Clinical Trials

Numerous clinical trials spanning Early Phase I through Phase IV evaluate vincristine sulfate in pediatric oncologic conditions and hematologic malignancies, including B-cell acute lymphoblastic leukemia, non-Hodgkin lymphoma, peripheral T-cell lymphoma, and advanced solid tumors. Driven largely by academic and cooperative sponsors—such as the National Cancer Institute, Children's Oncology Group, and St. Jude Children's Research Hospital—these studies investigate pharmacokinetic profiles and multi-agent therapeutic strategies. Across recruiting, active not recruiting, completed, and withdrawn protocols, multiple clinical trials reflect the compound's broad integration into cancer treatment regimens.

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT07220187 NOT_YET_RECRUITING
Richter Syndrome; Transformed Chronic Lymphocytic Leukemia to Diffuse Large B-Cell Lymphoma; Transformed Small Lymphocytic Lymphoma to Diffuse Large B-Cell Lymphoma
SWOG Cancer Research Network
2026-08-31 PHASE3
NCT07072585 NOT_YET_RECRUITING
Stage II T Lymphoblastic Leukemia/Lymphoma; Stage III T Lymphoblastic Leukemia/Lymphoma; Stage IV T Lymphoblastic Leukemia/Lymphoma; T Acute Lymphoblastic Leukemia; T Lymphoblastic Lymphoma
Children's Oncology Group
2026-08-28 PHASE2; PHASE3
NCT04681417 RECRUITING
Retinoblastoma
Institut Curie
2021-03-25 PHASE2; PHASE3
NCT07724457 NOT_YET_RECRUITING
Recurrent Burkitt Lymphoma; Recurrent High Grade B-Cell Lymphoma With MYC and BCL2 Rearrangements; Refractory Burkitt Lymphoma; Refractory High Grade B-Cell Lymphoma With MYC and BCL2 Rearrangements
National Cancer Institute (NCI)
2026-10-30 PHASE2; PHASE3
NCT07387926 RECRUITING
Acute Lymphoblastic Leukemia; Leukemia, Lymphoblastic, Acute, Philadelphia-Positive; Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia
Novartis Pharmaceuticals
2026-07-05 PHASE1; PHASE2
NCT04307576 RECRUITING
Leukemia, Acute Lymphoblastic
Mats Heyman
2020-07-13 PHASE3
NCT06947967 RECRUITING
Lymphoma, T-Cell, Peripheral
Chipscreen Biosciences, Ltd.
2025-08-12 PHASE3
NCT07321912 RECRUITING
Osteosarcoma; Ewing Sarcoma
Milton S. Hershey Medical Center
2026-06-05 PHASE2
NCT07662928 NOT_YET_RECRUITING
Adult Burkitt Lymphoma
AIDS Malignancy Consortium
2026-09-17 PHASE2
NCT05675410 RECRUITING
Lugano Classification Limited Stage Hodgkin Lymphoma AJCC v8
National Cancer Institute (NCI)
2023-05-11 PHASE3
NCT05605899 ACTIVE_NOT_RECRUITING
High-risk Large B-cell Lymphoma (LBCL)
Kite, A Gilead Company
2023-02-10 PHASE3
NCT06401330 RECRUITING
Stage I Mixed Cell Type Kidney Wilms Tumor; Stage II Mixed Cell Type Kidney Wilms Tumor; Stage III Mixed Cell Type Kidney Wilms Tumor; Stage IV Mixed Cell Type Kidney Wilms Tumor
Children's Oncology Group
2025-04-15 PHASE3
NCT07712588 NOT_YET_RECRUITING
Diffuse Large B-Cell Lymphoma (DLBCL)
Dizal Pharmaceuticals
2026-09 PHASE2; PHASE3
NCT07654426 RECRUITING
Diffuse Large B-cell Lymphoma (DLBCL); Cardiotoxicity; Lymphoma
Beth Israel Deaconess Medical Center
2026-08-31 PHASE2
NCT04166409 RECRUITING
Low Grade Astrocytoma; Low Grade Glioma; Metastatic Low Grade Astrocytoma; Metastatic Low Grade Glioma; WHO Grade 1 Glioma; WHO Grade 2 Glioma
National Cancer Institute (NCI)
2020-01-31 PHASE3
NCT07431060 RECRUITING
Langerhans Cell Histiocytosis (LCH)
West China Second University Hospital
2026-02-13
NCT07227584 RECRUITING
Acute Lymphoblastic Leukemia; Philadelphia Chromosome-Negative Lymphoblastic Leukemia; Acute Lymphoblastic Leukemia (ALL); Leukemia
Dana-Farber Cancer Institute
2026-04-03 PHASE2
NCT07719855 NOT_YET_RECRUITING
Follicular Lymphoma ( FL)
Ruijin Hospital
2026-07 PHASE3
NCT06721689 RECRUITING
Refractory Solid Tumors; Relapsed Solid Tumors; Relapsed Neuroblastoma; Refractory Neuroblastoma; Relapsed Rhabdomyosarcoma; Refractory Rhabdomyosarcoma
Theodore Laetsch
2025-03-23 PHASE1; PHASE2
NCT06172296 RECRUITING
Ganglioneuroblastoma, Nodular; Neuroblastoma
National Cancer Institute (NCI)
2024-04-19 PHASE3
NCT07493148 RECRUITING
Diffuse Large B-Cell Lymphoma (DLBCL)
Ou Bai, MD/PHD
2026-04-30 PHASE2
NCT00887146 ACTIVE_NOT_RECRUITING
Brain and Central Nervous System Tumors
Alliance for Clinical Trials in Oncology
2009-09 PHASE3
NCT06528496 RECRUITING
High-risk Neuroblastoma; Neuroblastoma; Childhood Neuroblastoma
Memorial Sloan Kettering Cancer Center
2024-07-22 PHASE2
NCT06564038 RECRUITING
Chronic Lymphocytic Leukaemia; Small Lymphocytic Lymphoma; Mantle-cell Lymphoma; Large B-cell Lymphoma; B-cell Non-Hodgkin Lymphoma
AstraZeneca
2025-01-30 PHASE1; PHASE2
NCT05848765 RECRUITING
Relapsed Follicular Lymphoma; Refractory Follicular Lymphoma
University of Birmingham
2023-09-04 PHASE2
NCT06188676 RECRUITING
Primary Mediastinal Lymphoma
National Research Center for Hematology, Russia
2022-04-01 PHASE3
NCT06647953 RECRUITING
Pleuropulmonary Blastoma
Children's Oncology Group
2025-03-21 PHASE3
NCT06918431 RECRUITING
B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative; Lymphoblastic Lymphoma
City of Hope Medical Center
2025-10-10 PHASE2
NCT07301138 NOT_YET_RECRUITING
Acute Lymphoblastic Leukemia
Ruijin Hospital
2025-12-15 PHASE2
NCT04199026 RECRUITING
Metastatic Sarcoma; Recurrent Sarcoma; Resectable Sarcoma
M.D. Anderson Cancer Center
2025-02-25
NCT06220032 RECRUITING
DLBCL - Diffuse Large B Cell Lymphoma
Stichting Hemato-Oncologie voor Volwassenen Nederland
2024-08-15 PHASE3
NCT04884035 ACTIVE_NOT_RECRUITING
Lymphoma, B-Cell
Celgene
2021-09-15 PHASE1
NCT07258680 ENROLLING_BY_INVITATION
Peripheral T-cell Lymphoma
N.N. Petrov National Medical Research Center of Oncology
2013-10 PHASE3
NCT06709495 RECRUITING
Sarcoma; Sarcoma, Ewing; Desmoplastic Small Round Cell Tumor; Refractory Sarcoma; Osteosarcoma; Rhabdomyosarcoma
David S Shulman, MD
2025-01-27 PHASE1; PHASE2
NCT01878617 ACTIVE_NOT_RECRUITING
Medulloblastoma
St. Jude Children's Research Hospital
2013-06-23 PHASE2
NCT07224100 RECRUITING
B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1; B Lymphoblastic Leukemia/Lymphoma With t(9;22)(q34.1;q11.2); BCR-ABL1; Lymphoblastic Lymphoma
University of Washington
2026-03-30 PHASE2
NCT05888493 ACTIVE_NOT_RECRUITING
Follicular Lymphoma (FL)
Novartis Pharmaceuticals
2023-10-02 PHASE3
NCT03643276 RECRUITING
Acute Lymphoblastic Leukemia, Pediatric
Martin Schrappe
2018-07-15 PHASE3
NCT04546399 RECRUITING
Down Syndrome; Recurrent B Acute Lymphoblastic Leukemia
National Cancer Institute (NCI)
2020-12-17 PHASE2
NCT05389423 RECRUITING
Diffuse Large Cell Lymphoma; Non-Hodgkin Lymphoma; Burkitt Lymphoma; Plasmablastic Lymphoma; B-Cell Neoplasm
National Cancer Institute (NCI)
2023-06-27 PHASE1
NCT07643103 NOT_YET_RECRUITING
Ph- Acute Lymphoblastic Leukemia (Ph-ALL)
Institute of Hematology & Blood Diseases Hospital, China
2026-06-12 PHASE2
NCT03984448 ACTIVE_NOT_RECRUITING
Diffuse Large B-Cell Lymphoma; Diffuse Large B-Cell Lymphoma, Not Otherwise Specified; Double-Expressor Lymphoma; EBV-Positive Diffuse Large B-Cell Lymphoma, Not Otherwise Specified; High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements; High Grade B-Cell Lymphoma, Not Otherwise Specified; Neoplastic Cells With Double Expression of MYC and BCL2 Proteins Present; Transformed Indolent B-Cell Non-Hodgkin Lymphoma to Diffuse Large B-Cell Lymphoma
National Cancer Institute (NCI)
2019-10-22 PHASE2; PHASE3
NCT05504291 RECRUITING
Bilateral Retinoblastoma; Childhood Intraocular Retinoblastoma; Group D Retinoblastoma; Stage I Retinoblastoma; Unilateral Retinoblastoma
Children's Oncology Group
2022-11-04 PHASE2
NCT02724579 ACTIVE_NOT_RECRUITING
Medulloblastoma
Children's Oncology Group
2017-11-17 PHASE2
NCT06091254 RECRUITING
Follicular Lymphoma (FL)
Regeneron Pharmaceuticals
2023-12-12 PHASE3
NCT07676175 NOT_YET_RECRUITING
Previously Untreated Peripheral T-Cell Lymphoma
BeBetter Med Inc
2026-07-01 PHASE2
NCT03871257 ACTIVE_NOT_RECRUITING
Low Grade Glioma; Neurofibromatosis Type 1; Visual Pathway Glioma
National Cancer Institute (NCI)
2020-01-15 PHASE3
NCT07535762 NOT_YET_RECRUITING
Peripheral T-Cell Lymphoma (PTCL NOS); Nodal T-follicular Helper Cell Lymphoma; Anaplastic Large Cell Lymphoma (ALCL) (ALK-1 Negative)
Shanghai Jiao Tong University School of Medicine
2026-03-30 PHASE2
NCT01371630 RECRUITING
B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1; B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative; Burkitt-Like Lymphoma With 11q Aberration; High Grade B-Cell Lymphoma With MYC and BCL2 and/or BCL6 Rearrangements; High Grade B-Cell Lymphoma, Not Otherwise Specified; Recurrent B Acute Lymphoblastic Leukemia; Recurrent Burkitt Lymphoma; Refractory B Acute Lymphoblastic Leukemia; Refractory Burkitt Lymphoma
M.D. Anderson Cancer Center
2011-08-26 PHASE1; PHASE2
NCT01424982 ACTIVE_NOT_RECRUITING
Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Acute Lymphoblastic Leukemia; Adult Acute Lymphoblastic Leukemia in Complete Remission; B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1; Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Philadelphia Chromosome Positive; Untreated Adult Acute Lymphoblastic Leukemia
M.D. Anderson Cancer Center
2011-10-05 PHASE2
NCT06692452 WITHDRAWN
Lymphoma; Peripheral T Cell Lymphoma; Angioimmunoblastic T-cell Lymphoma; Enteropathy-Associated T-Cell Lymphoma; Monomorphic Epitheliotropic Intestinal T-Cell Lymphoma
Eric Jacobsen, MD
2024-12-24 PHASE2
NCT03914625 ACTIVE_NOT_RECRUITING
B Acute Lymphoblastic Leukemia; B Lymphoblastic Lymphoma; Down Syndrome
National Cancer Institute (NCI)
