Leucovorin calcium pentahydrate has been evaluated across numerous clinical trials spanning early phase through Phase 4, with recruitment statuses including active, recruiting, and completed. Sponsored by major sponsors such as the National Cancer Institute, academic medical centers, and specialized research foundations, these studies investigate solid tumors, hematologic malignancies, and non-oncologic indications like autism spectrum and language disorders. Overall, these trials assess leucovorin to potentiate fluoropyrimidines, rescue methotrexate toxicity, or serve as a targeted intervention for neurological and metabolic conditions.
| NCT Number | Recruitment | Conditions | Sponsor/Collaborators | Start Date | Phases |
|---|---|---|---|---|---|
| NCT06365008 | NOT_YET_RECRUITING | Unresectable/Metastatic Gastric Cancer |
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University |
2026-06 | PHASE2 |
| NCT03959085 | RECRUITING | B Acute Lymphoblastic Leukemia; B Lymphoblastic Lymphoma; Central Nervous System Leukemia; Mixed Phenotype Acute Leukemia; Testicular Leukemia |
Children's Oncology Group |
2019-10-31 | PHASE3 |
| NCT06780111 | RECRUITING | Esophageal Squamous Cell Carcinoma |
Merck Sharp & Dohme LLC |
2025-07-30 | PHASE1; PHASE2 |
| NCT03801876 | ACTIVE_NOT_RECRUITING | Clinical Stage I Esophageal Adenocarcinoma AJCC v8; Clinical Stage I Esophageal Squamous Cell Carcinoma AJCC v8; Clinical Stage I Gastroesophageal Junction Adenocarcinoma AJCC v8; Clinical Stage II Esophageal Adenocarcinoma AJCC v8; Clinical Stage II Esophageal Squamous Cell Carcinoma AJCC v8; Clinical Stage II Gastroesophageal Junction Adenocarcinoma AJCC v8; Clinical Stage III Esophageal Adenocarcinoma AJCC v8; Clinical Stage III Esophageal Squamous Cell Carcinoma AJCC v8; Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8; Clinical Stage IVA Esophageal Adenocarcinoma AJCC v8; Clinical Stage IVA Esophageal Squamous Cell Carcinoma AJCC v8; Clinical Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8; Thoracic Esophagus Squamous Cell Carcinoma |
NRG Oncology |
2019-06-26 | PHASE3 |
| NCT07636564 | NOT_YET_RECRUITING | Acute Leukemia of Ambiguous Lineage; B Acute Lymphoblastic Leukemia; B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative; T Acute Lymphoblastic Leukemia |
SWOG Cancer Research Network |
2026-10-14 | PHASE2 |
| NCT07271355 | NOT_YET_RECRUITING | Metastatic Appendix Carcinoma; Metastatic Colorectal Carcinoma; Metastatic Malignant Neoplasm in the Peritoneum; Stage IV Appendix Carcinoma AJCC v8; Stage IVC Colorectal Cancer AJCC v8; Unresectable Colorectal Carcinoma |
City of Hope Medical Center |
2026-10-01 | PHASE3 |
| NCT06988852 | RECRUITING | Colorectal Liver Metastasis (CRLM) |
Tongji Hospital |
2023-05-01 | PHASE2 |
| NCT00004317 | RECRUITING | Toxoplasmosis |
National Institute of Allergy and Infectious Diseases (NIAID) |
2000-07 | PHASE4 |
| NCT06958328 | RECRUITING | Locally Advanced Unresectable Pancreatic Ductal Adenocarcinoma; Stage II Pancreatic Cancer AJCC v8; Stage III Pancreatic Cancer AJCC v8; Stage IV Pancreatic Cancer AJCC v8 |
NRG Oncology |
2025-08-21 | PHASE3 |
| NCT06628310 | ACTIVE_NOT_RECRUITING | Locally Advanced Unresectable or Metastatic Gastric Adenocarcinoma; Gastroesophageal Junction Adenocarcinoma; Esophageal Adenocarcinoma |
