Numerous clinical trials evaluate thalidomide across developmental stages ranging from Early Phase 1 through Phase 4. These studies investigate its pharmacodynamics and therapeutic efficacy in conditions including multiple myeloma, solid tumors, transfusion-dependent beta-thalassemia, and autoimmune disorders. Sponsored by academic medical centers, specialized hospitals, and national research institutes, these trials encompass recruitment statuses spanning completed, active, recruiting, withdrawn, and terminated protocols.
| NCT Number | Recruitment | Conditions | Sponsor/Collaborators | Start Date | Phases |
|---|---|---|---|---|---|
| NCT07309419 | NOT_YET_RECRUITING | Hepatocellular Carcinoma |
Shanghai Zhongshan Hospital |
2025-12-22 | PHASE2; PHASE3 |
| NCT01356290 | RECRUITING | Medulloblastoma Recurrent; Ependymoma Recurrent; ATRT Recurrent; Rare CNS Tumor Recurrent |
Medical University of Vienna |
2014-04 | PHASE2 |
| NCT07671534 | RECRUITING | Solid Tumor Cancer |
Sarcoma Oncology Research Center, LLC |
2026-06 | PHASE2 |
| NCT06617182 | RECRUITING | Radiation Enteritis |
Yongquan Shi |
2024-09-30 | PHASE2 |
| NCT07746245 | NOT_YET_RECRUITING | Peripheral T-Cell Lymphoma |
The First Affiliated Hospital with Nanjing Medical University |
2026-08-01 | PHASE2 |
| NCT07195799 | RECRUITING | Non-Hodgkin Lymphoma |
The First Affiliated Hospital with Nanjing Medical University |
2024-12-31 | PHASE2 |
| NCT07338344 | RECRUITING | Transfusion-dependent β-thalassemia Patients |
Rongrong Liu |
2026-02-01 | PHASE2 |
| NCT00871013 | ACTIVE_NOT_RECRUITING | Myeloma |
University of Arkansas |
2009-03 | PHASE2 |
| NCT00869232 | ACTIVE_NOT_RECRUITING | Multiple Myeloma |
University of Arkansas |
2008-10 | PHASE2 |
| NCT07204041 | ACTIVE_NOT_RECRUITING | Langerhans Cell Histiocytosis (LCH) |
Cancer Institute and Hospital, Chinese Academy of Medical Sciences |
2025-08-01 | PHASE2 |
| NCT00572169 | ACTIVE_NOT_RECRUITING | Multiple Myeloma |
University of Arkansas |
2006-11 | PHASE3 |
| NCT07673302 | RECRUITING | Thalassemia |
Riphah International University |
2026-06-20 | |
| NCT07187193 | RECRUITING | Langerhans Cell Histiocytosis |
Cancer Institute and Hospital, Chinese Academy of Medical Sciences |
2025-04-12 | PHASE2 |
| NCT07476625 | NOT_YET_RECRUITING | Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Adenitis Syndrome |
Wenjie Zheng |
2026-04-01 | |
| NCT06268093 | RECRUITING | Syringomyelia; Thalidomide |
Xuanwu Hospital, Beijing |
2024-02 | PHASE2 |
| NCT03069326 | ACTIVE_NOT_RECRUITING | Myelofibrosis |
Memorial Sloan Kettering Cancer Center |
2017-02-27 | PHASE2 |
| NCT07172659 | RECRUITING | Erythema Nodosum Leprosum |
Medicines Development for Global Health |
2026-09-15 | PHASE2 |
| NCT03004287 | ACTIVE_NOT_RECRUITING | Multiple Myeloma |
University of Arkansas |
2017-07-01 | PHASE2 |
| NCT03896737 | ACTIVE_NOT_RECRUITING | Multiple Myeloma |
European Myeloma Network B.V. |
2019-04-16 | PHASE2 |
| NCT06530576 | RECRUITING | T-LGL Leukemia; NK-LGL Leukemia |
Institute of Hematology & Blood Diseases Hospital, China |
2024-08-10 | PHASE2 |
| NCT06793475 | RECRUITING | Extramedullary Multiple Myeloma |
Institute of Hematology & Blood Diseases Hospital, China |
2025-04-09 | |
| NCT03562169 | RECRUITING | Multiple Myeloma |
University of Leeds |
2017-03-20 | PHASE3 |
| NCT06772480 | NOT_YET_RECRUITING | Liver Cirrhosis; Gastric Antral Vascular Ectasia |
Institute of Liver and Biliary Sciences, India |
2025-01-05 | |
| NCT06299670 | COMPLETED | Transfusion-dependent Thalassemia |
Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh |
2023-11-01 | PHASE4 |
| NCT06279351 | RECRUITING | Thalidomide Enhances Clinical Efficacy of Cetuximab Combined With Standard Chemotherapy for Left Colorectal Cancer |
Xinqiao Hospital of Chongqing |
2024-08-11 | PHASE2 |
| NCT04941937 | UNKNOWN | Multiple Myeloma |
Juan Du |
2022-01-27 | PHASE2 |
| NCT07292259 | COMPLETED | Transfusion Dependent Beta Thalassemia |
Pakistan Blood and Marrow Transplant (PBMT) Group |
2024-01-01 | PHASE2 |
| NCT06017284 | RECRUITING | Pancreatic Cancer Stage IV; Chemotherapy-induced Nausea and Vomiting |
Fudan University |
2023-11-01 | PHASE3 |
| NCT06276933 | NOT_YET_RECRUITING | Lung Cancer; Camrelizumab |
Tongji University |
2024-02-22 | PHASE4 |
| NCT06031012 | COMPLETED | Mucositis Oral |
Air Force Military Medical University, China |
2023-09-15 | PHASE3 |
| NCT03759093 | UNKNOWN | Multiple Myeloma |
National University Hospital, Singapore |
2023-09-10 | PHASE2; PHASE3 |
| NCT06490627 | RECRUITING | Fetal Hemoglobin; Thalassemia Major; Genetic Disease |
National Institute of Blood and Marrow Transplant (NIBMT), Pakistan |
2024-04-22 | PHASE2 |
| NCT06256627 | RECRUITING | Acute Myeloid Leukemia; Maintenance Treatment; Minor Residue Disease; Interferon-α-1b; Interleukin-2; Thalidomide; Venentoclax; Azacitidine |
Henan Cancer Hospital |
2023-07-11 | |
| NCT05527444 | UNKNOWN | Ankylosing Spondylitis |
Qilu Hospital of Shandong University |
2022-03-15 | PHASE4 |
| NCT06888232 | COMPLETED | Thalassemia |
Muhammad Aamir Latif |
2023-08-01 | |
| NCT04891744 | UNKNOWN | Multiple Myeloma |
Li Zheng |
2021-07-06 | PHASE1; PHASE2 |
| NCT06231680 | UNKNOWN | Lung Cancer, Nonsmall Cell; Esophageal Carcinoma |
Henan Cancer Hospital |
2024-01-19 | PHASE2 |
| NCT06470464 | COMPLETED | Germ Cell Tumor; Yolk Sac Tumor |
Shandong First Medical University |
2021-11-11 | PHASE2 |
| NCT06490601 | ACTIVE_NOT_RECRUITING | Fetal Hemoglobin; Beta-Thalassemia; Hemoglobinopathies |
National Institute of Blood and Marrow Transplant (NIBMT), Pakistan |
2022-04-01 | PHASE2 |
| NCT02891811 | COMPLETED | Multiple Myeloma |
Arbeitsgemeinschaft medikamentoese Tumortherapie |
2017-03-10 | PHASE2 |
| NCT05198856 | UNKNOWN | Gastric Cancer Metastatic to Liver |
Qilu Hospital of Shandong University |
2022-03-10 | PHASE1; PHASE2 |
| NCT06098014 | COMPLETED | Transfusion-dependent Thalassemia |
Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh |
2023-03-01 | PHASE1 |
| NCT04352205 | TERMINATED | Plasma Cell Myeloma; Renal Failure |
Emory University |
2020-05-07 | PHASE2 |