2019-07-03 PHASE3
NCT07444710 NOT_YET_RECRUITING
Ann Arbor Stage II Mantle Cell Lymphoma; Ann Arbor Stage III Mantle Cell Lymphoma; Ann Arbor Stage IV Mantle Cell Lymphoma
National Cancer Institute (NCI)
2026-10-30 PHASE1
NCT04542824 ACTIVE_NOT_RECRUITING
Diffuse Large B Cell Lymphoma; High-grade B-cell Lymphoma; Primary Mediastinal Large B Cell Lymphoma; Follicular Lymphoma; Marginal Zone Lymphoma; Small Lymphocytic Lymphoma
Genmab
2020-08-20 PHASE1; PHASE2
NCT03136146 RECRUITING
Recurrent Acute Lymphoblastic Leukemia; Recurrent Adult Lymphoblastic Lymphoma; Recurrent Burkitt Leukemia; Recurrent Burkitt Lymphoma; Recurrent Childhood Lymphoblastic Lymphoma; Recurrent High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements; Refractory Acute Lymphoblastic Leukemia; Refractory Burkitt Leukemia; Refractory Burkitt Lymphoma; Refractory High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements; Refractory Lymphoblastic Lymphoma
M.D. Anderson Cancer Center
2017-08-09 PHASE2
NCT06630091 RECRUITING
Peripheral T Cell Lymphoma
M.D. Anderson Cancer Center
2025-02-21 PHASE2
NCT04322318 RECRUITING
Anaplastic Kidney Wilms Tumor; Recurrent Kidney Wilms Tumor; Stage II Kidney Wilms Tumor; Stage III Kidney Wilms Tumor; Stage IV Kidney Wilms Tumor
Children's Oncology Group
2020-10-19 PHASE2
NCT05279300 SUSPENDED
Advanced Solid Tumor; Advanced Lymphoma
CStone Pharmaceuticals
2022-03-28 PHASE1
NCT04301076 RECRUITING
Acute Adult T-Cell Leukemia/Lymphoma; Adult T-Cell Leukemia/Lymphoma; Chronic Adult T-Cell Leukemia/Lymphoma; HTLV-1 Infection
National Cancer Institute (NCI)
2021-08-31 PHASE1
NCT05578976 ACTIVE_NOT_RECRUITING
Diffuse Large B-Cell Lymphoma
Genmab
2023-02-08 PHASE3
NCT06421948 RECRUITING
Peripheral T-cell Lymphoma
Yanyan Liu
2024-05-25 PHASE1; PHASE2
NCT04803201 RECRUITING
Angioimmunoblastic T-cell Lymphoma; Enteropathy-Associated T-Cell Lymphoma; Follicular T-Cell Lymphoma; Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma; Monomorphic Epitheliotropic Intestinal T-Cell Lymphoma; Nodal Peripheral T-Cell Lymphoma With TFH Phenotype; Peripheral T-Cell Lymphoma, Not Otherwise Specified
Alliance for Clinical Trials in Oncology
2021-10-08 PHASE2
NCT07092306 NOT_YET_RECRUITING
Ewing's Sarcoma
Tang Xiaodong
2025-08-10 PHASE2
NCT07081022 ACTIVE_NOT_RECRUITING
B-cell Non-Hodgkin's Lymphoma
Shanghai Junshi Bioscience Co., Ltd.
2025-08-17 PHASE2
NCT03533582 ACTIVE_NOT_RECRUITING
Childhood Hepatocellular Carcinoma; Childhood Malignant Liver Neoplasm; Fibrolamellar Carcinoma; Hepatoblastoma; Hepatocellular Malignant Neoplasm, Not Otherwise Specified
Children's Oncology Group
2018-05-24 PHASE3
NCT04478292 RECRUITING
Hepatoblastoma
Shanghai Children's Medical Center
2021-03-01 PHASE3
NCT03710772 ACTIVE_NOT_RECRUITING
Mantle Cell Lymphoma
M.D. Anderson Cancer Center
2019-05-01 PHASE2
NCT01837862 ACTIVE_NOT_RECRUITING
Pilomyxoid Astrocytoma; Pilocytic Astrocytoma; Glioma, Astrocytic; Optic Nerve Glioma; Pleomorphic Xanthoastrocytoma; Glioblastoma Multiforme; Anaplastic Astrocytoma; Gliosarcoma; Diffuse Intrinsic Pontine Glioma; DIPG; Low-grade Glioma; Brainstem Glioma
Julie Krystal
2013-10-22 PHASE1; PHASE2
NCT04529772 ACTIVE_NOT_RECRUITING
Diffuse Large B-Cell Lymphoma
Acerta Pharma BV
2020-10-08 PHASE3
NCT04978584 ACTIVE_NOT_RECRUITING
Diffuse Large B-Cell Lymphoma
M.D. Anderson Cancer Center
2022-03-03 PHASE2
NCT03755804 ACTIVE_NOT_RECRUITING
Hodgkin Lymphoma
St. Jude Children's Research Hospital
2018-12-12 PHASE2
NCT04759586 ACTIVE_NOT_RECRUITING
Primary Mediastinal Large B-Cell Lymphoma
National Cancer Institute (NCI)
2021-10-05 PHASE3
NCT05681260 RECRUITING
T-cell Lymphoblastic Lymphoma
Children's Cancer Group, China
2023-02-06 PHASE3
NCT02981628 ACTIVE_NOT_RECRUITING
Recurrent B Acute Lymphoblastic Leukemia; Recurrent B Lymphoblastic Lymphoma; Refractory B Acute Lymphoblastic Leukemia; Refractory B Lymphoblastic Lymphoma
Children's Oncology Group
2017-06-19 PHASE2
NCT04638790 RECRUITING
Hodgkin Lymphoma, Adult
State Budgetary Healthcare Institution, National Medical Surgical Center N.A. N.I. Pirogov, Ministry of Health of Russia
2020-02-01 PHASE3
NCT04890093 SUSPENDED
Sarcoma, Ewing; Rhabdomyosarcoma
National Cancer Institute (NCI)
2024-10-31 PHASE1; PHASE2
NCT06387121 RECRUITING
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Institute of Hematology & Blood Diseases Hospital, China
2024-04-02 PHASE2
NCT06207123 RECRUITING
Acute Leukemia; Lymphoblastic Leukemia; Lymphoblastic Lymphoma
University of Chicago
2024-09-13 PHASE1; PHASE2
NCT01871766 ACTIVE_NOT_RECRUITING
Rhabdomyosarcoma
St. Jude Children's Research Hospital
2013-12-04 PHASE2
NCT02877303 RECRUITING
B Acute Lymphoblastic Leukemia; B Lymphoblastic Lymphoma
M.D. Anderson Cancer Center
2016-11-01 PHASE2
NCT00501826 RECRUITING
T Acute Lymphoblastic Leukemia; T Lymphoblastic Lymphoma
M.D. Anderson Cancer Center
2007-07-11 PHASE2
NCT05455697 ACTIVE_NOT_RECRUITING
Diffuse Large B-Cell Lymphoma; Grade 3b Follicular Lymphoma; High Grade B-Cell Lymphoma
University of Washington
2023-01-26 PHASE1; PHASE2
NCT06977711 RECRUITING
Diffuse Large B-cell Lymphoma
The University of Texas Health Science Center at San Antonio
2025-06-20 PHASE1
NCT03117751 ACTIVE_NOT_RECRUITING
Acute Lymphoblastic Leukemia; Acute Lymphoblastic Lymphoma
St. Jude Children's Research Hospital
2017-03-29 PHASE2; PHASE3
NCT06210750 WITHDRAWN
T Acute Lymphoblastic Leukemia; T Lymphoblastic Lymphoma
National Cancer Institute (NCI)
2024-08-09 PHASE2
NCT05521087 WITHDRAWN
Acute Leukemias; Acute Myeloid Leukemia; Acute Lymphoblastic Leukemia; Acute Leukemia of Ambiguous Lineage
Janssen Research & Development, LLC
2025-12-26 PHASE1
NCT06514313 RECRUITING
Soft Tissue Sarcoma
Yizhuo Zhang
2024-07-03 PHASE2
NCT04388839 ACTIVE_NOT_RECRUITING
Rhabdomyosarcoma
H. Lee Moffitt Cancer Center and Research Institute
2020-12-29 PHASE2
NCT06005870 RECRUITING
Diffuse Large B Cell Lymphoma
Huazhong University of Science and Technology
2022-11-26 PHASE2
NCT05457829 RECRUITING
Rhabdomyosarcoma, Child
Sun Yat-sen University
2023-12-30 PHASE2
NCT04994132 ACTIVE_NOT_RECRUITING
Alveolar Rhabdomyosarcoma; Botryoid-Type Embryonal Rhabdomyosarcoma; Embryonal Rhabdomyosarcoma; Metastatic Embryonal Rhabdomyosarcoma; Metastatic Rhabdomyosarcoma; Solid Alveolar Rhabdomyosarcoma; Spindle Cell Rhabdomyosarcoma; Spindle Cell/Sclerosing Rhabdomyosarcoma
Children's Oncology Group
2021-09-14 PHASE3
NCT06820957 ACTIVE_NOT_RECRUITING
CIC-Rearranged Sarcoma; Metastatic Ewing Sarcoma; Metastatic High Grade Sarcoma; Metastatic Undifferentiated Round Cell Sarcoma; Metastatic Undifferentiated Sarcoma, Not Otherwise Specified; Round Cell Sarcoma With EWSR1-non-ETS Fusion; Sarcoma With BCOR Genetic Alterations
Children's Oncology Group
2025-11-10 PHASE2; PHASE3
NCT04850495 ACTIVE_NOT_RECRUITING
Diffuse Large B-Cell Lymphoma; Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma; Transformed Marginal Zone Lymphoma to Diffuse Large B-Cell Lymphoma
Yazeed Sawalha
2021-11-16 PHASE1
NCT05351346 UNKNOWN
Diffuse Large B Cell Lymphoma
Ruijin Hospital
2022-06-01 PHASE3
NCT03758989 RECRUITING
DLBCL
University of Rochester
2019-05-08 PHASE2
NCT06701344 NOT_YET_RECRUITING
Enteropathy Associated T Cell Lymphoma
Ruijin Hospital
2024-12-04 PHASE2
NCT06700798 RECRUITING
Marginal Zone Lymphoma(MZL)
Fei Li
2024-12-01 PHASE2
NCT05934097 WITHDRAWN
Diffuse Large B Cell Lymphoma; Transformed Indolent Non-Hodgkin's Lymphoma; Follicular Lymphoma; Mantle Cell Lymphoma; Marginal Zone Lymphoma
Fate Therapeutics
2022-12 PHASE1
NCT05453500 ACTIVE_NOT_RECRUITING
B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative
University of Washington
2023-03-27 PHASE2
NCT02723994 COMPLETED
Leukemia
Incyte Corporation
2016-09-30 PHASE2
NCT03749018 ACTIVE_NOT_RECRUITING
Aggressive Non-Hodgkin Lymphoma; Ann Arbor Stage I Primary Mediastinal (Thymic) Large B-Cell Cell Lymphoma; Ann Arbor Stage II B-Cell Non-Hodgkin Lymphoma; Ann Arbor Stage II Primary Mediastinal (Thymic) Large B-Cell Cell Lymphoma; Ann Arbor Stage III B-Cell Non-Hodgkin Lymphoma; Ann Arbor Stage III Primary Mediastinal (Thymic) Large B-Cell Cell Lymphoma; Ann Arbor Stage IV B-Cell Non-Hodgkin Lymphoma; Ann Arbor Stage IV Primary Mediastinal (Thymic) Large B-Cell Cell Lymphoma; Diffuse Large B-Cell Lymphoma; High Grade B-Cell Lymphoma With MYC and BCL2 and/or BCL6 Rearrangements; High Grade B-Cell Lymphoma, Not Otherwise Specified; Indolent Non-Hodgkin Lymphoma; Mediastinal B-Cell Lymphoma, Unclassifiable, With Features Intermediate Between Diffuse Large B-Cell Lymphoma and Classic Hodgkin Lymphoma; Transformed Non-Hodgkin Lymphoma
David Bond, MD
2019-01-02 PHASE2
NCT06921044 NOT_YET_RECRUITING
Diffuse Large B-Cell Lymphoma
Xiaohui He
2025-04-16 PHASE2
NCT03269669 ACTIVE_NOT_RECRUITING
Grade 1 Follicular Lymphoma; Grade 2 Follicular Lymphoma; Grade 3a Follicular Lymphoma; Recurrent Follicular Lymphoma; Refractory Follicular Lymphoma
National Cancer Institute (NCI)
2018-01-23 PHASE2
NCT06710821 NOT_YET_RECRUITING
Solid Tumor Cancer
Yizhuo Zhang
2024-12-01 PHASE1
NCT01464606 ACTIVE_NOT_RECRUITING
Pleuropulmonary Blastoma
Children's Hospitals and Clinics of Minnesota
2009-12-22
NCT04835870 UNKNOWN
Non-GCB/ABC Diffuse Large B-Cell Lymphoma
The First Affiliated Hospital of Soochow University
2021-04-01 PHASE2
NCT05422066 UNKNOWN
DLBCL Germinal Center B-Cell Type
Li Zhiming
2022-07-26 PHASE2
NCT05051891 COMPLETED
Treatment-naїve Mantle Cell Lymphoma
Beijing InnoCare Pharma Tech Co., Ltd.
