CAS No. 156-54-7
Batch:
Purity:100.00
Chemical Structure
Check the
Sodium butyrate
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | sodium butanoate | |
|---|---|---|
| CAS Number | 156-54-7 | |
| Molecular Formula |
C4H7NaO2 |
|
| Molecular Weight (MW) | 110.09 | |
| SMILES | CCCC(=O)[O-].[Na+] | |
| InChIKey | MFBOGIVSZKQAPD-UHFFFAOYSA-M |
Sodium butyrate is a histone deacetylase (HDAC) inhibitor that competitively binds to the zinc sites of class I and class II HDACs. By inhibiting HDAC activity, it induces histone hyperacetylation, modulates gene transcription, and alters chromatin structure. Downstream cellular effects include inhibition of cell cycle progression, promotion of cell differentiation, and induction of apoptosis and autophagy in various cancer cell types. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| Water | 22 mg/mL |
| Ethanol | 8 mg/mL |
| DMSO |
Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
| Water | 22 mg/mL |
| Ethanol | 22 mg/mL |
| DMSO |
Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
| Water | 100 mg/mL (超声助溶) |
| Ethanol | 18 mg/mL |
| DMSO |
Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
| Water | 22 mg/mL |
| DMSO |
Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
| Ethanol | Insoluble |
| Water | 100 mg/mL (超声助溶) |
| Ethanol | 11 mg/mL |
| DMSO |
Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
Note: Technical data last updated: Sep 1, 2026.