2D Structure
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2D chemical structural formula diagram.
3D Structure
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This 3D model represents a theoretically simulated conformation and is for reference only.
Check the
ABL001 (Asciminib)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | N-[4-[chloro(difluoro)methoxy]phenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide | |
|---|---|---|
| CAS Number | 1492952-76-7 | |
| Molecular Formula |
C20H18ClF2N5O3 |
|
| Molecular Weight (MW) | 449.84 | |
| SMILES | C1CN(CC1O)C2=C(C=C(C=N2)C(=O)NC3=CC=C(C=C3)OC(F)(F)Cl)C4=CC=NN4 | |
| InChIKey | VOVZXURTCKPRDQ-CQSZACIVSA-N |
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
89 mg/mL
(197.84 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 89 mg/mL |
| Water | Insoluble |
| DMSO |
90 mg/mL
(200.07 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 23 mg/mL |
| Water | Insoluble |
| DMSO |
90 mg/mL
(200.07 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 30 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
- ABL001 (Asciminib) Mechanism of Action: BCR-ABL1 Inhibition in Myeloid Cells Research
- ABL001 (Asciminib) Clinical Trials
- ABL001 (Asciminib): Selectivity & Specificity
- ABL001 (Asciminib) Working Concentration | Cell Culture | Treatment
- ABL001 (Asciminib) Solubility in DMSO
- ABL001 (Asciminib) Stock Solution
- ABL001 (Asciminib) Storage
- ABL001 (Asciminib) Stability
- ABL001 (Asciminib) Combination Database
- ABL001 (Asciminib) Molecular Weight
- ABL001 (Asciminib) SMILES
- ABL001 (Asciminib) CAS Number
- ABL001 (Asciminib) IC50 for Cell-based and Cell-free Assays
- ABL001 (Asciminib) Sigma (BL3H160C4B14)? Try a better option.
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- ABL001 (Asciminib) SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.