CAS No. 137-88-2
Batch:
Purity:99.76
Chemical Structure
Check the
Amprolium HCl
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 137-88-2 | |
|---|---|---|
| Molecular Formula |
C14H19N4.HCl.Cl |
|
| Molecular Weight (MW) | 315.24 | |
| SMILES | CCCC1=NC=C(C(=N1)N)C[N+]2=CC=CC=C2C.Cl.[Cl-] |
Amprolium HCl is a thiamine antagonist that functions by blocking cellular thiamine uptake. By competitively inhibiting thiamine transport mechanisms across cellular membranes, it prevents the intracellular accumulation of thiamine necessary for cofactor synthesis. This blockade disrupts thiamine-dependent carbohydrate metabolism pathways and downstream energy production, ultimately suppressing carbohydrate synthesis and cellular metabolic function.
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| Water | 63 mg/mL |
| DMSO |
2 mg/mL
(6.34 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
Note: Technical data last updated: Sep 1, 2026.