For research use only. Not for use in humans.

Anti-ANGPT2 (MEDI3617)

Synonyms: null Cat.No.A2770 Purity:99%

Anti-ANGPT2 (MEDI3617) is a human IgG1 kappa monoclonal antibody directed against the angiogenic cytokines angiopoietin-2 (Angpt2). MEDI3617 in combination with tremelimumab is used to treat advanced melanoma. MW: 145.82 kD.

Quality Control

Batch: A277001 Purity: 99% Protein concentration: 13mg/ml Endotoxin Level: ＜1EU/mg

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COA
SDS
Datasheet

Mechanism of Action

Description	Anti-ANGPT2 (MEDI3617) is a human IgG1 kappa monoclonal antibody directed against the angiogenic cytokines angiopoietin-2 (Angpt2). MEDI3617 in combination with tremelimumab is used to treat advanced melanoma. MW: 145.82 kD.
References	[1] https://pubmed.ncbi.nlm.nih.gov/34772758/

Cell Lines	Assay Type	Concentration	Incubation Time	Formulation	Activity Description	PMID

Product Details

Molecular Weight	145.82
Isotype	Human IgG2SA
Source	CHO
Purification	AKTA
Sterility	0.2 μM filtered
Formulation	100 mM Pro-Ac, 20mM Arg, pH5.0
Storage (From the date of receipt)	Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

^*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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