2021-12-22 PHASE3
NCT06760117 RECRUITING
Pediatric Solid Tumor
Sun Yat-sen University
2022-01-01 PHASE1
NCT05270057 ACTIVE_NOT_RECRUITING
B-cell Lymphoma; Burkitt Lymphoma
Medical College of Wisconsin
2023-01-26 PHASE1
NCT05201248 ACTIVE_NOT_RECRUITING
B-Cell Non-Hodgkin Lymphoma
Genmab
2022-03-10 PHASE1; PHASE2
NCT05238064 UNKNOWN
PI3Kδ Inhibitor; Parsaclisib; CHOP; PTCL
Fudan University
2022-03 PHASE1; PHASE2
NCT03399747 UNKNOWN
Diffuse Large B-cell Lymphoma
Asan Medical Center
2016-12-07 PHASE2
NCT04432714 RECRUITING
DLBCL; Untreated; MYC Gene Rearrangement
The First Affiliated Hospital with Nanjing Medical University
2020-06-09 PHASE1; PHASE2
NCT05458180 UNKNOWN
Peripheral T-cell Lymphoma
Tianjin Medical University Cancer Institute and Hospital
2022-07-07 PHASE1
NCT02881086 COMPLETED
Acute Lymphoblastic Leukemia; Lymphoblastic Lymphoma
Goethe University
2016-08 PHASE3
NCT03220022 ACTIVE_NOT_RECRUITING
AIDS-Related Lymphoma; Ann Arbor Stage II Diffuse Large B-Cell Lymphoma; Ann Arbor Stage III Diffuse Large B-Cell Lymphoma; Ann Arbor Stage IV Diffuse Large B-Cell Lymphoma
National Cancer Institute (NCI)
2018-03-16 PHASE1
NCT02911142 ACTIVE_NOT_RECRUITING
Primary Effusion Lymphoma; B-Cell Neoplasm
National Cancer Institute (NCI)
2017-07-03 PHASE1; PHASE2
NCT05656222 WITHDRAWN
Objective Response; Overall Survival
Peking University People's Hospital
2021-08-01
NCT04980222 ACTIVE_NOT_RECRUITING
Lymphoma
Hoffmann-La Roche
2022-03-22 PHASE2
NCT05620862 UNKNOWN
Pediatric Solid Tumor
Sun Yat-sen University
2022-10-25 PHASE1
NCT05887726 UNKNOWN
Diffuse Large B Cell Lymphoma
Liaoning Cancer Hospital & Institute
2023-08-01 PHASE2
NCT05990985 UNKNOWN
Diffuse Large B-cell Lymphoma
The First Hospital of Jilin University
2023-09-01
NCT00878254 COMPLETED
Mantle-Cell Lymphoma
University of Miami
2009-03-25 PHASE2
NCT03505762 ACTIVE_NOT_RECRUITING
B-Cell Non-Hodgkin Lymphoma
Wake Forest University Health Sciences
2018-07-19 PHASE2
NCT04974996 WITHDRAWN
Diffuse Large B-Cell Lymphoma
ADC Therapeutics S.A.
2022-02-01 PHASE1
NCT00390793 COMPLETED
Acute Lymphoblastic Leukemia; BCR-ABL1 Fusion Protein Expression; Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Philadelphia Chromosome Positive; Recurrent Acute Lymphoblastic Leukemia; t(9;22)
M.D. Anderson Cancer Center
2006-09-28 PHASE2
NCT05200312 UNKNOWN
Non Hodgkin Lymphoma; Diffuse Large B Cell Lymphoma
The First Affiliated Hospital with Nanjing Medical University
2022-02-01 PHASE2
NCT04922567 RECRUITING
Peripheral T-Cell Lymphoma; Lenalidomide; CHOP
Second Affiliated Hospital, Zhejiang University, School of Medicine
2021-04-01 PHASE2
NCT04214626 COMPLETED
Diffuse Large B Cell Lymphoma
Henan Cancer Hospital
2020-01-05 PHASE2
NCT04842487 UNKNOWN
DLBCL
Sun Yat-sen University
2021-04-10 PHASE2
NCT04914741 UNKNOWN
Diffuse Large B Cell Lymphoma; High-grade B-cell Lymphoma
Peter MacCallum Cancer Centre, Australia
2021-06-29 PHASE1; PHASE2
NCT03817320 ACTIVE_NOT_RECRUITING
ALL, Childhood; Lymphoblastic Lymphoma, Childhood; Lymphoblastic Leukemia, Acute, Childhood
Therapeutic Advances in Childhood Leukemia Consortium
2019-02-12 PHASE1; PHASE2
NCT03677141 COMPLETED
B-cell Non-Hodgkin Lymphoma
Hoffmann-La Roche
2019-03-08 PHASE1; PHASE2
NCT05008224 COMPLETED
Classical Hodgkin Lymphoma
Merck Sharp & Dohme LLC
2021-10-07 PHASE2
NCT02626455 TERMINATED
Lymphoma, Non-Hodgkin
Bayer
2016-01-06 PHASE3
NCT05777369 UNKNOWN
Diffuse Large B-cell Lymphoma
The First Affiliated Hospital with Nanjing Medical University
2023-03
NCT02348216 COMPLETED
Refractory Diffuse Large B Cell Lymphoma (DLBCL); Relapsed Diffuse Large B-Cell Lymphoma; Transformed Follicular Lymphoma (TFL); Primary Mediastinal B-cell Lymphoma (PMBCL); High Grade B-cell Lymphoma (HGBCL)
Kite, A Gilead Company
2015-04-21 PHASE1; PHASE2
NCT03864419 TERMINATED
Burkitt Lymphoma; KSHV-associated Multicentric Castleman Disease; Diffuse Large B-Cell Lymphoma
Fred Hutchinson Cancer Center
2019-10-24 PHASE1
NCT04659421 COMPLETED
Low-grade Glioma; Pediatric Brain Tumor
Beijing Sanbo Brain Hospital
2020-11-03 PHASE2
NCT04773366 UNKNOWN
Langerhans Cell Histiocytosis
Shanghai Children's Medical Center
2018-07-01 PHASE3
NCT02567435 ACTIVE_NOT_RECRUITING
Alveolar Rhabdomyosarcoma; Botryoid-Type Embryonal Rhabdomyosarcoma; Embryonal Rhabdomyosarcoma; Rhabdomyosarcoma; Sclerosing Rhabdomyosarcoma; Spindle Cell Rhabdomyosarcoma
National Cancer Institute (NCI)
2016-06-01 PHASE3
NCT04448834 WITHDRAWN
B-cell Acute Lymphoblastic Leukemia
Dorothy Sipkins, MD, PhD
2022-01 PHASE2
NCT05425654 UNKNOWN
Primary CNS Lymphoma
National Research Center for Hematology, Russia
2021-05-17 PHASE2
NCT04480099 UNKNOWN
Peripheral T-cell Lymphoma
Ruijin Hospital
2020-07-29 PHASE2
NCT05844670 Recruiting
Pediatric Cancer
Moi University|Princess Maxima Center for Pediatric Oncology|Amsterdam UMC location VUmc
2023-04-20 Phase 4
NCT04842318 UNKNOWN
Follicular Lymphoma
Ruijin Hospital
2021-03-01 PHASE4
NCT00596154 COMPLETED
CNS Lymphoma; CNS Brain Cancer; Non-Hodgkin's Lymphoma
Memorial Sloan Kettering Cancer Center
2004-12 PHASE2
NCT02661503 UNKNOWN
Classical Hodgkin Lymphoma
University of Cologne
2016-07 PHASE3
NCT02752815 UNKNOWN
Diffuse Large B-cell Lymphoma
Ruijin Hospital
2016-06-14 PHASE4
NCT02636322 COMPLETED
Diffuse Large B-Cell Lymphoma Unclassifiable
M.D. Anderson Cancer Center
2016-03-29 PHASE2
NCT03991884 COMPLETED
Recurrent B Acute Lymphoblastic Leukemia; Recurrent B Lymphoblastic Lymphoma; Refractory B Acute Lymphoblastic Leukemia; Refractory B Lymphoblastic Lymphoma
University of Washington
2019-09-24 PHASE1
NCT03589326 ACTIVE_NOT_RECRUITING
Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (Ph+ALL)
Takeda
2018-10-04 PHASE3
NCT02398240 COMPLETED
Hodgkin Lymphoma
Mitchell Cairo
2015-05 PHASE2
NCT01974440 COMPLETED
Lymphoma
Janssen Research & Development, LLC
2014-01-31 PHASE3
NCT04660799 COMPLETED
Lymphoma, Large B-Cell, Diffuse
Hoffmann-La Roche
2021-02-24 PHASE2
NCT02553460 ACTIVE_NOT_RECRUITING
Acute Lymphoblastic Leukemia
St. Jude Children's Research Hospital
2016-01-29 PHASE1; PHASE2
NCT03003520 COMPLETED
Lymphoma, Large B-Cell, Diffuse
Celgene
2017-02-28 PHASE2
NCT01925131 COMPLETED
Acute Leukemias of Ambiguous Lineage; B-cell Adult Acute Lymphoblastic Leukemia; Philadelphia Chromosome Positive Adult Precursor Acute Lymphoblastic Leukemia; Recurrent Adult Acute Lymphoblastic Leukemia; Recurrent Adult Burkitt Lymphoma
SWOG Cancer Research Network
2014-06-13 PHASE1
NCT04448834 Withdrawn
B-cell Acute Lymphoblastic Leukemia
Dorothy Sipkins MD PhD|Amgen|Acrotech Biopharma Inc.|Duke University
2022-01 Phase 2
NCT02523976 COMPLETED
Acute,Leukemia, Lymphoid
Institute of Hematology & Blood Diseases Hospital, China
2015-08-01 PHASE2
NCT02166463 ACTIVE_NOT_RECRUITING
Ann Arbor Stage IIB Hodgkin Lymphoma; Ann Arbor Stage IIIB Hodgkin Lymphoma; Ann Arbor Stage IVA Hodgkin Lymphoma; Ann Arbor Stage IVB Hodgkin Lymphoma; Childhood Hodgkin Lymphoma; Classic Hodgkin Lymphoma
National Cancer Institute (NCI)
2015-03-19 PHASE3
NCT02918747 UNKNOWN
Lymphoma
Hunan Cancer Hospital
2016-09 PHASE2
NCT02684058 COMPLETED
Diffuse Astrocytoma; Anaplastic Astrocytoma; Astrocytoma; Oligodendroglioma, Childhood; Anaplastic Oligodendroglioma; Glioblastoma; Pilocytic Astrocytoma; Giant Cell Astrocytoma; Pleomorphic Xanthoastrocytoma; Anaplastic Pleomorphic Xanthoastrocytoma; Angiocentric Glioma; Chordoid Glioma of Third Ventricle; Gangliocytoma; Ganglioglioma; Anaplastic Ganglioglioma; Dysplastic Gangliocytoma of Cerebrellum; Desmoplastic Infantile Astrocytoma and Ganglioglioma; Papillary Glioneuronal Tumor; Rosette-forming Glioneurona Tumor; Central Neurocytoma; Extraventricular Neurocytoma; Cerebellar Iponeurocytoma
Novartis Pharmaceuticals
2017-12-28 PHASE2
NCT03349281 COMPLETED
Refractory Acute Lymphoblastic Leukemia; Relapsed Acute Lymphoblastic Leukemia
Julio Barredo, MD
2019-03-25 PHASE1
