SMILES:
CC1=C(SC(=N1)NC(=O)N2CCCC2C(=O)N)C3=CC(=NC=C3)C(C)(C)C(F)(F)F
Chemical Structure
Check the
Alpelisib (BYL719)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | (2S)-1-N-[4-methyl-5-[2-(1,1,1-trifluoro-2-methylpropan-2-yl)-4-pyridinyl]-1,3-thiazol-2-yl]pyrrolidine-1,2-dicarboxamide | |
|---|---|---|
| CAS Number | 1217486-61-7 | |
| Molecular Formula |
C19H22F3N5O2S |
|
| Molecular Weight (MW) | 441.47 | |
| SMILES | CC1=C(SC(=N1)NC(=O)N2CCCC2C(=O)N)C3=CC(=NC=C3)C(C)(C)C(F)(F)F | |
| InChIKey | STUWGJZDJHPWGZ-LBPRGKRZSA-N |
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
88 mg/mL
(199.33 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
88 mg/mL
(199.33 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 2 mg/mL |
| Water | Insoluble |
| DMSO |
88 mg/mL
(199.33 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 2 mg/mL |
| Water | Insoluble |
| DMSO |
88 mg/mL
(199.33 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
88 mg/mL
(199.33 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 59 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
- Alpelisib (BYL719) Mechanism of Action: PI3Kα Inhibition in Breast Cancer Cell Research
- Alpelisib (BYL719) Clinical Trials
- Alpelisib (BYL719): Selectivity & Specificity
- Alpelisib (BYL719) Working Concentration | Cell Culture | Treatment
- Alpelisib (BYL719) Solubility in DMSO
- Alpelisib (BYL719) Stock Solution
- Alpelisib (BYL719) Storage
- Alpelisib (BYL719) Stability
- Alpelisib (BYL719) Combination Database
- Alpelisib (BYL719) Molecular Weight
- Alpelisib (BYL719) CAS Number
- Alpelisib (BYL719) Chemical Structure (2D and 3D)
- Alpelisib (BYL719) IC50 for Cell-based and Cell-free Assays
- Alpelisib (BYL719) Sigma (AMBH303C46DC)? Try a better option.
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- Alpelisib (BYL719) SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.