| NCT01661400 | COMPLETED | Glioma; Neuroectodermal Tumors, Primitive; Wilms Tumor; Rhabdomyosarcoma; Sarcoma, Ewing; Osteosarcoma; Retinoblastoma |
Washington University School of Medicine |
2012-10-26 | PHASE1 |
| NCT02586038 | COMPLETED | Multiple Myeloma |
Mario Boccadoro |
2015-10 | PHASE2 |
| NCT02507336 | COMPLETED | Mantle Cell Lymphoma; Non-Hodgkin's Lymphoma |
University of Miami |
2015-11-24 | PHASE2 |
| NCT06153784 | COMPLETED | Thalassemia, Beta |
Children's Hospital Karachi |
2020-07-07 | PHASE2; PHASE3 |
| NCT06146478 | COMPLETED | Transfusion-dependent Beta-Thalassemia |
Blood Care Clinic |
2022-01-25 | PHASE3 |
| NCT04453345 | UNKNOWN | T-LGL Leukemia; Clpd-Nk |
Institute of Hematology & Blood Diseases Hospital, China |
2013-05-20 | PHASE2; PHASE3 |
| NCT04612582 | UNKNOWN | Immunoglobulin Light-Chain Amyloidosis |
Guangdong Provincial People's Hospital |
2020-01-01 | PHASE4 |
| NCT05059613 | UNKNOWN | Oral Mucositis; Quality of Life |
Jiangxi Provincial Cancer Hospital |
2021-09-20 | |
| NCT05525234 | UNKNOWN | Haemodialysis; Uremic Pruritus; Thalidomide |
RenJi Hospital |
2022-09-15 | PHASE4 |
| NCT02085655 | UNKNOWN | Extranodal NK-T-Cell Lymphoma, Nasal and Nasal-Type |
Huiqiang Huang |
2013-04-25 | PHASE3 |
| NCT05266820 | UNKNOWN | Metastatic Colorectal Cancer |
Fujian Cancer Hospital |
2021-10-01 | PHASE2 |
| NCT03980002 | RECRUITING | Chronic Lymphocytic Leukemia |
Institute of Hematology & Blood Diseases Hospital, China |
2019-05-15 | PHASE2 |
| NCT04382300 | UNKNOWN | Non-small-cell Lung Cancer |
Shanghai Chest Hospital |
2020-06-30 | PHASE2 |
| NCT04680195 | UNKNOWN | Chronic Radiation Proctitis |
Sixth Affiliated Hospital, Sun Yat-sen University |
2020-12-14 | PHASE2 |
| NCT01659658 | TERMINATED | Relapsed or Refractory Systemic Light Chain Amyloidosis |
Millennium Pharmaceuticals, Inc. |
2012-12-26 | PHASE3 |
| NCT02461888 | COMPLETED | Multiple Myeloma |
University of Leeds |
2015-12 | PHASE2 |
| NCT06146478 | Completed | Transfusion-dependent Beta-Thalassemia |
Blood Care Clinic|Khyber Medical University Peshawar |
2022-01-25 | Phase 3 |
| NCT04120519 | UNKNOWN | Langerhans Cell Histiocytosis |
Peking Union Medical College Hospital |
2019-10-10 | PHASE2 |
| NCT06239389 | COMPLETED | Beta-Thalassemia |
National Institute of Blood and Marrow Transplant (NIBMT), Pakistan |
2021-09-01 | PHASE2 |
| NCT01554852 | UNKNOWN | Multiple Myeloma |
University of Leeds |
2010-05 | PHASE3 |
| NCT03651102 | COMPLETED | Thalassemia |
Blood Diseases Clinic |
2018-01-01 | PHASE2; PHASE3 |
| NCT03608501 | WITHDRAWN | Multiple Myeloma |
Takeda |
2019-09-30 | PHASE2 |
| NCT05132270 | COMPLETED | Thalassemia, Beta |
Children's Hospital Karachi |
2020-01-01 | PHASE2; PHASE3 |
| NCT03122431 | COMPLETED | Systemic Lupus Erythematosus (SLE); Juvenile SLE; Cutaneous Lupus |
University of Sao Paulo General Hospital |
2017-06-05 | PHASE4 |
| NCT04680195 | Unknown status | Chronic Radiation Proctitis |
Sixth Affiliated Hospital Sun Yat-sen University |
2020-12-14 | Phase 2 |
| NCT02870036 | UNKNOWN | Advanced Solid Tumor; Advanced/Metastatic Colorectal Cancer |
Haihe Biopharma Co., Ltd. |
2016-10 | PHASE1 |
| NCT02707484 | COMPLETED | Gastrointestinal Vascular Malformation |
Shanghai Jiao Tong University School of Medicine |
2016-04 | PHASE3 |
| NCT03062800 | UNKNOWN | Advanced Nsclc |
Qilu Hospital of Shandong University |
2016-12 | PHASE2 |
| NCT03777930 | UNKNOWN | Cancer, Therapy-Related |
Shenzhen Fifth People's Hospital |
2018-12-10 | PHASE4 |
| NCT04469556 | Active not recruiting | Pancreatic Cancer Metastatic|Pancreatic Ductal Adenocarcinoma|Advanced Pancreatic Cancer |
University Health Network Toronto|Johns Hopkins University|Cold Spring Harbor Laboratory|Ontario Institute for Cancer Research|Dana-Farber Cancer Institute|Memorial Sloan Kettering Cancer Center|Stand Up To Cancer |
2020-10-14 | Phase 2 |
| NCT01849783 | COMPLETED | Extramedullary Plasmacytoma; Isolated Plasmacytoma of Bone; Light Chain Deposition Disease; Primary Systemic Amyloidosis; Stage I Multiple Myeloma; Stage II Multiple Myeloma; Stage III Multiple Myeloma |
Margarida Magalhaes-Silverman |
2013-04-04 | PHASE2 |
| NCT02541383 | COMPLETED | Multiple Myeloma |
Intergroupe Francophone du Myelome |
2015-09 | PHASE3 |
| NCT03318835 | UNKNOWN | Thalidomide |
Fudan University |
2017-08-22 | PHASE3 |
| NCT03221166 | TERMINATED | Crohn Disease |
IRCCS Burlo Garofolo |
2018-02-27 | PHASE3 |
| NCT03601871 | UNKNOWN | Chemotherapy-induced Nausea and Vomiting |
Yunpeng Liu |
2018-07-12 | |
| NCT04273529 | UNKNOWN | COVID-19 Thalidomide |
First Affiliated Hospital of Wenzhou Medical University |
2020-02-20 | PHASE2 |
| NCT02733380 | UNKNOWN | Diffuse Large B-cell Lymphoma |
Henan Cancer Hospital |
2016-05 | PHASE2 |
| NCT03792620 | UNKNOWN | Multiple Myeloma Stage I |
Grupo de Estudos Multicentricos em Onco-Hematologia |
2018-11-20 | PHASE3 |
| NCT04273581 | UNKNOWN | COVID-19 Thalidomide |
First Affiliated Hospital of Wenzhou Medical University |
2020-02-18 | PHASE2 |
| NCT02424851 | COMPLETED | Multiple Myeloma; Chronic Kidney Disease |
Oxford University Hospitals NHS Trust |
2014-11 | PHASE2 |
| NCT03208413 | UNKNOWN | Radiation Injuries |
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University |
2017-07-19 | PHASE2 |
| NCT03043105 | UNKNOWN | Multicentric Castleman Disease |
Peking Union Medical College Hospital |
2017-01-01 | PHASE2 |
| NCT02858804 | COMPLETED | Mantle Cell Lymphoma |
Institute of Hematology & Blood Diseases Hospital, China |
2016-01 | PHASE4 |
| NCT03016000 | UNKNOWN | Lymphoma, Large B-Cell, Diffuse |
Nanfang Hospital, Southern Medical University |
2017-07-26 | PHASE3 |
| NCT03341494 | UNKNOWN | NSCLC Stage IV; Chemotherapy Effect |
Fujian Cancer Hospital |
2017-04-01 | PHASE2 |
| NCT02844309 | COMPLETED | Waldenström Macroglobulinemia |
Institute of Hematology & Blood Diseases Hospital, China |
2016-05 | PHASE4 |
| NCT02545907 | COMPLETED | Amyloidosis |
University College, London |
2017-09-14 | PHASE1; PHASE2 |
| NCT02248428 | UNKNOWN | Multiple Myeloma |
Jinling Hospital, China |
2012-04 | PHASE3 |
| NCT02966522 | UNKNOWN | Cardiac Amyloidosis |
Seoul National University Hospital |
2016-10 | PHASE2 |
| NCT03143036 | UNKNOWN | Relapse and / or Refractory Myeloma |
