CAS No. 5560-59-8
| CAS Number | 5560-59-8 | |
|---|---|---|
| Molecular Formula |
C20H27N.C6H8O7 |
|
| Molecular Weight (MW) | 473.56 | |
| SMILES | CCN(CCCC1=CC=CC=C1)CCCC2=CC=CC=C2.C(C(=O)O)C(CC(=O)O)(C(=O)O)O |
Alverine citrate is a small-molecule 5-HT1A receptor antagonist evaluated for the treatment and study of functional gastrointestinal disorders. Selective inhibition of the 5-HT1A receptor attenuates G protein-coupled receptor signalling cascades, directly influencing downstream adenylyl cyclase activity and cellular second messengers. Consequently, this pathway modulation impacts gastrointestinal smooth muscle contractility, visceral sensitivity, and neuromuscular regulation within the digestive system.
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Concentration
Volume
Mass
|
|---|
| Solvent | Solubility & Note |
|---|---|
| DMSO |
95 mg/mL
(200.6 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
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