Numerous clinical trials spanning Phases 1 through 4 evaluate methylprednisolone across diverse medical indications, including steroid-refractory graft-versus-host disease, hemophilia A, kidney transplant rejection, coronavirus infection, IgA glomerulonephritis, and neurosurgical postoperative pain. Sponsored by both academic institutions and biopharmaceutical companies, these protocols reflect varied recruitment statuses, including recruiting, active not recruiting, completed, and terminated. Overall, these efforts reflect extensive research into methylprednisolone for managing inflammatory and immune-mediated disorders.
| NCT Number | Recruitment | Conditions | Sponsor/Collaborators | Start Date | Phases |
|---|---|---|---|---|---|
| NCT07072585 | NOT_YET_RECRUITING | Stage II T Lymphoblastic Leukemia/Lymphoma; Stage III T Lymphoblastic Leukemia/Lymphoma; Stage IV T Lymphoblastic Leukemia/Lymphoma; T Acute Lymphoblastic Leukemia; T Lymphoblastic Lymphoma |
Children's Oncology Group |
2026-08-28 | PHASE2; PHASE3 |
| NCT07478003 | RECRUITING | STEMI - ST Elevation Myocardial Infarction |
Thomas Engstrom |
2026-04-20 | PHASE3 |
| NCT07258771 | RECRUITING | Ulcerative Colitis Acute |
Berinstein, Jeffrey |
2026-01-16 | PHASE4 |
| NCT06970743 | ACTIVE_NOT_RECRUITING | Chronic Lymphocytic Leukemia; Small Lymphocytic Lymphoma |
BeOne Medicines |
2025-05-29 | PHASE3 |
| NCT07703098 | NOT_YET_RECRUITING | Adrenal Insufficiency |
University Medical Centre Ljubljana |
2026-09-01 | PHASE4 |
| NCT07412470 | RECRUITING | Kidney Transplant Rejection |
Sanofi |
2026-03-13 | PHASE2; PHASE3 |
| NCT01624805 | RECRUITING | Aplastic Anemia; de Novo Myelodysplastic Syndrome; Myelodysplastic Syndrome; Previously Treated Myelodysplastic Syndrome |
M.D. Anderson Cancer Center |
2012-06-25 | PHASE2 |
| NCT07507643 | RECRUITING | Hepatectomy |
Memorial Sloan Kettering Cancer Center |
2026-03-27 | PHASE3 |
| NCT02784210 | RECRUITING | Multiple Sclerosis |
National Institute of Neurological Disorders and Stroke (NINDS) |
2016-10-05 | PHASE2 |
| NCT07352865 | NOT_YET_RECRUITING | Psittacosis |
Qingyuan Zhan |
2026-01-15 | PHASE3 |
| NCT03219359 | RECRUITING | Crohn Disease |
Aaron Etra |
2018-02-22 | PHASE2 |
| NCT07357935 | NOT_YET_RECRUITING | Acute Respiratory Failure; Community-Acquired Pneumonia |
Qingyuan Zhan |
2026-02-01 | PHASE1; PHASE2 |
| NCT07455396 | RECRUITING | Asthma (Diagnosis) |
Johns Hopkins All Children's Hospital |
2026-08-01 | PHASE2 |
| NCT07542288 | NOT_YET_RECRUITING | Brain Metastases From Solid Tumors |
The Second Affiliated Hospital of Hainan Medical University |
2026-04-15 | PHASE2; PHASE3 |
| NCT07265258 | RECRUITING | Thyroid Eye Disease |
Innovent Biologics (Suzhou) Co. Ltd. |
2026-07-30 | PHASE4 |
| NCT07371572 | RECRUITING | Hand Osteoarthritis |
Sint Maartenskliniek |
2025-10-28 | PHASE3 |
| NCT07525466 | RECRUITING | Extranodal NK T Cell Lymphoma; Hemophagocytic Lymphohistiocytosis (HLH) |
Beijing Tongren Hospital |
2026-04-01 | PHASE1; PHASE2 |
| NCT07804199 | NOT_YET_RECRUITING | Knee Osteoarthritis |
VA Office of Research and Development |
2026-10-01 | |
| NCT07650396 | RECRUITING | Achilles Tendinopathy (AT) |
Erasmus Medical Center |
2026-06-03 | PHASE3 |
| NCT07509749 | RECRUITING | GVHD, Acute; Stem Cell Transplant Complications |
Daihong Liu |
2025-06-30 | PHASE2 |
| NCT07594912 | NOT_YET_RECRUITING | Thyroid Eye Disease, TED; Graves Ophthalmopathy; Optic Neuropathy |
Sun Yat-sen University |
2026-08 | PHASE2 |
| NCT07623668 | RECRUITING | Optic Neuritis |
Oculis |
2026-05-28 | PHASE3 |
| NCT07255248 | RECRUITING | Hoffa's Fat Pad Impingement |
Boston Children's Hospital |
2026-03-01 | PHASE4 |
| NCT07052929 | RECRUITING | X-Linked Myotubular Myopathy |
Astellas Gene Therapies |
2025-12-15 | PHASE1; PHASE2 |
| NCT07180277 | NOT_YET_RECRUITING | Traumatic Brain Injury |
Zhangjiagang First People's Hospital |
2025-10-01 | PHASE4 |
| NCT06489626 | WITHDRAWN | Arthritis Knee; Knee Osteoarthritis; Pain, Postoperative |
F. Johannes Plate |
2025-11-01 | PHASE4 |
| NCT05736549 | RECRUITING | Total Knee Replacement; Knee Arthroplasty |
Yale University |
2023-02-07 | PHASE2 |
| NCT07353749 | NOT_YET_RECRUITING | Unruptured Intracranial Aneurysms; Cerebrovascular Event; Hemorrhagic Stroke; Methylprednisolone; Flow Diverter |
Duan Chuanzhi |
2026-01-30 | PHASE4 |
| NCT04151082 | RECRUITING | Cranial Nerve Disorder; Head and Neck Carcinoma; Oropharyngeal Carcinoma |
M.D. Anderson Cancer Center |
2019-10-16 | PHASE1; PHASE2 |
| NCT07762105 | NOT_YET_RECRUITING | Thyroid Eye Disease; Graves Ophthalmopathy; Graves Orbitopathy |
Banu Aji Dibyasakti |
2026-08-30 | PHASE1 |
| NCT04411654 | ACTIVE_NOT_RECRUITING | Gaucher Disease, Type 2 |
Prevail Therapeutics |
2021-06-29 | PHASE1; PHASE2 |
| NCT06356571 | RECRUITING | Plasma Cell Myeloma Refractory |
Sanofi |
2025-03-17 | PHASE2 |
| NCT06268704 | RECRUITING | Sacroiliac Joint Dysfunction; Sacro-Iliac Spondylosis |
University of New Mexico |
2024-03-27 | PHASE4 |
| NCT07054801 | RECRUITING | Headaches Associated With Subarachnoid Hemorrhage (SAH) |
Daniel Raper, MBBS |
2026-06-23 | PHASE2 |
| NCT03579875 | RECRUITING | Fanconi Anemia; Severe Aplastic Anemia; Myelodysplastic Syndromes; T Cell Receptor Alpha/Beta Depletion; Telomere Biology Disorder; Bone Marrow Failure; Dyskeratosis Congenita; Telomere Biology Disorders |
Masonic Cancer Center, University of Minnesota |
2018-11-13 | PHASE2 |
| NCT05842681 | RECRUITING | Idiopathic Pulmonary Fibrosis |
Assiut University |
2023-06-01 | |
| NCT06763848 | RECRUITING | Neuromyelitis Optica Spectrum Disorders |
Third Affiliated Hospital, Sun Yat-Sen University |
2025-04-25 | |
| NCT07101445 | RECRUITING | Multiple Myeloma |
Emory University |
2025-09-24 | PHASE4 |
| NCT06921616 | NOT_YET_RECRUITING | Stroke; Intracerebral Hemorrhage Lobar; Methylprednisolone; Surgery |
Yong Jiang |
2025-05-01 | PHASE4 |
| NCT07077486 | RECRUITING | Lupus or SLE; Interstitial Lung Disease; Systemic Lupus Erythematosus |
Tongji Hospital |
2025-08-25 | PHASE4 |
| NCT05974462 | RECRUITING | Acute Myocarditis |
University Hospital, Antwerp |
2024-05-24 | PHASE3 |
| NCT07185633 | NOT_YET_RECRUITING | aGVHD |
Bin Gu |
2025-10-01 | PHASE2 |
| NCT04787744 | RECRUITING | Prostate Cancer; Oligometastasis; Oligorecurrence; Recurrent Prostate Cancer; Metastatic Prostate Cancer; De Novo Prostate Cancer |
VA Office of Research and Development |
2021-07-01 | PHASE2; PHASE3 |
| NCT06809998 | RECRUITING | Total Knee Anthroplasty; Osteoarthritis(Primary); Osteoarthritis (OA) of the Knee; Bilateral Knee Osteoarthritis |
