Molecular Weight: 273.19 g/mol

Adefovir Chemical Structure
Chemical Structure
Check the Adefovir product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
5%TFA 6.04 mg/mL
Water 0.1 mg/mL
DMSO Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

Chemical Information

IUPAC Name 2-(6-aminopurin-9-yl)ethoxymethylphosphonic acid
CAS Number 106941-25-7
Molecular Formula

C8H12N5O4P
Molecular Weight (MW) 273.19
SMILES C1=NC(=C2C(=N1)N(C=N2)CCOCP(=O)(O)O)N
InChIKey SUPKOOSCJHTBAH-UHFFFAOYSA-N

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Note: Technical data last updated: Sep 1, 2026.