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For research use only. Not for use in humans.

Anti-TREM2 (Py314)

Synonyms: TREM-2， Triggering receptor expressed on myeloid cells 2

Anti-TREM2 (Py314) is a humanized monoclonal antibody that specifically targets the triggering receptor expressed on myeloid cells 2 (TREM2). It can be used in cancer research and in treatment of variety of solid tumor types. MW :145.24 KD.

Anti-TREM2 (Py314)

Quality Control

Batch: A316901 Purity: 99% Protein concentration: 8.48mg/ml Endotoxin Level: ＜1EU/mg
99

Mechanism of Action

Description
Anti-TREM2 (Py314) is a humanized monoclonal antibody that specifically targets the triggering receptor expressed on myeloid cells 2 (TREM2). It can be used in cancer research and in treatment of variety of solid tumor types. MW :145.24 KD.
References

Product Details

Isotype Human IgG1
Source CHO
Formulation 100 mM Pro-Ac, 20mM Arg, pH5.0
Storage
(From the date of receipt)		 Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04691375 TERMINATED Drug: PY314|Drug: Combination Therapy: PY314 + Pembrolizumab Advanced Solid Tumor; Gynecologic Cancer; Breast Cancer; Colorectal Cancer; Lung Adenocarcinoma; Renal Cell Carcinoma; Triple Negative Breast Cancer; Hormone Receptor/Growth Factor Receptor-Negative Breast Cancer; Ovarian Cancer Ikena Oncology 2020-10-29 PHASE1

(data from https://clinicaltrials.gov, updated on 2024-03-22)

Tech Support

Handling Instructions

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