National University Hospital, Singapore |
2018-05-01 | PHASE2 |
| NCT03140943 | UNKNOWN | Relapsed and/or Refractory Multiple Myeloma |
National University Hospital, Singapore |
2017-09-13 | PHASE2 |
| NCT02879526 | UNKNOWN | Relapse/Refratory Peripheral T Cell Lymphoma |
The First Affiliated Hospital with Nanjing Medical University |
2016-08 | PHASE2 |
| NCT02410694 | COMPLETED | Multiple Myeloma |
Arbeitsgemeinschaft medikamentoese Tumortherapie |
2015-04 | PHASE2 |
| NCT03184844 | UNKNOWN | Thalassemia |
Xiao-Lin Yin |
2017-05-02 | PHASE2 |
| NCT01998971 | COMPLETED | Multiple Myeloma |
Janssen Research & Development, LLC |
2014-02-18 | PHASE1 |
| NCT06985134 | COMPLETED | Comparative Efficacy and Safety of Thalidomide and Sulfasalazine in Moderate to Severe Ankylosing Spondylitis: A Real-World Study From Bangladesh; Condition ...Moderate to Severe Axial Spondyloarthopathy |
Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh |
2017-01-01 | PHASE3 |
| NCT01125176 | COMPLETED | Chronic Lymphocytic Leukemia |
Weill Medical College of Cornell University |
2012-03-30 | PHASE2 |
| NCT02467647 | UNKNOWN | Multiple Myeloma |
Wuhan University |
2015-01 | PHASE1 |
| NCT02956538 | UNKNOWN | Crohn Disease |
Sixth Affiliated Hospital, Sun Yat-sen University |
2016-10 | EARLY_PHASE1 |
| NCT02559154 | UNKNOWN | Multiple Myeloma |
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine |
2010-07 | PHASE4 |
| NCT00966693 | COMPLETED | Recurrent Plasma Cell Myeloma; Refractory Plasma Cell Myeloma |
M.D. Anderson Cancer Center |
2009-08-25 | PHASE1; PHASE2 |
| NCT00777998 | COMPLETED | Multiple Myeloma |
Universitätsklinikum Hamburg-Eppendorf |
2008-10-14 | PHASE2 |
| NCT00004088 | COMPLETED | Multiple Myeloma and Plasma Cell Neoplasm |
City of Hope Medical Center |
1999-04-13 | PHASE2 |
| NCT02748772 | UNKNOWN | Colorectal Neoplasms |
The First People's Hospital of Hefei |
2016-01 | PHASE3 |
| NCT02995707 | UNKNOWN | Thalassemia |
Xiao-Lin Yin |
2016-09 | PHASE2 |
| NCT02998827 | UNKNOWN | Crohn Disease |
Sixth Affiliated Hospital, Sun Yat-sen University |
2016-11 | |
| NCT03204032 | UNKNOWN | Extrapancreatic Neuroendocrine Tumor |
Chinese Academy of Medical Sciences |
2016-10 | PHASE2 |
| NCT03204019 | UNKNOWN | Pancreatic Neuroendocrine Tumor |
Chinese Academy of Medical Sciences |
2016-10 | PHASE2 |
| NCT02649101 | UNKNOWN | Metastatic Breast Cancer |
Zhejiang Cancer Hospital |
2015-10 | PHASE2 |
| NCT02387086 | UNKNOWN | NSCLC |
Bai Jun |
2015-05 | PHASE2; PHASE3 |
| NCT00892346 | SUSPENDED | Multiple Myeloma |
Shanghai Jiao Tong University School of Medicine |
2009-05 | PHASE3 |
| NCT02778893 | UNKNOWN | NSCLC |
Henan Provincial People's Hospital |
2016-03 | PHASE4 |
| NCT02447679 | COMPLETED | Adult Hepatocellular Carcinoma; Recurrent Hepatocellular Carcinoma; Adverse Reaction to Drug; Vascular Endothelial Growth Factor Overexpression |
Chang Gung Memorial Hospital |
2010-08 | PHASE2 |
| NCT01927718 | TERMINATED | Myeloma |
M.D. Anderson Cancer Center |
2014-01 | |
| NCT02401971 | UNKNOWN | Gastric Cancer |
Wang Jufeng |
2014-08 | PHASE4 |
| NCT00689936 | COMPLETED | Multiple Myeloma |
Celgene |
2008-08-21 | PHASE3 |
| NCT02203253 | COMPLETED | Neoplasms |
China Medical University, China |
2014-07 | PHASE3 |
| NCT01664975 | COMPLETED | Peripheral T-cell Lymphoma |
Mingzhi Zhang |
2011-08 | PHASE4 |
| NCT01551641 | UNKNOWN | Esophageal Cancer |
Changzhou No.2 People's Hospital |
2012-01 | PHASE2 |
| NCT01242267 | COMPLETED | Multiple Myeloma |
Hackensack Meridian Health |
2010-05-11 | PHASE1; PHASE2 |
| NCT01539083 | COMPLETED | Multiple Myeloma |
Janssen Scientific Affairs, LLC |
2012-01-13 | PHASE3 |
| NCT02301949 | WITHDRAWN | Gastrointestinal Bleeding of Unknown Origin; Gastrointestinal Vascular Malformation; Thalidomide Efficiency |
Zhizheng Ge |
2015-12 | PHASE2 |
| NCT01526694 | COMPLETED | Multiple Myeloma |
Azienda Ospedaliera di Bolzano |
2012-07 | PHASE2 |
| NCT01937442 | COMPLETED | Multiple Myeloma |
Celgene |
2013-11-07 | PHASE1 |
| NCT01971658 | COMPLETED | Multiple Myeloma |
Nantes University Hospital |
2013-10 | PHASE3 |
| NCT01924624 | UNKNOWN | Hepatocellular Carcinoma; Recurrence |
The First Affiliated Hospital of Xiamen University |
2013-07 | |
| NCT00450801 | COMPLETED | Lymphoma |
University of Miami |
2004-04 | PHASE2 |
| NCT02145715 | UNKNOWN | Multiple Myeloma |
Prof Jamie Cavenagh |
2013-01 | PHASE1; PHASE2 |
| NCT01638078 | UNKNOWN | Coronary Artery Disease |
University of Roma La Sapienza |
2014-01 | PHASE4 |
| NCT02501291 | COMPLETED | Crohn's Disease |
First Affiliated Hospital, Sun Yat-Sen University |
2013-01 | PHASE2 |
| NCT02201043 | COMPLETED | Ankylosing Spondylitis |
Shanghai Pharmaceuticals Holding Co., Ltd |
2013-02 | PHASE2 |
| NCT01976195 | WITHDRAWN | Immune Thrombocytopenia |
Shandong University |
2013-10 | PHASE2 |
| NCT02240771 | UNKNOWN | Hepatocellular Carcinoma |
All India Institute of Medical Sciences |
2006-01 | PHASE2; PHASE3 |
| NCT01485224 | COMPLETED | Hereditary Hemorrhagic Telangiectasia; Epistaxis |
Fondazione IRCCS Policlinico San Matteo di Pavia |
2011-11 | PHASE2 |
| NCT00081939 | COMPLETED | Multiple Myeloma |
University of Arkansas |
2004-01 | PHASE2 |
| NCT00112502 | COMPLETED | Brain and Central Nervous System Tumors; Glioblastoma Multiforme |
M.D. Anderson Cancer Center |
2005-09 | PHASE2 |
| NCT00083551 | COMPLETED | Multiple Myeloma |
University of Arkansas |
1998-08 | PHASE3 |
| NCT01063179 | COMPLETED | Multiple Myeloma |
Fondazione EMN Italy Onlus |
2006-05 | PHASE3 |
| NCT03402295 | COMPLETED | Multiple Myeloma; Effects of Chemotherapy |
Grupo de Estudos Multicentricos em Onco-Hematologia |
2009-06-15 | PHASE3 |
| NCT01633281 | TERMINATED | Peripheral Neuropathy Grade 2 or Greater |
Singapore General Hospital |
2012-06 | PHASE2 |
| NCT00083382 | COMPLETED | Multiple Myeloma |
University of Arkansas |
1998-12 | PHASE2 |
| NCT00792142 | COMPLETED | Multiple Myeloma and Plasma Cell Neoplasm; Neurotoxicity |
City of Hope Medical Center |
2008-01-16 | PHASE2 |
| NCT02754960 | WITHDRAWN | Gastrointestinal Hemorrhage; Vascular Malformation |
Shanghai Jiao Tong University School of Medicine |