Unity Health Toronto |
2025-01-24 | PHASE1; PHASE2 |
| NCT06504030 | NOT_YET_RECRUITING | Hemophagocytic Lymphohistiocytoses |
The First Affiliated Hospital of Soochow University |
2024-08-01 | PHASE4 |
| NCT07393503 | ENROLLING_BY_INVITATION | Musculoskeletal Pain |
State University of New York at Buffalo |
2025-09-17 | PHASE4 |
| NCT06841705 | RECRUITING | Immune Checkpoint Inhibitor-Related Colitis |
Shilpa Grover, MD, MPH |
2025-07-15 | PHASE2 |
| NCT06081101 | NOT_YET_RECRUITING | Sacro-iliac Joint Pain |
McMaster University |
2025-01 | EARLY_PHASE1 |
| NCT06510114 | NOT_YET_RECRUITING | Graves Ophthalmopathy |
Third Affiliated Hospital, Sun Yat-Sen University |
2024-07 | PHASE4 |
| NCT06768294 | NOT_YET_RECRUITING | Calcium Pyrophosphate Deposition Disease; Chondrocalcinosis |
I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio |
2025-01 | PHASE2 |
| NCT07187037 | NOT_YET_RECRUITING | Neuromuscular Block, Residual; Pain; Postoperative Nausea |
Konya City Hospital |
2025-10-01 | |
| NCT07184840 | ACTIVE_NOT_RECRUITING | Neuromyelitis Optica Spectrum Disorder Attack |
Tianjin Medical University General Hospital |
2025-09-09 | PHASE2 |
| NCT03098225 | NOT_YET_RECRUITING | Thyroid Associated Ophthalmopathy |
University of Pisa |
2024-01-01 | PHASE4 |
| NCT06656962 | ACTIVE_NOT_RECRUITING | Antineutrophil Cytoplasmic Antibody (ANCA)-associated Nephritis (AAGN) |
Renmin Hospital of Wuhan University |
2024-10-10 | PHASE1; PHASE2 |
| NCT04918953 | NOT_YET_RECRUITING | Outcome |
Second Affiliated Hospital, Zhejiang University, School of Medicine |
2021-06-02 | PHASE2 |
| NCT05704049 | ACTIVE_NOT_RECRUITING | Relapsed/Refractory Multiple Myeloma |
Sanofi |
2023-04-05 | PHASE2 |
| NCT07175623 | COMPLETED | Neuromuscular Block, Residual; Pain Management; Postoperative Nausea |
Konya City Hospital |
2025-09-16 | |
| NCT04826237 | TERMINATED | Sudden Sensorineural Hearing Loss |
Northwestern University |
2023-02-09 | PHASE4 |
| NCT04163536 | UNKNOWN | Chronic Obstructive Pulmonary Disease |
Versailles Hospital |
2021-10-25 | PHASE3 |
| NCT07349680 | COMPLETED | Postherpetic Neuralgia |
Assiut University |
2023-03-15 | PHASE3 |
| NCT05859269 | COMPLETED | Knee Arthritis |
Emory University |
2023-10-16 | PHASE4 |
| NCT06462781 | COMPLETED | Refractory Migraine |
The Cooper Health System |
2024-03-15 | PHASE1 |
| NCT06496997 | COMPLETED | Acute Respiratory Distress Syndrome |
Fayoum University |
2024-08-01 | PHASE2; PHASE3 |
| NCT03942887 | UNKNOWN | ANCA Associated Vasculitis |
Leiden University Medical Center |
2019-05-03 | PHASE3 |
| NCT04192656 | RECRUITING | Sudden Hearing Loss; Obstructive Sleep Apnea |
Beijing Tsinghua Chang Gung Hospital |
2019-11-01 | PHASE4 |
| NCT06710704 | COMPLETED | Transcutaneous; Pulsed Radiofrequency; Corticosteroids Injections; Pain; Lateral Epicondylitis |
Tanta University |
2024-04-01 | |
| NCT05823675 | UNKNOWN | Acute Graft Versus Host Disease |
Biotech Pharmaceutical Co., Ltd. |
2023-05-19 | PHASE1 |
| NCT06076824 | UNKNOWN | Heart Block; Aortic Stenosis; Bundle-Branch Block |
Hospital General Universitario de Alicante |
2023-08-12 | PHASE4 |
| NCT05666336 | UNKNOWN | Systemic Lupus Erythematosus |
Fen Li |
2022-12-31 | PHASE4 |
| NCT02422368 | WITHDRAWN | Thyroid Eye Disease |
Iran University of Medical Sciences |
2022-09-01 | PHASE2; PHASE3 |
| NCT04666129 | COMPLETED | Metastatic Castration-Resistant Prostate Cancer; Metastatic Castration-Sensitive Prostate Cancer; Non-Metastatic Castration-Resistant Prostate Cancer |
Sumitomo Pharma America, Inc. |
2021-02-18 | PHASE1 |
| NCT06343792 | Not yet recruiting | Steroid Refractory GVHD |
ReAlta Life Sciences Inc. |
2024-05 | Phase 2 |
| NCT06131593 | COMPLETED | Local Anesthetic; Ultrasound; Pain, Acute |
Kasr El Aini Hospital |
2023-12-01 | |
| NCT05863936 | UNKNOWN | Lupus Nephritis; Remission; Safety Issues |
Nanjing University School of Medicine |
2023-04-01 | PHASE3 |
| NCT06297486 | Recruiting | Hemophilia A |
Spark Therapeutics Inc. |
2024-03-13 | Phase 3 |
| NCT03875690 | ACTIVE_NOT_RECRUITING | Elective Surgery for Any Digestive Cancer |
Centre Hospitalier Universitaire Dijon |
2019-07-02 | PHASE3 |
| NCT04773392 | TERMINATED | Kidney Transplantation; Kidney Transplant Rejection |
University of Southern California |
2021-11-23 | PHASE4 |
| NCT01331018 | TERMINATED | Fanconi Anemia |
Fred Hutchinson Cancer Center |
2012-02-22 | PHASE1 |
| NCT06000709 | UNKNOWN | Osteoarthritis, Knee; Chronic Knee Pain |
University of Manitoba |
2023-10-20 | PHASE4 |
| NCT05462730 | COMPLETED | ST Elevation Myocardial Infarction; Inflammatory Response; Myocardial Reperfusion Injury; Myocardial Injury |
Thomas Engstrom |
2022-11-14 | PHASE2 |
| NCT04918147 | TERMINATED | IgG4 Related Disease; IgG4-RD |
National Institute of Allergy and Infectious Diseases (NIAID) |
2021-10-13 | PHASE2 |
| NCT06552442 | COMPLETED | Ischemia-reperfusion Injury; No-reflow |
Amosov National Institute of Cardiovascular Surgery |
2020-09-05 | PHASE2 |
| NCT05604859 | UNKNOWN | Severe Fever With Thrombocytopenia Syndrome |
Qin Ning |
2022-08-19 | PHASE4 |
| NCT04833374 | UNKNOWN | IgA Nephropathy |
Sixth Affiliated Hospital, Sun Yat-sen University |
2021-05-24 | PHASE3 |
| NCT04438382 | TERMINATED | Hematopoietic and Lymphoid Cell Neoplasm; Malignant Solid Neoplasm; Steroid-Refractory Pneumonitis |
ECOG-ACRIN Cancer Research Group |
2021-01-07 | PHASE2 |
| NCT03636165 | UNKNOWN | Pain, Postoperative; Post-Craniotomy Headache |
Beijing Tiantan Hospital |
2022-09-01 | PHASE4 |
| NCT05587673 | COMPLETED | Inflammatory Bowel Diseases; Crohn Disease; Ulcerative Colitis; Indeterminate Colitis |
Stanford University |
2022-10-06 | PHASE1 |
| NCT04988425 | UNKNOWN | Spinal Cord Injuries |
Shanghai Changzheng Hospital |
2022-09-01 | PHASE1; PHASE2 |
| NCT02348216 | COMPLETED | Refractory Diffuse Large B Cell Lymphoma (DLBCL); Relapsed Diffuse Large B-Cell Lymphoma; Transformed Follicular Lymphoma (TFL); Primary Mediastinal B-cell Lymphoma (PMBCL); High Grade B-cell Lymphoma (HGBCL) |
Kite, A Gilead Company |
2015-04-21 | PHASE1; PHASE2 |
| NCT05752305 | COMPLETED | Inflammation; Pain, Postoperative; Trismus |
Universidad de Granada |
2022-01-15 | PHASE2; PHASE3 |
| NCT05137496 | UNKNOWN | Macrophage Activation Syndrome |
Beijing Friendship Hospital |
2022-06-01 | PHASE3 |
| NCT05655130 | TERMINATED | Fractures, Bone; Fractures, Closed; Radius Fracture Distal |
Indiana Hand to Shoulder Center |
2018-11-06 | PHASE1 |
