CAS No. 191217-81-9

Batch: Purity:99.96
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Pramipexole 2HCl Monohydrate Chemical Structure
Chemical Structure
Check the Pramipexole 2HCl Monohydrate product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 191217-81-9
Molecular Formula

C10H17N3S.2HCl.H2O
Molecular Weight (MW) 302.26
SMILES CCCNC1CCC2=C(C1)SC(=N2)N.O.Cl.Cl

Ordering Information

Biological Activity

Pramipexole 2HCl Monohydrate is a non-ergoline dopamine receptor agonist that selectively targets the dopamine D3 receptor, D2L receptor, D2S receptor, and D4 receptor. By activating presynaptic and postsynaptic dopamine D2 and D3 receptors, it modulates dopaminergic signaling pathways to inhibit neuronal firing and regulate motor function. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 60 mg/mL (198.5 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 60 mg/mL
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.