2010-03 | PHASE2 |
| NCT01057225 | COMPLETED | Multiple Myeloma; Stage I Multiple Myeloma; Stage II Multiple Myeloma; Stage III Multiple Myeloma |
Mayo Clinic |
2010-03 | PHASE1; PHASE2 |
| NCT01537861 | TERMINATED | Multiple Myeloma |
Washington University School of Medicine |
2012-06 | EARLY_PHASE1 |
| NCT00602641 | ACTIVE_NOT_RECRUITING | Multiple Myeloma |
National Cancer Institute (NCI) |
2008-02-29 | PHASE3 |
| NCT00256776 | TERMINATED | Multiple Myeloma |
European Society for Blood and Marrow Transplantation |
2005-07 | PHASE3 |
| NCT01640639 | UNKNOWN | Congestive Heart Failure |
University of Roma La Sapienza |
2012-07 | PHASE4 |
| NCT01756989 | COMPLETED | Brainstem Glioma |
Helsinki University Central Hospital |
2005-01 | PHASE2 |
| NCT01632150 | COMPLETED | Relapsed and/or Refractory Multiple Myeloma |
Bristol-Myers Squibb |
2012-05 | PHASE2 |
| NCT01779167 | TERMINATED | Waldenstrom Macroglobulinemia |
Weill Medical College of Cornell University |
2012-06 | PHASE2 |
| NCT01438450 | UNKNOWN | Hepatocellular Carcinoma |
All India Institute of Medical Sciences |
2007-10 | PHASE2; PHASE3 |
| NCT01548573 | TERMINATED | Multiple Myeloma |
University of Iowa |
2012-05 | PHASE2 |
| NCT00507416 | COMPLETED | Multiple Myeloma |
Millennium Pharmaceuticals, Inc. |
2007-06 | PHASE3 |
| NCT00357500 | COMPLETED | Central Nervous System Tumor, Pediatric; Leukemia; Lymphoma; Neuroblastoma; Sarcoma; Unspecified Childhood Solid Tumor, Protocol Specific |
Dana-Farber Cancer Institute |
2005-01 | PHASE2 |
| NCT00025506 | COMPLETED | Recurrent Uterine Corpus Sarcoma; Uterine Carcinosarcoma |
National Cancer Institute (NCI) |
2001-09 | PHASE2 |
| NCT00379353 | COMPLETED | Advanced Cancers |
M.D. Anderson Cancer Center |
2006-09 | PHASE2 |
| NCT01094340 | UNKNOWN | Alzheimer's Disease |
Banner Health |
2010-03 | PHASE2; PHASE3 |
| NCT00934739 | TERMINATED | Oral Cavity Cancer |
National Health Research Institutes, Taiwan |
2007-06 | PHASE2; PHASE3 |
| NCT00921531 | UNKNOWN | Hepatocellular Carcinoma |
Fudan University |
2009-06 | PHASE3 |
| NCT00215943 | TERMINATED | Multiple Myeloma |
H. Lee Moffitt Cancer Center and Research Institute |
2003-06 | PHASE3 |
| NCT00075829 | COMPLETED | Multiple Myeloma |
National Heart, Lung, and Blood Institute (NHLBI) |
2003-12 | PHASE3 |
| NCT01249690 | UNKNOWN | Multiple Myeloma |
Second Military Medical University |
2010-06 | PHASE4 |
| NCT00064337 | COMPLETED | Multiple Myeloma; Plasma Cell Myeloma |
SWOG Cancer Research Network |
2004-01 | PHASE2 |
| NCT00958854 | UNKNOWN | Lymphoma |
Cancer Research UK |
2006-01 | PHASE2 |
| NCT01114048 | UNKNOWN | Multiple Myeloma |
Chonnam National University Hospital |
2010-03 | PHASE2 |
| NCT00527657 | COMPLETED | Brain Neoplasms; Melanoma |
M.D. Anderson Cancer Center |
2006-02-09 | PHASE1 |
| NCT00307294 | COMPLETED | Prostate Cancer |
University of Pittsburgh |
2006-03 | PHASE2 |
| NCT00089609 | COMPLETED | Prostatic Neoplasms |
National Cancer Institute (NCI) |
2005-04-19 | PHASE2 |
| NCT01532856 | UNKNOWN | Multiple Myeloma |
Grupo de Estudos Multicentricos em Onco-Hematologia |
2007-01 | PHASE3 |
| NCT00049673 | COMPLETED | Multiple Myeloma and Plasma Cell Neoplasm |
NCIC Clinical Trials Group |
2002-10-15 | PHASE3 |
| NCT00089544 | TERMINATED | Recurrent Adult Soft Tissue Sarcoma; Stage I Adult Soft Tissue Sarcoma AJCC v7; Stage II Adult Soft Tissue Sarcoma AJCC v7; Stage III Adult Soft Tissue Sarcoma AJCC v7 |
National Cancer Institute (NCI) |
2004-06-17 | PHASE2 |
| NCT00600028 | COMPLETED | Idiopathic Pulmonary Fibrosis; Cough |
Johns Hopkins University |
2007-12 | PHASE3 |
| NCT00720538 | COMPLETED | Inflammatory Bowel Diseases; Crohn's Disease; Ulcerative Colitis |
IRCCS Burlo Garofolo |
2008-08 | PHASE3 |
| NCT00523848 | COMPLETED | Multiple Myeloma and Plasma Cell Neoplasm |
Roswell Park Cancer Institute |
2006-06 | PHASE2 |
| NCT01055301 | WITHDRAWN | Multiple Myeloma; Plasma Cell Myeloma |
SWOG Cancer Research Network |
2011-07 | PHASE2 |
| NCT00310076 | COMPLETED | Carcinoma of the Appendix; Colorectal Cancer |
Wake Forest University Health Sciences |
2002-10 | PHASE2 |
| NCT00432458 | COMPLETED | Multiple Myeloma and Plasma Cell Neoplasm |
Mayo Clinic |
2003-07 | PHASE3 |
| NCT00389935 | COMPLETED | Arteriovenous Malformation; Hereditary Hemorrhagic Telangiectasia; Hematochezia; Melena |
Northport Veterans Affairs Medical Center |
2006-10 | PHASE2 |
| NCT00458705 | COMPLETED | Multiple Myeloma and Plasma Cell Neoplasm |
Memorial Sloan Kettering Cancer Center |
2006-11 | PHASE2 |
| NCT00574080 | TERMINATED | Multiple Myeloma |
University of Arkansas |
2006-07 | PHASE3 |
| NCT00041080 | COMPLETED | Fallopian Tube Cancer; Primary Peritoneal Cavity Cancer; Recurrent Ovarian Epithelial Cancer; Stage III Ovarian Epithelial Cancer; Stage IV Ovarian Epithelial Cancer |
National Cancer Institute (NCI) |
2003-02 | PHASE3 |
| NCT00907452 | COMPLETED | Myeloma |
Intergroupe Francophone du Myelome |
2009-07-29 | |
| NCT00890188 | UNKNOWN | Colon Cancer |
National Cheng-Kung University Hospital |
2009-01 | PHASE2 |
| NCT00096018 | COMPLETED | Leukemia |
Roswell Park Cancer Institute |
2002-05 | PHASE1; PHASE2 |
| NCT00287872 | COMPLETED | Multiple Myeloma |
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins |
2004-09 | PHASE2 |
| NCT00538824 | TERMINATED | Multiple Myeloma |
Weill Medical College of Cornell University |
2007-12 | PHASE2 |
| NCT00602511 | COMPLETED | Multiple Myeloma |
Nordic Myeloma Study Group |
2007-10 | PHASE3 |
| NCT00704704 | UNKNOWN | Myelodysplastic Syndrome |
Tel-Aviv Sourasky Medical Center |
2008-09 | PHASE2 |
| NCT00406978 | COMPLETED | Multiple Myeloma |
Silvio Aime |
2006-02 | PHASE1; PHASE2 |
| NCT00519688 | COMPLETED | Hepatocellular Carcinoma |
National Taiwan University Hospital |
2006-07 | PHASE2 |
| NCT00538733 | COMPLETED | Multiple Myeloma |
Weill Medical College of Cornell University |
2007-10 | PHASE2 |
| NCT00098865 | COMPLETED | Central Nervous System Tumor, Pediatric; Neuroblastoma |
Dana-Farber Cancer Institute |
2002-09 | PHASE2 |
| NCT00083915 | COMPLETED | Multiple Myeloma |
University of Arkansas |
2001-06 | PHASE3 |
| NCT00124813 | UNKNOWN | Multiple Myeloma |
