CAS No. 6119-47-7
Batch:
Purity:99.98
Chemical Structure
Check the
Quinine HCl Dihydrate
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | (R)-[(2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol;dihydrate;hydrochloride | |
|---|---|---|
| CAS Number | 6119-47-7 | |
| Molecular Formula |
C20H24N2O2.HCl.2H2O |
|
| Molecular Weight (MW) | 396.91 | |
| SMILES | COC1=CC2=C(C=CN=C2C=C1)C(C3CC4CCN3CC4C=C)O.O.O.Cl | |
| InChIKey | MPQKYZPYCSTMEI-FLZPLBAKSA-N |
Quinine HCl Dihydrate is a naturally occurring cinchona alkaloid that acts as a potassium (K+) channel blocker and antimalarial agent. By inhibiting potassium conductance and interfering with plasmodial heme detoxification, it disrupts cellular ion homeostasis and inhibits parasite proliferation. It also exhibits antipyretic, analgesic, and anti-inflammatory activities, suppressing fever and inflammatory signaling pathways in cellular responses.
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Concentration
Volume
Mass
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|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
79 mg/mL
(199.03 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 79 mg/mL |
| Water | 43 mg/mL |
| DMSO |
79 mg/mL
(199.03 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 79 mg/mL |
| Water | 43 mg/mL |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
- Quinine HCl Dihydrate Clinical Trials
- Quinine HCl Dihydrate Solubility in DMSO
- Quinine HCl Dihydrate Stock Solution
- Quinine HCl Dihydrate Storage
- Quinine HCl Dihydrate Stability
- Quinine HCl Dihydrate Molecular Weight
- Quinine HCl Dihydrate SMILES
- Quinine HCl Dihydrate Chemical Structure (2D and 3D)
- Quinine HCl Dihydrate SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.