CAS No. 1069-66-5

Batch: Purity:98.55
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Sodium Valproate (Valproic acid sodium) Chemical Structure
Chemical Structure
Check the Sodium Valproate (Valproic acid sodium) product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name sodium 2-propylpentanoate
CAS Number 1069-66-5
Molecular Formula

C8H15NaO2
Molecular Weight (MW) 166.19
SMILES CCCC(CCC)C(=O)[O-].[Na+]
InChIKey AEQFSUDEHCCHBT-UHFFFAOYSA-M

Ordering Information

Biological Activity

Sodium Valproate (Valproic acid sodium) is a histone deacetylase (HDAC) inhibitor that exhibits anticancer, neuroprotective, and anticonvulsant activities. It induces G0/G1 phase cell cycle arrest and cell apoptosis in cancer cells while increasing GABA levels and modulating neuronal firing. Furthermore, Sodium Valproate enables the reprogramming of somatic cells into pluripotent stem cells in combination with Oct4 and Sox2. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
Water 100 mg/mL
DMSO 33 mg/mL (198.56 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 33 mg/mL
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.