CAS No. 861998-00-7

Batch: Purity:98.96
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AnaMorelin hydrochloride Chemical Structure
Chemical Structure
Check the AnaMorelin hydrochloride product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name 2-amino-N-[(2R)-1-[(3R)-3-benzyl-3-[dimethylamino(methyl)carbamoyl]piperidin-1-yl]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-2-methylpropanamide;hydrochloride
CAS Number 861998-00-7
Molecular Formula

C31H42N6O3.ClH
Molecular Weight (MW) 583.17
InChIKey VFYAEUWJFGTGGO-GHTUPXNNSA-N

Ordering Information

Biological Activity

Anamorelin hydrochloride is a selective ghrelin receptor agonist with an EC50 of. Activation of the growth hormone secretagogue receptor by this compound triggers intracellular calcium mobilization and downstream growth hormone release. This pathway activation enhances appetite and promotes food intake, counteracting metabolic alterations associated with cancer anorexia-cachexia syndrome in preclinical models. [1]

How to Prepare Stock Solution?

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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 100 mg/mL (171.47 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 100 mg/mL
Ethanol 100 mg/mL
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.