CAS No. 1617-53-4
Batch:
Purity:99.94
Chemical Structure
Check the
Amentoflavone
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 8-[5-(5,7-dihydroxy-4-oxochromen-2-yl)-2-hydroxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one | |
|---|---|---|
| CAS Number | 1617-53-4 | |
| Molecular Formula |
C30H18O10 |
|
| Molecular Weight (MW) | 538.46 | |
| InChIKey | YUSWMAULDXZHPY-UHFFFAOYSA-N |
Amentoflavone is a naturally occurring biflavonoid compound possessing antibacterial, antioxidant, antiviral, antidiabetic, and neuroprotective biological activities. It modulates key cellular signaling cascades, suppressing NF-kB pathway activation to attenuate downstream inflammatory cytokine expression. Furthermore, amentoflavone mitigates cellular oxidative stress and inhibits pro-apoptotic signaling, promoting neuronal cell survival and metabolic homeostasis in preclinical experimental models.
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(185.71 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| DMSO |
100 mg/mL
(185.71 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 100 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.