University Hospital, Bonn |
2002-08 | PHASE2 |
| NCT00723658 | WITHDRAWN | Lymphoma |
SWOG Cancer Research Network |
2008-09 | PHASE2 |
| NCT00505635 | TERMINATED | Melanoma |
M.D. Anderson Cancer Center |
2007-03 | PHASE2 |
| NCT00075023 | TERMINATED | Graft-versus-Host Disease; Stomatitis |
National Institute of Nursing Research (NINR) |
2003-12 | PHASE2 |
| NCT00090870 | TERMINATED | Kidney Cancer |
Medical University of South Carolina |
2002-04 | PHASE2 |
| NCT00652041 | COMPLETED | Multiple Myeloma |
PETHEMA Foundation |
2007-01 | PHASE4 |
| NCT00971126 | TERMINATED | Hepatocellular Carcinoma |
National Health Research Institutes, Taiwan |
2009-07 | PHASE1; PHASE2 |
| NCT00787436 | WITHDRAWN | Gastrointestinal Hemorrhage; Portal Hypertension |
The Cleveland Clinic |
2006-05 | PHASE3 |
| NCT00004859 | TERMINATED | Lung Cancer |
National Cancer Institute (NCI) |
2000-01 | PHASE3 |
| NCT00151281 | COMPLETED | Non-Hodgkin's Lymphoma |
Weill Medical College of Cornell University |
2004-11 | PHASE2 |
| NCT00412542 | COMPLETED | Glioblastoma Multiforme; Glioma |
M.D. Anderson Cancer Center |
2003-10 | PHASE2 |
| NCT00222053 | COMPLETED | Multiple Myeloma |
University Hospital, Toulouse |
2000-04 | PHASE3 |
| NCT00934154 | COMPLETED | Multiple Myeloma |
Cigdem Sahinbas YILMAZ |
2006-03 | PHASE3 |
| NCT01028781 | TERMINATED | Endometriosis |
University of North Carolina, Chapel Hill |
2006-10 | PHASE1 |
| NCT00910897 | UNKNOWN | Multiple Myeloma |
Intergroupe Francophone du Myelome |
2008-03 | PHASE3 |
| NCT00728078 | UNKNOWN | Hepatocellular Carcinoma; Liver Cancer |
Sun Yat-sen University |
2008-07 | PHASE2; PHASE3 |
| NCT00856804 | UNKNOWN | Hepatitis C |
Valme University Hospital |
2009-03 | PHASE2 |
| NCT00047879 | COMPLETED | Glioma |
National Cancer Institute (NCI) |
2002-10 | PHASE2 |
| NCT00953615 | TERMINATED | Primary Sclerosing Cholangitis |
Mayo Clinic |
2006-04 | PHASE2 |
| NCT00276705 | UNKNOWN | Liver Cancer |
Children's Cancer and Leukaemia Group |
2005-06 | PHASE2 |
| NCT00577668 | WITHDRAWN | Multiple Myeloma |
University of Arkansas |
2007-04 | PHASE2 |
| NCT00531453 | COMPLETED | Multiple Myeloma |
Millennium Pharmaceuticals, Inc. |
2007-10 | PHASE2 |
| NCT00222105 | COMPLETED | Multiple Myeloma |
University of Kansas Medical Center |
2002-11 | PHASE2 |
| NCT00373646 | COMPLETED | MALT Lymphoma |
Medical University of Vienna |
2006-06 | PHASE2 |
| NCT00452569 | COMPLETED | Multiple Myeloma |
Celgene |
2006-02-01 | PHASE3 |
| NCT00529633 | TERMINATED | Hypoalbuminemia |
George A. Kaysen, M.D. |
2007-09 | PHASE3 |
| NCT00019747 | TERMINATED | Colorectal Cancer |
National Institutes of Health Clinical Center (CC) |
1999-08 | PHASE2 |
| NCT00461747 | COMPLETED | Multiple Myeloma |
PETHEMA Foundation |
2006-03 | PHASE3 |
| NCT00438841 | UNKNOWN | Multiple Myeloma and Plasma Cell Neoplasm |
Fred Hutchinson Cancer Center |
2006-08 | PHASE2 |
| NCT00098475 | ACTIVE_NOT_RECRUITING | DS Stage I Multiple Myeloma; DS Stage II Multiple Myeloma; DS Stage III Multiple Myeloma |
National Cancer Institute (NCI) |
2004-11-03 | PHASE3 |
| NCT00263484 | COMPLETED | Multiple Myeloma |
Gleneagles Hospital |
2005-12 | PHASE2 |
| NCT00040937 | COMPLETED | Multiple Myeloma |
SWOG Cancer Research Network |
2002-06 | PHASE2 |
| NCT00450008 | TERMINATED | Prostatic Neoplasms |
The Methodist Hospital Research Institute |
2006-12 | PHASE2 |
| NCT01134484 | UNKNOWN | Multiple Myeloma |
Michele Cavo |
2006-05 | PHASE3 |
| NCT00573391 | TERMINATED | Multiple Myeloma |
University of Arkansas |
2006-08 | PHASE3 |
| NCT01296503 | COMPLETED | Multiple Myeloma |
Grupo de Estudos Multicentricos em Onco-Hematologia |
2003-10 | PHASE3 |
| NCT00124579 | TERMINATED | Multiple Myeloma |
SWOG Cancer Research Network |
2005-08 | PHASE2 |
| NCT00400517 | COMPLETED | Prostate Cancer |
The Cleveland Clinic |
2003-03 | PHASE2 |
| NCT00258245 | COMPLETED | Multiple Myeloma and Plasma Cell Neoplasm |
Barbara Ann Karmanos Cancer Institute |
2005-05 | PHASE1 |
| NCT00961467 | COMPLETED | Multiple Myeloma |
Fondazione EMN Italy Onlus |
2007-02 | PHASE2 |
| NCT00281827 | TERMINATED | Lung Cancer |
Masonic Cancer Center, University of Minnesota |
2002-05 | PHASE2 |
| NCT00320476 | COMPLETED | Multiple Myeloma |
Korean Multiple Myeloma Working Party |
2006-04 | PHASE2 |
| NCT00006226 | COMPLETED | B-cell Chronic Lymphocytic Leukemia; Refractory Chronic Lymphocytic Leukemia |
National Cancer Institute (NCI) |
2000-09 | PHASE2 |
| NCT00083005 | COMPLETED | Prostate Cancer |
National Institutes of Health Clinical Center (CC) |
2004-03 | PHASE2 |
| NCT00083538 | COMPLETED | Multiple Myeloma |
University of Arkansas |
2001-02 | PHASE2 |
| NCT00089167 | COMPLETED | Multiple Myeloma and Plasma Cell Neoplasm |
Memorial Sloan Kettering Cancer Center |
2002-05 | PHASE2 |
| NCT00015821 | COMPLETED | Primary Myelofibrosis |
National Cancer Institute (NCI) |
2000-05 | PHASE2 |
| NCT00083460 | COMPLETED | Multiple Myeloma |
University of Arkansas |
2001-12 | PHASE1 |
| NCT00964496 | COMPLETED | Obscure Gastrointestinal Bleeding; Angiodysplasia; Gastric Antral Vascular Ectasia; Thalidomide |
Shanghai Jiao Tong University School of Medicine |
2004-11 | PHASE2 |
| NCT00469703 | TERMINATED | Chronic Pancreatitis |
Winthrop University Hospital |
2005-08 | PHASE2 |
| NCT00305552 | COMPLETED | Sarcoidosis |
Assistance Publique - Hôpitaux de Paris |
2005-02 | PHASE3 |
| NCT01341262 | COMPLETED | Multiple Myeloma |
IRCCS Azienda Ospedaliero-Universitaria di Bologna |
2002-03 | PHASE2 |
| NCT00097981 | COMPLETED | Multiple Myeloma |
Johnson & Johnson Pharmaceutical Research & Development, L.L.C. |
2005-01 | PHASE3 |
| NCT00031941 | COMPLETED | Lymphoma; Small Intestine Cancer; Unspecified Adult Solid Tumor, Protocol Specific |
National Institutes of Health Clinical Center (CC) |
2002-04 | PHASE1 |
| NCT00274820 | COMPLETED | Chronic Myeloproliferative Disorders; Leukemia; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Diseases |
Case Comprehensive Cancer Center |
2005-10 | PHASE2 |
| NCT00633542 | COMPLETED | Multiple Myeloma |
Università Politecnica delle Marche |
2003-06 | PHASE3 |
| NCT00039468 | COMPLETED | Brain and Central Nervous System Tumors |
