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U0126-EtOH is an effective ERK1/2 inhibitor. It affects ERK MAPK signaling by blocking ERK1/2 phosphorylation, inhibiting microglial cell responses and modulating macrophage polarization during infection.
U0126-EtOH: Mechanism of Action
U0126-EtOH MOA：Targeting MEK1/2/ERK Pathway for Oncology