CAS No. 24280-93-1

Batch: Purity:99.95
Mycophenolic Acid (Mycophenolate, MPA) Chemical Structure
Chemical Structure
Check the Mycophenolic Acid (Mycophenolate, MPA) product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-2-benzofuran-5-yl)-4-methylhex-4-enoic acid
CAS Number 24280-93-1
Molecular Formula

C17H20O6

Molecular Weight (MW) 320.34
SMILES CC1=C2COC(=O)C2=C(C(=C1OC)CC=C(C)CCC(=O)O)O
InChIKey HPNSFSBZBAHARI-RUDMXATFSA-N

Ordering Information

Biological Activity

Mycophenolic acid is an immunosuppressive agent that acts as a potent inhibitor of inosine monophosphate dehydrogenase (IMPDH). By inhibiting IMPDH, it disrupts the de novo pathway of purine nucleotide synthesis and depletes intracellular guanine nucleotides. This depletion selectively suppresses the proliferation of T and B lymphocytes, leading to marked anti-proliferative and immunosuppressive effects in immune cell responses. [1][2]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 64 mg/mL (199.78 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 32 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.