Clinical Trials

Numerous clinical trials and observational studies evaluate ritonavir across Phase 1 to Phase 4, focusing predominantly on HIV infections, COVID-19, chronic hepatitis delta, and hepatitis C. Sponsored by pharmaceutical corporations, government entities, and academic institutions, these initiatives span planned, active, and completed recruitment stages. Ultimately, these studies evaluate ritonavir's pharmacokinetic boosting capabilities and therapeutic efficacy across varied indications.

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT06337032 RECRUITING
HIV-1-infection
Gilead Sciences
2024-08-27 PHASE4
NCT07792096 NOT_YET_RECRUITING
HIV Infection
University College, London
2026-11 PHASE3
NCT04381936 RECRUITING
Pneumonia
University of Oxford
2020-03-19 PHASE3
NCT02140255 RECRUITING
HIV Infection
National Institute of Allergy and Infectious Diseases (NIAID)
2015-01-23 PHASE1; PHASE2
NCT07601074 RECRUITING
Human Papilloma Virus (HPV); High-risk Human Papillomavirus Infection
Daré Bioscience, Inc.
2026-07-17 PHASE2
NCT05334004 RECRUITING
High-Grade Anal Intraepithelial Neoplasia
University of Wisconsin, Madison
2023-12-19 PHASE1
NCT05041907 RECRUITING
COVID-19
University of Oxford
2021-09-30 PHASE2
NCT05261139 RECRUITING
COVID-19
Pfizer
2022-03-07 PHASE3
NCT02735707 RECRUITING
Community-acquired Pneumonia, Influenza, COVID-19
UMC Utrecht
2016-04-11 PHASE3
NCT06792214 RECRUITING
SARS CoV-2 Post-Acute Sequelae
Mount Sinai Hospital, Canada
2025-01-03 PHASE4
NCT05852873 ACTIVE_NOT_RECRUITING
Post COVID-19 Condition, Unspecified; SARS-CoV2 Infection; COVID-19
Haukeland University Hospital
2023-05-12 PHASE3
NCT04483960 UNKNOWN
SARS-CoV-2 Infection (COVID-19)
University of Melbourne
2020-07-28 PHASE3
NCT06139796 WITHDRAWN
HIV Infections
PENTA Foundation
2025-02-01 PHASE1; PHASE2
NCT05938140 UNKNOWN
COVID-19; Renal Insufficiency, Chronic
Chinese PLA General Hospital
2023-06-22 PHASE4
NCT05386472 TERMINATED
COVID-19
Pfizer
2022-06-22 PHASE1
NCT04022967 UNKNOWN
HIV-1-infection
ANRS, Emerging Infectious Diseases
2020-09-21 PHASE3
NCT06397144 Not yet recruiting
Biological Availability|Healthy Participants
Pfizer
2025-02-14 Phase 1
NCT05925140 UNKNOWN
COVID-19; Hospitalized COVID-19 Patients
Lebanese University
2020-03-28 PHASE1
NCT05823896 COMPLETED
Post-COVID-19 Syndrome; Long COVID; Long Covid19; COVID-19; POTS - Postural Orthostatic Tachycardia Syndrome; Post COVID-19 Condition; Post-COVID Syndrome; Post COVID-19 Condition, Unspecified; Postinfectious Inflammation; Postinfectious Disorder
Karolinska Institutet
2023-05-01 PHASE2
NCT06139796 Not yet recruiting
HIV Infections
PENTA Foundation|AMS-PHPT Research Collaboration|Institut National de la Santé Et de la Recherche Médicale France|Centre Mère et Enfant de la Fondation Chantal Biya|Centre Hospitalier National d''Enfants Albert Royer|University of Zimbabwe Clinical Research Centre (UZCRC)|Baylor College of Medicine
2024-06 Phase 1|Phase 2
NCT05953545 WITHDRAWN
Chronic Hepatitis Delta
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
2024-05-22 PHASE2
NCT05953545 Not yet recruiting
Chronic Hepatitis Delta
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)|National Institutes of Health Clinical Center (CC)
2024-05-15 Phase 2
NCT06291831 Active not recruiting
COVID-19
Pfizer
2024-03-13 --
NCT05441215 COMPLETED
Healthy Participants
Pfizer
2022-12-12 PHASE1
NCT05731804 UNKNOWN
Renal Impairment; Hepatic Impairment
Jiangsu Simcere Pharmaceutical Co., Ltd.
2023-03-01 PHASE1
NCT06085924 Recruiting
COVID-19
Pfizer
2023-11-14 --
NCT05321394 COMPLETED
COVID-19
Azienda Ospedaliera Universitaria Integrata Verona
2022-03-07 PHASE3
NCT06016556 Completed
Covid-19
Pfizer
2023-10-17 --
NCT05826249 UNKNOWN
Elder
Jiangsu Simcere Pharmaceutical Co., Ltd.
2023-04-07 PHASE1
NCT05545319 WITHDRAWN
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2); Coronavirus Disease 2019 (COVID-19); Immunocompromised; Hospitalization; Child, Hospitalized
Pfizer
2022-12-13 PHASE2
NCT05898672 COMPLETED
Pharmacokinetics; Healthy Volunteers
Pfizer
2023-06-09 PHASE1
NCT06087055 COMPLETED
Healthy Participant
Fujian Akeylink Biotechnology Co., Ltd.
2023-05-12 PHASE1
NCT05656443 COMPLETED
COVID-19 Pneumonia
Fujian Akeylink Biotechnology Co., Ltd.
2022-12-19 PHASE2; PHASE3
NCT05690646 COMPLETED
Cardiac Surgery
China National Center for Cardiovascular Diseases
2023-01-28 PHASE4
NCT06205329 COMPLETED
Healthy Participants
Westlake Pharmaceuticals (Hangzhou) Co., Ltd.
2022-10-03 PHASE1
NCT05506176 COMPLETED
COVID-19
Jiangsu Simcere Pharmaceutical Co., Ltd.
2022-08-19 PHASE2; PHASE3
NCT05544786 COMPLETED
Biological Availability
Pfizer
2022-09-28 PHASE1
NCT02437110 COMPLETED
Amyotrophic Lateral Sclerosis
National Institute of Neurological Disorders and Stroke (NINDS)
2019-04-01 PHASE1
NCT05692570 COMPLETED
Drug-drug Interaction
Pyramid Biosciences
2022-09-09 PHASE1
NCT03017872 UNKNOWN
HIV Infections
Kirby Institute
2017-11-23 PHASE4
NCT05525910 COMPLETED
Biological Availability; Healthy Participants
Pfizer
2022-08-31 PHASE1
NCT05373446 UNKNOWN
COVID-19
Jiangsu Simcere Pharmaceutical Co., Ltd.
2022-05-20 PHASE2
NCT03719313 COMPLETED
Hepatitis Delta Virus
Eiger BioPharmaceuticals
2018-12-01 PHASE3
NCT05339646 UNKNOWN
Healthy Participants
Jiangsu Simcere Pharmaceutical Co., Ltd.
2022-04-07 PHASE1
NCT05369676 COMPLETED
COVID-19 Patients
Jiangsu Simcere Pharmaceutical Co., Ltd.