Dartmouth-Hitchcock Medical Center |
2002-03 | PHASE2 |
| NCT00025467 | COMPLETED | Endometrial Adenoacanthoma; Endometrial Adenocarcinoma; Endometrial Adenosquamous Cell Carcinoma; Endometrial Clear Cell Carcinoma; Endometrial Papillary Serous Carcinoma; Recurrent Endometrial Carcinoma |
National Cancer Institute (NCI) |
2001-09 | PHASE2 |
| NCT00104988 | COMPLETED | Melanoma (Skin) |
SWOG Cancer Research Network |
2005-06 | PHASE2 |
| NCT00114192 | COMPLETED | Lung Cancer |
University of Virginia |
2004-06 | PHASE2 |
| NCT01061866 | COMPLETED | Refractory Epilepsy |
National Institute of Neurology and Neurosurgery, Mexico |
2006-06 | PHASE1; PHASE2 |
| NCT00046826 | COMPLETED | Prostate Cancer |
Nuvance Health |
2001-09 | PHASE2 |
| NCT00218855 | COMPLETED | Multiple Myeloma |
Norwegian University of Science and Technology |
2002-01 | PHASE3 |
| NCT00182663 | COMPLETED | Refractory Multiple Myeloma; Stage I Multiple Myeloma; Stage II Multiple Myeloma; Stage III Multiple Myeloma |
Fred Hutchinson Cancer Center |
2003-06 | PHASE2 |
| NCT00443235 | COMPLETED | Multiple Myeloma |
PETHEMA Foundation |
2005-03 | PHASE3 |
| NCT00061919 | COMPLETED | Lung Cancer |
University College, London |
2003-04 | PHASE3 |
| NCT00015990 | COMPLETED | Chronic Myelomonocytic Leukemia; de Novo Myelodysplastic Syndromes; Previously Treated Myelodysplastic Syndromes; Refractory Anemia; Refractory Anemia With Excess Blasts; Refractory Anemia With Excess Blasts in Transformation; Refractory Anemia With Ringed Sideroblasts; Secondary Myelodysplastic Syndromes |
National Cancer Institute (NCI) |
2001-04 | PHASE2 |
| NCT00053287 | COMPLETED | Leukemia; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Diseases |
Case Comprehensive Cancer Center |
2002-09 | PHASE2 |
| NCT00301405 | TERMINATED | Chronic Prostatitis; Pelvic Pain |
Kenneth Peters, MD |
2006-03 | PHASE2 |
| NCT00009984 | TERMINATED | Recurrent Small Lymphocytic Lymphoma; Refractory Chronic Lymphocytic Leukemia |
National Cancer Institute (NCI) |
2002-03 | PHASE2 |
| NCT00165451 | COMPLETED | Neoplasms |
Dana-Farber Cancer Institute |
2001-06 | PHASE2 |
| NCT00025519 | WITHDRAWN | Kidney Cancer |
Fox Chase Cancer Center |
2001-06 | PHASE2 |
| NCT00445900 | COMPLETED | Chronic Myeloproliferative Disorders; Secondary Myelofibrosis |
Mayo Clinic |
2004-10 | PHASE2 |
| NCT00111748 | COMPLETED | Multiple Myeloma |
University of Arkansas |
2005-02 | PHASE3 |
| NCT00072163 | COMPLETED | Recurrent Melanoma; Stage IV Melanoma; Tumors Metastatic to Brain |
National Cancer Institute (NCI) |
2003-10 | PHASE2 |
| NCT00165230 | COMPLETED | Neuroendocrine Tumor |
Dana-Farber Cancer Institute |
2002-05 | PHASE2 |
| NCT00251797 | COMPLETED | Brain and Nervous System; Cancer |
University of New Mexico |
2000-03 | PHASE1 |
| NCT00033254 | COMPLETED | Tumors Metastatic to Brain |
National Cancer Institute (NCI) |
2002-03 | PHASE3 |
| NCT00062127 | COMPLETED | Unspecified Adult Solid Tumor, Protocol Specific |
National Cancer Institute (NCI) |
2003-04 | PHASE1 |
| NCT00057564 | COMPLETED | Multiple Myeloma |
Celgene Corporation |
2003-02 | PHASE3 |
| NCT00054158 | COMPLETED | Multiple Myeloma and Plasma Cell Neoplasm |
Roswell Park Cancer Institute |
2004-08 | PHASE2 |
| NCT00079092 | COMPLETED | Brain and Central Nervous System Tumors |
Wake Forest University Health Sciences |
2004-01-01 | PHASE2 |
| NCT00033332 | COMPLETED | Multiple Myeloma and Plasma Cell Neoplasm |
National Cancer Institute (NCI) |
2002-04 | PHASE3 |
| NCT00005966 | COMPLETED | Kidney Cancer |
Eastern Cooperative Oncology Group |
2000-10 | PHASE3 |
| NCT00227682 | TERMINATED | Multiple Myeloma and Plasma Cell Neoplasm |
OHSU Knight Cancer Institute |
2004-06 | PHASE2 |
| NCT00008242 | COMPLETED | Multiple Myeloma and Plasma Cell Neoplasm |
Memorial Sloan Kettering Cancer Center |
2000-08 | PHASE2 |
| NCT00250796 | COMPLETED | Liver; Cancer |
University of New Mexico |
2000-09 | PHASE2 |
| NCT00049374 | COMPLETED | Multiple Myeloma and Plasma Cell Neoplasm |
University of Maryland, Baltimore |
2002-09 | PHASE2 |
| NCT00238329 | COMPLETED | Intraocular Melanoma; Melanoma (Skin) |
Barbara Ann Karmanos Cancer Institute |
2001-01 | PHASE2 |
| NCT00165217 | COMPLETED | Colorectal Adenocarcinoma |
Dana-Farber Cancer Institute |
2001-11 | PHASE2 |
| NCT00038181 | COMPLETED | Prostate Cancer |
M.D. Anderson Cancer Center |
2000-10-05 | PHASE2 |
| NCT00053300 | COMPLETED | Lung Cancer |
Case Comprehensive Cancer Center |
2002-08 | PHASE2 |
| NCT00657488 | COMPLETED | Multiple Myeloma |
Celgene |
2001-12-01 | PHASE2; PHASE3 |
| NCT00193544 | COMPLETED | Multiple Myeloma |
SCRI Development Innovations, LLC |
2002-03 | PHASE2 |
| NCT01891019 | COMPLETED | Psoriasis, Plaque-type |
Wake Forest University |
2003-04 | PHASE2 |
| NCT00053430 | COMPLETED | HIV Infections |
National Institute of Allergy and Infectious Diseases (NIAID) |
2001-04 | PHASE2 |
| NCT00047281 | COMPLETED | Brain and Central Nervous System Tumors |
Dana-Farber Cancer Institute |
2004-03 | PHASE2 |
| NCT00277017 | COMPLETED | Kidney; Cancer |
New Mexico Cancer Research Alliance |
2000-09 | PHASE1; PHASE2 |
| NCT00226980 | COMPLETED | Kidney Neoplasms |
Stanford University |
2002-10 | PHASE2 |
| NCT00038090 | COMPLETED | Multiple Myeloma |
M.D. Anderson Cancer Center |
2000-06 | PHASE2; PHASE3 |
| NCT00006016 | COMPLETED | Adult Primary Hepatocellular Carcinoma; Advanced Adult Primary Liver Cancer; Localized Unresectable Adult Primary Liver Cancer |
National Cancer Institute (NCI) |
2000-05 | PHASE2 |
| NCT00038233 | COMPLETED | Multiple Myeloma |
M.D. Anderson Cancer Center |
1999-05 | PHASE3 |
| NCT00006006 | COMPLETED | Liver Cancer |
National Cancer Institute (NCI) |
2000-08 | PHASE2 |
| NCT00047294 | COMPLETED | Brain and Central Nervous System Tumors |
Dana-Farber Cancer Institute |
2001-04 | PHASE2 |
| NCT00193102 | TERMINATED | Breast Cancer |
SCRI Development Innovations, LLC |
2001-04 | PHASE2 |
| NCT00004635 | COMPLETED | Prostate Cancer |
National Cancer Institute (NCI) |
2000-03-01 | PHASE3 |
| NCT00232934 | COMPLETED | Multiple Myeloma |
Gruppo Italiano per lo Studio del Mieloma Multiplo |