| NCT03266146 | COMPLETED | Drug-induced Liver Injury,Chronic |
Beijing 302 Hospital |
2017-09-02 | PHASE1; PHASE2 |
| NCT05368181 | UNKNOWN | GVHD,Acute; Stem Cell Transplant Complications |
Sichuan University |
2022-05-01 | PHASE2 |
| NCT05302388 | COMPLETED | Asymptomatic Hyperuricemia |
Shanghai Institute Of Biological Products |
2022-04-11 | PHASE1 |
| NCT04485429 | WITHDRAWN | COVID-19 |
D'Or Institute for Research and Education |
2020-07-20 | PHASE3 |
| NCT04900220 | COMPLETED | Trigger Finger |
West Virginia University |
2021-09-15 | PHASE4 |
| NCT04876534 | UNKNOWN | Graves Ophthalmopathy |
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico |
2019-12-18 | PHASE2 |
| NCT06041451 | UNKNOWN | Guillain-Barre Syndrome |
First Affiliated Hospital of Wenzhou Medical University |
2013-01-02 | PHASE4 |
| NCT04903054 | WITHDRAWN | Kidney Transplantation; Renal Transplant Recipients |
National Institute of Allergy and Infectious Diseases (NIAID) |
2022-01-10 | PHASE2 |
| NCT04560582 | Withdrawn | Kidney Transplant; Complications|Kidney Transplant Rejection|Kidney Transplant Failure |
University of Minnesota |
2022-09-22 | -- |
| NCT04938037 | COMPLETED | Chronic Shoulder Pain |
TC Erciyes University |
2021-06-01 | |
| NCT05134181 | UNKNOWN | Sacroiliac Joint Arthritis |
Mansoura University |
2021-08-01 | PHASE2 |
| NCT03794492 | COMPLETED | Kidney Transplant |
Chong Kun Dang Pharmaceutical |
2018-03-31 | PHASE4 |
| NCT04046549 | COMPLETED | Allografts; Rejection; Transplant, Kidney; Transplant Rejection; Kidney Transplantation |
Amgen |
2019-10-30 | PHASE2 |
| NCT05339542 | COMPLETED | Plantar Fascitis |
Minia University |
2022-03-10 | |
| NCT03973177 | WITHDRAWN | Pain, Chronic |
Northwestern University |
2019-05-24 | PHASE4 |
| NCT03978559 | UNKNOWN | Pneumocystis Pneumonia |
Bin Du |
2019-08-14 | PHASE4 |
| NCT04622917 | COMPLETED | Rhinitis, Allergic, Seasonal; Hay Fever; Pollen Allergy; Allergic Rhinitis |
Karolinska Institutet |
2019-04-10 | PHASE4 |
| NCT04515966 | UNKNOWN | Carpal Tunnel Syndrome |
Mercy Health Ohio |
2020-12-01 | PHASE4 |
| NCT02798523 | COMPLETED | Normal Physiology |
National Institute of Allergy and Infectious Diseases (NIAID) |
2017-01-24 | PHASE1 |
| NCT03113695 | COMPLETED | Richter's Syndrome; CLL |
University of California, San Diego |
2017-12-20 | PHASE1 |
| NCT04294459 | TERMINATED | Immune System Disorder |
Sanofi |
2020-06-18 | PHASE1; PHASE2 |
| NCT04808856 | UNKNOWN | Gout |
Shanghai 10th People's Hospital |
2021-04-01 | |
| NCT05413902 | COMPLETED | Pain Management; Posterior Spinal Fusion |
University of Puerto Rico |
2021-04-05 | PHASE4 |
| NCT02166463 | ACTIVE_NOT_RECRUITING | Ann Arbor Stage IIB Hodgkin Lymphoma; Ann Arbor Stage IIIB Hodgkin Lymphoma; Ann Arbor Stage IVA Hodgkin Lymphoma; Ann Arbor Stage IVB Hodgkin Lymphoma; Childhood Hodgkin Lymphoma; Classic Hodgkin Lymphoma |
National Cancer Institute (NCI) |
2015-03-19 | PHASE3 |
| NCT04129697 | UNKNOWN | Dexamethasone or Methylprednisolone; Sudden Hearing Loss; Intratympanic Steroid |
Second Affiliated Hospital, Zhejiang University, School of Medicine |
2020-01-01 | |
| NCT02867800 | COMPLETED | Sickle Cell Disease; Graft Versus Host Disease |
Monica Bhatia |
2016-07 | PHASE1 |
| NCT05649878 | COMPLETED | Methylprednisone Administration; Intranasal Administration; Intravenous Administration; Healthy Subjects |
Edda Sciutto Conde |
2021-11-05 | |
| NCT05487521 | COMPLETED | Language Disorders in Children |
Ain Shams University |
2020-02-20 | PHASE3 |
| NCT02909335 | WITHDRAWN | Liver Transplantation |
Rennes University Hospital |
2016-11 | PHASE3 |
| NCT04593706 | UNKNOWN | Keloid; Hypertrophic Scar; Scars; Scarring |
Tel-Aviv Sourasky Medical Center |
2020-11-01 | |
| NCT04810819 | UNKNOWN | Methylprednisolone;Dihydroxypropyltheophylline;One Lung Ventilation;Respiratory Dynamics |
Qianfoshan Hospital |
2021-07-01 | |
| NCT05037994 | COMPLETED | Pain, Shoulder |
Zagazig University |
2021-04-01 | |
| NCT04162314 | UNKNOWN | Uveitis |
Fakultas Kedokteran Universitas Indonesia |
2020-01-21 | PHASE2; PHASE3 |
| NCT03492255 | TERMINATED | Systemic Lupus Erythematosus (SLE) |
University of Sao Paulo General Hospital |
2018-04-12 | |
| NCT03059979 | UNKNOWN | Systemic Sclerosis; Raynaud Phenomena |
Radboud University Medical Center |
2017-01 | EARLY_PHASE1 |
| NCT04078139 | UNKNOWN | Pain, Postoperative |
Beijing Tiantan Hospital |
2021-03-05 | PHASE4 |
| NCT04816253 | COMPLETED | Preventing Postextraction Complication |
Al-Azhar University |
2021-02-10 | |
| NCT04074187 | COMPLETED | Thrombotic Thrombocytopenic Purpura |
Sanofi |
2019-10-21 | PHASE2; PHASE3 |
| NCT04402177 | UNKNOWN | Hypersensitivity Pneumonitis |
Al-Azhar University |
2020-07-01 | PHASE4 |
| NCT03110848 | COMPLETED | Thyroid Associated Ophthalmopathy; Hypercholesterolemia |
University of Pisa |
2020-06-01 | PHASE2 |
| NCT04493463 | COMPLETED | Postoperative Pain; Neurosurgery |
Beijing Tiantan Hospital |
2020-07-31 | PHASE4 |
| NCT01941589 | COMPLETED | Ulcerative Colitis |
Sheba Medical Center |
2013-09 | PHASE4 |
| NCT04007328 | UNKNOWN | Pneumonia, Bacterial |
Taipei Medical University WanFang Hospital |
2019-06-15 | PHASE2; PHASE3 |
| NCT03994731 | COMPLETED | Gout |
Amgen |
2019-06-13 | PHASE4 |
| NCT04796493 | Active not recruiting | Mesenteric Traction Syndrome |
Rigshospitalet Denmark |
2021-03-16 | -- |
| NCT04780581 | Terminated | Corona Virus Infection |
Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León|Instituto de Investigación Biomédica de Salamanca |
2021-02-01 | Phase 4 |
| NCT03564106 | COMPLETED | Pain Management |
Assiut University |
2019-03-01 | PHASE2; PHASE3 |
| NCT05015322 | COMPLETED | Shoulder Impingement; Ultrasound Guided Injection |
Bursa Yuksek Ihtisas Training and Research Hospital |
2017-01-01 | PHASE4 |
| NCT06790615 | COMPLETED | Ganglion Cyst |
Benazir Bhutto Hospital, Rawalpindi |
2020-06-01 | PHASE1; PHASE2 |
| NCT04559113 | UNKNOWN | SARS-CoV Infection; SARS (Severe Acute Respiratory Syndrome) |
Lahore General Hospital |
2020-05-01 | |
| NCT03852537 | COMPLETED | Pneumonia |
Mayo Clinic |
2019-12-02 | PHASE2 |
| NCT04499313 | UNKNOWN | Covid19; ARDS |
Chattogram General Hospital |
2020-08-02 | PHASE3 |
| NCT02539394 | COMPLETED | Cervical Disc Herniation; Cervical Degenerative Disc Disease; Cervical Spondylotic Myelopathy; Dysphagia; Osteoarthritis of Cervical Spine |
Hospital for Special Surgery, New York |
2015-08 | |
| NCT02462252 | COMPLETED | Aplastic Anemia; Hypoplastic Myelodysplastic Syndrome |
BioLineRx, Ltd. |
