3
NCT00815126 COMPLETED
Aspirin Hypersensitivity; NSAIDs Hypersensitivity
Chulalongkorn University
 2008-11
NCT00642811 COMPLETED
Stable Coronary Artery Disease
AstraZeneca
 2008-05 PHASE2
NCT00775762 UNKNOWN
Polyvascular Disease; Cardiovascular Disease
Catholic University of the Sacred Heart
 2008-11 PHASE3
NCT00861367 WITHDRAWN
Blood Loss, Surgical; Intraoperative Complications; Re-operation Rates in Patients With Aspirin Treatment
University Hospital, Basel, Switzerland
 2008-09
NCT00620646 COMPLETED
Clopidogrel Non-Responsiveness
Samsung Medical Center
 2008-02
NCT00449618 TERMINATED
High-Normal Blood Pressure; Mild Essential Hypertension
University of Vigo
 2007-01 PHASE4
NCT00762359 TERMINATED
Stomach Ulcer; Duodenal Ulcer
Takeda
 2007-05 PHASE3
NCT00443794 COMPLETED
Cardiovascular Diseases
St. John's Research Institute
 2007-03
NCT00587496 UNKNOWN
Herpes Simplex
National Eye Institute (NEI)
 2006-04 PHASE1
NCT02251795 COMPLETED
Healthy
Boehringer Ingelheim
 2007-08 PHASE1
NCT01353144 COMPLETED
Peptic Ulcer
Kaohsiung Veterans General Hospital.
 2007-06 PHASE4
NCT00631111 COMPLETED
Pain
Wyeth is now a wholly owned subsidiary of Pfizer
 2007-11 PHASE3
NCT00244426 COMPLETED
Atrial Fibrillation
Pfizer
 2000-12 PHASE3
NCT00632086 COMPLETED
Healthy
POZEN
 2008-02 PHASE1
NCT00067119 COMPLETED
Kidney Failure
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
 2003-01-01 PHASE3
NCT00262561 COMPLETED
Intermittent Claudication
Aalborg University Hospital
 2006-01 PHASE4
NCT00594867 COMPLETED
Healthy
University of Illinois at Chicago
 2006-12 PHASE4
NCT00684203 COMPLETED
Atherosclerosis; Myocardial Ischemia; Myocardial Infarction
Merck Sharp & Dohme LLC
 2006-12-01 PHASE2
NCT01061034 COMPLETED
Aspirin Blood Level; Proton Pump Inhiditor Treatment
Assaf-Harofeh Medical Center
 2007-03
NCT00129038 COMPLETED
Coronary Arteriosclerosis
Boehringer Ingelheim
 2004-04-01 PHASE4
NCT00386529 COMPLETED
Well-controlled Hypertension
Boryung Pharmaceutical Co., Ltd
 2006-09 PHASE4
NCT00325715 COMPLETED
Peptic Ulcer
Allergan
 2006-04 PHASE1
NCT00898950 COMPLETED
Diabetes Type 2
University of Portsmouth
 2004-08
NCT00260377 TERMINATED
Ischemic Heart Disease
Sheba Medical Center
 2005-01
NCT00683202 COMPLETED
Pregnancy; Miscarriage Less Than 12 Gestational Weeks; Extrauterine Pregnancy; Preeclampsia; Intrauterine Fetal Growth Restriction
University of Oulu
 2001-03
NCT00054938 COMPLETED
Systemic Lupus Erythematosus; Lupus
Brigham and Women's Hospital
 2003-03 PHASE2
NCT00243178 TERMINATED
Atrial Fibrillation; Vascular Risk
Sanofi
 2003-07 PHASE3
NCT00062023 TERMINATED
Colorectal Cancer
M.D. Anderson Cancer Center
 2003-06 PHASE2
NCT00543465 TERMINATED
Arthritis, Rheumatoid; Osteoarthritis
Merck Sharp & Dohme LLC
 2004-08 PHASE2
NCT00129805 COMPLETED
Cerebral Infarction
Tanabe Pharma Corporation
 2001-01 PHASE3
NCT00175032 COMPLETED
Osteoarthritis; Peptic Ulcer
Takeda
 2003-07 PHASE3
NCT02251184 COMPLETED
Healthy
Boehringer Ingelheim
 2000-10 PHASE4
NCT00697151 COMPLETED
Ischemic Stroke; Patent Foramen Ovale
Columbia University
 1993-06 PHASE4
NCT00000527 COMPLETED
Cardiovascular Diseases; Carotid Stenosis; Cerebrovascular Disorders; Heart Diseases; Vascular Diseases
Emory University
 1986-08 PHASE2
NCT00000500 COMPLETED
Cardiovascular Diseases; Coronary Disease; Heart Diseases; Myocardial Ischemia
Brigham and Women's Hospital
 1981-09 PHASE3
NCT00286416 UNKNOWN
Asthma; Allergic Rhinitis
Scripps Clinic
 2006-01
NCT00349661 COMPLETED
Coronary Heart Disease
University Hospital, Brest
 2006-06 PHASE3
NCT00000161 UNKNOWN
Macular Degeneration; Cataract
National Eye Institute (NEI)
 1993-08 PHASE3
NCT00466154 COMPLETED
Aspirin Resistance; Hypercholesterolemia
Ziv Hospital
 2005-07
NCT00224679 TERMINATED
Colon Adenomas
Assistance Publique - Hôpitaux de Paris
 1997-03 PHASE3
NCT00331786 COMPLETED
Colorectal Cancer
Stony Brook University
 2006-07 PHASE1
NCT00153725 COMPLETED
Cardiovascular Disease; Cerebrovascular Disorders
Chinese University of Hong Kong
 2003-02
NCT00004727 COMPLETED
Stroke; Cerebral Infarction
National Institute of Neurological Disorders and Stroke (NINDS)
 PHASE4
NCT00272454 COMPLETED
Cerebral Infarction
Korea Otsuka Pharmaceutical Co., Ltd.
 2006-01 PHASE4
NCT00664040 COMPLETED
Cardiovascular Diseases
University of Maryland, Baltimore
 2003-05
NCT00000520 COMPLETED
Cardiovascular Diseases; Coronary Aneurysm; Heart Diseases; Mucocutaneous Lymph Node Syndrome
National Heart, Lung, and Blood Institute (NHLBI)
 1985-07 PHASE2
NCT00442052 COMPLETED
Healthy
POZEN
 2006-11 PHASE1
NCT00389129 COMPLETED
Drug Resistance
University of Aarhus
 2006-11
NCT00427271 UNKNOWN
Diabetes Mellitus; Microalbuminuria
Hospital de Clinicas de Porto Alegre
 2003-03 PHASE4
NCT00536068 COMPLETED
Hemostasis
Kantonsspital Graubünden
 2006-08
NCT00126139 TERMINATED
Stroke; Stenosis
University of Zurich
 2004-04 PHASE3
NCT00442585 COMPLETED
Drug Interactions
Gebro Pharma GmbH
 2006-09 PHASE1
NCT00265408 WITHDRAWN
Ischemic Stroke
University of California, San Diego
 2005-12 PHASE1
NCT00262977 COMPLETED
Diabetes Mellitus
Northwestern University
 2004-09
NCT00202020 COMPLETED
Cerebral Infarction
Otsuka Beijing Research Institute
 2004-05 PHASE3
NCT00109382 COMPLETED
Transient Ischemic Attack; Stroke
University of Calgary
 2003-05 PHASE2; PHASE3
NCT00224809 COMPLETED
Cardiovascular Diseases; Heart Diseases; Coronary Disease
Baylor Research Institute
 2002-09
NCT00000151 COMPLETED
Blindness; Diabetic Retinopathy
National Eye Institute (NEI)
 1979-12 PHASE3
NCT00238667 COMPLETED
Cervical Artery Dissection; Carotid Artery Dissection; Vertebral Artery Dissection; Stroke
St George's, University of London
 2005-11 PHASE3