2002-01 | PHASE3 |
| NCT00049361 | COMPLETED | Brain and Central Nervous System Tumors; Unspecified Adult Solid Tumor, Protocol Specific |
Wake Forest University Health Sciences |
2004-01-01 | PHASE2 |
| NCT00022581 | COMPLETED | Recurrent Grade 1 Follicular Lymphoma; Recurrent Grade 2 Follicular Lymphoma; Recurrent Grade 3 Follicular Lymphoma; Recurrent Small Lymphocytic Lymphoma |
National Cancer Institute (NCI) |
2001-07 | PHASE2 |
| NCT00049296 | COMPLETED | Cancer |
Case Comprehensive Cancer Center |
2002-07 | PHASE1 |
| NCT00025285 | COMPLETED | Lung Cancer |
Wake Forest University Health Sciences |
2001-11-01 | PHASE2 |
| NCT00005815 | COMPLETED | Intraocular Melanoma; Melanoma (Skin) |
Memorial Sloan Kettering Cancer Center |
1999-12 | PHASE1; PHASE2 |
| NCT00072345 | COMPLETED | Intraocular Melanoma; Melanoma (Skin) |
Memorial Sloan Kettering Cancer Center |
2003-07 | PHASE2 |
| NCT00201357 | COMPLETED | Hormone-refractory Prostate Cancer |
National Health Research Institutes, Taiwan |
2002-10 | PHASE2 |
| NCT00577096 | COMPLETED | Multiple Myeloma |
University of Arkansas |
2001-10 | |
| NCT00016224 | COMPLETED | Ovarian Cancer |
Memorial Sloan Kettering Cancer Center |
2001-01 | PHASE2 |
| NCT00038246 | COMPLETED | Prostate Cancer |
M.D. Anderson Cancer Center |
2000-10 | PHASE1; PHASE2 |
| NCT00142116 | COMPLETED | Waldenstrom's Macroglobulinemia; Lymphoplasmacytic Lymphoma |
Steven P. Treon, MD, PhD |
2003-05 | PHASE2 |
| NCT00027638 | COMPLETED | Gastrointestinal Carcinoid Tumor; Islet Cell Tumor; Lung Cancer; Neoplastic Syndrome |
Memorial Sloan Kettering Cancer Center |
2001-03 | PHASE2 |
| NCT00005834 | TERMINATED | Multiple Myeloma |
SWOG Cancer Research Network |
2000-04 | PHASE3 |
| NCT00026533 | COMPLETED | Head and Neck Cancer |
Kenneth Ain |
2001-06 | PHASE2 |
| NCT00017316 | COMPLETED | Melanoma (Skin) |
National Cancer Institute (NCI) |
2001-03 | PHASE2 |
| NCT00015912 | TERMINATED | Recurrent Grade 1 Follicular Lymphoma; Recurrent Grade 2 Follicular Lymphoma |
National Cancer Institute (NCI) |
2001-07 | PHASE2 |
| NCT00014443 | TERMINATED | Brain and Central Nervous System Tumors |
Rush University Medical Center |
2000-08 | PHASE2 |
| NCT00003850 | COMPLETED | Head and Neck Cancer |
National Cancer Institute (NCI) |
1999-04 | PHASE2 |
| NCT00030550 | COMPLETED | Leukemia; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Neoplasms |
Roswell Park Cancer Institute |
2001-09 | PHASE2 |
| NCT00025220 | COMPLETED | Recurrent Uterine Corpus Sarcoma; Uterine Corpus Leiomyosarcoma |
National Cancer Institute (NCI) |
2001-09 | PHASE2 |
| NCT00006358 | COMPLETED | Brain and Central Nervous System Tumors |
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins |
2000-06-13 | PHASE2 |
| NCT00006890 | COMPLETED | Multiple Myeloma and Plasma Cell Neoplasm |
NCIC Clinical Trials Group |
2000-07-12 | PHASE2 |
| NCT00003754 | COMPLETED | Unspecified Childhood Solid Tumor, Protocol Specific |
Memorial Sloan Kettering Cancer Center |
1998-09 | PHASE2 |
| NCT00003894 | COMPLETED | Graft Versus Host Disease; Unspecified Adult Solid Tumor, Protocol Specific; Unspecified Childhood Solid Tumor, Protocol Specific |
Roswell Park Cancer Institute |
1999-03 | PHASE2 |
| NCT00027664 | UNKNOWN | Kidney Cancer |
Cancer Research UK |
2001-02 | PHASE2 |
| NCT00052416 | COMPLETED | Leukemia; Lymphoma |
Beth Israel Deaconess Medical Center |
2002-10 | PHASE1 |
| NCT00083876 | COMPLETED | Multiple Myeloma |
University of Arkansas |
1998-09 | PHASE3 |
| NCT00083577 | COMPLETED | Multiple Myeloma |
University of Arkansas |
1998-02 | PHASE2 |
| NCT00022607 | COMPLETED | Multiple Myeloma and Plasma Cell Neoplasm |
California Cancer Consortium |
2002-01 | PHASE2 |
| NCT00140452 | COMPLETED | Amyotrophic Lateral Sclerosis; ALS |
Dartmouth-Hitchcock Medical Center |
2005-02 | PHASE2 |
| NCT00050843 | COMPLETED | Myelodysplastic Syndromes |
Celgene Corporation |
2001-08 | PHASE3 |
| NCT00121563 | COMPLETED | Pain |
National Institute of Nursing Research (NINR) |
2005-07 | PHASE2 |
| NCT00001446 | COMPLETED | Prostatic Neoplasm |
National Cancer Institute (NCI) |
1995-09 | PHASE2 |
| NCT00000790 | COMPLETED | HIV Infections; Stomatitis, Aphthous |
National Institute of Allergy and Infectious Diseases (NIAID) |
PHASE2 | |
| NCT00081757 | COMPLETED | Multiple Myeloma |
University of Arkansas |
1998-09 | PHASE1; PHASE2 |
| NCT00644306 | TERMINATED | Newly Diagnosed, Multiple Myeloma |
Central Hospital, Nancy, France |
2002-04 | PHASE3 |
| NCT00001599 | COMPLETED | Sjogren's Syndrome; Xerostomia |
National Institute of Dental and Craniofacial Research (NIDCR) |
1997-05 | PHASE2 |
| NCT00036894 | COMPLETED | Brain and Central Nervous System Tumors |
National Cancer Institute (NCI) |
2002-03 | PHASE1 |
| NCT00358020 | COMPLETED | Multiple Myeloma |
University of Turin, Italy |
2004-11 | PHASE2 |
| NCT00026520 | COMPLETED | Melanoma (Skin) |
SWOG Cancer Research Network |
2001-11 | PHASE2 |
| NCT00271804 | TERMINATED | Myelodysplastic Syndrome |
Massachusetts General Hospital |
2005-06 | PHASE1 |
| NCT00006200 | UNKNOWN | Melanoma |
National Center for Research Resources (NCRR) |
PHASE2 | |
| NCT00390247 | WITHDRAWN | Peritoneal Dialysis; Malnutrition |
Chinese University of Hong Kong |
2007-01 | PHASE4 |
| NCT00378755 | UNKNOWN | Multiple Myeloma |
Korean Multiple Myeloma Working Party |
2006-03 | PHASE2 |
| NCT00004276 | COMPLETED | HIV Infections; Mycobacterium Infections; Tuberculosis |
National Center for Research Resources (NCRR) |
1990-09 | PHASE2 |
| NCT00209014 | TERMINATED | B-Cell Lymphoma; Hodgkin's Disease |
Emory University |
2003-07 | PHASE2 |
| NCT00000812 | COMPLETED | HIV Infections |
National Institute of Allergy and Infectious Diseases (NIAID) |
PHASE1 | |
| NCT00083707 | COMPLETED | Waldenstrom Macroglobulinemia |
University of Arkansas |
1999-01 | PHASE2 |
| NCT00033709 | UNKNOWN | Sarcoma |
Herbert Irving Comprehensive Cancer Center |
2002-03 | PHASE2 |
| NCT00455910 | COMPLETED | Myelodysplastic Syndromes |
Groupe Francophone des Myelodysplasies |
2003-01 | PHASE2 |
| NCT00521482 | UNKNOWN | Glioblastoma |
University of Zurich |
2007-09 | PHASE2 |