2015-10 | PHASE2 |
| NCT04220632 | TERMINATED | GVHD,Acute |
Innovent Biologics (Suzhou) Co. Ltd. |
2020-06-18 | PHASE1; PHASE2 |
| NCT02540395 | COMPLETED | Disorder Related to Renal Transplantation; Effects of Immunosuppressant Therapy |
Prof. Dr. Petra Reinke |
2015-03 | |
| NCT02647255 | TERMINATED | Glomerulonephritis, IGA; Kidney Diseases; Acute Renal Insufficiency; Rapidly Progressive Glomerulonephritis |
Peking University First Hospital |
2016-03 | PHASE2; PHASE3 |
| NCT04355247 | UNKNOWN | Covid-19 |
Auxilio Mutuo Cancer Center |
2020-04-14 | PHASE2 |
| NCT02532777 | UNKNOWN | Henoch-Schoenlein Purpura Nephritis |
Nanjing Children's Hospital |
2015-08 | PHASE2 |
| NCT03974867 | UNKNOWN | Vestibular Vertigo; Sudden Hearing Loss |
Eye & ENT Hospital of Fudan University |
2019-07 | |
| NCT04343729 | COMPLETED | SARS-CoV Infection; Severe Acute Respiratory Syndrome (SARS) Pneumonia |
Fundação de Medicina Tropical Dr. Heitor Vieira Dourado |
2020-04-18 | PHASE2 |
| NCT04341038 | UNKNOWN | COVID-19; Lung Injury |
Hospital Universitari de Bellvitge |
2020-04-01 | PHASE3 |
| NCT04263402 | UNKNOWN | 2019-nCoV Severe Pneumonia |
Tongji Hospital |
2020-02-01 | PHASE4 |
| NCT03529929 | WITHDRAWN | Aging |
Texas A&M University |
2019-06-01 | PHASE3 |
| NCT04244591 | COMPLETED | COVID-19 Infections |
Peking Union Medical College Hospital |
2020-01-26 | PHASE2; PHASE3 |
| NCT03018535 | UNKNOWN | Glomerulonephritis, Membranous |
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia |
2012-01 | PHASE3 |
| NCT02303587 | COMPLETED | Mycoplasma Pneumoniae Pneumonia |
Beijing Children's Hospital |
2014-12 | |
| NCT03593902 | TERMINATED | Systemic Sclerosis; Scleroderma |
Northwestern University |
2018-05-17 | PHASE2; PHASE3 |
| NCT02378298 | COMPLETED | Ophthalmopathy, Thyroid-Associated |
Göteborg University |
2011-12 | PHASE4 |
| NCT03342638 | TERMINATED | Multiple Sclerosis, Relapsing-Remitting |
Northwestern University |
2017-11-08 | PHASE3 |
| NCT03694821 | TERMINATED | Osteoarthritis |
UConn Health |
2018-07-05 | PHASE4 |
| NCT01955187 | COMPLETED | MEMBRANOUS NEPHROPATHY |
Hospital Universitario 12 de Octubre |
2014-01 | PHASE3 |
| NCT03082092 | COMPLETED | Osteoarthritis, Knee |
Queen Elizabeth Hospital, Hong Kong |
2017-06-01 | PHASE4 |
| NCT03308084 | COMPLETED | Dysphasia |
Rush University Medical Center |
2015-11-13 | PHASE3 |
| NCT02545959 | COMPLETED | Multiple Sclerosis, Chronic Progressive; Nervous System Diseases |
Centre Hospitalier de PAU |
2015-11-30 | PHASE2 |
| NCT03466801 | TERMINATED | Idiopathic Membranous Nephropathy |
Wenhu Liu |
2018-03-20 | |
| NCT02550652 | COMPLETED | Lupus Nephritis |
Hoffmann-La Roche |
2015-11-13 | PHASE2 |
| NCT02077556 | COMPLETED | Drug Interaction Potentiation |
National Taiwan University Hospital |
2014-04 | PHASE4 |
| NCT03387046 | TERMINATED | Multiple Sclerosis, Relapsing-Remitting |
Merck KGaA, Darmstadt, Germany |
2018-03-26 | PHASE2 |
| NCT02243436 | COMPLETED | CLASSICAL HODGKIN LYMPHOMA |
Grupo Español de Linfomas y Transplante Autólogo de Médula Ósea |
2014-11-11 | PHASE1; PHASE2 |
| NCT03948191 | COMPLETED | Thyroid-Associated Ophthalmopathy |
Dalian University |
2017-10-16 | PHASE4 |
| NCT02444728 | TERMINATED | Thrombocytopenia |
Chinese SLE Treatment And Research Group |
2015-07 | PHASE3 |
| NCT00732498 | COMPLETED | Lymphoma |
University of Arizona |
2006-05-15 | PHASE2 |
| NCT01809132 | COMPLETED | Acute Alcoholic Hepatitis |
Mack Mitchell |
2013-09 | PHASE2; PHASE3 |
| NCT05707572 | COMPLETED | Morton Neuroma |
Dundee Podiatry Clinic |
2014-09 | |
| NCT01086540 | COMPLETED | Systemic Sclerosis-Associated PAH |
National Institute of Allergy and Infectious Diseases (NIAID) |
2011-06-24 | PHASE2 |
| NCT03094663 | COMPLETED | Knee Arthropathy |
Hospital for Special Surgery, New York |
2017-02-28 | PHASE4 |
| NCT01900093 | UNKNOWN | Multiple Sclerosis |
Aaron Miller |
2013-07 | |
| NCT02953678 | COMPLETED | Graft-versus-host Disease (GVHD) |
Incyte Corporation |
2016-12-30 | PHASE2 |
| NCT02293109 | COMPLETED | Contiguous Stage II Adult Lymphoblastic Lymphoma; Noncontiguous Stage II Adult Lymphoblastic Lymphoma; Stage I Adult Lymphoblastic Lymphoma; Stage III Adult Lymphoblastic Lymphoma; Stage IV Adult Lymphoblastic Lymphoma; Untreated Adult Acute Lymphoblastic Leukemia |
Mehrdad Abedi, MD |
2015-12-17 | PHASE1 |
| NCT02424435 | COMPLETED | Friedreich Ataxia |
Children's Hospital of Philadelphia |
2015-06 | EARLY_PHASE1 |
| NCT02757196 | UNKNOWN | Immune Thrombocytopenia |
Peking University People's Hospital |
2016-05 | PHASE2 |
| NCT02666703 | COMPLETED | Cardiopulmonary Bypass |
University Medical Centre Ljubljana |
2016-02-01 | PHASE3 |
| NCT02680548 | COMPLETED | CHRONIC POST-TRAUMATIC NEUROPATHIC PAIN IN ANKLE AND FOOT |
University Health Network, Toronto |
2015-11 | EARLY_PHASE1 |
| NCT02049073 | WITHDRAWN | Noise-induced Hearing Loss |
Washington University School of Medicine |
2017-10-31 | PHASE1; PHASE2 |
| NCT01156883 | COMPLETED | Leukemia |
Gruppo Italiano Malattie EMatologiche dell'Adulto |
2010-04 | |
| NCT00003270 | COMPLETED | Graft Versus Host Disease; Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes |
Roswell Park Cancer Institute |
1997-09-04 | PHASE2 |
| NCT02887976 | COMPLETED | Prostate Cancer |
GU Research Network, LLC |
2016-09 | PHASE3 |
| NCT02375867 | COMPLETED | Fulminant Hepatic Failure |
National Liver Institute, Egypt |
2015-01 | PHASE4 |
| NCT02426164 | WITHDRAWN | Pain, Postoperative; Arthroplasty, Replacement, Knee; Osteoarthritis |
Miller Orthopedic Specialists |
2015-06 | PHASE4 |
| NCT02199041 | TERMINATED | Hematological Malignancies |
St. Jude Children's Research Hospital |
2014-07-11 | PHASE2 |
| NCT02552342 | UNKNOWN | Community Acquired Pneumonia |
Peking Union Medical College Hospital |
2015-05 | PHASE4 |
| NCT02403856 | COMPLETED | Calcifying Tendinitis of Shoulder |
Nantes University Hospital |
2015-04-04 | PHASE4 |
| NCT01875237 | TERMINATED | Leukemia; Myeloma; Myeloproliferative Diseases |
M.D. Anderson Cancer Center |
2013-12-27 | PHASE1; PHASE2 |
| NCT01445821 | TERMINATED | Scleroderma, Systemic |
Northwestern University |
2011-09-15 | PHASE3 |
| NCT02669303 | TERMINATED | Shoulder Impingement Syndrome |
American University of Beirut Medical Center |
2015-09 | |
| NCT02542592 | COMPLETED | Osteoarthrosis |
Rigshospitalet, Denmark |
2015-09 | PHASE2; PHASE3 |
| NCT02652390 | COMPLETED | Carpal Tunnel Syndrome |
Region Skane |
2016-02 | PHASE4 |
| NCT02711449 | COMPLETED | Suspected Appendicitis |