2022-05-12 PHASE1; PHASE2
NCT05829551 COMPLETED
COVID-19 (Coronavirus Disease 2019)
Guangdong Raynovent Biotech Co., Ltd
2022-05-20 PHASE1
NCT05011513 TERMINATED
COVID-19
Pfizer
2021-08-25 PHASE2; PHASE3
NCT04147208 COMPLETED
Chronic HBV Infection
Sunshine Lake Pharma Co., Ltd.
2019-02-28 PHASE2
NCT05366192 COMPLETED
Safety Issues
RenJi Hospital
2022-05-06 PHASE4
NCT05601167 COMPLETED
COVID-19
Promomed, LLC
2021-02-17 PHASE3
NCT05263921 COMPLETED
Bioavailability
Pfizer
2022-03-10 PHASE1
NCT05263895 COMPLETED
Bioavailability
Pfizer
2022-03-03 PHASE1
NCT05339334 COMPLETED
Healthy Participants
Pfizer
2022-03-10 PHASE1
NCT05047601 COMPLETED
COVID-19
Pfizer
2021-09-09 PHASE2; PHASE3
NCT03602690 UNKNOWN
HIV/AIDS
ANRS, Emerging Infectious Diseases
2018-10-04 PHASE2
NCT05011812 COMPLETED
Covid19
Pardes Biosciences, Inc.
2021-08-14 PHASE1
NCT04390152 TERMINATED
Acute Respiratory Distress Syndrome
BioXcellerator
2020-01-13 PHASE1; PHASE2
NCT05032950 COMPLETED
Healthy Participants
Pfizer
2021-09-17 PHASE1
NCT05005312 COMPLETED
Hepatic Impairment
Pfizer
2021-08-31 PHASE1
NCT04499677 COMPLETED
COVID-19
University College, London
2020-09-24 PHASE2
NCT04466241 COMPLETED
COVID-19; COVID-19 Drug Treatment; Severe Acute Respiratory Syndrome Coronavirus 2
ANRS, Emerging Infectious Diseases
2020-11-27 PHASE2; PHASE3
NCT04455958 WITHDRAWN
Hematopoietic and Lymphoid Cell Neoplasm; Malignant Solid Neoplasm; Symptomatic COVID-19 Infection Laboratory-Confirmed
OHSU Knight Cancer Institute
2021-05-01 PHASE2
NCT04630002 COMPLETED
HIV Infections
ViiV Healthcare
2020-10-28 PHASE1
NCT04229290 COMPLETED
HIV-1-infection
University of Nairobi
2020-02-12 PHASE4
NCT04380818 UNKNOWN
Pneumonia, Viral
Grupo de Investigación Clínica en Oncología Radioterapia
2020-06-05
NCT04321174 UNKNOWN
Coronavirus Infections; Post-exposure Prophylaxis
Unity Health Toronto
2020-04-17 PHASE3
NCT01281813 COMPLETED
HIV-1 Infections
Janssen Sciences Ireland UC
2011-08-08 PHASE3
NCT04385719 COMPLETED
Ebola; HIV/AIDS
Makerere University
2021-05-05 PHASE2
NCT04459702 WITHDRAWN
COVID; COVID-19; Corona Virus Infection; Coronavirus Infection; Coronavirus Sars-Associated as Cause of Disease Classified Elsewhere; Coronavirus-19; SARS-CoV 2; SARS Pneumonia
ProgenaBiome
2020-07 PHASE2
NCT02219490 COMPLETED
Chronic Hepatitis C Virus (HCV) Infection Genotype 1
AbbVie
2014-10-30 PHASE3
NCT04459286 TERMINATED
Covid-19
Obafemi Awolowo University
2020-10-09 PHASE2
NCT02555943 COMPLETED
Chronic Hepatitis C Infection; HBV Coinfection; Hepatitis B Reactivation
Humanity and Health Research Centre
2015-02 PHASE2; PHASE3
NCT04208061 COMPLETED
Healthy
Janssen Research & Development, LLC
2019-12-18 PHASE1
NCT02968641 WITHDRAWN
Chronic Delta Hepatitis
Eiger BioPharmaceuticals
PHASE2
NCT04403100 UNKNOWN
COVID-19; Coronavirus Infection; Virus Disease; Acute Respiratory Infection; SARS-CoV Infection
Cardresearch
2020-06-03 PHASE3
NCT04251871 UNKNOWN
Pneumonia Caused by Human Coronavirus (Disorder)
Beijing 302 Hospital
2020-01-22
NCT03988452 UNKNOWN
Human Immunodeficiency Virus
Makerere University
2019-07-30 PHASE3
NCT04295551 UNKNOWN
COVID-19
Jiangxi Qingfeng Pharmaceutical Co. Ltd.
2020-03-14
NCT04255017 UNKNOWN
2019-nCoV
Tongji Hospital
2020-02-01 PHASE4
NCT04261270 UNKNOWN
2019-nCoV Pneumonia
Tongji Hospital
2020-02-01 PHASE3
NCT02845843 COMPLETED
Middle East Respiratory Syndrome Coronavirus (MERS-CoV)
King Abdullah International Medical Research Center
2016-07 PHASE2; PHASE3
NCT04307693 TERMINATED
COVID-19
Asan Medical Center
2020-03-11 PHASE2
NCT04343768 COMPLETED
COVID-19
Shahid Beheshti University of Medical Sciences
2020-04-09 PHASE2
NCT04350684 UNKNOWN
COVID-19
Shahid Beheshti University of Medical Sciences
2020-04-15 PHASE4
NCT04331470 UNKNOWN
COVID-19
Fasa University of Medical Sciences
2020-04-04 PHASE2; PHASE3
NCT04376814 COMPLETED
COVID-19; Favipiravir; Kaletra; Hydroxychloroquine; Lopinavir/Ritonavir
Baqiyatallah Medical Sciences University
2020-03-29
NCT05084456 WITHDRAWN
Solid Tumor, Adult; Impaired Liver Function
Modra Pharmaceuticals
2017-07 PHASE1
NCT02337322 UNKNOWN
Acquired Immune Deficiency Syndrome Virus
Juan A. Arnaiz
2015-03-31 PHASE4
NCT03589027 UNKNOWN
HIV-1-infection; Contraception
Makerere University
2018-08-07 PHASE2
NCT02150993 COMPLETED
HIV-2 Infection
ANRS, Emerging Infectious Diseases
2016-01-26 PHASE2; PHASE3
NCT03549832 COMPLETED
HCV Coinfection
Assiut University
2018-01-01
NCT01792570 COMPLETED
Human Immunodeficiency Virus
ASST Fatebenefratelli Sacco
2014-09-30 PHASE3
NCT03362814 COMPLETED
HCV
Ascletis Pharmaceuticals Co., Ltd.
2017-07-01 PHASE2; PHASE3
NCT03892161 TERMINATED
HIV Infections
University of Cape Town
2018-04-12 PHASE1
NCT02652793 COMPLETED
Human Immunodeficiency Virus
Judit Pich
2015-11
NCT02874066 COMPLETED
Hepatitis Viruses
National Taiwan University Hospital
2017-03-13 PHASE4
NCT03485846 COMPLETED
Chronic Hepatitis C Genotype 1b
R-Pharm
2017-11-27 PHASE2
NCT03499639 COMPLETED
End-stage Renal Disease; HCV Coinfection
Assiut University
2018-05-01 PHASE4
NCT03662568 COMPLETED
Chronic Hepatitis B
Sunshine Lake Pharma Co., Ltd.
