Apatinib (YN968D1) is a potent, highly selective, ATP-competitive VEGFR2 inhibitor. It affects VEGF/VEGFR signaling by binding to the intracellular ATP-binding site to prevent receptor phosphorylation, effectively inhibiting tumor angiogenesis and endothelial cell proliferation.
Apatinib (YN968D1) IC50 for Cell-based and Cell-free Assays
Comprehensive IC50 Values for Apatinib (YN968D1) Across Cell-free Enzyme Inhibitory Profiles and Cell-based Functional Assays.