Jakob Kleif |
2016-04 | PHASE2 |
| NCT01790594 | TERMINATED | Simultaneous Kidney and Pancreas Transplantation |
National Institute of Allergy and Infectious Diseases (NIAID) |
2013-02 | PHASE2 |
| NCT02569437 | TERMINATED | Polyp of Nasal Sinus |
Icahn School of Medicine at Mount Sinai |
2014-09 | PHASE2 |
| NCT01283009 | COMPLETED | Community Acquired Respiratory Disease Syndrome |
VA Office of Research and Development |
2012-01-09 | PHASE3 |
| NCT02576249 | COMPLETED | Osteoarthritis |
Mayo Clinic |
2015-10 | PHASE4 |
| NCT01974024 | COMPLETED | Dexamethasone-induced Hiccup in Chemotherapy |
Chung-Ang University |
2013-10-01 | PHASE3 |
| NCT02614612 | COMPLETED | Graft-versus-host Disease (GVHD) |
Incyte Corporation |
2015-12 | PHASE1 |
| NCT02304094 | UNKNOWN | Neuroma, Human Forefoot |
Queen Margaret University |
2015-10 | |
| NCT02319343 | COMPLETED | Osteoarthrosis |
Rigshospitalet, Denmark |
2015-01 | PHASE3 |
| NCT01783847 | COMPLETED | Traumatic Optic Neuropathy |
Tehran University of Medical Sciences |
2015-02 | PHASE1; PHASE2 |
| NCT01856257 | TERMINATED | Primary Renal Allograft Candidate; Kidney Transplantation |
National Institute of Allergy and Infectious Diseases (NIAID) |
2013-07 | PHASE2 |
| NCT00376077 | COMPLETED | Immune Thrombocytopenic Purpura |
The Hospital for Sick Children |
2005-08 | PHASE3 |
| NCT00920153 | TERMINATED | Lymphoma |
French Innovative Leukemia Organisation |
2008-05 | PHASE3 |
| NCT01757899 | WITHDRAWN | Acute Lung Injury; Acute Respiratory Distress Syndrome |
Universidade Federal do Rio de Janeiro |
2014-01 | PHASE2 |
| NCT01093586 | COMPLETED | Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome; Adult Acute Lymphoblastic Leukemia in Remission; Adult Acute Megakaryoblastic Leukemia (M7); Adult Acute Minimally Differentiated Myeloid Leukemia (M0); Adult Acute Monoblastic Leukemia (M5a); Adult Acute Monocytic Leukemia (M5b); Adult Acute Myeloid Leukemia in Remission; Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities; Adult Acute Myeloid Leukemia With t(16;16)(p13;q22); Adult Erythroleukemia (M6a); Adult Nasal Type Extranodal NK/T-cell Lymphoma; Adult Pure Erythroid Leukemia (M6b); B-cell Adult Acute Lymphoblastic Leukemia; B-cell Childhood Acute Lymphoblastic Leukemia; Blastic Phase Chronic Myelogenous Leukemia; Burkitt Lymphoma; Childhood Acute Erythroleukemia (M6); Childhood Acute Lymphoblastic Leukemia in Remission; Childhood Acute Megakaryocytic Leukemia (M7); Childhood Acute Minimally Differentiated Myeloid Leukemia (M0); Childhood Acute Monoblastic Leukemia (M5a); Childhood Acute Monocytic Leukemia (M5b); Childhood Acute Myeloid Leukemia in Remission; Childhood Chronic Myelogenous Leukemia; Childhood Diffuse Large Cell Lymphoma; Childhood Immunoblastic Large Cell Lymphoma; Childhood Myelodysplastic Syndromes; Childhood Nasal Type Extranodal NK/T-cell Lymphoma; Chronic Myelomonocytic Leukemia; Chronic Phase Chronic Myelogenous Leukemia; Cutaneous B-cell Non-Hodgkin Lymphoma; de Novo Myelodysplastic Syndromes; Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue; Juvenile Myelomonocytic Leukemia; Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable; Nodal Marginal Zone B-cell Lymphoma; Previously Treated Myelodysplastic Syndromes; Prolymphocytic Leukemia; Recurrent Adult Acute Lymphoblastic Leukemia; Recurrent Adult Acute Myeloid Leukemia; Recurrent Adult Burkitt Lymphoma; Recurrent Adult Diffuse Large Cell Lymphoma; Recurrent Adult Diffuse Mixed Cell Lymphoma; Recurrent Adult Diffuse Small Cleaved Cell Lymphoma; Recurrent Adult Grade III Lymphomatoid Granulomatosis; Recurrent Adult Immunoblastic Large Cell Lymphoma; Recurrent Adult Lymphoblastic Lymphoma; Recurrent Childhood Acute Lymphoblastic Leukemia; Recurrent Childhood Acute Myeloid Leukemia; Recurrent Childhood Anaplastic Large Cell Lymphoma; Recurrent Childhood Grade III Lymphomatoid Granulomatosis; Recurrent Childhood Large Cell Lymphoma; Recurrent Childhood Lymphoblastic Lymphoma; Recurrent Childhood Small Noncleaved Cell Lymphoma; Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma; Recurrent Grade 1 Follicular Lymphoma; Recurrent Grade 2 Follicular Lymphoma; Recurrent Grade 3 Follicular Lymphoma; Recurrent Mantle Cell Lymphoma; Recurrent Marginal Zone Lymphoma; Recurrent Mycosis Fungoides/Sezary Syndrome; Recurrent Small Lymphocytic Lymphoma; Refractory Chronic Lymphocytic Leukemia; Relapsing Chronic Myelogenous Leukemia; Secondary Acute Myeloid Leukemia; Secondary Myelodysplastic Syndromes; Secondary Myelofibrosis; Splenic Marginal Zone Lymphoma; Stage I Chronic Lymphocytic Leukemia; Stage II Chronic Lymphocytic Leukemia; Stage III Chronic Lymphocytic Leukemia; Stage IV Chronic Lymphocytic Leukemia; T-cell Adult Acute Lymphoblastic Leukemia; T-cell Childhood Acute Lymphoblastic Leukemia; T-cell Large Granular Lymphocyte Leukemia; Waldenstrom Macroglobulinemia |
Case Comprehensive Cancer Center |
2007-09 | PHASE2 |
| NCT02140632 | COMPLETED | Carpal Tunnel Syndrome; Local Steroid Injection; Wrist Splinting |
Kwong Wah Hospital |
2013-12 | PHASE4 |
| NCT01397552 | TERMINATED | Lumbar Spine Disc Herniation; Lumbar Radiculitis; Lumbar Back Pain |
State University of New York - Upstate Medical University |
2009-09 | |
| NCT01652417 | TERMINATED | Renal Sarcoidosis |
Assistance Publique - Hôpitaux de Paris |
2012-10 | |
| NCT00879931 | COMPLETED | Elective Cardiac Surgery |
University Hospital, Ghent |
2013-01 | PHASE2 |
| NCT01436305 | TERMINATED | Kidney Transplantation; Renal Transplantation |
National Institute of Allergy and Infectious Diseases (NIAID) |
2011-09 | PHASE2 |
| NCT00455312 | COMPLETED | Dyskeratosis Congenita; Aplastic Anemia |
Masonic Cancer Center, University of Minnesota |
2007-08 | PHASE2; PHASE3 |
| NCT02048358 | TERMINATED | Healthy Volunteers; Multiple Sclerosis |
BBB-Therapeutics B.V. |
2013-11 | PHASE1 |
| NCT02334475 | COMPLETED | Chronic Pain |
Post Graduate Institute of Medical Education and Research, Chandigarh |
2013-07 | |
| NCT02098330 | COMPLETED | Vestibular Neuritis |
Asan Medical Center |
2014-03 | PHASE3 |
| NCT01465334 | TERMINATED | CLL; SLL |
Dana-Farber Cancer Institute |
2011-12 | PHASE2 |
| NCT00400946 | COMPLETED | Drug/Agent Toxicity by Tissue/Organ; Leukemia |
Dana-Farber Cancer Institute |
2005-04 | PHASE3 |
| NCT02025309 | COMPLETED | Neuromuscular Monitoring; Sugammadex Effect |
Ankara University |
2013-12 | PHASE4 |
| NCT01105650 | COMPLETED | Ovarian Cancer; Fallopian Tube Cancer; Primary Peritoneal Cancer; Breast Cancer |
