CAS No. 1400-61-9

Nystatin Chemical Structure
Chemical Structure
Check the Nystatin product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name (1S,15S,16R,17R,18S,19E,21E,25E,27E,29E,31E)-33-[(2S,3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy-1,3,4,7,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,25,27,29,31-hexaene-36-carboxylic acid
CAS Number 1400-61-9
Molecular Formula

C47H75NO17

Molecular Weight (MW) 926.09
SMILES CC1C=CC=CCCC=CC=CC=CC=CC(CC2C(C(CC(O2)(CC(C(CCC(CC(CC(CC(=O)OC(C(C1OC3CC(C(C(O3)C)O)O)C)C)O)O)O)O)O)O)O)C(=O)O)OC4C(C(C(C(O4)C)O)N)O
InChIKey VQOXZBDYSJBXMA-RKEBNKJGSA-N

Ordering Information

Biological Activity

Nystatin is a polyene antifungal compound that targets membrane ergosterol in susceptible molds and yeasts, including Candida species. By binding directly to ergosterol within fungal cell membranes, it disrupts membrane integrity and increases cellular permeability, leading to leakage of essential intracellular contents and fungal cell death. This membrane disruption suppresses fungal proliferation and viable cell growth. [1]

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Note: Technical data last updated: Sep 1, 2026.