Home Biosimilar Antibodies Others Others Anti-TfR (Jr-141)
For research use only. Not for use in humans.

Anti-TfR (Jr-141)

Synonyms: TFRC， CD71

Anti-TfR (Jr-141), is an antibody targeting human transferrin receptor (hTfR). It can be used in treatment of patients with mucopolysaccharidosis II (MPS II) and CNS disorders. MW :146.02 KD.

Anti-TfR (Jr-141)

Quality Control

Batch: A316501 Purity: 99% Protein concentration: 6.688mg/ml Endotoxin Level: ＜1EU/mg
99

Mechanism of Action

Description
Anti-TfR (Jr-141), is an antibody targeting human transferrin receptor (hTfR). It can be used in treatment of patients with mucopolysaccharidosis II (MPS II) and CNS disorders. MW :146.02 KD.
References

Product Details

Isotype Human IgG1
Source CHO
Formulation 100 mM Pro-Ac, 20mM Arg, pH5.0
Storage
(From the date of receipt)		 Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04348136 ACTIVE_NOT_RECRUITING Drug: JR-141 Mucopolysaccharidosis II JCR Pharmaceuticals Co., Ltd. 2019-09-01 PHASE2; PHASE3
NCT05594992 ENROLLING_BY_INVITATION Drug: JR-141 Mucopolysaccharidosis II JCR Pharmaceuticals Co., Ltd. 2023-02-22 PHASE3
NCT04573023 ACTIVE_NOT_RECRUITING Drug: JR-141|Drug: Idursulfase|Drug: JR-141 or Idursulfase Mucopolysaccharidosis II JCR Pharmaceuticals Co., Ltd. 2022-02-14 PHASE3
NCT03708965 ACTIVE_NOT_RECRUITING Drug: JR-141 Mucopolysaccharidosis II JCR Pharmaceuticals Co., Ltd. 2019-01-01 PHASE2
NCT03568175 COMPLETED Drug: JR-141 Mucopolysaccharidosis II JCR Pharmaceuticals Co., Ltd. 2018-08-01 PHASE2; PHASE3
NCT03359213 COMPLETED Drug: JR-141|Drug: JR-141|Drug: JR-141 Mucopolysaccharidosis II JCR Pharmaceuticals Co., Ltd. 2018-07-26 PHASE2

(data from https://clinicaltrials.gov, updated on 2026-09-03)

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