AbbVie |
2024-12-13 | PHASE2 |
| NCT07662031 | NOT_YET_RECRUITING | Colorectal Cancer; Metastatic Colorectal Cancer |
Washington University School of Medicine |
2026-08-31 | PHASE2 |
| NCT05564377 | RECRUITING | Advanced Malignant Solid Neoplasm; Anatomic Stage III Breast Cancer AJCC v8; Anatomic Stage IV Breast Cancer AJCC v8; Locally Advanced Malignant Solid Neoplasm; Malignant Female Reproductive System Neoplasm; Metastatic HER2-Negative Breast Carcinoma; Metastatic Malignant Solid Neoplasm; Recurrent Endometrial Carcinoma; Recurrent Fallopian Tube Carcinoma; Recurrent Malignant Female Reproductive System Neoplasm; Recurrent Malignant Solid Neoplasm; Recurrent Ovarian Carcinoma; Recurrent Primary Peritoneal Carcinoma; Unresectable HER2-Negative Breast Carcinoma; Unresectable Malignant Solid Neoplasm |
National Cancer Institute (NCI) |
2023-04-07 | PHASE2 |
| NCT05719558 | RECRUITING | Advanced Solid Tumors |
Astellas Pharma Global Development, Inc. |
2023-03-13 | PHASE1 |
| NCT07183865 | RECRUITING | Locally Recurrent Rectal Cancer |
Fudan University |
2025-03-09 | PHASE2 |
| NCT07432295 | RECRUITING | Solid Tumor; Advanced Cancer; Metastatic Cancer; Gastric Cancer; Gastroesophageal Junction Carcinoma; Esophageal Adenocarcinoma |
I-Mab Biopharma US Limited |
2026-02-11 | PHASE2 |
| NCT05067283 | RECRUITING | Advanced Solid Tumors |
Merck Sharp & Dohme LLC |
2021-12-17 | PHASE1 |
| NCT06607185 | ACTIVE_NOT_RECRUITING | Pancreatic Ductal Adenocarcinoma; Non-small Cell Lung Cancer; Colorectal Cancer; Advanced Solid Tumor; Metastatic Solid Tumor |
Eli Lilly and Company |
2024-10-21 | PHASE1 |
| NCT07283367 | RECRUITING | CRC |
Hansoh BioMedical R&D Company |
2025-12-22 | PHASE1; PHASE2 |
| NCT06998940 | RECRUITING | Locally Advanced Pancreatic Adenocarcinoma; Metastatic Pancreatic Adenocarcinoma; Stage III Pancreatic Cancer AJCC v8; Stage IV Pancreatic Cancer AJCC v8; Unresectable Pancreatic Adenocarcinoma |
SWOG Cancer Research Network |
2026-05-13 | PHASE3 |
| NCT06428409 | RECRUITING | Colorectal Cancer; Pancreatic Ductal Adenocarcinoma; Biliary Tract Cancer |
Merck Sharp & Dohme LLC |
2024-06-20 | PHASE1; PHASE2 |
| NCT03899155 | RECRUITING | Cancer |
Bristol-Myers Squibb |
2019-08-09 | PHASE2 |
| NCT07431281 | RECRUITING | Gastric Cancer; Gastroesophageal Junction Adenocarcinoma; Esophageal Cancer |
AstraZeneca |
2026-02-03 | PHASE3 |
| NCT07028424 | NOT_YET_RECRUITING | PDAC - Pancreatic Ductal Adenocarcinoma |
GERCOR - Multidisciplinary Oncology Cooperative Group |
2025-07 | PHASE2 |
| NCT07621497 | NOT_YET_RECRUITING | Metastatic Colorectal Cancer (CRC) |
Sun Yat-sen University |
2026-06-01 | PHASE2 |
| NCT06586515 | RECRUITING | Pancreatic Ductal Adenocarcinoma; Non-small Cell Lung Cancer; Colorectal Cancer |
Eli Lilly and Company |
2024-09-12 | PHASE1 |
| NCT07803783 | NOT_YET_RECRUITING | Metastatic Pancreatic Cancer; Pancreatic Ductal Adenocarcinoma (PDAC) |
MediLink Therapeutics (Suzhou) Co., Ltd. |
2026-10 | PHASE3 |
| NCT07790445 | NOT_YET_RECRUITING | Malignant Biliary Tract Tumors |
Zhai Wenlong |
2026-07-30 | PHASE4 |
| NCT07391566 | NOT_YET_RECRUITING | Metastatic Colorectal Cancer (mCRC) |
Luye Pharma Group Ltd. |