Masonic Cancer Center, University of Minnesota |
2010-07 | PHASE2 |
| NCT00458848 | COMPLETED | Leukemia |
Gruppo Italiano Malattie EMatologiche dell'Adulto |
2004-10 | PHASE2 |
| NCT00427388 | UNKNOWN | Cardiac Surgical Procedures; Cardiopulmonary Bypass; Systemic Inflammatory Response Syndrome |
Population Health Research Institute |
2007-06 | PHASE4 |
| NCT01710228 | WITHDRAWN | Multiple Sclerosis (MS) |
University of Texas Southwestern Medical Center |
2013-07 | PHASE2 |
| NCT01607580 | COMPLETED | Leukemia |
Peking University People's Hospital |
2012-06 | |
| NCT00076752 | COMPLETED | Lupus Erythematosus, Systemic |
National Cancer Institute (NCI) |
2004-01-30 | PHASE2 |
| NCT01726465 | TERMINATED | Ischemic Reperfusion Injury; Insufficiency; Hepatic, Postoperative; Liver Tumour |
Istituto Clinico Humanitas |
2012-11 | PHASE2 |
| NCT01969019 | UNKNOWN | Graves' Ophthalmopathy |
Ruijin Hospital |
2010-01 | PHASE4 |
| NCT01907204 | COMPLETED | Sinusitis |
Cliniques universitaires Saint-Luc- Université Catholique de Louvain |
2013-07 | PHASE2; PHASE3 |
| NCT01305837 | COMPLETED | Progressive Multiple Sclerosis |
Rigshospitalet, Denmark |
2011-04 | PHASE2 |
| NCT01670812 | UNKNOWN | Chronic Lymphocytic Leukemia |
The First Affiliated Hospital with Nanjing Medical University |
2012-01 | PHASE3 |
| NCT00984984 | UNKNOWN | Multiple Sclerosis, Relapsing-Remitting |
Rennes University Hospital |
2008-03 | PHASE3 |
| NCT01468415 | UNKNOWN | Back Pain |
Assaf-Harofeh Medical Center |
2011-06 | PHASE1 |
| NCT01652495 | COMPLETED | Tendinopathy; Adrenal Insufficiency |
Istituto Ortopedico Rizzoli |
2012-03 | PHASE4 |
| NCT01647685 | UNKNOWN | Atherosclerosis |
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) |
2012-05 | PHASE1; PHASE2 |
| NCT01790022 | UNKNOWN | Ankylosing Spondylitis |
Saratov State Medical University |
2012-07 | PHASE2 |
| NCT01219933 | COMPLETED | Rheumatoid Arthritis |
Hoffmann-La Roche |
2011-01 | PHASE4 |
| NCT01005914 | TERMINATED | Leukemia |
OHSU Knight Cancer Institute |
2009-06 | PHASE2 |
| NCT01382940 | COMPLETED | Rheumatoid Arthritis |
Hoffmann-La Roche |
2011-07-26 | PHASE4 |
| NCT01789892 | WITHDRAWN | Lung Cancer |
Ohio State University Comprehensive Cancer Center |
2011-06 | |
| NCT00771875 | COMPLETED | Graft Rejection |
University of Cincinnati |
2008-09 | PHASE2 |
| NCT00808210 | TERMINATED | Rheumatoid Arthritis |
Genentech, Inc. |
2009-03-05 | PHASE2 |
| NCT00248534 | TERMINATED | Lymphoma |
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins |
2005-09 | PHASE2 |
| NCT04528797 | COMPLETED | Brain Death |
Medical University of South Carolina |
2010-09-02 | |
| NCT00764413 | TERMINATED | Multiple Sclerosis |
Sykehuset Innlandet HF |
2009-04 | |
| NCT00109928 | COMPLETED | Lymphoma |
SWOG Cancer Research Network |
2005-09 | PHASE2 |
| NCT01405131 | WITHDRAWN | Therapeutic Equivalency |
Pfizer |
2012-01-01 | PHASE1 |
| NCT01191190 | COMPLETED | CLL |
Januario Castro, M.D. |
2010-08 | PHASE2 |
| NCT00908713 | COMPLETED | Community-Acquired Pneumonia |
Hospital Clinic of Barcelona |
2004-01 | PHASE4 |
| NCT01211665 | TERMINATED | Immune Reconstitution Inflammatory Syndrome; Leukoencephalopathy, Progressive Multifocal |
Biogen |
2010-09 | PHASE4 |
| NCT01039103 | TERMINATED | Acute Exacerbation of Remitting Relapsing Multiple Sclerosis; Clinically Isolated Syndrome |
Lakefront Biotherapeutics NV |
2009-12 | PHASE2 |
| NCT01071083 | COMPLETED | Relapsing Remitting Multiple Sclerosis |
Biogen |
2010-03 | PHASE2 |
| NCT01405170 | WITHDRAWN | Therapeutic Equivalency |
Pfizer |
2011-10-14 | PHASE1 |
| NCT00934843 | COMPLETED | Congenital Heart Disease; Disorder of Fetus or Newborn |
Medical University of South Carolina |
2007-03 | |
| NCT01106547 | COMPLETED | Hysterectomy; Methylprednisolone; Postoperative Pain |
Holbaek Sygehus |
2009-08 | PHASE4 |
| NCT01216631 | TERMINATED | Spondylarthropathies |
University of Leeds |
2010-09 | PHASE2 |
| NCT00539838 | TERMINATED | Systemic Lupus Erythematosus |
Genentech, Inc. |
2007-12-19 | PHASE3 |
| NCT01306955 | UNKNOWN | Behcet's Disease |
Tehran University of Medical Sciences |
2010-02 | PHASE4 |
| NCT00307671 | COMPLETED | Vasculitis; Wegener's Granulomatosis; Microscopic Polyangiitis; Churg-Strauss Syndrome; Polyarteritis Nodosa |
Assistance Publique - Hôpitaux de Paris |
2005-07 | PHASE4 |
| NCT00054236 | COMPLETED | Chronic Myeloproliferative Disorders; Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Diseases |
Case Comprehensive Cancer Center |
2002-05 | PHASE1 |
| NCT01308255 | COMPLETED | Rheumatoid Arthritis |
University of Leeds |
2006-09 | PHASE4 |
| NCT00968903 | COMPLETED | LOS; Postoperative Pain; Postoperative Nausea and Vomiting; Sleeping Quality; Fatigue; Inflammatory Response |
Hvidovre University Hospital |
2010-04 | PHASE4 |
| NCT00128180 | COMPLETED | Hantavirus Infections |
University of New Mexico |
2003-01 | PHASE2 |
| NCT00753792 | COMPLETED | Multiple Sclerosis |
Germans Trias i Pujol Hospital |
2008-11 | PHASE4 |
| NCT00609739 | TERMINATED | Leukemia |
Masonic Cancer Center, University of Minnesota |
1999-06 | PHASE1; PHASE2 |
| NCT00376480 | COMPLETED | Leukemia; Myelodysplastic Syndromes |
Dana-Farber Cancer Institute |
2005-06 | PHASE1 |
| NCT01217099 | TERMINATED | Refractory Mycoplasma Pneumoniae Pneumonia |
Chongqing Medical University |
2007-05 | |
| NCT00241254 | COMPLETED | Multiple Sclerosis, Chronic Progressive |
University Hospital, Bordeaux |
2005-12 | PHASE3 |
| NCT00346151 | TERMINATED | Renal Transplant |
National Institute of Allergy and Infectious Diseases (NIAID) |
2006-12 | PHASE2 |
| NCT01167946 | COMPLETED | Alopecia Totalis; Alopecia Universalis; Ophiasic Alopecia |
King Saud University |
2003-01 | PHASE4 |
| NCT00493116 | COMPLETED | Relapsing-Remitting Multiple Sclerosis |
Biogen |
2003-10 | PHASE4 |
| NCT00578305 | COMPLETED | Rheumatoid Arthritis |
Hoffmann-La Roche |
2007-11 | PHASE3 |
| NCT00066469 | COMPLETED | Lymphoproliferative Disorder |
Children's Oncology Group |
2004-04 | PHASE2 |
| NCT00627731 | COMPLETED | Asthma |
Hamamatsu University |
2007-06 | PHASE4 |
| NCT00097448 | COMPLETED | Sudden Deafness |
Massachusetts Eye and Ear Infirmary |
2004-12 | PHASE3 |
| NCT00057811 | COMPLETED | Childhood Burkitt Lymphoma; Childhood Diffuse Large Cell Lymphoma; Childhood Immunoblastic Large Cell Lymphoma; Stage I Childhood Large Cell Lymphoma; Stage I Childhood Small Noncleaved Cell Lymphoma; Stage II Childhood Large Cell Lymphoma; Stage II Childhood Small Noncleaved Cell Lymphoma; Stage III Childhood Large Cell Lymphoma; Stage III Childhood Small Noncleaved Cell Lymphoma; Stage IV Childhood Large Cell Lymphoma; Stage IV Childhood Small Noncleaved Cell Lymphoma; Untreated Childhood Acute Lymphoblastic Leukemia |