NCT03792256 COMPLETED
Leukemia, Lymphocytic; Lymphoblastic Lymphoma; T-cell Lymphoma; T-cell Leukemia; Recurrent Disease; Acute Leukemia
Children's Oncology Group
2019-04-11 PHASE1
NCT03564704 UNKNOWN
Leukemia; Leukemia, Acute; Adult Lymphoblastic Lymphoma; Leukemia, Lymphoblastic; Leukemia, T Cell; Adult Acute Lymphoblastic Leukemia; Lymphoblastic Lymphoma; Lymphoblastic Leukemia
Nanfang Hospital, Southern Medical University
2016-02-14 PHASE2; PHASE3
NCT03688633 TERMINATED
Peripheral Neuropathy
University Hospital, Limoges
2019-05-01 PHASE2
NCT00670358 COMPLETED
Lymphoma
Mayo Clinic
2008-08-25 PHASE1; PHASE2
NCT03892330 NOT_YET_RECRUITING
0.5-14 Year Old Children With Nephroblastoma
Shengjing Hospital
2019-06-01 PHASE4
NCT03613428 UNKNOWN
Acute T Cell Leukemia
Sichuan University
2018-12-01 PHASE1; PHASE2
NCT01920932 ACTIVE_NOT_RECRUITING
Stage II Childhood Hodgkin Lymphoma; Stage III Childhood Hodgkin Lymphoma; Stage IV Childhood Hodgkin Lymphoma
St. Jude Children's Research Hospital
2013-08-12 PHASE2
NCT01319981 COMPLETED
Leukemia
M.D. Anderson Cancer Center
2013-03-05 PHASE2
NCT00477412 COMPLETED
Mantle Cell Lymphoma
M.D. Anderson Cancer Center
2007-04-03 PHASE1; PHASE2
NCT03617432 UNKNOWN
Experimental Tumor
Peking University
2018-08-28 PHASE2
NCT00549848 COMPLETED
Acute Lymphoblastic Leukemia
St. Jude Children's Research Hospital
2007-10-29 PHASE3
NCT01542736 COMPLETED
Metastatic Medulloblastoma; High Risk Supratentorial PNET; Metastatic PNET
University of Colorado, Denver
2007-05 PHASE2
NCT02257242 COMPLETED
Lymphoma, Non-Hodgkin; Lymphoma, Follicular; Lymphoma, Mantle-Cell; Lymphoma, Small-Cell; Waldenstrom Macroglobulinemia; Lymphoma, B-Cell, Marginal Zone
Brown University
2017-05-10 PHASE1
NCT04243434 UNKNOWN
Hematologic Diseases
Acrotech Biopharma Inc.
2020-08-15 PHASE1
NCT03268889 UNKNOWN
Peripheral T Cell Lymphoma
The First Affiliated Hospital of Soochow University
2017-06-15
NCT01359592 COMPLETED
Lymphoma
SWOG Cancer Research Network
2011-09 PHASE2
NCT02670616 COMPLETED
Epstein-Barr Virus-positive Diffuse Large B-cell Lymphoma
Samsung Medical Center
2016-05-01 PHASE2
NCT01363128 COMPLETED
Acute Lymphoblastic Leukemia; Adult Acute Lymphoblastic Leukemia in Complete Remission; Burkitt Leukemia; Burkitt Lymphoma; CD20 Positive; Childhood Acute Lymphoblastic Leukemia in Complete Remission; Lymphoblastic Lymphoma
M.D. Anderson Cancer Center
2011-07-12 PHASE2
NCT01856192 ACTIVE_NOT_RECRUITING
Ann Arbor Stage II Diffuse Large B-Cell Lymphoma; Ann Arbor Stage III Diffuse Large B-Cell Lymphoma; Ann Arbor Stage IV Diffuse Large B-Cell Lymphoma
National Cancer Institute (NCI)
2013-08-27 PHASE2
NCT01356680 COMPLETED
Hodgkin Lymphoma
University of Cologne
2012-01-13 PHASE3
NCT03018626 UNKNOWN
Lymphoma, Large B-Cell, Diffuse
Nanfang Hospital, Southern Medical University
2017-07-27 PHASE3
NCT02036489 COMPLETED
Acute Lymphobkastic Leukemia
PETHEMA Foundation
2008-01 PHASE4
NCT02858804 COMPLETED
Mantle Cell Lymphoma
Institute of Hematology & Blood Diseases Hospital, China
2016-01 PHASE4
NCT00058422 COMPLETED
Lymphoma
Memorial Sloan Kettering Cancer Center
2003-02-10 PHASE2
NCT02110069 TERMINATED
Kaposiform Hemangioendothelioma (KHE); Kasabach-Merritt Syndrome; Tufted Angioma
Boston Children's Hospital
2017-06-14 PHASE2
NCT02449278 UNKNOWN
Diffuse Large B-cell Lymphoma
Wuhan University
2015-10 PHASE3
NCT01528046 COMPLETED
Solid Tumors; Primary Brain Tumors
H. Lee Moffitt Cancer Center and Research Institute
2012-09-24 PHASE1
NCT00392327 COMPLETED
Anaplastic Medulloblastoma; Medulloblastoma
Children's Oncology Group
2007-05-23 PHASE3
NCT00945724 COMPLETED
Large B-cell Diffuse Lymphoma of Testis
International Extranodal Lymphoma Study Group (IELSG)
2009-09-27 PHASE2
NCT01889069 COMPLETED
Lymphoma
Hoffmann-La Roche
2013-07-31 PHASE3
NCT02116959 TERMINATED
Advanced Intra-Ocular Retinoblastoma; Retinoblastoma
University of California, San Francisco
2014-07-23 PHASE1
NCT02951728 UNKNOWN
Diffuse Large B Cell Lymphoma
Ruijin Hospital
2016-10 PHASE1; PHASE2
NCT01190930 COMPLETED
Acute Lymphoblastic Leukemia; Adult B Lymphoblastic Lymphoma; Ann Arbor Stage I B Lymphoblastic Lymphoma; Ann Arbor Stage II B Lymphoblastic Lymphoma; Childhood B Acute Lymphoblastic Leukemia; Childhood B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1; Childhood B Lymphoblastic Lymphoma; Down Syndrome; Hypodiploid B Acute Lymphoblastic Leukemia; Philadelphia Chromosome Positive
Children's Oncology Group
2010-08-11 PHASE3
NCT02285062 COMPLETED
Lymphoma, Large B-Cell, Diffuse
Celgene
2015-02-17 PHASE3
NCT03593304 COMPLETED
Vincristine Induced Neurotoxicity; Acute Lymphoblastic Leukaemia
Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
2018-03-29 PHASE2; PHASE3
NCT02541565 COMPLETED
Composite Lymphoma; Grade 3b Follicular Lymphoma; Stage I Diffuse Large B-Cell Lymphoma; Stage I Follicular Lymphoma; Stage II Diffuse Large B-Cell Lymphoma; Stage II Follicular Lymphoma; Stage III Diffuse Large B-Cell Lymphoma; Stage III Follicular Lymphoma; Stage IV Diffuse Large B-Cell Lymphoma; Stage IV Follicular Lymphoma
University of Washington
2015-11-24 PHASE1
NCT02404220 TERMINATED
Acute Lymphoblastic Leukemia
Gilead Sciences
2015-05-06 PHASE1; PHASE2
NCT02212574 TERMINATED
Medulloblastoma
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
2017-04-04 EARLY_PHASE1
NCT00707083 COMPLETED
Leukemia
Prince of Wales Hospital, Shatin, Hong Kong
2008-05-01 PHASE3
NCT02894645 UNKNOWN
Acute Lymphoblastic Leukemia (ALL)
National University Hospital, Singapore
2008-10 PHASE4
NCT00115700 COMPLETED
Follicular Lymphoma
Trans Tasman Radiation Oncology Group
2000-02 PHASE3
NCT00278421 COMPLETED
Lymphoma
German High-Grade Non-Hodgkin's Lymphoma Study Group
2005-11 PHASE3
NCT00866749 COMPLETED
Lymphoblastic Leukemia; Lymphoblastic Lymphoma
M.D. Anderson Cancer Center
2006-09-12 PHASE2
NCT02861040 WITHDRAWN
Recurrent Adult Acute Lymphoblastic Leukemia; Refractory Adult Acute Lymphoblastic Leukemia
Northwestern University
2016-08 PHASE1
NCT00554788 COMPLETED
Extraocular Retinoblastoma
Children's Oncology Group
2008-05-06 PHASE3
NCT03188198 UNKNOWN
Large B Cell Lymphoma
Mansoura University
2016-06-01 PHASE2
NCT02923388 COMPLETED
Vincristine Induced Peripheral Neuropathy (VIPN)
Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
2016-10 PHASE4
NCT01355445 COMPLETED
RHABDOMYOSARCOMA
Centre Oscar Lambret
2012-01 PHASE2
NCT01435018 COMPLETED
HIV-1 Infection
Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
2013-10-01 PHASE3
NCT01622439 COMPLETED
Diffuse Large B-cell Lymphoma
Lund University Hospital
2012-06 PHASE1; PHASE2
NCT00278408 COMPLETED
Lymphoma
German High-Grade Non-Hodgkin's Lymphoma Study Group
2006-01-02 PHASE3
NCT01506453 COMPLETED
Acute Lymphoblastic Leukemia; Neuropathy; Neuropathic Pain
St. Jude Children's Research Hospital
2012-01-24 PHASE2
NCT00500890 TERMINATED
Choroid Plexus Tumors
M.D. Anderson Cancer Center
2005-09-02 PHASE3
NCT02293109 COMPLETED
Contiguous Stage II Adult Lymphoblastic Lymphoma; Noncontiguous Stage II Adult Lymphoblastic Lymphoma; Stage I Adult Lymphoblastic Lymphoma; Stage III Adult Lymphoblastic Lymphoma; Stage IV Adult Lymphoblastic Lymphoma; Untreated Adult Acute Lymphoblastic Leukemia
Mehrdad Abedi, MD
2015-12-17 PHASE1
NCT01156883 COMPLETED
Leukemia
Gruppo Italiano Malattie EMatologiche dell'Adulto
2010-04
NCT00408005 COMPLETED
T Acute Lymphoblastic Leukemia; T Lymphoblastic Lymphoma
National Cancer Institute (NCI)
2007-01-30 PHASE3
NCT00801281 COMPLETED
Follicular Lymphoma; Marginal Zone Lymphoma; Small Lymphocytic Lymphoma; Lymphoplasmacytic Lymphoma
Polish Lymphoma Research Group
2007-02 PHASE3
NCT02419469 TERMINATED
Leukemia; Precursor-B Acute Lymphoblastic Leukemia; Lymphoblastic Lymphoma; Lymphoma
M.D. Anderson Cancer Center
2015-11-13 PHASE2
NCT02594267 COMPLETED
Peripheral T-Cell Lymphoma (PTCL)
Acrotech Biopharma Inc.