2018-06-26 PHASE1
NCT02806362 WITHDRAWN
Chronic Hepatitis C Virus
AbbVie
2016-09 PHASE3
NCT02194998 TERMINATED
HIV Infections; Hepatitis C
National Institute of Allergy and Infectious Diseases (NIAID)
2015-09-16 PHASE2
NCT01125696 COMPLETED
HIV; Hepatitis B
Centers for Disease Control and Prevention
2012-05 PHASE2
NCT02369965 COMPLETED
HIV Infections; AIDS
Frontier Biotechnologies Inc.
2014-02-19 PHASE3
NCT02646111 UNKNOWN
Hepatitis C
Tel-Aviv Sourasky Medical Center
2016-01 PHASE3
NCT03708861 WITHDRAWN
HIV Infection
University of Turin, Italy
2016-01 PHASE3
NCT02473328 COMPLETED
HIV-1 Infection
Centre de Recherches et d'Etude sur la Pathologie Tropicale et le Sida
2015-06 PHASE2
NCT01138605 COMPLETED
HIV-1 Infections
Janssen Sciences Ireland UC
2010-10-13 PHASE2
NCT03234036 COMPLETED
Infection, Human Immunodeficiency Virus; HIV Infections
GlaxoSmithKline
2017-08-02 PHASE1
NCT01923311 TERMINATED
Acquired Immune Deficiency Syndrome (AIDS); HIV Infections
Gilead Sciences
2013-08-26 PHASE2; PHASE3
NCT02652624 COMPLETED
HIV-1 Infection
Gilead Sciences
2016-02-19 PHASE3
NCT04378608 COMPLETED
Hepatitis C Virus Infection
Beni-Suef University
2017-01-05 PHASE1; PHASE2
NCT02735863 COMPLETED
HIV Infection
Abivax S.A.
2016-05 PHASE2
NCT02770508 COMPLETED
HIV-1 Infection
Fundación Huésped
2015-11 PHASE4
NCT02470650 WITHDRAWN
Patient Compliance; Antiretroviral Therapy Intolerance
Juan A. Arnaiz
2015-06 PHASE4
NCT02430194 COMPLETED
Chronic Hepatitis D Infection
Eiger BioPharmaceuticals
2014-12 PHASE2
NCT02511431 COMPLETED
Hepatitis D
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
2015-07-29 PHASE2
NCT01601626 TERMINATED
HIV Infection; Tuberculosis
Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
2013-07-13 PHASE2
NCT02503462 TERMINATED
AIDS-related Dementia Complex
University Hospital, Basel, Switzerland
2015-07 PHASE4
NCT02207088 COMPLETED
Chronic Hepatitis C; Hepatitis C Virus; Compensated Cirrhosis; Severe Renal Impairment; End-stage Renal Disease
AbbVie
2014-09-23 PHASE3
NCT02795754 COMPLETED
Infection, Human Immunodeficiency Virus
GlaxoSmithKline
2016-03 PHASE1
NCT01869634 COMPLETED
Human Immunodeficiency Virus Infection
University of California, Davis
2013-06 PHASE4
NCT01782495 COMPLETED
Chronic Hepatitis C Infection
AbbVie
2013-02-25 PHASE2
NCT03020004 COMPLETED
Chronic Hepatitis C
Ascletis Pharmaceuticals Co., Ltd.
2016-01 PHASE2
NCT02609659 COMPLETED
Hepatitis C Virus (HCV)
AbbVie
2015-10-28 PHASE3
NCT02517515 COMPLETED
Hepatitis C Virus (HCV)
AbbVie
2015-07 PHASE3
NCT01773070 COMPLETED
Hepatitis C
AbbVie (prior sponsor, Abbott)
2013-06 PHASE3
NCT01061151 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
2011-03-01 PHASE3
NCT02517528 COMPLETED
Chronic Hepatitis C Virus (HCV)
AbbVie
2015-07-20 PHASE3
NCT02582632 COMPLETED
Hepatitis C Infection; Hepatitis C Virus
AbbVie
2015-11-24 PHASE3
NCT03020134 COMPLETED
Healthy
Ascletis Pharmaceuticals Co., Ltd.
2016-07-15 PHASE1
NCT00855335 COMPLETED
HIV; HIV Infections; Pregnancy
Janssen Scientific Affairs, LLC
2009-04-09 PHASE3
NCT02265237 COMPLETED
Hepatitis C Virus
AbbVie
2014-10-28 PHASE3
NCT01939197 COMPLETED
Hepatitis C Virus Infection; Human Immunodeficiency Virus Infection; Chronic Hepatitis C; Compensated Cirrhosis and Non-cirrhotics
AbbVie
2013-08-30 PHASE2; PHASE3
NCT02198443 COMPLETED
HIV
Fundacion Clinic per a la Recerca Biomédica
2015-06-06 PHASE4
NCT02442271 COMPLETED
Chronic Hepatitis C Infection
AbbVie
2015-04-27 PHASE3
NCT02219672 UNKNOWN
AIDS/HIV PROBLEM
Peking Union Medical College
2014-07 PHASE3
NCT01632891 COMPLETED
HIV-1 Infection; Pf Subclinical Parasitemia
Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
2014-01-10 PHASE1; PHASE2
NCT02542852 COMPLETED
HIV-1 Infection
Castagna Antonella
2015-09 PHASE2
NCT01599364 COMPLETED
Human Immunodeficiency Virus
Catholic University of the Sacred Heart
2014-04 PHASE4
NCT02159599 COMPLETED
HIV Infection
Fundacion SEIMC-GESIDA
2014-07 PHASE4
NCT02493855 COMPLETED
Chronic Hepatitis C; Hepatitis C (HCV); Hepatitis C Genotype 1a
AbbVie
2015-06 PHASE2
NCT01231685 COMPLETED
HIV; Hepatitis C; Liver Fibrosis
McGill University Health Centre/Research Institute of the McGill University Health Centre
2011-12 PHASE2
NCT01003990 COMPLETED
HIV
Bristol-Myers Squibb
2002-10 PHASE3
NCT02565888 COMPLETED
Hepatitis C; HIV
Radboud University Medical Center
2015-11 PHASE1
NCT02216422 COMPLETED
Chronic Hepatitis C Virus (HCV) Infection
AbbVie
2014-09 PHASE3
NCT02399345 COMPLETED
Chronic Hepatitis C Virus (HCV Infection Genotype 1)
AbbVie
2015-03 PHASE3
NCT01680536 COMPLETED
HIV
St Stephens Aids Trust
2012-11 PHASE4
NCT03019991 COMPLETED
Healthy
Ascletis Pharmaceuticals Co., Ltd.
2015-10 PHASE1
NCT01966822 COMPLETED
HIV-1 Infection
Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia
2014-01 PHASE3
NCT01910402 COMPLETED
Infection, Human Immunodeficiency Virus; HIV Infections
ViiV Healthcare
2013-08-22 PHASE3
NCT02534870 COMPLETED
Healthy Volunteer
AbbVie
2015-09 PHASE1
NCT01935830 COMPLETED
Healthy Volunteers
Washington University School of Medicine
2013-08 EARLY_PHASE1
NCT02289495 TERMINATED
Infection, Human Immunodeficiency Virus
GlaxoSmithKline
2014-11-18 PHASE1
NCT02219503 COMPLETED
Chronic Hepatitis C Infection; Compensated Cirrhosis
AbbVie
2014-09 PHASE3
NCT01852604 COMPLETED
Chronic Hepatitis C Virus
Merck Sharp & Dohme LLC
2013-03 PHASE2
NCT02023112 COMPLETED
Hepatitis C Virus
AbbVie
2014-01 PHASE3
NCT02322957 COMPLETED
Acute Herpes Zoster
ContraVir Pharmaceuticals, Inc.
