CAS No. 89796-99-6
Batch:
Purity:99.83
Chemical Structure
Check the
Aceclofenac
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 89796-99-6 | |
|---|---|---|
| Molecular Formula |
C16H13Cl2NO4 |
|
| Molecular Weight (MW) | 354.18 | |
| SMILES | C1=CC=C(C(=C1)CC(=O)OCC(=O)O)NC2=C(C=CC=C2Cl)Cl |
Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) that acts as an inhibitor of cyclooxygenase enzymes to exert anti-inflammatory and analgesic properties. Following intracellular biotransformation into diclofenac, aceclofenac effectively suppresses prostaglandin E2 synthesis within COX-mediated inflammatory signaling pathways. Consequently, this pathway inhibition decreases proinflammatory cytokine expression, prevents extracellular matrix breakdown, and attenuates local inflammatory tissue responses in synovial structures. [1]
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Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
70 mg/mL
(197.63 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.