2026-03-31 | PHASE1; PHASE2 |
| NCT04340141 | ACTIVE_NOT_RECRUITING | Pancreatic Adenosquamous Carcinoma; Resectable Pancreatic Adenocarcinoma; Stage I Pancreatic Cancer AJCC v8; Stage II Pancreatic Cancer AJCC v8; Stage III Pancreatic Cancer AJCC v8 |
Alliance for Clinical Trials in Oncology |
2020-10-13 | PHASE3 |
| NCT06963502 | NOT_YET_RECRUITING | Advanced Solid Tumors; Colorectal Cancer; Non-Small Cell Lung Cancer |
Jiangsu Hansoh Pharmaceutical Co., Ltd. |
2025-05-30 | PHASE1 |
| NCT06662786 | RECRUITING | Colorectal Neoplasms |
Janssen Research & Development, LLC |
2024-10-18 | PHASE3 |
| NCT07737600 | NOT_YET_RECRUITING | Advanced Colorectal Cancer |
Lepu Biopharma Co., Ltd. |
2026-08 | PHASE1; PHASE2 |
| NCT06887218 | RECRUITING | Metastatic Colorectal Cancer (CRC) |
The Methodist Hospital Research Institute |
2025-05-08 | PHASE2 |
| NCT05677490 | RECRUITING | Advanced Esophageal Adenocarcinoma; Advanced Gastric Adenocarcinoma; Advanced Gastroesophageal Junction Adenocarcinoma; Clinical Stage III Esophageal Adenocarcinoma AJCC v8; Clinical Stage III Gastric Cancer AJCC v8; Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8; Clinical Stage IV Esophageal Adenocarcinoma AJCC v8; Clinical Stage IV Gastric Cancer AJCC v8; Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8; Metastatic Esophageal Adenocarcinoma; Metastatic Gastric Adenocarcinoma; Metastatic Gastroesophageal Junction Adenocarcinoma; Unresectable Esophageal Adenocarcinoma; Unresectable Gastric Adenocarcinoma; Unresectable Gastroesophageal Junction Adenocarcinoma |
Alliance for Clinical Trials in Oncology |
2023-01-31 | PHASE3 |
| NCT02885753 | RECRUITING | Colorectal Neoplasms |
Federation Francophone de Cancerologie Digestive |
2016-12 | PHASE3 |
| NCT05647122 | ACTIVE_NOT_RECRUITING | Advanced Solid Tumours; Carcinoma Non-small Cell Lung; Head and Neck Neoplasms; Colorectal Neoplasms |
AstraZeneca |
2022-12-21 | PHASE1 |
| NCT07290985 | RECRUITING | Gastroesophageal Adenocarcinoma |
American Association for Cancer Research |
2026-07-20 | PHASE2 |
| NCT05365581 | RECRUITING | Gastric Adenocarcinoma; Gastroesophageal Junction (GEJ) Adenocarcinoma; Pancreatic Adenocarcinoma |
Astellas Pharma Global Development, Inc. |
2022-06-07 | PHASE1 |
| NCT06733038 | RECRUITING | Colorectal Cancer |
Gruppo Oncologico del Nord-Ovest |
2024-11-15 | PHASE3 |
| NCT04248452 | ACTIVE_NOT_RECRUITING | Clinical Stage IV Esophageal Adenocarcinoma AJCC v8; Clinical Stage IV Gastric Cancer AJCC v8; Clinical Stage IVA Esophageal Adenocarcinoma AJCC v8; Clinical Stage IVA Gastric Cancer AJCC v8; Clinical Stage IVB Esophageal Adenocarcinoma AJCC v8; Clinical Stage IVB Gastric Cancer AJCC v8; Metastatic Esophageal Adenocarcinoma; Metastatic Gastric Adenocarcinoma; Oligometastatic Esophageal Adenocarcinoma; Oligometastatic Gastric Adenocarcinoma; Pathologic Stage IV Esophageal Adenocarcinoma AJCC v8; Pathologic Stage IV Gastric Cancer AJCC v8; Pathologic Stage IVA Esophageal Adenocarcinoma AJCC v8; Pathologic Stage IVB Esophageal Adenocarcinoma AJCC v8 |
ECOG-ACRIN Cancer Research Group |
2020-05-26 | PHASE3 |
| NCT06247787 | RECRUITING | Recurrent Childhood Acute Myeloid Leukemia; Recurrent Childhood Myelodysplastic Syndrome; Recurrent Juvenile Myelomonocytic Leukemia; Refractory Childhood Acute Myeloid Leukemia; Refractory Childhood Myelodysplastic Syndrome; Refractory Juvenile Myelomonocytic Leukemia |
