SMILES:

CC(C)C1=CC=CC=C1SC2=C(C=C(/C=C/C(=O)N3CCN(CC3)C(C)=O)C=C2)[N+]([O-])=O
A286982 Chemical Structure
Chemical Structure
Check the A286982 product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name (E)-1-(4-acetylpiperazin-1-yl)-3-[3-nitro-4-(2-propan-2-ylphenyl)sulfanylphenyl]prop-2-en-1-one
CAS Number 280749-17-9
Molecular Formula

C24H27N3O4S
Molecular Weight (MW) 453.55
SMILES CC(C)C1=CC=CC=C1SC2=C(C=C(/C=C/C(=O)N3CCN(CC3)C(C)=O)C=C2)[N+]([O-])=O
InChIKey HTGGAYLWTDOFDK-PKNBQFBNSA-N

How to Prepare Stock Solution?

Concentration Volume Mass
🧮 Molarity Calculator

Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 90 mg/mL (198.43 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 11 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.