CAS No. 119302-91-9

Batch: Purity:99.78
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Rocuronium Bromide Chemical Structure
Chemical Structure
Check the Rocuronium Bromide product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name [(2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-3-hydroxy-10,13-dimethyl-2-morpholin-4-yl-16-(1-prop-2-enylpyrrolidin-1-ium-1-yl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl] acetate bromide
CAS Number 119302-91-9
Molecular Formula

C32H53N2O4.Br
Molecular Weight (MW) 609.68
SMILES CC(=O)OC1C(CC2C1(CCC3C2CCC4C3(CC(C(C4)O)N5CCOCC5)C)C)[N+]6(CCCC6)CC=C.[Br-]
InChIKey OYTJKRAYGYRUJK-FMCCZJBLSA-M

Ordering Information

Biological Activity

Rocuronium Bromide is an aminosteroid non-depolarizing neuromuscular blocker that acts as a competitive antagonist of nicotinic acetylcholine receptors (nAChRs). By binding competitively to cholinergic receptors at the neuromuscular junction, it blocks acetylcholine signal transmission across the motor endplate. This inhibition suppresses postsynaptic depolarization, leading to skeletal muscle relaxation and neuromuscular blockade.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 122 mg/mL (200.1 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 122 mg/mL
Ethanol 122 mg/mL
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.