2015-02 PHASE1
NCT00445146 COMPLETED
HIV Infections
Gilead Sciences
2007-02 PHASE2
NCT01679964 COMPLETED
HIV Infection; Adverse Drug Reaction; Quality of Life
Lin, Hsi-Hsun, M.D.
2012-07 PHASE4
NCT01749150 COMPLETED
Hepatitis C, Chronic
Hoffmann-La Roche
2013-04 PHASE2
NCT01351740 COMPLETED
HIV Infection
University of British Columbia
2011-07 PHASE4
NCT02023450 UNKNOWN
Pulmonary Arterial Hypertension
The Third Xiangya Hospital of Central South University
2013-12 EARLY_PHASE1
NCT01146873 COMPLETED
HIV/AIDS; HIV Infections
Columbia University
2010-07 PHASE3
NCT01825980 COMPLETED
Hepatitis C
Novartis Pharmaceuticals
2013-03 PHASE1; PHASE2
NCT01803074 COMPLETED
Infection, Human Immunodeficiency Virus; HIV Infections
ViiV Healthcare
2013-04-04 PHASE2
NCT02034838 COMPLETED
HIV Infection
Ottawa Hospital Research Institute
2014-01 PHASE1
NCT01854697 COMPLETED
Chronic Hepatitis C Infection
AbbVie
2013-03 PHASE3
NCT01691794 COMPLETED
HIV, Pediatric
Bristol-Myers Squibb
2012-11-30 PHASE4
NCT02203461 COMPLETED
Insulin Resistance
Technical University of Munich
2014-07 PHASE1
NCT01453933 UNKNOWN
HIV Infection; Endothelial Dysfunction
UMC Utrecht
2012-01 PHASE4
NCT01335698 COMPLETED
HIV
Bristol-Myers Squibb
2011-05-27 PHASE3
NCT01724086 COMPLETED
Chronic Hepatitis C
Janssen R&D Ireland
2012-10 PHASE2
NCT01935674 COMPLETED
HIV; Hypercholesterolaemia
Juan A. Arnaiz
2013-09 PHASE4
NCT01009437 COMPLETED
Breast Cancer
Masonic Cancer Center, University of Minnesota
2010-05-26 PHASE1
NCT01258439 COMPLETED
HIV; Cardiovascular Disease
St Vincent's Hospital, Sydney
2010-11 PHASE4
NCT02159352 COMPLETED
Hepatitis C
Bristol-Myers Squibb
2014-06 PHASE1
NCT01448707 COMPLETED
Human Immunodeficiency Virus (HIV) Infections; Acquired Immunodeficiency Syndrome (AIDS) Virus
Janssen-Cilag International NV
2012-03-15 PHASE3
NCT01533272 COMPLETED
HIV Infection
Hospital Clinic of Barcelona
2012-02 PHASE4
NCT01685203 COMPLETED
Hepatitis C, Chronic
AbbVie (prior sponsor, Abbott)
2012-08 PHASE2
NCT02063360 COMPLETED
Infection, Human Immunodeficiency Virus
ViiV Healthcare
2014-02-01 PHASE1
NCT01423812 COMPLETED
HIV
Ruth M. Rothstein CORE Center
2012-01 PHASE4
NCT01672983 COMPLETED
Chronic Hepatitis C Infection
AbbVie (prior sponsor, Abbott)
2012-07 PHASE2
NCT01343225 UNKNOWN
HIV
East Carolina University
2011-05 PHASE4
NCT01471821 COMPLETED
HIV Infection
Juan A. Arnaiz
2011-10 PHASE4
NCT02064842 COMPLETED
Healthy
Janssen R&D Ireland
2014-02 PHASE1
NCT01579019 WITHDRAWN
Hepatitis C, Chronic
Hoffmann-La Roche
2012-07 PHASE2
NCT01458977 COMPLETED
HIV; Dyslipidemia
Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia
2012-01 PHASE4
NCT01671982 COMPLETED
HIV
Institut de Recherche pour le Developpement
2012-08 PHASE1
NCT01704755 COMPLETED
Chronic Hepatitis C Infection; Compensated Cirrhosis
AbbVie (prior sponsor, Abbott)
2012-10 PHASE3
NCT01759875 COMPLETED
Healthy
University of California, San Francisco
2013-01 PHASE1
NCT01674725 COMPLETED
Chronic Hepatitis C Infection
AbbVie (prior sponsor, Abbott)
2012-08 PHASE3
NCT01172535 COMPLETED
HIV
National Institute of Allergy and Infectious Diseases (NIAID)
2010-11 PHASE2; PHASE3
NCT01185873 COMPLETED
Healthy Volunteer
Hoffmann-La Roche
2011-02 PHASE1
NCT01475838 COMPLETED
Acquired Immunodeficiency Syndrome; HIV Infections
Gilead Sciences
2011-11 PHASE3
NCT01715415 COMPLETED
Chronic Hepatitis C Infection
AbbVie (prior sponsor, Abbott)
2012-11 PHASE3
NCT01716585 COMPLETED
Chronic Hepatitis C Infection
AbbVie (prior sponsor, Abbott)
2012-11 PHASE3
NCT01483742 COMPLETED
Hepatitis C, Chronic
Hoffmann-La Roche
2012-04 PHASE2
NCT01332227 COMPLETED
HIV, Combination Therapy
Bristol-Myers Squibb
2011-10 PHASE4
NCT01516970 COMPLETED
Human Immunodeficiency Virus (HIV)
Janssen-Cilag G.m.b.H
2011-11-25 PHASE3
NCT01565889 COMPLETED
Hepatitis C; HIV
Gilead Sciences
2012-03 PHASE1; PHASE2
NCT01907724 COMPLETED
Hepatitis C, Chronic
Merck Sharp & Dohme LLC
2013-05 PHASE1
NCT00946595 COMPLETED
HIV Infections
French National Agency for Research on AIDS and Viral Hepatitis
2009-11 PHASE2; PHASE3
NCT01274780 COMPLETED
HIV-1
Juan A. Arnaiz
2011-05 PHASE4
NCT01118871 TERMINATED
HIV; HIV Infections
Imperial College London
2010-05 PHASE4
NCT01714154 COMPLETED
Healthy Volunteer
Hoffmann-La Roche
2012-11 PHASE1
NCT01449929 COMPLETED
Infection, Human Immunodeficiency Virus
ViiV Healthcare
2011-10-31 PHASE3
NCT01818856 COMPLETED
Hepatitis C, Chronic; HIV Infection
Hospitales Universitarios Virgen del Rocío
2012-12 PHASE1
NCT00877591 COMPLETED
Opioid Dependency; HIV Infections
University of California, San Francisco
2008-04 PHASE1
NCT01813552 COMPLETED
Chronic Hepatitis C Infection
Merck Sharp & Dohme LLC
2013-02 PHASE1
NCT01464827 COMPLETED
Chronic Hepatitis C; Hepatitis C (HCV); Hepatitis C Genotype 1
AbbVie (prior sponsor, Abbott)
2011-10 PHASE2
NCT01384734 COMPLETED
Infection, Human Immunodeficiency Virus
ViiV Healthcare
2011-07-26 PHASE2
NCT01583439 TERMINATED
HIV Infections
Harvard School of Public Health (HSPH)
2012-09
NCT01656109 COMPLETED
HIV
The HIV Netherlands Australia Thailand Research Collaboration
2011-07 PHASE2
NCT01620944 TERMINATED
HIV
Bristol-Myers Squibb
2012-07-31 PHASE3
NCT00978068 COMPLETED
Malaria; HIV Infections
University of California, San Francisco
2009-09 PHASE3
NCT01331850 COMPLETED
Hepatitis C, Chronic
Hoffmann-La Roche
2011-05 PHASE2
NCT00540137 COMPLETED
HIV Infections
Imperial College London
2007-07 PHASE4
NCT01105611 UNKNOWN
HIV Infections; Hepatitis C
St. James's Hospital, Ireland
2010-08 PHASE4
NCT01220947 COMPLETED
Hepatitis C, Chronic
Hoffmann-La Roche
2010-11 PHASE2
NCT01189695 COMPLETED
HIV; AIDS; Lopinavir; Treatment Failure
Bamrasnaradura Infectious Diseases Institute
2010-12 PHASE4
NCT01654211 COMPLETED
Healthy Volunteer
Hoffmann-La Roche
2012-07 PHASE1
NCT01099579 COMPLETED
HIV Infections
Bristol-Myers Squibb
2010-10-13 PHASE3
NCT01278134 COMPLETED
Hepatitis C, Chronic
Hoffmann-La Roche
2011-02 PHASE2
NCT01199939 COMPLETED
Human Immunodeficiency Virus (HIV)
Tibotec, Inc
2010-05 PHASE2
NCT00994344 COMPLETED
HIV Infections
Germans Trias i Pujol Hospital
2009-10 PHASE4
NCT01660477 COMPLETED
Pharmacokinetics of Isavuconazole; Pharmacokinetics of Lopinavir/Ritonavir; Healthy Volunteers
Astellas Pharma Global Development, Inc.