2015-11-10 PHASE1
NCT01516567 COMPLETED
Primary Mediastinal Large B Cell Lymphoma
Gustave Roussy, Cancer Campus, Grand Paris
2012-04-01 PHASE2
NCT02072785 UNKNOWN
Adult Acute Lymphoblastic Leukemia
Nanjing Luye Sike Pharmaceutical Co., Ltd.
2013-06 PHASE3
NCT01523977 COMPLETED
Acute Lymphoblastic Leukemia
Dana-Farber Cancer Institute
2011-11 PHASE1
NCT00336024 COMPLETED
Anaplastic Medulloblastoma; Medulloblastoma; Supratentorial Embryonal Tumor, Not Otherwise Specified; Untreated Childhood Supratentorial Primitive Neuroectodermal Tumor
Children's Oncology Group
2007-10-22 PHASE3
NCT01336933 COMPLETED
Anaplastic Large Cell Lymphoma; Angioimmunoblastic T-cell Lymphoma; Hepatosplenic T-cell Lymphoma; Peripheral T-cell Lymphoma
University of Nebraska
2011-07-06 PHASE2
NCT00085202 COMPLETED
Brain and Central Nervous System Tumors
St. Jude Children's Research Hospital
2003-08 PHASE3
NCT02595242 WITHDRAWN
Diffuse Large B Cell Lymphoma
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.
2015-06 PHASE1
NCT00526318 UNKNOWN
Neuroblastoma
German Society for Pediatric Oncology and Hematology GPOH gGmbH
2007-01
NCT01193842 COMPLETED
AIDS-Related Plasmablastic Lymphoma; AIDS-Related Primary Effusion Lymphoma; Ann Arbor Stage I Diffuse Large B-Cell Lymphoma; Ann Arbor Stage I Grade 3 Follicular Lymphoma; Ann Arbor Stage II Diffuse Large B-Cell Lymphoma; Ann Arbor Stage II Grade 3 Contiguous Follicular Lymphoma; Ann Arbor Stage II Grade 3 Non-Contiguous Follicular Lymphoma; Ann Arbor Stage III Diffuse Large B-Cell Lymphoma; Ann Arbor Stage III Grade 3 Follicular Lymphoma; Ann Arbor Stage IV Diffuse Large B-Cell Lymphoma; Ann Arbor Stage IV Grade 3 Follicular Lymphoma; HIV Infection; Plasmablastic Lymphoma; Primary Effusion Lymphoma; Recurrent Diffuse Large B-Cell Lymphoma; Recurrent Grade 3 Follicular Lymphoma
National Cancer Institute (NCI)
2010-10-06 PHASE1; PHASE2
NCT01219816 COMPLETED
B ALL; CD22+ Expression; Refractory B-ALL
Nantes University Hospital
2010-11 PHASE2
NCT00653068 COMPLETED
Childhood Atypical Teratoid/Rhabdoid Tumor
Children's Oncology Group
2009-02-10 PHASE3
NCT00558519 COMPLETED
Leukemia
Alliance for Clinical Trials in Oncology
2008-03-12 PHASE2
NCT01535183 UNKNOWN
Brain Tumor
Seoul National University Hospital
2012-01 PHASE2
NCT01279902 UNKNOWN
Diffuse Large B-cell Lymphoma
Asan Medical Center
2010-08 PHASE2
NCT02531308 TERMINATED
Diffuse Large B-Cell Lymphoma
Rush University Medical Center
2015-07 PHASE2
NCT00379340 COMPLETED
Stage III Kidney Wilms Tumor; Stage IV Kidney Wilms Tumor
Children's Oncology Group
2007-04-30 PHASE3
NCT01055314 COMPLETED
Adult Rhabdomyosarcoma; Childhood Alveolar Rhabdomyosarcoma; Childhood Embryonal Rhabdomyosarcoma; Metastatic Childhood Soft Tissue Sarcoma; Stage IV Adult Soft Tissue Sarcoma; Untreated Childhood Rhabdomyosarcoma
National Cancer Institute (NCI)
2010-01 PHASE2
NCT00450385 TERMINATED
Lymphoma
University of Miami
2007-04-24 PHASE2
NCT00110110 UNKNOWN
Retinoblastoma
The Hospital for Sick Children
2004-06 PHASE2
NCT02337478 TERMINATED
Recurrent Adult Acute Myeloid Leukemia
Wake Forest University Health Sciences
2015-06-05 PHASE2
NCT00920153 TERMINATED
Lymphoma
French Innovative Leukemia Organisation
2008-05 PHASE3
NCT00381680 COMPLETED
B-cell Childhood Acute Lymphoblastic Leukemia; L1 Childhood Acute Lymphoblastic Leukemia; L2 Childhood Acute Lymphoblastic Leukemia; Intermediate Risk Recurrent Childhood Acute Lymphoblastic Leukemia
Children's Oncology Group
2007-03 PHASE3
NCT01332968 COMPLETED
Non-Hodgkin's Lymphoma
Hoffmann-La Roche
2011-07-06 PHASE3
NCT01412879 COMPLETED
Lymphoma
SWOG Cancer Research Network
2011-11 PHASE2
NCT00678327 COMPLETED
Lymphoma
University College, London
2008-08-29 PHASE3
NCT02162771 COMPLETED
Lymphoma, Follicular
Celltrion
2014-07-14 PHASE3
NCT01839097 COMPLETED
Peripheral T-cell Lymphoma
Acrotech Biopharma Inc.
2013-05 PHASE1
NCT00972478 ACTIVE_NOT_RECRUITING
Ann Arbor Stage II Non-Hodgkin Lymphoma; Ann Arbor Stage III Non-Hodgkin Lymphoma; Ann Arbor Stage IV Non-Hodgkin Lymphoma
National Cancer Institute (NCI)
2010-11-15 PHASE1; PHASE2
NCT01439347 TERMINATED
Acute Lymphoblastic Leukemia (ALL)
Spectrum Pharmaceuticals, Inc
2012-03 PHASE3
NCT00634179 COMPLETED
Lymphoma, B-Cell; Follicular Lymphoma
Emory University
2008-02 PHASE1; PHASE2
NCT00669877 COMPLETED
Burkitt's Lymphoma; Burkitt'S-like Lymphoma
M.D. Anderson Cancer Center
2002-08 PHASE2
NCT01946529 COMPLETED
Desmoplastic Small Round Cell Tumor; Ewing Sarcoma of Bone or Soft Tissue; Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor; Metastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor
St. Jude Children's Research Hospital
2013-12-27 PHASE2
NCT00931918 COMPLETED
Non-Germinal B-Cell-like (GCB) Diffuse Large B-cell Lymphoma (DLBCL)
Millennium Pharmaceuticals, Inc.
2009-10 PHASE2
NCT01483690 TERMINATED
Acute Lymphoblastic Leukemia; Precursor B-Cell Lymphoblastic Leukemia; Precursor T-Cell Lymphoblastic Leukemia
Therapeutic Advances in Childhood Leukemia Consortium
2011-12 PHASE1; PHASE2
NCT00450801 COMPLETED
Lymphoma
University of Miami
2004-04 PHASE2
NCT00107198 COMPLETED
Ann Arbor Stage I Childhood Hodgkin Lymphoma; Ann Arbor Stage II Childhood Hodgkin Lymphoma; Childhood Nodular Lymphocyte Predominant B-Cell Lymphoma
Children's Oncology Group
2006-03-10 PHASE2
NCT02228512 WITHDRAWN
Large Cell Lymphoma Arising in KSHV-associated Multicentric Castleman Disease; Primary Effusion Lymphoma
National Cancer Institute (NCI)
2014-08-15 PHASE1; PHASE2
NCT00352027 COMPLETED
Hodgkin's Lymphoma
St. Jude Children's Research Hospital
2006-07-20 PHASE2
NCT00526175 COMPLETED
Acute Lymphoblastic Leukemia
PETHEMA Foundation
2001-06 PHASE4
NCT01403415 COMPLETED
Childhood B Acute Lymphoblastic Leukemia; Childhood T Acute Lymphoblastic Leukemia; Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma; Recurrent Childhood Acute Lymphoblastic Leukemia; Recurrent Childhood Lymphoblastic Lymphoma
National Cancer Institute (NCI)
2011-09 PHASE1
NCT00567567 COMPLETED
Localized Resectable Neuroblastoma; Localized Unresectable Neuroblastoma; Recurrent Neuroblastoma; Regional Neuroblastoma; Stage 4 Neuroblastoma; Stage 4S Neuroblastoma
Children's Oncology Group
2007-11-05 PHASE3
NCT01397825 COMPLETED
Diffuse Large B-Cell Lymphoma; Transformed Follicular Lymphoma; Mantle Cell Lymphoma; Burkitt's Lymphoma
Millennium Pharmaceuticals, Inc.
2011-08-09 PHASE1; PHASE2
NCT00352534 COMPLETED
Stage I Kidney Wilms Tumor; Stage II Kidney Wilms Tumor; Stage III Kidney Wilms Tumor
Children's Oncology Group
2006-11-06 PHASE3
NCT01255514 COMPLETED
Multiple Myeloma
Yonsei University
2008-10-30 PHASE2
NCT00354835 COMPLETED
Adult Rhabdomyosarcoma; Childhood Alveolar Rhabdomyosarcoma; Childhood Botryoid-Type Embryonal Rhabdomyosarcoma; Childhood Embryonal Rhabdomyosarcoma; Localized Childhood Soft Tissue Sarcoma; Rhabdomyosarcoma; Sarcoma; Stage I Adult Soft Tissue Sarcoma AJCC v7; Stage II Adult Soft Tissue Sarcoma AJCC v7; Stage III Adult Soft Tissue Sarcoma AJCC v7
Children's Oncology Group
2006-12-26 PHASE3
NCT01222780 COMPLETED
Sarcoma; Neuroblastoma; Wilms Tumor; Leukemia; Lymphoma; Brain Tumors
Acrotech Biopharma Inc.
