Cell-free Assays (IC50/Ki) for Alpelisib (BYL719)

Key TargetIC50 (Cell-free)DescriptionReference
mTOR >10 μM Biochemical assay Download PDF

Cell-based Assay (IC50) for Alpelisib (BYL719)

Cell TypeIC50 (Cell-based)DescriptionReference
LM-LECs 4.72 nM xCELLigence system RTCA SP; dose–response curve function available in the xCELLigence software Version 2.0 Download PDF
CaSki 1.3 μM Impedance-based proliferation assay, calculated from dose-response curves using nonlinear regression with a two-parameter log-logistic model. Download PDF
C33A 1.5 μM Impedance-based proliferation assay, calculated from dose-response curves using nonlinear regression with a two-parameter log-logistic model. Download PDF
SNU-17 15 μM Impedance-based proliferation assay, calculated from dose-response curves using nonlinear regression with a two-parameter log-logistic model. Download PDF
ME180 5.6 μM Impedance-based proliferation assay, calculated from dose-response curves using nonlinear regression with a two-parameter log-logistic model. Download PDF
Check the Alpelisib (BYL719) product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

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