2012-06 PHASE1
NCT01513122 COMPLETED
HIV
Kirby Institute
2010-02 PHASE4
NCT00102960 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
2005-07 PHASE3
NCT00608569 COMPLETED
HIV Infections
Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
2009-03
NCT00605098 COMPLETED
HIV Infections; Pregnancy
Oswaldo Cruz Foundation
2008-02 PHASE4
NCT00865007 COMPLETED
HIV Infection; Lipodystrophy; HIV Infections
Fundacion SEIMC-GESIDA
2008-12 PHASE4
NCT01102972 COMPLETED
Infection, Human Immunodeficiency Virus
ViiV Healthcare
2010-04 PHASE4
NCT01602822 TERMINATED
HIV
Kenneth H. Mayer, MD
2012-02 PHASE4
NCT01237444 COMPLETED
HIV Infection
Pedro Cahn
2010-12 PHASE3
NCT01475227 COMPLETED
HIV Infection
St Stephens Aids Trust
2011-12 PHASE4
NCT01294761 COMPLETED
HIV Infections
National Center for Global Health and Medicine, Japan
2011-02
NCT01348763 COMPLETED
HIV
Imperial College London
2011-10 PHASE1
NCT01514968 COMPLETED
Healthy Volunteer
Hoffmann-La Roche
2011-12 PHASE1
NCT01166477 COMPLETED
HIV Infection
Sociedad Andaluza de Enfermedades Infecciosas
2010-01 PHASE4
NCT00802334 COMPLETED
HIV
The HIV Netherlands Australia Thailand Research Collaboration
2008-01 PHASE2
NCT01194856 TERMINATED
HIV Infection; Mitochondrial Dysfunction
The Cleveland Clinic
2010-10 PHASE4
NCT01458054 COMPLETED
Hepatitis C
GlaxoSmithKline
2011-09-27 PHASE1
NCT01398293 COMPLETED
Healthy Volunteer
Hoffmann-La Roche
2011-08 PHASE1
NCT01108510 COMPLETED
HIV; HIV Infections
Gilead Sciences
2010-04 PHASE3
NCT01088516 COMPLETED
HIV
University of Zambia
2008-12 PHASE4
NCT01772940 COMPLETED
HIV-1 Infection
Centre Hospitalier Universitaire Saint Pierre
2008-12 PHASE4
NCT00234091 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
2006-04 PHASE3
NCT01392755 COMPLETED
Healthy Volunteer
Hoffmann-La Roche
2011-07 PHASE1
NCT01106586 COMPLETED
HIV; HIV Infections
Gilead Sciences
2010-04 PHASE3
NCT01418274 COMPLETED
Healthy Volunteer
Hoffmann-La Roche
2011-08 PHASE1
NCT01389544 COMPLETED
Healthy Volunteer
Hoffmann-La Roche
2011-06 PHASE1
NCT00849160 COMPLETED
HIV-1 Infection; HIV Infections
Centre de Recherches et d'Etude sur la Pathologie Tropicale et le Sida
2009-05 PHASE3
NCT01422369 COMPLETED
Healthy
Kowa Research Institute, Inc.
2011-04 PHASE4
NCT01074008 COMPLETED
Hepatitis C; HCV; Chronic Hepatitis C Infection; Hepatitis C Genotype 1
AbbVie (prior sponsor, Abbott)
2010-03 PHASE2
NCT01231451 WITHDRAWN
HIV Infection
St Stephens Aids Trust
2010-12 PHASE1
NCT01165645 WITHDRAWN
Hodgkin Lymphoma; Stage I Adult Hodgkin Lymphoma; Stage II Adult Hodgkin Lymphoma; Stage III Adult Hodgkin Lymphoma; Stage IV Adult Hodgkin Lymphoma
Mayo Clinic
2010-11
NCT00089583 COMPLETED
Infection, Human Immunodeficiency Virus I
ViiV Healthcare
2004-07 PHASE2
NCT00335322 COMPLETED
Human Immunodeficiency Virus (HIV)
Kirby Institute
2007-02 PHASE4
NCT00724711 COMPLETED
HIV Infection
Gilead Sciences
2008-07 PHASE4
NCT01227590 COMPLETED
Drug Interactions; Human Immunodeficiency Virus
University of California, San Francisco
2010-02 PHASE1
NCT00708162 COMPLETED
HIV Infection
Gilead Sciences
2008-07 PHASE3
NCT00307151 COMPLETED
HIV Infections
International Maternal Pediatric Adolescent AIDS Clinical Trials Group
2005-12 PHASE2
NCT00869960 COMPLETED
Healthy
University of Alabama at Birmingham
2009-03 PHASE4
NCT01057433 COMPLETED
Healthy Volunteers
Kowa Research Institute, Inc.
2010-01 PHASE4
NCT00775606 TERMINATED
Acquired Immune Deficiency Syndrome
Rush University Medical Center
2008-10 PHASE4
NCT01010399 COMPLETED
Hypertriglyceridemia; HIV Infection
Felizarta, Franco, M.D.