2010-09 PHASE1
NCT00506142 COMPLETED
Metastatic Malignant Uveal Melanoma
Spectrum Pharmaceuticals, Inc
2007-11 PHASE2
NCT00526409 COMPLETED
Acute Lymphoblastic Leukemia
PETHEMA Foundation
2005-06 PHASE4
NCT01746173 TERMINATED
T-cell Non-Hodgkin Lymphoma
Dana-Farber Cancer Institute
2013-07 PHASE2
NCT00051311 COMPLETED
Hematologic Neoplasms
National Cancer Institute (NCI)
2003-01-03 PHASE2
NCT01569750 COMPLETED
CD20-positive B-cell Non-Hodgkin Lymphoma
Janssen Research & Development, LLC
2012-06-14 PHASE1
NCT00101010 COMPLETED
Lymphoma
M.D. Anderson Cancer Center
2005-09 PHASE2
NCT00400946 COMPLETED
Drug/Agent Toxicity by Tissue/Organ; Leukemia
Dana-Farber Cancer Institute
2005-04 PHASE3
NCT01313884 TERMINATED
Bone Cancer; Ewing's Sarcoma
Stanford University
2011-05 PHASE2
NCT00038610 COMPLETED
Leukemia
M.D. Anderson Cancer Center
2001-03 PHASE2
NCT00866307 COMPLETED
Acute Lymphoblastic Leukemia; Adult B Acute Lymphoblastic Leukemia; Childhood B Acute Lymphoblastic Leukemia
Children's Oncology Group
2009-02-23 PHASE1
NCT00632827 TERMINATED
Peripheral T-Cell Lymphoma
University of California, San Francisco
2008-07-01 PHASE2
NCT01000285 COMPLETED
Leukemia-Lymphoma, Adult T-Cell
Washington University School of Medicine
2010-09 PHASE1; PHASE2
NCT00458848 COMPLETED
Leukemia
Gruppo Italiano Malattie EMatologiche dell'Adulto
2004-10 PHASE2
NCT01415765 WITHDRAWN
Lymphoma, Diffuse Large-Cell B-cell; Diffuse, Large B-cell Lymphoma; Lymphoma, Diffuse Large-Cell; Large-Cell Lymphoma, Diffuse
National Cancer Institute (NCI)
2011-07-15 PHASE1; PHASE2
NCT01414855 COMPLETED
Lymphoma, B-Cell
Genentech, Inc.
2011-08-31 PHASE2
NCT00103285 COMPLETED
Acute Lymphoblastic Leukemia; Childhood B Acute Lymphoblastic Leukemia
Children's Oncology Group
2005-04-11 PHASE3
NCT00290667 COMPLETED
Lymphoma
German High-Grade Non-Hodgkin's Lymphoma Study Group
2004-02 PHASE2
NCT00107380 COMPLETED
Lymphoma
SWOG Cancer Research Network
2005-11 PHASE2
NCT01014767 TERMINATED
Brain Cancer; Choroid Plexus Tumors
Tufts Medical Center
2009-11 PHASE3
NCT01004991 COMPLETED
Diffuse Large B Cell Lymphoma
Weill Medical College of Cornell University
2010-01 PHASE1; PHASE2
NCT00671658 COMPLETED
Leukemia; Acute Lymphoblastic Leukemia
M.D. Anderson Cancer Center
2002-11 PHASE2
NCT00541411 UNKNOWN
Ewing's Sarcoma
King Faisal Specialist Hospital & Research Center
2003-06
NCT01005914 TERMINATED
Leukemia
OHSU Knight Cancer Institute
2009-06 PHASE2
NCT00072384 COMPLETED
Intraocular Retinoblastoma
Children's Oncology Group
2007-04-16 PHASE3
NCT00993044 COMPLETED
Refractory Solid Tumors in Children
Children's Hospital Los Angeles
2009-09 PHASE1
NCT00882206 TERMINATED
Leukemia; Lymphoma
Masonic Cancer Center, University of Minnesota
2009-04 PHASE2
NCT00911183 COMPLETED
Lymphoma
Institut Bergonié
2008-12-02 PHASE2
NCT00184002 COMPLETED
Non-Hodgkin's Lymphoma
University of Southern California
2003-01-10 PHASE2
NCT00555464 TERMINATED
Hemangioma
Medical College of Wisconsin
2007-11 PHASE2
NCT00376961 COMPLETED
Lymphoma
SWOG Cancer Research Network
2006-08 PHASE2
NCT00581776 COMPLETED
Mantle Cell Lymphoma
University of Wisconsin, Madison
2005-05 PHASE2
NCT00853008 COMPLETED
Acute Lymphoblastic Leukemia
PETHEMA Foundation
2003-01 PHASE4
NCT00262925 TERMINATED
Recurrent Adult Acute Lymphoblastic Leukemia
National Cancer Institute (NCI)
2006-06 PHASE2
NCT00544219 COMPLETED
Lymphoma
Swiss Cancer Institute
2007-09
NCT00666484 COMPLETED
Lymphoma; Neurotoxicity
University College, London
2008-03 PHASE2
NCT01040871 COMPLETED
Diffuse Large B-Cell Lymphoma
Millennium Pharmaceuticals, Inc.
2010-01 PHASE2
NCT00268853 COMPLETED
Diffuse Large-Cell Lymphoma
CTI BioPharma
2005-11 PHASE2
NCT00877006 COMPLETED
Non-Hodgkin's Lymphoma; Mantle Cell Lymphoma
Teva Branded Pharmaceutical Products R&D, Inc.
2009-04-30 PHASE3
NCT01181999 UNKNOWN
Lymphoma, Large B-cell, Diffuse
Chonnam National University Hospital
2010-08 PHASE2
NCT01468740 UNKNOWN
HIV-associated Hodgkin Lymphoma
Harlachinger Krebshilfe e.V.
2004-03 PHASE2
NCT00430118 COMPLETED
Leukemia
University Hospital Schleswig-Holstein
2000-07 PHASE3
NCT00901069 COMPLETED
Lymphoma; Hodgkin Disease; Lymphoma, Non-Hodgkin
Shams Shakil
2009-05 PHASE1
NCT00020566 UNKNOWN
Sarcoma
University of Leicester
2001-02 PHASE3
NCT00184041 COMPLETED
Acute Lymphoblastic Leukemia
University of Southern California
2004-07 PHASE2
NCT00002766 COMPLETED
Leukemia; Lymphoma
Memorial Sloan Kettering Cancer Center
1996-03 PHASE3
NCT00006721 COMPLETED
Lymphoma
SWOG Cancer Research Network
2001-03 PHASE3
NCT00133991 COMPLETED
Leukemia; Lymphoma
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
2005-07 PHASE2
NCT01009970 UNKNOWN
Diffuse Large B-Cell Lymphoma
Fondazione Italiana Linfomi - ETS
2010-05 PHASE2
NCT00379457 UNKNOWN
Sarcoma
European Paediatric Soft Tissue Sarcoma Study Group
2006-06 PHASE3
NCT00031590 TERMINATED
Brain Tumors; Central Nervous System Tumors; Medulloblastoma
Children's Hospital of Philadelphia
2001-04 PHASE2
NCT00983944 WITHDRAWN
Lymphoma
Ohio State University Comprehensive Cancer Center
2009-09 PHASE2
NCT00245089 UNKNOWN
Sarcoma
Japan Rhabdomyosarcoma Study Group
2004-05 PHASE2
NCT00245141 UNKNOWN
Sarcoma
Japan Rhabdomyosarcoma Study Group
2004-05 PHASE2
NCT00991133 COMPLETED
Lymphoblastic Leukemia, Acute, Childhood
Genzyme, a Sanofi Company
2009-10 PHASE1
NCT00562965 TERMINATED
Lymphoma, Follicular
Pfizer
2007-11 PHASE3
NCT01184885 COMPLETED
Lymphoid Malignancies (New or Relapsed); Acute Lymphoblastic Leukemia; Burkitt Lymphoma; Lymphoblastic Lymphoma; Mantle Cell Lymphoma; Adult T-cell Leukemia/Lymphoma
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
2010-07 EARLY_PHASE1
NCT00131027 UNKNOWN
Lymphoblastic Leukemia, Acute
Japan Adult Leukemia Study Group
2002-09 PHASE3
NCT00088881 TERMINATED
Contiguous Stage II Adult Diffuse Large Cell Lymphoma; Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue; Nodal Marginal Zone B-cell Lymphoma; Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma; Splenic Marginal Zone Lymphoma; Stage I Adult Diffuse Large Cell Lymphoma; Testicular Lymphoma; Waldenström Macroglobulinemia
National Cancer Institute (NCI)
2004-12 PHASE2
NCT00440726 COMPLETED
Acute Lymphoblastic Leukemia
Therapeutic Advances in Childhood Leukemia Consortium
2006-08-04 PHASE1; PHASE2
NCT00960063 TERMINATED
Neoplasms; Solid Tumors; Bone Cancer; Kidney Tumor; Neuroblastoma
Merck Sharp & Dohme LLC
2009-11-11 PHASE1
NCT00392886 UNKNOWN
Brain and Central Nervous System Tumors
Children's Hospital Los Angeles
2004-03 PHASE3
NCT01066429 UNKNOWN
Diffuse Large B-Cell Lymphoma (DLBCL)
Hospital Universitario Principe de Asturias
2009-12 PHASE2
NCT01527422 COMPLETED
Lymphoma; Non Hodgkin's Lymphoma
Fernando Cabanillas
2006-01 PHASE1; PHASE2
NCT01458730 COMPLETED
Central Nervous System Lymphoma
University of Aarhus
2007-05 PHASE2
NCT00801580 UNKNOWN
Lymphoid Leukemia
University of Bologna
2008-03 PHASE2
NCT00495079 COMPLETED
Acute Lymphoblastic Leukemia (ALL)
Spectrum Pharmaceuticals, Inc
2007-05 PHASE2
NCT00503594 UNKNOWN
Lymphoma
Assistance Publique - Hôpitaux de Paris
2007-07 PHASE2
NCT00928200 TERMINATED
Relapsed Acute Lymphoblastic Leukemia; Allergy to PEG e.Coli Asparaginase; Allergy to Native e.Coli Asparaginase
Therapeutic Advances in Childhood Leukemia Consortium
2009-04-13 PHASE1
NCT00135499 TERMINATED
Lymphoma, Large-Cell, Diffuse
Lymphoma Study Association
2001-10-16 PHASE3
NCT00077207 COMPLETED
Brain Tumor; Central Nervous System Tumor
Children's Oncology Group
2004-07
NCT00274911 UNKNOWN
Brain and Central Nervous System Tumors
Children's Cancer and Leukaemia Group
2004-02 PHASE2
NCT00186979 COMPLETED
Solid Tumors
St. Jude Children's Research Hospital
2003-05 PHASE1
NCT00278278 UNKNOWN
Brain and Central Nervous System Tumors
German Society for Pediatric Oncology and Hematology GPOH gGmbH
2003-09 PHASE3
NCT00392340 UNKNOWN
Neuroblastoma
Children's Cancer and Leukaemia Group
2008-03 PHASE2
NCT00126191 TERMINATED
Burkitt Lymphoma; Non-Hodgkins Lymphoma; Atypical Burkitt Lymphoma
Dana-Farber Cancer Institute
2005-07 PHASE2
NCT00071058 COMPLETED
Adrenal Cortex Neoplasms
National Cancer Institute (NCI)
2003-10 PHASE2
NCT00057811 COMPLETED
Childhood Burkitt Lymphoma; Childhood Diffuse Large Cell Lymphoma; Childhood Immunoblastic Large Cell Lymphoma; Stage I Childhood Large Cell Lymphoma; Stage I Childhood Small Noncleaved Cell Lymphoma; Stage II Childhood Large Cell Lymphoma; Stage II Childhood Small Noncleaved Cell Lymphoma; Stage III Childhood Large Cell Lymphoma; Stage III Childhood Small Noncleaved Cell Lymphoma; Stage IV Childhood Large Cell Lymphoma; Stage IV Childhood Small Noncleaved Cell Lymphoma; Untreated Childhood Acute Lymphoblastic Leukemia
Children's Oncology Group
2004-06 PHASE2
NCT00562068 UNKNOWN
Lymphoma; Small Intestine Cancer
Cancer Research UK
2007-05 PHASE1
NCT00494780 COMPLETED
Lymphoma, Follicular
GlaxoSmithKline
2007-06 PHASE2
NCT00313079 COMPLETED