| NCT00006005 | COMPLETED | Endometrial Cancer; Sarcoma |
New York University Cancer Institute |
2000-09 | PHASE2 |
| NCT00418132 | TERMINATED | Scleroderma, Systemic |
NYU Langone Health |
2000-08 | PHASE1 |
| NCT00028886 | UNKNOWN | Multiple Myeloma and Plasma Cell Neoplasm |
Commissie Voor Klinisch Toegepast Onderzoek |
2001-03 | PHASE3 |
| NCT00002104 | COMPLETED | Mycobacterium Avium-Intracellulare Infection; HIV Infections; Tuberculosis, Mycobacterium Infection |
Aaron Diamond AIDS Research Center |
PHASE1 | |
| NCT00349115 | UNKNOWN | Multiple Myeloma |
Korean Multiple Myeloma Working Party |
2006-06 | PHASE2 |
| NCT00231140 | TERMINATED | Amyotrophic Lateral Sclerosis (ALS) |
Charite University, Berlin, Germany |
2005-12 | PHASE2 |
| NCT00002157 | COMPLETED | HIV Infections; HIV Wasting Syndrome |
Celgene Corporation |
||
| NCT00083694 | COMPLETED | Leukemia |
University of Arkansas |
1998-08 | PHASE2 |
| NCT00155272 | UNKNOWN | Hepatocellular Carcinoma |
National Taiwan University Hospital |
2005-03 | PHASE1; PHASE2 |
| NCT00225290 | TERMINATED | Carcinoma, Hepatocellular |
TTY Biopharm |
2003-02 | PHASE3 |
| NCT00284505 | COMPLETED | Arachnoiditis |
Washington University School of Medicine |
2005-07 | PHASE2 |
| NCT00001475 | COMPLETED | Acquired Immunodeficiency Syndrome; HIV Infection |
National Institute of Allergy and Infectious Diseases (NIAID) |
1995-06 | PHASE2 |
| NCT01274403 | COMPLETED | Multiple Myeloma |
Gruppo Italiano Studio Linfomi |
PHASE2 | |
| NCT00004876 | COMPLETED | Ovarian Cancer |
Cancer Research UK |
1999-08 | PHASE2 |
| NCT00053001 | COMPLETED | Anemia; Leukemia; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Neoplasms |
Fallon Clinic |
2001-06 | PHASE2 |
| NCT00083408 | COMPLETED | Multiple Myeloma |
University of Arkansas |
1998-03 | PHASE2 |
| NCT00026416 | UNKNOWN | Sarcoma |
Herbert Irving Comprehensive Cancer Center |
2001-10 | PHASE2 |
| NCT00205751 | COMPLETED | Multiple Myeloma |
Austrian Forum Against Cancer |
2001-08 | PHASE2; PHASE3 |
| NCT01527032 | COMPLETED | Amyloidosis |
FDA Office of Orphan Products Development |
2002-09 | PHASE2 |
| NCT00319865 | UNKNOWN | Multiple Myeloma |
Korean Multiple Myeloma Working Party |
2005-11 | PHASE2 |
| NCT00083902 | COMPLETED | Multiple Myeloma |
University of Arkansas |
1998-06 | PHASE2 |
| NCT00058487 | COMPLETED | Liver Cancer |
Dana-Farber Cancer Institute |
2001-12 | PHASE2 |
| NCT00019539 | COMPLETED | Stage IV Renal Cell Cancer; Recurrent Renal Cell Cancer |
National Cancer Institute (NCI) |
1998-11 | PHASE2 |
| NCT00001524 | COMPLETED | Acquired Immunodeficiency Syndrome; Burning Mouth Syndrome; HIV Infection |
National Institute of Dental and Craniofacial Research (NIDCR) |
1996-06 | PHASE2 |
| NCT00001680 | COMPLETED | Discoid Lupus Erythematosus |
National Cancer Institute (NCI) |
1997-10 | PHASE2 |
| NCT00004450 | COMPLETED | Adrenoleukodystrophy |
FDA Office of Orphan Products Development |
1998-08 | |
| NCT00314665 | TERMINATED | Uveitis |
University of Cincinnati |
2004-01 | PHASE4 |
| NCT00002127 | COMPLETED | HIV Infections; HIV Wasting Syndrome |
Celgene Corporation |
PHASE2 | |
| NCT00367185 | COMPLETED | Multiple Myeloma |
University Hospital, Lille |
2000-05 | PHASE3 |
| NCT00002174 | COMPLETED | HIV Infections |
Louisiana State University Health Sciences Center in New Orleans |
||
| NCT00019123 | COMPLETED | Sarcoma |
National Cancer Institute (NCI) |
1996-04 | PHASE2 |
| NCT00112879 | WITHDRAWN | Stage I Multiple Myeloma; Stage II Multiple Myeloma; Stage III Multiple Myeloma; Refractory Plasma Cell Neoplasm |
The Cleveland Clinic |
PHASE2 | |
| NCT00020046 | COMPLETED | Stage IV Prostate Cancer; Adenocarcinoma of the Prostate; Recurrent Prostate Cancer |
National Institutes of Health Clinical Center (CC) |
1999-12 | PHASE2 |
| NCT01070862 | COMPLETED | Multiple Myeloma de Novo Treatment |
University Hospital, Caen |
2003-05 | PHASE3 |
| NCT00162760 | COMPLETED | Idiopathic Pulmonary Fibrosis (IPF) |
Johns Hopkins University |
2003-10 | PHASE2 |
| NCT00002392 | COMPLETED | HIV Infections |
Rockefeller University |
||
| NCT00083681 | COMPLETED | Multiple Myeloma |
University of Arkansas |
1998-06 | PHASE2 |
| NCT00006198 | UNKNOWN | Liver Cancer |
National Center for Research Resources (NCRR) |
PHASE2 | |
| NCT00384800 | UNKNOWN | Carcinoma, Hepatocellular |
Far Eastern Memorial Hospital |
2006-09 | PHASE2 |
| NCT00023530 | COMPLETED | Bone Marrow Transplantation; Blood Disease; Hematopoietic Stem Cell Transplantation; Leukemia; Multiple Myeloma; Myelodysplastic Syndromes; Graft vs Host Disease |
National Heart, Lung, and Blood Institute (NHLBI) |
2001-09 |
(data from https://clinicaltrials.gov, updated on 2025-12-30)
Check the
Thalidomide
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Mechanism and Biochemical Profile
Appendix RUO and cGMP Quality Standards
| Quality Dimension | RUO (Research Use Only) | cGMP (Current Good Manufacturing Practice) |
|---|---|---|
| Clinical Applicability | Prohibited in human clinical trials or medical diagnostics. | Mandatory for human clinical trials (Phase I–III) and therapies. |
| Regulatory Status | Non-regulated grade; exempt from drug manufacturing laws. | Legally enforced by health authorities (e.g., FDA, EMA, NMPA). |
| Facility Environment | Unclassified analytical or research laboratories. | Validated Cleanrooms (ISO Class 5–8) with continuous monitoring. |
| Quality Control | Basic purity and activity testing. | Rigorous safety release testing (Sterility, Endotoxin, Mycoplasma). |
| Process Validation | Basic equipment calibration; no process validation required. | Full qualification (IQ/OQ/PQ) and complete batch records. |
| Quality Assurance | Vendor self-declared without required formal QMS. | Mandatory QA/QC unit, Change Control, CAPA, and vendor audits. |
| Regulatory Impact | High risk of IND rejection if used as a critical raw material. | Required for IND/NDA filings, supported by Drug Master Files (DMF). |
Footnotes
Regulatory Note: Governed by FDA (21 CFR Parts 210/211/312), EMA (EudraLex Vol 4), ICH Guidelines (E6/Q7/Q9/Q10), and compendial standards (USP <71>/<85>/<1043>).
Note: Technical data last updated: Sep 1, 2026.