SMILES:

C1CSSC1CCCCC(=O)O
(+)-α-Lipoic acid Chemical Structure
Chemical Structure
Check the (+)-α-Lipoic acid product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name 5-[(3R)-dithiolan-3-yl]pentanoate
CAS Number 1200-22-2
Molecular Formula

C8H14O2S2
Molecular Weight (MW) 206.33
SMILES C1CSSC1CCCCC(=O)O
InChIKey AGBQKNBQESQNJD-SSDOTTSWSA-M

How to Prepare Stock Solution?

Concentration Volume Mass
🧮 Molarity Calculator

Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 125 mg/mL (605.82 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.