Leukemia, Lymphocytic; Leukemia; Acute Lymphocytic Leukemia
Steven E. Coutre
2006-05 PHASE1
NCT00718757 COMPLETED
Non-Hodgkins Lymphoma; Hodgkin's Disease; Acute Lymphoblastic Leukemia
St. Jude Children's Research Hospital
2005-01 PHASE1
NCT00618501 COMPLETED
Leukemia
Asan Medical Center
2005-10 PHASE2
NCT00025103 UNKNOWN
Kidney Cancer
Children's Cancer and Leukaemia Group
2001-05 PHASE2
NCT00136435 COMPLETED
Acute Lymphoblastic Leukemia
Dana-Farber Cancer Institute
2002-06 PHASE2
NCT00384111 TERMINATED
Follicular Lymphoma; Lymphoma, Follicular
Spectrum Pharmaceuticals, Inc
2006-10 PHASE3
NCT00301821 COMPLETED
Lymphoma
Alliance for Clinical Trials in Oncology
2006-01 PHASE2
NCT00176462 COMPLETED
Acute Lymphocytic Leukemia
Rutgers, The State University of New Jersey
2001-02 PHASE2
NCT00136084 COMPLETED
Leukemia, Myelocytic, Acute
St. Jude Children's Research Hospital
2002-08 PHASE3
NCT00003728 UNKNOWN
Leukemia; Lymphoma
European Organisation for Research and Treatment of Cancer - EORTC
1998-12 PHASE3
NCT00313053 TERMINATED
Leukemia, Lymphocytic, Acute; Leukemia; Acute Lymphoid Leukemia (ALL)
Clare Twist
2004-09 PHASE1
NCT00072280 TERMINATED
Sarcoma
Children's Oncology Group
2004-11 PHASE2
NCT00774202 COMPLETED
Immune Thrombocytopenic Purpura
Weill Medical College of Cornell University
2003-11 PHASE2; PHASE3
NCT00061945 COMPLETED
Acute Undifferentiated Leukemia; B-cell Adult Acute Lymphoblastic Leukemia; B-cell Childhood Acute Lymphoblastic Leukemia; L1 Adult Acute Lymphoblastic Leukemia; L1 Childhood Acute Lymphoblastic Leukemia; L2 Adult Acute Lymphoblastic Leukemia; L2 Childhood Acute Lymphoblastic Leukemia; Philadelphia Chromosome Negative Adult Precursor Acute Lymphoblastic Leukemia; Philadelphia Chromosome Positive Adult Precursor Acute Lymphoblastic Leukemia; Philadelphia Chromosome Positive Childhood Precursor Acute Lymphoblastic Leukemia; T-cell Adult Acute Lymphoblastic Leukemia; T-cell Childhood Acute Lymphoblastic Leukemia; Untreated Adult Acute Lymphoblastic Leukemia; Untreated Childhood Acute Lymphoblastic Leukemia
National Cancer Institute (NCI)
2003-06 PHASE1; PHASE2
NCT00003141 COMPLETED
Brain Tumors; Central Nervous System Tumors; Neuroblastoma; Sarcoma
Children's Oncology Group
1998-03 PHASE1
NCT00337987 COMPLETED
Peripheral T-Cell Lymphoma
Yale University
2005-11 PHASE2
NCT00058305 COMPLETED
Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue; Nodal Marginal Zone B-cell Lymphoma; Recurrent Adult Diffuse Large Cell Lymphoma; Recurrent Adult Diffuse Mixed Cell Lymphoma; Recurrent Adult Diffuse Small Cleaved Cell Lymphoma; Recurrent Grade 1 Follicular Lymphoma; Recurrent Grade 2 Follicular Lymphoma; Recurrent Grade 3 Follicular Lymphoma; Recurrent Mantle Cell Lymphoma; Recurrent Marginal Zone Lymphoma; Recurrent Small Lymphocytic Lymphoma; Splenic Marginal Zone Lymphoma
National Cancer Institute (NCI)
2003-03 PHASE2
NCT00005945 COMPLETED
Leukemia
Children's Oncology Group
2000-06 PHASE3
NCT00041132 COMPLETED
Lymphoma
SWOG Cancer Research Network
2002-09 PHASE2
NCT00763763 COMPLETED
Leukemia, Lymphocytic, Acute; Philadelphia Chromosome; Blast Crisis; Leukemia, Myeloid, Chronic
Assistance Publique - Hôpitaux de Paris
2004-12 PHASE2
NCT00025363 COMPLETED
Alveolar Childhood Rhabdomyosarcoma; Embryonal Childhood Rhabdomyosarcoma; Embryonal-botryoid Childhood Rhabdomyosarcoma; Previously Treated Childhood Rhabdomyosarcoma; Recurrent Childhood Rhabdomyosarcoma
National Cancer Institute (NCI)
2001-11 PHASE2
NCT00003573 COMPLETED
Brain Tumors; Central Nervous System Tumors
Children's Oncology Group
1998-11 PHASE2
NCT00004188 COMPLETED
Neuroblastoma
Children's Oncology Group
2001-02 PHASE3
NCT00003203 COMPLETED
Brain Tumors; Central Nervous System Tumors; Neuroblastoma
Children's Oncology Group
1998-03 PHASE2
NCT00145041 COMPLETED
Malignant Melanoma
Acrotech Biopharma Inc.
2005-02 PHASE1
NCT00005585 COMPLETED
Leukemia
Children's Oncology Group
2000-04 PHASE3
NCT00003311 COMPLETED
Lymphoma
M.D. Anderson Cancer Center
1998-05-20 PHASE2
NCT00002565 COMPLETED
Lymphoma
M.D. Anderson Cancer Center
1994-05-25 PHASE3
NCT00002463 COMPLETED
Brain and Central Nervous System Tumors
M.D. Anderson Cancer Center
1989-02 PHASE2
NCT00053768 COMPLETED
Lymphoma
German High-Grade Non-Hodgkin's Lymphoma Study Group
2002-04 PHASE3
NCT00020943 COMPLETED
Lymphoma
Alliance for Clinical Trials in Oncology
2001-06 PHASE2
NCT00041327 COMPLETED
Lymphoma
AIDS Malignancy Consortium
2002-10 PHASE2
NCT00002676 COMPLETED
Lymphoma
Alliance for Clinical Trials in Oncology
1995-07 PHASE2
NCT00006734 COMPLETED
Sarcoma
Children's Oncology Group
2001-05 PHASE3
NCT00004231 COMPLETED
Lymphoma
Northwestern University
1999-10 PHASE2
NCT00144963 COMPLETED
Acute Lymphoblastic Leukemia
Acrotech Biopharma Inc.
2002-07 PHASE1; PHASE2
NCT00054158 COMPLETED
Multiple Myeloma and Plasma Cell Neoplasm
Roswell Park Cancer Institute
2004-08 PHASE2
NCT00309881 COMPLETED
Chronic Lymphocytic Leukemia
German CLL Study Group
2003-04 PHASE2
NCT01225874 COMPLETED
Leukemia
Children's Oncology Group
1999-12
NCT00049569 COMPLETED
L1 Childhood Acute Lymphoblastic Leukemia; L2 Childhood Acute Lymphoblastic Leukemia; Non-T, Non-B Childhood Acute Lymphoblastic Leukemia; Recurrent Childhood Acute Lymphoblastic Leukemia; T-cell Childhood Acute Lymphoblastic Leukemia
National Cancer Institute (NCI)
2003-01
NCT00005964 COMPLETED
Lymphoma
Alliance for Clinical Trials in Oncology
2000-05 PHASE2
NCT01148446 COMPLETED
Elderly Patients (>65 Years); Diffuse Large B Cell Lymphoma (DLBCL)
Fondazione Italiana Linfomi - ETS
2003-01 PHASE3
NCT00285389 COMPLETED
Mantle Cell Lymphoma
French Innovative Leukemia Organisation
2002-02 PHASE2
NCT00284271 COMPLETED
Hodgkin´s Lymphoma
University of Cologne
2004-01 PHASE2
NCT00017368 COMPLETED
Neuroblastoma
Children's Oncology Group
2001-04 PHASE2
NCT00005596 COMPLETED
Leukemia
Children's Oncology Group
2000-04 PHASE3
NCT00002466 COMPLETED
Kidney Cancer; Sarcoma
Memorial Sloan Kettering Cancer Center
1990-05 PHASE2
NCT00002569 COMPLETED
Brain and Central Nervous System Tumors
Radiation Therapy Oncology Group
1994-07 PHASE3
NCT00039351 COMPLETED
Lymphoma
European Organisation for Research and Treatment of Cancer - EORTC
2002-03 PHASE2
NCT00003955 COMPLETED
Sarcoma
Children's Oncology Group
1999-09 PHASE2
NCT00006095 COMPLETED
Unspecified Childhood Solid Tumor, Protocol Specific
Children's Oncology Group
2000-07 PHASE1
NCT00032019 COMPLETED
Lymphoma
Alliance for Clinical Trials in Oncology
2002-02 PHASE2
NCT00002827 COMPLETED
Cardiac Toxicity; Lymphoma
Children's Oncology Group
1996-10 PHASE3
NCT00038207 COMPLETED
Soft Tissue Sarcoma; Lymphoma; Leukemia; Wilms' Tumor; Osteosarcoma
M.D. Anderson Cancer Center
2000-06 PHASE2
NCT00002704 COMPLETED
Leukemia
National Cancer Institute (NCI)
1996-01 PHASE2
NCT00187122 COMPLETED
Lymphoblastic Lymphoma
St. Jude Children's Research Hospital
1993-03
NCT00004179 COMPLETED
Lymphoma
European Organisation for Research and Treatment of Cancer - EORTC
1999-05 PHASE3
NCT00002494 COMPLETED
Leukemia; Lymphoma
Alliance for Clinical Trials in Oncology
1992-05 PHASE2
NCT00003309 COMPLETED
Brain and Central Nervous System Tumors
Eastern Cooperative Oncology Group
1999-05-04 PHASE2
NCT00002700 COMPLETED
Leukemia; Lymphoma
European Organisation for Research and Treatment of Cancer - EORTC
1995-08 PHASE3
NCT00003700 COMPLETED
Leukemia
Alliance for Clinical Trials in Oncology
1999-01 PHASE2
NCT00199056 COMPLETED
Adult Acute Lymphocytic Leukemia
Goethe University
1999-10 PHASE4
NCT00002657 COMPLETED
Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm
SWOG Cancer Research Network
1995-05 PHASE2
NCT00004010 COMPLETED
Lymphoma
Children's Oncology Group
1999-10 PHASE2
NCT00002757 COMPLETED
Leukemia; Lymphoma
Children's Oncology Group
2001-06 PHASE3
NCT00002548 COMPLETED
Multiple Myeloma
SWOG Cancer Research Network
1994-01 PHASE3
NCT00022555 COMPLETED
AIDS-related Diffuse Large Cell Lymphoma; AIDS-related Diffuse Mixed Cell Lymphoma; AIDS-related Peripheral/Systemic Lymphoma; AIDS-related Small Noncleaved Cell Lymphoma
National Cancer Institute (NCI)
2001-11 PHASE1
NCT00199095 COMPLETED
Adult Acute Lymphocytic Leukemia
Goethe University
1997-02 PHASE4
NCT00002878 COMPLETED
Multiple Myeloma and Plasma Cell Neoplasm
Eastern Cooperative Oncology Group
1997-06-30 PHASE3
NCT00072007 COMPLETED
Leukemia
Swiss Cancer Institute
2002-06 PHASE2
NCT00002806 COMPLETED
Brain and Central Nervous System Tumors
Alliance for Clinical Trials in Oncology
1996-07 PHASE2
NCT00002471 COMPLETED
Leukemia; Lymphoma
Memorial Sloan Kettering Cancer Center
1990-02 PHASE2
NCT00003671 COMPLETED
Leukemia
Children's Oncology Group
1998-12 PHASE2
NCT00002816 COMPLETED
Leukemia
Children's Oncology Group
1996-12 PHASE3
NCT00187005 TERMINATED
Acute Lymphoblastic Leukemia
St. Jude Children's Research Hospital
1998-07 PHASE3
NCT00002610 COMPLETED
Kidney Cancer
Children's Oncology Group
