For research use only. Not for use in humans.

Anti-GPR49 / LGR5 (BNC101)

Synonyms: BNC101

Anti-GPR49 / LGR5 (BNC101) is a human specific monoclonal antibody targeting the GPCR-LGR5. It can be used in the treatment of metastatic colorectal cancer (CRC). MW :150 KD.

Anti-GPR49 / LGR5 (BNC101)

Quality Control

  • Cited in Nature Medicine for its top-tier quality
  • SDS
  • Datasheet

Specificity

Name Citation GPR Others
AZD1981 1
NF-56-EJ40 0
ML401 0
PH-064 0
NE 52-QQ57 1 IL-1β,TNF-α,PGE2
NIBR189 0
JMS-17-2 2
OC000459 0
Kisspeptin-10 (human) 0
CLP-3094 0 AR
Expand to Check More
1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Mechanism of Action

Description
Anti-GPR49 / LGR5 (BNC101) is a human specific monoclonal antibody targeting the GPCR-LGR5. It can be used in the treatment of metastatic colorectal cancer (CRC). MW :150 KD.
References

Product Details

Molecular Weight 150
Isotype Human IgG1
Source CHO
Purification AKTA
Sterility 0.2 μM filtered
Formulation 100 mM Pro-Ac, 20mM Arg, pH5.0
Storage
(From the date of receipt)
Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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