2009-09 PHASE4
NCT00266058 COMPLETED
HIV Infections; Malaria
University of California, San Francisco
2005-12 PHASE1
NCT01209065 COMPLETED
Infections, Human Immunodeficiency Virus and Herpesviridae
ViiV Healthcare
2010-09 PHASE1
NCT01140412 TERMINATED
Healthy
ViiV Healthcare
2010-07 PHASE1
NCT00640887 COMPLETED
HIV Infections; Tuberculosis
French National Agency for Research on AIDS and Viral Hepatitis
2009-02 PHASE2
NCT00296504 COMPLETED
Infection, Human Immunodeficiency Virus
ViiV Healthcare
2001-11 PHASE3
NCT01156389 COMPLETED
Malaria
Medicines for Malaria Venture
2010-07 PHASE1
NCT00919854 COMPLETED
Human Immunodeficiency Virus 1
Tibotec Pharmaceuticals, Ireland
2009-09 PHASE2
NCT01164488 COMPLETED
Healthy Volunteer
Hoffmann-La Roche
2010-07 PHASE1
NCT00827112 COMPLETED
Human Immunodeficiency Virus-1
ViiV Healthcare
2009-03 PHASE2
NCT00437684 UNKNOWN
HIV Infections; Hepatitis C
IRCCS San Raffaele
2007-02 PHASE3
NCT00437476 UNKNOWN
HIV Infections; Hepatitis C
IRCCS San Raffaele
2007-02 PHASE3
NCT00765154 TERMINATED
HIV
St Stephens Aids Trust
2008-10 PHASE4
NCT00440947 COMPLETED
Infection, Human Immunodeficiency Virus I; HIV Infection
ViiV Healthcare
2007-03 PHASE3
NCT01009814 COMPLETED
HIV Infections
ViiV Healthcare
2009-11-23 PHASE2
NCT00076999 COMPLETED
HIV Infections
Boehringer Ingelheim
2003-11 PHASE1
NCT01073761 COMPLETED
HIV; HIV Infections
St Stephens Aids Trust
2010-04 PHASE1
NCT00421551 COMPLETED
HIV Infections
French National Agency for Research on AIDS and Viral Hepatitis
2007-03 PHASE3
NCT00885482 COMPLETED
HIV Infections
Catholic University of the Sacred Heart
2009-05 PHASE4
NCT01091649 COMPLETED
Healthy
Abbott
2010-02 PHASE1
NCT01046890 COMPLETED
HIV Infections
Germans Trias i Pujol Hospital
2010-01 PHASE4
NCT00100646 COMPLETED
HIV Infections
The Wistar Institute
2007-03
NCT00623597 COMPLETED
HIV Infections
Hoffmann-La Roche
2008-06 PHASE2
NCT00552240 COMPLETED
HIV Infections
Boehringer Ingelheim
2007-09 PHASE4
NCT00632970 TERMINATED
HIV Infections
George Washington University
2008-02 PHASE4
NCT00543101 COMPLETED
HIV Infections
Community Research Initiative of New England
2007-10 PHASE4
NCT00768989 TERMINATED
HIV
Bristol-Myers Squibb
2008-11 PHASE2
NCT01445223 COMPLETED
HIV
Göteborg University
2004-04 PHASE4
NCT00892437 COMPLETED
HIV-1 Infection
Gilead Sciences
2009-05 PHASE2
NCT00159224 COMPLETED
HIV Infections
Fundación Huésped
2005-04 PHASE4
NCT01049685 UNKNOWN
HIV Infections
UPECLIN HC FM Botucatu Unesp
2006-08 PHASE4
NCT00307502 COMPLETED
HIV Infections
Germans Trias i Pujol Hospital
2005-01 PHASE1
NCT00118898 COMPLETED
HIV Infections
Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
2005-09 PHASE3
NCT00711009 COMPLETED
Human Immunodeficiency Virus Infection
Abbott
2008-07 PHASE3
NCT00630734 COMPLETED
HIV Infections; Hyperlipidemia
University of Colorado, Denver
2008-02 PHASE4
NCT00772902 COMPLETED
HIV-1
Gilead Sciences
2008-10 PHASE4
NCT00885664 COMPLETED
HIV Infections
University of Cincinnati
2005-10 PHASE4
NCT00838162 COMPLETED
Human Immunodeficiency Virus Type 1
Tibotec Pharmaceuticals, Ireland
2009-06 PHASE2
NCT00385645 COMPLETED
HIV Infections
Hospital Clinic of Barcelona
2006-05 PHASE4
NCT00524368 COMPLETED
Human Immunodeficiency Virus - Type 1
Tibotec Pharmaceuticals, Ireland
2007-10 PHASE3
NCT00850044 COMPLETED
HCV Infection
AbbVie
2009-02 PHASE1
NCT00909311 COMPLETED
HCV Infection
Abbott
2009-05 PHASE1
NCT00817765 COMPLETED
HIV Infection; Fungal Infection
Radboud University Medical Center
2009-01 PHASE1
NCT00611039 COMPLETED
HIV Infections
Germans Trias i Pujol Hospital
2008-02 PHASE4
NCT00797745 COMPLETED
Hepatitis C, Chronic
Merck Sharp & Dohme LLC
2008-11 PHASE2
NCT00883935 COMPLETED
Healthy Volunteer
GlaxoSmithKline
2009-04 PHASE1
NCT00867152 COMPLETED
Healthy Volunteer
ViiV Healthcare
2009-04 PHASE1
NCT00810108 COMPLETED
HIV/AIDS Treatment; HIV Infections
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
2006-06 PHASE4
NCT00260078 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
2006-02 PHASE1; PHASE2
NCT00833378 COMPLETED
Hepatitis C
GlaxoSmithKline
2009-01-19 PHASE1
NCT00270296 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
2006-06 PHASE2
NCT00458302 COMPLETED
HIV Infections; AIDS Virus; Human Immunodeficiency Virus; Acquired Immunodeficiency Syndrome Virus
Janssen-Cilag International NV
2007-06 PHASE3
NCT00438152 COMPLETED
HIV Infections
Royal Free Hampstead NHS Trust
2006-09 PHASE4
NCT00887120 COMPLETED
HIV Infections
The HIV Netherlands Australia Thailand Research Collaboration
2007-04 PHASE2
NCT00255840 COMPLETED
HIV Infections
CIPRA SA
2006-07
NCT00326716 COMPLETED
HIV Infection
Bristol-Myers Squibb
2006-06 PHASE1
NCT00966160 COMPLETED
Acquired Immunodeficiency Syndrome; HIV Infections
University of Cologne
1999-01 PHASE3
NCT00744887 COMPLETED
HIV; AIDS
Tibotec Pharmaceuticals, Ireland
2008-08 PHASE1
NCT00413153 COMPLETED
HIV Infections
Massachusetts General Hospital
2006-05
NCT00661349 TERMINATED
HIV Infections
Germans Trias i Pujol Hospital
2008-02 PHASE4
NCT00767117 COMPLETED
HIV
Tibotec Pharmaceuticals, Ireland
2008-09 PHASE1
NCT00774735 COMPLETED
Healthy Subjects; Infection, Human Immunodeficiency Virus
GlaxoSmithKline
2008-10 PHASE1
NCT00764465 COMPLETED
Healthy
Garden State Infectious Disease Associates, PA
2008-10 PHASE2
NCT00528060 COMPLETED
HIV Infections
French National Agency for Research on AIDS and Viral Hepatitis
2008-01 PHASE2
NCT00717067 COMPLETED
Human Immunodeficiency Virus (HIV) Infection
ViiV Healthcare
2008-07 PHASE4
NCT00770042 COMPLETED
Erectile Dysfunction
VIVUS LLC
2008-10 PHASE1
NCT02259855 COMPLETED
Hepatic Insufficiency
Boehringer Ingelheim
2006-01-01 PHASE1
NCT00440271 TERMINATED
HIV Infections
Boehringer Ingelheim
2007-02 PHASE3
NCT00775125 COMPLETED
Hepatitis C; Telaprevir; HIV
Tibotec BVBA
2008-06 PHASE1
NCT00109590 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
2006-06 PHASE2
NCT00144170 COMPLETED
HIV Infections