1996-01 PHASE3
NCT00002611 COMPLETED
Kidney Cancer
Children's Oncology Group
1995-07 PHASE3
NCT00002840 COMPLETED
Brain and Central Nervous System Tumors
European Organisation for Research and Treatment of Cancer - EORTC
1996-08 PHASE3
NCT00002665 COMPLETED
Leukemia; Neutropenia; Thrombocytopenia
SWOG Cancer Research Network
1995-07 PHASE2
NCT00187070 COMPLETED
Lymphoma, Large Cell; Lymphoma, Non-Hodgkin
St. Jude Children's Research Hospital
1997-12
NCT00003166 COMPLETED
Recurrent Adult Burkitt Lymphoma; Recurrent Adult Diffuse Large Cell Lymphoma; Recurrent Adult Diffuse Mixed Cell Lymphoma; Recurrent Adult Immunoblastic Large Cell Lymphoma; Recurrent Adult Lymphoblastic Lymphoma; Recurrent Grade 3 Follicular Lymphoma; Recurrent Mantle Cell Lymphoma; Refractory Chronic Lymphocytic Leukemia; Refractory Multiple Myeloma; Stage III Multiple Myeloma
National Cancer Institute (NCI)
1998-05 PHASE1
NCT00002794 COMPLETED
Retinoblastoma
St. Jude Children's Research Hospital
1996-02 PHASE2
NCT00003625 COMPLETED
Brain Tumors; Central Nervous System Tumors
Children's Oncology Group
1998-12 PHASE1
NCT00003847 TERMINATED
Lung Cancer
Vertex Pharmaceuticals Incorporated
1998-12 PHASE2
NCT00004162 COMPLETED
Lymphoma
University of Alabama at Birmingham
1997-06 PHASE1
NCT00002618 COMPLETED
Lymphoma
Children's Oncology Group
1994-12 PHASE3
NCT00002691 COMPLETED
Lymphoma
Memorial Sloan Kettering Cancer Center
1995-08 PHASE2
NCT00002462 ACTIVE_NOT_RECRUITING
Lymphoma
European Organisation for Research and Treatment of Cancer - EORTC
1989-09 PHASE3
NCT00006669 WITHDRAWN
Lymphoma
Medstar Health Research Institute
1999-09 PHASE2
NCT00004039 WITHDRAWN
Lymphoma
Hoag Memorial Hospital Presbyterian
1998-06 PHASE2
NCT00199069 COMPLETED
Adult Acute Lymphocytic Leukemia
Goethe University
1993-04 PHASE4
NCT00379041 ACTIVE_NOT_RECRUITING
Lymphoma
European Organisation for Research and Treatment of Cancer - EORTC
1993-09-01 PHASE3
NCT00028886 UNKNOWN
Multiple Myeloma and Plasma Cell Neoplasm
Commissie Voor Klinisch Toegepast Onderzoek
2001-03 PHASE3
NCT00000658 COMPLETED
Lymphoma, Non-Hodgkin; HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE3
NCT00556127 COMPLETED
Diffuse Large B-Cell Lymphoma; POOR PROGNOSIS
Gruppo Italiano Multiregionale per lo studio dei Linfomi e delle Leucemie
2002-06 PHASE2
NCT00001339 COMPLETED
Adrenal Cortical Carcinoma
National Cancer Institute (NCI)
1993-08 PHASE2
NCT00003421 COMPLETED
Lymphoma
Medical Research Council
1998-06 PHASE3
NCT00025649 COMPLETED
Neuroblastoma
European Infant Neuroblastoma Study Group - 1999
1999-07 PHASE2
NCT00000954 COMPLETED
Sarcoma, Kaposi; HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00734773 WITHDRAWN
Brain and Central Nervous System Tumors; Lymphoma; Neurotoxicity
Northwestern University
2008-11 EARLY_PHASE1
NCT00025428 COMPLETED
Neuroblastoma
Societe Internationale d'Oncologie Pediatrique
2000-12 PHASE3
NCT00161564 WITHDRAWN
Idiopathic Thrombocytopenic Purpura (ITP)
Weill Medical College of Cornell University
2004-02 PHASE2
NCT00025441 COMPLETED
Ovarian Cancer; Sarcoma; Small Intestine Cancer
Societe Internationale d'Oncologie Pediatrique
1998-11 PHASE2
NCT00002898 COMPLETED
Childhood Malignant Fibrous Histiocytoma of Bone; Sarcoma
Societe Internationale d'Oncologie Pediatrique
1995-01 PHASE3
NCT00025064 UNKNOWN
Lymphoma
Children's Cancer and Leukaemia Group
2000-01 PHASE2
NCT00003437 UNKNOWN
Leukemia
Medical Research Council
1997-01 PHASE3
NCT00006232 COMPLETED
Multiple Myeloma and Plasma Cell Neoplasm
West of Scotland Lymphoma Group
1996-10 PHASE3
NCT00005959 UNKNOWN
Lymphoma
Amgen
1999-12 PHASE2
NCT00344422 COMPLETED
Multiple Myeloma; Myeloma; M-Protein; Myeloma Proteins
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
2000-10 PHASE3
NCT00002499 UNKNOWN
Leukemia
Grupo Argentino de Tratamiento de la Leucemia Aguda
1990-01 PHASE2; PHASE3
NCT00004224 COMPLETED
Brain and Central Nervous System Tumors
Societe Internationale d'Oncologie Pediatrique
1999-01 PHASE2
NCT00003262 UNKNOWN
Lymphoma
Centro di Riferimento Oncologico - Aviano
1997-05 PHASE2
NCT00002531 UNKNOWN
Leukemia
Johann Wolfgang Goethe University Hospital
1993-01 PHASE2
NCT00491946 UNKNOWN
Cancer
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
2004-06 PHASE4
NCT00004218 COMPLETED
Leukemia
Leukemia Research Fund
1999-10 PHASE3
NCT00070447 COMPLETED
Lymphoma
National Cancer Institute (NCI)
2003-11 PHASE2
NCT00041210 UNKNOWN
Lymphoma
Mount Vernon Cancer Centre at Mount Vernon Hospital
2001-10 PHASE3
NCT00028717 UNKNOWN
Lymphoma
Commissie Voor Klinisch Toegepast Onderzoek
2001-02 PHASE3
NCT00001209 COMPLETED
Neuroectodermal Tumor, Primitive; Neuroepithelioma; Osteosarcoma; Sarcoma; Sarcoma, Ewing's
National Cancer Institute (NCI)
1986-10 PHASE1
NCT00417053 UNKNOWN
Neuroblastoma
Children's Cancer and Leukaemia Group
PHASE3
NCT00003273 WITHDRAWN
Brain and Central Nervous System Tumors; Neuroblastoma; Retinoblastoma; Sarcoma
NYU Langone Health
1997-11 PHASE2
NCT00276731 UNKNOWN
Neuroblastoma
Children's Cancer and Leukaemia Group
1995-03 PHASE3
NCT00022945 COMPLETED
Mantle Cell Lymphoma
Corixa Corporation
PHASE2
NCT00343369 UNKNOWN
Leukemia
Universitätsklinikum Hamburg-Eppendorf
2003-01
NCT00187161 COMPLETED
Non-Hodgkin Lymphoma; Acute Lymphoblastic Leukemia, Mature B-Cell
St. Jude Children's Research Hospital
1994-11 PHASE2
NCT00018954 COMPLETED
Leukemia; Lymphoma
National Institutes of Health Clinical Center (CC)
1992-10 PHASE2
NCT00281905 UNKNOWN
Brain and Central Nervous System Tumors; Neuroblastoma
Children's Cancer and Leukaemia Group
1992-06 PHASE2
NCT00080925 COMPLETED
Chronic Myeloproliferative Disorders; Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Neoplasms
National Institutes of Health Clinical Center (CC)
2004-02 PHASE1
NCT00030719 UNKNOWN
Neuroblastoma
University of Leicester
2001-12 PHASE3
NCT00003493 COMPLETED
Multiple Myeloma and Plasma Cell Neoplasm
The Cleveland Clinic
1998-11 PHASE2
NCT00025623 COMPLETED
Neuroblastoma
European Infant Neuroblastoma Study Group - 1999
1999-07 PHASE2
NCT00012207 COMPLETED
Leukemia; Lymphoma
Fred Hutchinson Cancer Center
2000-09 PHASE1
NCT00669812 UNKNOWN
Lymphoma; Small Intestine Cancer
Cancer Research UK
2008-02 PHASE2
NCT00002987 UNKNOWN
Lymphoma
Medical Research Council
1997-01 PHASE3
NCT00365755 COMPLETED
Neuroblastoma
Children's Cancer and Leukaemia Group
PHASE3
NCT00416377 UNKNOWN
Lymphoma
Children's Cancer and Leukaemia Group
NCT00003578 UNKNOWN
Lymphoma
Lymphoma Trials Office
1993-01 PHASE3
NCT00025610 COMPLETED
Neuroblastoma
European Infant Neuroblastoma Study Group - 1999
1999-07 PHASE2
NCT00053872 UNKNOWN
Brain and Central Nervous System Tumors
University of Leicester
2003-02 PHASE3
NCT00427570 COMPLETED
Colorectal Cancer
NSABP Foundation Inc
1977-09 PHASE3
NCT00201318 COMPLETED
Non-Hodgkin's Lymphoma
National Health Research Institutes, Taiwan
2001-09 PHASE2
NCT00001689 COMPLETED
Acute Lymphocytic Leukemia; Leukemia
National Cancer Institute (NCI)
1998-01 PHASE1

(data from https://clinicaltrials.gov, updated on 2026-06-11)

Check the Vincristine (Leurocristine) Sulfate product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Compliance for Clinical Use

Mechanism and Biochemical Profile

Vincristine sulfate binds irreversibly to tubulin and inhibits microtubule polymerization, thereby disrupting mitotic spindle formation and arresting cells in metaphase. This failure of mitotic progression induces apoptosis in rapidly dividing cells, suppressing tumor growth in clinical trial contexts such as acute lymphoblastic leukemia, non-Hodgkin lymphoma, and pediatric solid tumors.

Appendix RUO and cGMP Quality Standards

Quality Dimension RUO (Research Use Only) cGMP (Current Good Manufacturing Practice)
Clinical Applicability Prohibited in human clinical trials or medical diagnostics. Mandatory for human clinical trials (Phase I–III) and therapies.
Regulatory Status Non-regulated grade; exempt from drug manufacturing laws. Legally enforced by health authorities (e.g., FDA, EMA, NMPA).
Facility Environment Unclassified analytical or research laboratories. Validated Cleanrooms (ISO Class 5–8) with continuous monitoring.
Quality Control Basic purity and activity testing. Rigorous safety release testing (Sterility, Endotoxin, Mycoplasma).
Process Validation Basic equipment calibration; no process validation required. Full qualification (IQ/OQ/PQ) and complete batch records.
Quality Assurance Vendor self-declared without required formal QMS. Mandatory QA/QC unit, Change Control, CAPA, and vendor audits.
Regulatory Impact High risk of IND rejection if used as a critical raw material. Required for IND/NDA filings, supported by Drug Master Files (DMF).

Footnotes

Regulatory Note: Governed by FDA (21 CFR Parts 210/211/312), EMA (EudraLex Vol 4), ICH Guidelines (E6/Q7/Q9/Q10), and compendial standards (USP <71>/<85>/<1043>).

Note: Technical data last updated: Sep 1, 2026.