CAS No. 29908-03-0

Batch: Purity:99.09
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Ademetionine (S-Adenosylmethionine) Chemical Structure
Chemical Structure
Check the Ademetionine (S-Adenosylmethionine) product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name (2S)-2-amino-4-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl-methylsulfonio]butanoate
CAS Number 29908-03-0
Molecular Formula

C15H22N6O5S
Molecular Weight (MW) 398.44
SMILES C[S+](CCC(C(=O)[O-])N)CC1C(C(C(O1)N2C=NC3=C(N=CN=C32)N)O)O
InChIKey MEFKEPWMEQBLKI-AIRLBKTGSA-N

Ordering Information

Biological Activity

Ademetionine (S-Adenosylmethionine) is a primary biological methyl donor involved in transmethylation, transsulfuration, and aminopropylation pathways. It serves as a substrate for methyltransferases and a precursor in glutathione and polyamine synthesis. By modulating mitochondrial function and cellular antioxidant defenses, ademetionine reduces oxidative stress and supports hepatic cell survival and metabolic homeostasis.

Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 80 mg/mL (200.78 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 80 mg/mL
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.