Boehringer Ingelheim
2003-02 PHASE3
NCT00447902 TERMINATED
HIV Infections
Boehringer Ingelheim
2007-03 PHASE3
NCT00517192 TERMINATED
HIV Infections
Boehringer Ingelheim
2007-09 PHASE3
NCT00571961 COMPLETED
HIV Infections
Yale University
2007-01
NCT00531999 COMPLETED
HIV Infections
St Stephens Aids Trust
2007-10 PHASE1
NCT01081158 COMPLETED
Hepatitis C, Chronic
Merck Sharp & Dohme LLC
2007-07 PHASE1
NCT00646776 COMPLETED
Antivirals/HIV
Bristol-Myers Squibb
2008-04 PHASE1
NCT00450580 COMPLETED
Infection, Human Immunodeficiency Virus I; HIV-1 Infection
ViiV Healthcare
2007-03 PHASE3
NCT00474201 COMPLETED
Healthy Volunteers
National Institutes of Health Clinical Center (CC)
2007-05
NCT02251795 COMPLETED
Healthy
Boehringer Ingelheim
2007-08 PHASE1
NCT02183441 COMPLETED
Healthy
Boehringer Ingelheim
2008-04 PHASE1
NCT02244190 COMPLETED
Healthy
Boehringer Ingelheim
2008-04 PHASE1
NCT00337467 COMPLETED
Human Immunodeficiency Virus (HIV) Infections
Bristol-Myers Squibb
2006-06 PHASE3
NCT00146328 COMPLETED
HIV Infections
Boehringer Ingelheim
2001-04 PHASE2; PHASE3
NCT00379405 COMPLETED
HIV Infections
Germans Trias i Pujol Hospital
2006-06 PHASE4
NCT00534352 COMPLETED
HIV-1 Infection
Tibotec, Inc
2008-01 PHASE2
NCT00622206 COMPLETED
HIV Infections
The HIV Netherlands Australia Thailand Research Collaboration
2008-01 PHASE1; PHASE2
NCT00460382 COMPLETED
HIV Infections
French National Agency for Research on AIDS and Viral Hepatitis
2007-05 PHASE2
NCT00355719 COMPLETED
HIV Infections
Germans Trias i Pujol Hospital
2007-01 PHASE4
NCT00143689 COMPLETED
HIV; Mitochondrial Toxicity
University of British Columbia
2002-04 PHASE4
NCT00084149 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
2004-02 PHASE2
NCT01891851 COMPLETED
Healthy
Tibotec Pharmaceuticals, Ireland
2007-10 PHASE1
NCT00140751 COMPLETED
HIV Infections
Institut de Médecine et d'Epidémiologie Appliquée - Fondation Internationale Léon M'Ba
2005-10 PHASE3
NCT00234975 COMPLETED
HIV Infection
AbbVie (prior sponsor, Abbott)
2002-10 PHASE4
NCT00145561 COMPLETED
HIV Infections
Radboud University Medical Center
2005-08 PHASE1; PHASE2
NCT00051831 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
2003-10
NCT00335270 COMPLETED
HIV
Duke University
2006-03 PHASE4
NCT00420355 TERMINATED
HIV Infection
University of Oklahoma
2007-04 PHASE4
NCT02229760 TERMINATED
HIV Infections
Boehringer Ingelheim
2006-08 PHASE1; PHASE2
NCT00105079 COMPLETED
HIV Infections
Hoffmann-La Roche
2005-04 PHASE3
NCT00135356 COMPLETED
HIV-Associated Lipodystrophy Syndrome
Bristol-Myers Squibb
2005-07 PHASE4
NCT02226978 COMPLETED
Healthy
Boehringer Ingelheim
2007-02 PHASE1
NCT00160329 COMPLETED
Hyperlipidemia; HIV Infections
Stanford University
2004-01 PHASE3
NCT00312754 TERMINATED
HIV Infections
Bristol-Myers Squibb
2005-06 PHASE4
NCT00477126 COMPLETED
Healthy
The HIV Netherlands Australia Thailand Research Collaboration
2007-01 PHASE1
NCT00234923 COMPLETED
HIV Infection
Abbott
2003-08 PHASE3
NCT00148759 COMPLETED
HIV Infections
Emory University
2005-06 PHASE4
NCT02253940 COMPLETED
Healthy
Boehringer Ingelheim
2006-10 PHASE1
NCT00393328 COMPLETED
HIV Infections
Bristol-Myers Squibb
2006-11 PHASE1
NCT00648999 COMPLETED
Human Immunodeficiency Virus
AbbVie (prior sponsor, Abbott)
2003-11 PHASE4
NCT00144105 TERMINATED
HIV Infections
Boehringer Ingelheim
2004-02 PHASE2
NCT00362726 COMPLETED
HIV Infections
Bristol-Myers Squibb
2006-09 PHASE1
NCT00720590 COMPLETED
Endothelial Dysfunction
Indiana University
2003-11
NCT00357188 COMPLETED
HIV Infections; Protease Inhibitor
Bristol-Myers Squibb
2006-07 PHASE1
NCT00352066 COMPLETED
HIV Infection
Avexa
2006-07 PHASE1
NCT00162149 COMPLETED
HIV Infections
Bristol-Myers Squibb
2005-10 PHASE1
NCT02243553 COMPLETED
Healthy
Boehringer Ingelheim
2006-01 PHASE1
NCT00365339 COMPLETED
HIV Infections
Bristol-Myers Squibb
2006-04 PHASE1
NCT00120393 COMPLETED
HIV Infections
Bristol-Myers Squibb
2004-01 PHASE3
NCT00144287 COMPLETED
HIV Infections
Boehringer Ingelheim
2004-05 PHASE3
NCT02253862 COMPLETED
Healthy
Boehringer Ingelheim
2005-12 PHASE1
NCT02248883 COMPLETED
Healthy
Boehringer Ingelheim
2005-12 PHASE1
NCT00135395 COMPLETED
HIV Infections
Bristol-Myers Squibb
2004-05 PHASE3
NCT02253875 COMPLETED
Healthy
Boehringer Ingelheim
2005-11 PHASE1
NCT00197197 TERMINATED
HIV Infection
GlaxoSmithKline
2005-07 PHASE3
NCT02259868 COMPLETED
Healthy
Boehringer Ingelheim
2005-06 PHASE1
NCT02256826 COMPLETED
Healthy
Boehringer Ingelheim
2005-04 PHASE1
NCT02257021 COMPLETED
Healthy
Boehringer Ingelheim
2005-02 PHASE1
NCT00004578 COMPLETED
HIV Infections
Abbott
1997-11 PHASE1; PHASE2
NCT00014937 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
NCT02253914 COMPLETED
Healthy
Boehringer Ingelheim
2004-02 PHASE1
NCT02253953 COMPLETED
Healthy
Boehringer Ingelheim
2002-11 PHASE1
NCT02251171 COMPLETED
Healthy
Boehringer Ingelheim
2003-08 PHASE1
NCT00028301 COMPLETED
HIV Infections
Bristol-Myers Squibb
2001-02 PHASE3
NCT02195466 COMPLETED
Healthy
Boehringer Ingelheim
2003-06 PHASE1
NCT00046033 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT02245438 TERMINATED
Healthy
Boehringer Ingelheim
2002-05 PHASE1
NCT02251873 COMPLETED
Healthy
Boehringer Ingelheim
2001-09 PHASE1
NCT02239835 TERMINATED
HIV Infections
Boehringer Ingelheim
1999-12 PHASE2
NCT02238314 COMPLETED
HIV Infections
Boehringer Ingelheim
1999-01 PHASE2
NCT02251132 COMPLETED
Healthy
Boehringer Ingelheim
2000-10 PHASE1
NCT02249130 COMPLETED
HIV Infections
Boehringer Ingelheim
1999-03 PHASE2
NCT00116636 COMPLETED
HIV Infections
Therapeutic Concepts
2005-06 PHASE2
NCT00002451 UNKNOWN
HIV Infections
Merck Sharp & Dohme LLC
PHASE2
NCT00025727 UNKNOWN
HIV Infections
GlaxoSmithKline
2001-05 PHASE3
NCT00063804 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00044837 TERMINATED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00006339 WITHDRAWN
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT00102986 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