Children's Oncology Group |
2004-06 | PHASE2 |
| NCT00623766 | COMPLETED | Melanoma |
Bristol-Myers Squibb |
2008-07 | PHASE2 |
| NCT02252809 | COMPLETED | Innate Immunity |
Brugmann University Hospital |
2008-11 | EARLY_PHASE1 |
| NCT00379431 | COMPLETED | Early and Severe Systemic Sclerosis |
University Hospital, Ghent |
2006-11-27 | PHASE2 |
| NCT00243412 | COMPLETED | Rheumatoid Arthritis |
Genentech, Inc. |
2005-08 | PHASE2 |
| NCT00558181 | COMPLETED | Chronic B-Lymphocytic Leukemia |
Vilnius University |
2007-09 | PHASE2 |
| NCT00332696 | COMPLETED | Peritoneal Neoplasms; Intestinal Obstruction; Carcinomatosis |
Novartis Pharmaceuticals |
2005-09 | PHASE2 |
| NCT00299104 | COMPLETED | Rheumatoid Arthritis |
Genentech, Inc. |
2006-01 | PHASE3 |
| NCT00381810 | TERMINATED | Lupus Erythematosus, Systemic |
Genentech, Inc. |
2006-06-22 | PHASE3 |
| NCT00127985 | UNKNOWN | Multiple Organ Dysfunction Syndrome |
Hospital Universitario Principe de Asturias |
2005-08 | PHASE4 |
| NCT00348413 | COMPLETED | Graves Ophthalmopathy |
Singapore National Eye Centre |
2003-06 | |
| NCT00299130 | COMPLETED | Rheumatoid Arthritis |
Genentech, Inc. |
2005-10 | PHASE3 |
| NCT00521430 | COMPLETED | Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes; Nonmalignant Neoplasm; Unspecified Adult Solid Tumor, Protocol Specific |
Asan Medical Center |
2004-04 | |
| NCT00003728 | UNKNOWN | Leukemia; Lymphoma |
European Organisation for Research and Treatment of Cancer - EORTC |
1998-12 | PHASE3 |
| NCT00608517 | TERMINATED | Graft Versus Host Disease; Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes |
Vanderbilt-Ingram Cancer Center |
2005-09 | |
| NCT00492973 | COMPLETED | Osteoarthritis; Post-traumatic; Arthrosis |
New Lexington Clinic |
2006-03 | |
| NCT00003335 | COMPLETED | Graft Versus Host Disease; Leukemia; Lymphoma; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Diseases |
Case Comprehensive Cancer Center |
1998-01 | PHASE2 |
| NCT00005852 | TERMINATED | Chronic Myeloproliferative Disorders; Graft Versus Host Disease; Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes |
H. Lee Moffitt Cancer Center and Research Institute |
1996-06 | PHASE2 |
| NCT00411879 | COMPLETED | Heart Arrest |
University of Athens |
2006-06 | PHASE2 |
| NCT00290628 | TERMINATED | Chronic Myeloproliferative Disorders; Diamond-blackfan Anemia; Fanconi Anemia; Graft Versus Host Disease; Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Diseases |
Masonic Cancer Center, University of Minnesota |
1999-10 | |
| NCT00002565 | COMPLETED | Lymphoma |
M.D. Anderson Cancer Center |
1994-05-25 | PHASE3 |
| NCT01392833 | COMPLETED | IgA Nephropathy; Chronic Kidney Disease |
A. Manzoni Hospital |
1999-12 | PHASE3 |
| NCT00410657 | COMPLETED | Breast Cancer; Chronic Myeloproliferative Disorders; Gestational Trophoblastic Tumor; Graft Versus Host Disease; Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Diseases; Neuroblastoma; Ovarian Cancer; Testicular Germ Cell Tumor |
Fred Hutchinson Cancer Center |
2006-07 | PHASE2 |
| NCT00109993 | COMPLETED | Breast Cancer; Chronic Myeloproliferative Disorders; Gestational Trophoblastic Tumor; Graft Versus Host Disease; Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Diseases; Neuroblastoma; Ovarian Cancer; Testicular Germ Cell Tumor |
Case Comprehensive Cancer Center |
2005-01 | PHASE2 |
| NCT00185510 | COMPLETED | Dermatitis, Atopic |
LEO Pharma |
2005-03 | PHASE4 |
| NCT00004482 | COMPLETED | Myocarditis; Giant Cell Myocarditis |
Mayo Clinic |
1999-12 | PHASE2 |
| NCT00312520 | COMPLETED | Hemangiomas |
The Hospital for Sick Children |
2002-07 | PHASE3 |
| NCT00003187 | COMPLETED | Leukemia; Lymphoma; Myelodysplastic Syndromes |
Virginia Commonwealth University |
1995-05 | PHASE2; PHASE3 |
| NCT00023231 | COMPLETED | End-Stage Renal Disease |
National Institute of Allergy and Infectious Diseases (NIAID) |
2001-02 | |
| NCT00002718 | COMPLETED | Leukemia; Lymphoma; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Neoplasms |
Memorial Sloan Kettering Cancer Center |
1995-11 | PHASE2 |
| NCT00055653 | COMPLETED | Leukemia; Lymphoma; Myelodysplastic Syndromes; Myelodysplastic-Myeloproliferative Diseases |
Roswell Park Cancer Institute |
2003-01 | PHASE2 |
| NCT00002471 | COMPLETED | Leukemia; Lymphoma |
Memorial Sloan Kettering Cancer Center |
1990-02 | PHASE2 |
| NCT00037115 | WITHDRAWN | Demyelinating Disorders; Multiple Sclerosis; Optic Neuritis; Myelitis; Neuritis |
MidAmerica Neuroscience Research Foundation at Rowe Neurology Institute |
2002-05 | PHASE4 |
| NCT00006054 | TERMINATED | Immunologic Deficiency Syndromes; Chediak-Higashi Syndrome; Common Variable Immunodeficiency; Graft Versus Host Disease; X-Linked Lymphoproliferative Syndrome; Familial Erythrophagocytic Lymphohistiocytosis; Hemophagocytic Lymphohistiocytosis; X-linked Agammaglobulinemia; Wiskott-Aldrich Syndrome; Chronic Granulomatous Disease; X-linked Hyper IgM Syndrome; Severe Combined Immunodeficiency; Leukocyte Adhesion Deficiency Syndrome; Virus-Associated Hemophagocytic Syndrome |
Fairview University Medical Center |
2000-03 | |
| NCT00048165 | COMPLETED | Heart Transplantation |
Hoffmann-La Roche |
1999-08 | PHASE4 |
| NCT00005988 | COMPLETED | Graft Versus Host Disease; Leukemia; Lymphoma; Myelodysplastic Syndromes; Myeloma |
Dana-Farber Cancer Institute |
2000-02 | PHASE1 |
| NCT00003682 | TERMINATED | Prostate Cancer |
UNICANCER |
1998-10 | PHASE3 |
| NCT00006451 | WITHDRAWN | Graft Versus Host Disease; Leukemia; Lymphoma |
Masonic Cancer Center, University of Minnesota |
1996-04 | PHASE3 |