(data from https://clinicaltrials.gov, updated on 2026-05-11)

Check the Aspirin product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Compliance for Clinical Use

Mechanism and Biochemical Profile

Aspirin acts by covalently acetylating and irreversibly inhibiting cyclooxygenase-1 and cyclooxygenase-2, thereby blocking the conversion of arachidonic acid into pro-inflammatory prostaglandins and thromboxanes. This enzymatic blockade attenuates mediator-driven cellular inflammation and vascular activation, providing therapeutic relevance in clinical trial settings for conditions such as coronary artery disease, inflammatory arthritis, and colorectal neoplasia.

Appendix RUO and cGMP Quality Standards

Quality Dimension RUO (Research Use Only) cGMP (Current Good Manufacturing Practice)
Clinical Applicability Prohibited in human clinical trials or medical diagnostics. Mandatory for human clinical trials (Phase I–III) and therapies.
Regulatory Status Non-regulated grade; exempt from drug manufacturing laws. Legally enforced by health authorities (e.g., FDA, EMA, NMPA).
Facility Environment Unclassified analytical or research laboratories. Validated Cleanrooms (ISO Class 5–8) with continuous monitoring.
Quality Control Basic purity and activity testing. Rigorous safety release testing (Sterility, Endotoxin, Mycoplasma).
Process Validation Basic equipment calibration; no process validation required. Full qualification (IQ/OQ/PQ) and complete batch records.
Quality Assurance Vendor self-declared without required formal QMS. Mandatory QA/QC unit, Change Control, CAPA, and vendor audits.
Regulatory Impact High risk of IND rejection if used as a critical raw material. Required for IND/NDA filings, supported by Drug Master Files (DMF).

Footnotes

Regulatory Note: Governed by FDA (21 CFR Parts 210/211/312), EMA (EudraLex Vol 4), ICH Guidelines (E6/Q7/Q9/Q10), and compendial standards (USP <71>/<85>/<1043>).

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Note: Technical data last updated: Sep 1, 2026.