CAS No. 568-72-9

Batch: Purity:99.85
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Tanshinone IIA Chemical Structure
Chemical Structure
Check the Tanshinone IIA product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name 1,6,6-trimethyl-8,9-dihydro-7H-naphtho[1,2-g][1]benzofuran-10,11-dione
CAS Number 568-72-9
Molecular Formula

C19H18O3
Molecular Weight (MW) 294.34
InChIKey HYXITZLLTYIPOF-UHFFFAOYSA-N

Ordering Information

Biological Activity

Tanshinone IIA is a natural diterpene quinone and monoacylglycerol lipase inhibitor derived from Salvia miltiorrhiza that exhibits anti-inflammatory and antitumor activities. Treatment with Tanshinone IIA suppresses the NF-kB signaling pathway, reducing the expression of inflammatory mediators. Additionally, it triggers reactive oxygen species generation and mitochondrial depolarization, subsequently inducing apoptosis and cell death across multiple tumor cell lines. [1]

Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 1 mg/mL (3.39 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)
Water Insoluble
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.