| NCT01177371 | COMPLETED | Accelerated Phase Chronic Myelogenous Leukemia; Adult Acute Lymphoblastic Leukemia in Remission; Adult Acute Megakaryoblastic Leukemia (M7); Adult Acute Monoblastic Leukemia (M5a); Adult Acute Monocytic Leukemia (M5b); Adult Acute Myeloblastic Leukemia With Maturation (M2); Adult Acute Myeloblastic Leukemia Without Maturation (M1); Adult Acute Myeloid Leukemia in Remission; Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities; Adult Acute Myeloid Leukemia With Del(5q); Adult Acute Myeloid Leukemia With Inv(16)(p13;q22); Adult Acute Myeloid Leukemia With T(15;17)(q22;q12); Adult Acute Myeloid Leukemia With T(16;16)(p13;q22); Adult Acute Myeloid Leukemia With T(8;21)(q22;q22); Adult Acute Myelomonocytic Leukemia (M4); Adult Acute Promyelocytic Leukemia (M3); Adult Erythroleukemia (M6a); Adult Nasal Type Extranodal NK/T-cell Lymphoma; Adult Pure Erythroid Leukemia (M6b); Anaplastic Large Cell Lymphoma; Angioimmunoblastic T-cell Lymphoma; Burkitt Lymphoma; Childhood Acute Erythroleukemia (M6); Childhood Acute Lymphoblastic Leukemia in Remission; Childhood Acute Megakaryocytic Leukemia (M7); Childhood Acute Monoblastic Leukemia (M5a); Childhood Acute Monocytic Leukemia (M5b); Childhood Acute Myeloblastic Leukemia With Maturation (M2); Childhood Acute Myeloblastic Leukemia Without Maturation (M1); Childhood Acute Myeloid Leukemia in Remission; Childhood Acute Myelomonocytic Leukemia (M4); Childhood Acute Promyelocytic Leukemia (M3); Childhood Chronic Myelogenous Leukemia; Childhood Myelodysplastic Syndromes; Chronic Phase Chronic Myelogenous Leukemia; Cutaneous B-cell Non-Hodgkin Lymphoma; De Novo Myelodysplastic Syndromes; Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue; Hepatosplenic T-cell Lymphoma; Intraocular Lymphoma; Nodal Marginal Zone B-cell Lymphoma; Peripheral T-Cell Lymphoma; Post-transplant Lymphoproliferative Disorder; Previously Treated Myelodysplastic Syndromes; Recurrent Adult Acute Lymphoblastic Leukemia; Recurrent Adult Acute Myeloid Leukemia; Recurrent Adult Burkitt Lymphoma; Recurrent Adult Diffuse Large Cell Lymphoma; Recurrent Adult Diffuse Mixed Cell Lymphoma; Recurrent Adult Diffuse Small Cleaved Cell Lymphoma; Recurrent Adult Grade III Lymphomatoid Granulomatosis; Recurrent Adult Hodgkin Lymphoma; Recurrent Adult Immunoblastic Large Cell Lymphoma; Recurrent Adult Lymphoblastic Lymphoma; Recurrent Adult Non-Hodgkin Lymphoma; Recurrent Adult T-cell Leukemia/Lymphoma; Recurrent Childhood Acute Lymphoblastic Leukemia; Recurrent Childhood Acute Myeloid Leukemia; Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma; Recurrent Grade 1 Follicular Lymphoma; Recurrent Grade 2 Follicular Lymphoma; Recurrent Grade 3 Follicular Lymphoma; Recurrent Mantle Cell Lymphoma; Recurrent Marginal Zone Lymphoma; Recurrent Mycosis Fungoides/Sezary Syndrome; Recurrent Small Lymphocytic Lymphoma; Refractory Multiple Myeloma; Relapsing Chronic Myelogenous Leukemia; Secondary Myelodysplastic Syndromes; Small Intestine Lymphoma; Splenic Marginal Zone Lymphoma; Testicular Lymphoma; Waldenstrom Macroglobulinemia |
Case Comprehensive Cancer Center |
1988-03 | PHASE2 |
| NCT00003661 | COMPLETED | Graft Versus Host Disease; Leukemia; Lymphoma; Myelodysplastic Syndromes; Neuroblastoma |
Roswell Park Cancer Institute |
1998-06 | PHASE2 |
| NCT00004785 | COMPLETED | Bronchopulmonary Dysplasia |
National Center for Research Resources (NCRR) |
1995-11 | PHASE3 |
| NCT01028313 | WITHDRAWN | Chronic Graft-Versus-Host Disease |
SCRI Development Innovations, LLC |
PHASE2 | |
| NCT00562835 | UNKNOWN | Acute Lung Injury; ARDS, Human |
Catholic University of the Sacred Heart |
2008-02 | PHASE2; PHASE3 |
| NCT00004255 | COMPLETED | Graft Versus Host Disease; Leukemia; Myelodysplastic Syndromes |
Chimeric Therapies |
2000-03 | PHASE2; PHASE3 |
| NCT00307645 | TERMINATED | ANCA Associated Systemic Vasculitis Including Wegener's; Granulomatosis and Microscopic Polyangiitis and; Renal Limited Vasculitis |
Assistance Publique - Hôpitaux de Paris |
2003-05 | PHASE3 |
| NCT00004645 | UNKNOWN | Acute Disseminated Encephalomyelitis; Devic's Syndrome; Marburg's Variant of Multiple Sclerosis; Balo's Concentric Sclerosis; Acute Transverse Myelitis |
National Institute of Neurological Disorders and Stroke (NINDS) |
1995-01 | PHASE3 |
| NCT00261820 | COMPLETED | Graft Rejection; Kidney Failure; Kidney Transplantation |
Wyeth is now a wholly owned subsidiary of Pfizer |
PHASE4 | |
| NCT00000741 | WITHDRAWN | Pneumonia, Pneumocystis Carinii; HIV Infections |
National Institute of Allergy and Infectious Diseases (NIAID) |
PHASE3 | |
| NCT00000579 | COMPLETED | Respiratory Distress Syndrome, Adult; Lung Diseases |
National Heart, Lung, and Blood Institute (NHLBI) |
1994-09 | PHASE3 |
| NCT00436761 | UNKNOWN | Unspecified Childhood Solid Tumor, Protocol Specific |
Milton S. Hershey Medical Center |
2004-05 | PHASE1 |
| NCT00431119 | COMPLETED | Bullous Pemphigoid |
University Hospital Muenster |
1997-10 | PHASE2 |
| NCT00008307 | UNKNOWN | Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes |
Herbert Irving Comprehensive Cancer Center |
1998-04 | PHASE2 |
| NCT00455286 | UNKNOWN | Primary Central Nervous System Lymphoma |
National Health Research Institutes, Taiwan |
2006-11 | PHASE2 |
| NCT00135967 | COMPLETED | Glomerulonephritis, Membranous |
Radboud University Medical Center |
2002-05 | PHASE2; PHASE3 |
| NCT00292760 | COMPLETED | Chronic Lymphocytic Leukaemia |
Royal Marsden NHS Foundation Trust |
PHASE2 | |
| NCT00017654 | UNKNOWN | Graft Versus Host Disease; Aplastic Anemia |
Northwestern Memorial Hospital |
2001-04 | |
| NCT00480298 | COMPLETED | Nasal Polyposis |
University Hospital, Ghent |
2002-11 | PHASE2 |
(data from https://clinicaltrials.gov, updated on 2026-07-30)
Check the
Methylprednisolone
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Mechanism and Biochemical Profile
Appendix RUO and cGMP Quality Standards
| Quality Dimension | RUO (Research Use Only) | cGMP (Current Good Manufacturing Practice) |
|---|---|---|
| Clinical Applicability | Prohibited in human clinical trials or medical diagnostics. | Mandatory for human clinical trials (Phase I–III) and therapies. |
| Regulatory Status | Non-regulated grade; exempt from drug manufacturing laws. | Legally enforced by health authorities (e.g., FDA, EMA, NMPA). |
| Facility Environment | Unclassified analytical or research laboratories. | Validated Cleanrooms (ISO Class 5–8) with continuous monitoring. |
| Quality Control | Basic purity and activity testing. | Rigorous safety release testing (Sterility, Endotoxin, Mycoplasma). |
| Process Validation | Basic equipment calibration; no process validation required. | Full qualification (IQ/OQ/PQ) and complete batch records. |
| Quality Assurance | Vendor self-declared without required formal QMS. | Mandatory QA/QC unit, Change Control, CAPA, and vendor audits. |
| Regulatory Impact | High risk of IND rejection if used as a critical raw material. | Required for IND/NDA filings, supported by Drug Master Files (DMF). |
Footnotes
Regulatory Note: Governed by FDA (21 CFR Parts 210/211/312), EMA (EudraLex Vol 4), ICH Guidelines (E6/Q7/Q9/Q10), and compendial standards (USP <71>/<85>/<1043>).
Note: Technical data last updated: Sep 1, 2026.