2005-10
NCT00001688 COMPLETED
HIV Infection
National Cancer Institute (NCI)
1998-01 PHASE2
NCT00122577 TERMINATED
HIV Infections
French National Agency for Research on AIDS and Viral Hepatitis
2002-03 PHASE2
NCT01323257 COMPLETED
Hepatitis C Virus
Tibotec Pharmaceuticals, Ireland
2011-03 PHASE1
NCT00005118 UNKNOWN
HIV Infections
Merck Sharp & Dohme LLC
PHASE2
NCT00148785 COMPLETED
HIV Infections
Emory University
2005-07 PHASE4
NCT00028366 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00002378 COMPLETED
HIV Infections
Hoffmann-La Roche
PHASE3
NCT00012519 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1; PHASE2
NCT00084058 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1; PHASE2
NCT00017992 UNKNOWN
HIV Infections
Triangle Pharmaceuticals
PHASE2
NCT00002178 COMPLETED
HIV Infections
Hoffmann-La Roche
PHASE3
NCT00006578 WITHDRAWN
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00038519 COMPLETED
HIV Infections
Abbott
2001-04 PHASE2; PHASE3
NCT00002241 UNKNOWN
HIV Infections
Merck Sharp & Dohme LLC
PHASE2
NCT00481182 COMPLETED
Healthy Subjects
GlaxoSmithKline
2005-02 PHASE1
NCT00000924 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT00004582 COMPLETED
HIV Infections
ViRx
PHASE2
NCT00038636 COMPLETED
HIV Infections
Abbott
2000-09 PHASE3
NCT00002201 COMPLETED
HIV Infections
Abbott
NCT00039975 COMPLETED
HIV Infections; Cardiovascular Diseases; Hypertension
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00036452 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT00000822 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00000919 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00006144 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
2000-10 PHASE2
NCT00085943 COMPLETED
HIV Infection; Infection, Human Immunodeficiency Virus
GlaxoSmithKline
2004-05 PHASE3
NCT00000952 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00002447 COMPLETED
HIV Infections
Hoffmann-La Roche
1999-10 PHASE3
NCT00023218 WITHDRAWN
HIV Infections; Hepatitis C
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00002448 COMPLETED
HIV Infections
Hoffmann-La Roche
1999-10 PHASE3
NCT00121017 WITHDRAWN
HIV Infection; Hepatitis C
Abbott
PHASE2
NCT00001108 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00001091 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00002361 COMPLETED
HIV Infections
Merck Sharp & Dohme LLC
PHASE2
NCT01368783 UNKNOWN
Atazanavir
Asan Medical Center
2011-06 PHASE1
NCT00000940 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
1999-05 PHASE2
NCT00000891 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT00000920 COMPLETED
HIV Infections; Pregnancy
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00076414 COMPLETED
Healthy
National Institutes of Health Clinical Center (CC)
2004-01 PHASE1
NCT00001087 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT00001083 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT00004583 COMPLETED
HIV Infections
Abbott
1999-03 PHASE3
NCT00001766 COMPLETED
HIV Infection
National Institute of Allergy and Infectious Diseases (NIAID)
1998-08 PHASE1
NCT00038532 COMPLETED
HIV Infections
Abbott
2001-04 PHASE2
NCT00075907 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
2004-07 PHASE3
NCT00114933 COMPLETED
HIV Infection
Arribas, Jose R., M.D.
2005-01 PHASE4
NCT00000941 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00002223 COMPLETED
HIV Infections
Abbott
NCT00028314 COMPLETED
HIV Infections; Lipodystrophy; Wasting Disease
National Institute of Allergy and Infectious Diseases (NIAID)
2002-03
NCT00000906 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00080522 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
2005-02
NCT00002374 COMPLETED
HIV Infections
Hoffmann-La Roche
PHASE3
NCT00162643 UNKNOWN
Acquired Immunodeficiency Syndrome
Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
2004-12 PHASE4

(data from https://clinicaltrials.gov, updated on 2026-06-10)

Check the Ritonavir product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Compliance for Clinical Use

Mechanism and Biochemical Profile

Ritonavir potently binds to and inhibits HIV protease as well as hepatic cytochrome P450 3A4 (CYP3A4), thereby blocking viral polyprotein processing and preventing the metabolic degradation of co-administered drugs. This dual inhibition prevents the assembly of mature infectious virions while enhancing the systemic exposure of companion antivirals, demonstrating critical clinical utility in combination therapies for HIV infections and COVID-19.

Appendix RUO and cGMP Quality Standards

Quality Dimension RUO (Research Use Only) cGMP (Current Good Manufacturing Practice)
Clinical Applicability Prohibited in human clinical trials or medical diagnostics. Mandatory for human clinical trials (Phase I–III) and therapies.
Regulatory Status Non-regulated grade; exempt from drug manufacturing laws. Legally enforced by health authorities (e.g., FDA, EMA, NMPA).
Facility Environment Unclassified analytical or research laboratories. Validated Cleanrooms (ISO Class 5–8) with continuous monitoring.
Quality Control Basic purity and activity testing. Rigorous safety release testing (Sterility, Endotoxin, Mycoplasma).
Process Validation Basic equipment calibration; no process validation required. Full qualification (IQ/OQ/PQ) and complete batch records.
Quality Assurance Vendor self-declared without required formal QMS. Mandatory QA/QC unit, Change Control, CAPA, and vendor audits.
Regulatory Impact High risk of IND rejection if used as a critical raw material. Required for IND/NDA filings, supported by Drug Master Files (DMF).

Footnotes

Regulatory Note: Governed by FDA (21 CFR Parts 210/211/312), EMA (EudraLex Vol 4), ICH Guidelines (E6/Q7/Q9/Q10), and compendial standards (USP <71>/<85>/<1043>).

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Note: Technical data last updated: Sep 1, 2026.