Children's Oncology Group |
2025-02-04 | PHASE1 |
| NCT06381154 | ACTIVE_NOT_RECRUITING | Locally Advanced Pancreatic Adenocarcinoma; Metastatic Pancreatic Adenocarcinoma; Stage II Pancreatic Cancer AJCC v8; Stage III Pancreatic Cancer AJCC v8; Stage IV Pancreatic Cancer AJCC v8; Unresectable Pancreatic Adenocarcinoma |
Mayo Clinic |
2024-12-06 | PHASE2 |
| NCT06109467 | ACTIVE_NOT_RECRUITING | GastroEsophageal Cancer; Gastric Cancer |
H. Lee Moffitt Cancer Center and Research Institute |
2024-01-12 | PHASE2 |
| NCT04901741 | NOT_YET_RECRUITING | Metastatic Pancreatic Cancer |
TME Pharma AG |
2026-01 | PHASE2 |
| NCT07094893 | NOT_YET_RECRUITING | Colorectal Cancer |
Gruppo Oncologico del Nord-Ovest |
2026-09-15 | PHASE4 |
| NCT07733180 | NOT_YET_RECRUITING | Advanced Esophageal Squamous Cell Carcinoma; Metastatic Esophageal Squamous Cell Carcinoma |
BeOne Medicines |
2026-08-31 | PHASE2 |
| NCT06757244 | RECRUITING | Pancreas Neoplasms |
Hopital Foch |
2025-02-18 | PHASE2 |
| NCT07214298 | RECRUITING | Metastatic Pancreatic Ductal Adenocarcinoma; Stage IV Pancreatic Cancer AJCC v8 |
Roswell Park Cancer Institute |
2026-02-16 | PHASE1; PHASE2 |
| NCT06771622 | ACTIVE_NOT_RECRUITING | Solid Cancer |
FBD Biologics Limited |
2025-03-13 | PHASE1; PHASE2 |
| NCT07642661 | RECRUITING | Autism Spectrum Disorder |
Prof. Adi Aran |
2026-06-23 | PHASE2 |
| NCT07314385 | NOT_YET_RECRUITING | Pancreatic Adenocarcinoma Metastatic; Liver Metastasis |
National Taiwan University Hospital |
2026-01-01 | PHASE1 |
| NCT05253651 | RECRUITING | Colorectal Neoplasms |
Seagen, a wholly owned subsidiary of Pfizer |
2022-10-24 | PHASE3 |
| NCT07705919 | NOT_YET_RECRUITING | Borderline Resectable Pancreatic Ductal Adenocarcinoma |
Ohio State University Comprehensive Cancer Center |
2026-09-01 | PHASE1; PHASE2 |
| NCT05358704 | SUSPENDED | Cancer of Rectum |
Rutgers, The State University of New Jersey |
2022-05-13 | PHASE2 |
| NCT06750094 | RECRUITING | Colorectal Neoplasms |
Janssen Research & Development, LLC |
2024-12-12 | PHASE3 |
| NCT07340151 | RECRUITING | Adenocarcinoma of the Pancreas |
The University of Texas Health Science Center at San Antonio |
2026-03-02 | |
| NCT06780787 | RECRUITING | Rectal Adenocarcinoma; Stage IIA Rectal Cancer AJCC v8; Stage III Rectal Cancer AJCC v8 |
City of Hope Medical Center |
2025-05-20 | PHASE2 |
| NCT05062889 | SUSPENDED | Stage II Colon Cancer; Stage III Colon Cancer; HER2-positive Colon Cancer; RAS Wild-type Colon Cancer |
Gruppo Oncologico del Nord-Ovest |
2023-05-17 | PHASE2 |
| NCT07474727 | RECRUITING | Colorectal Cancer |
Multitude Therapeutics Inc. |
2026-04-29 | PHASE2 |
| NCT03914625 | ACTIVE_NOT_RECRUITING | B Acute Lymphoblastic Leukemia; B Lymphoblastic Lymphoma; Down Syndrome |
National Cancer Institute (NCI) |
2019-07-03 | PHASE3 |
| NCT07337421 | RECRUITING | Hepatocellular Carcinoma (HCC) |
Northern Jiangsu People's Hospital |
2025-09-01 | PHASE2 |
| NCT05891171 | ACTIVE_NOT_RECRUITING | Advanced Cancer; Advanced Malignancies; Bladder Cancer; Cervical Cancer; Esophageal Cancer; Gastric Cancer; Gastroesophageal-junction Cancer (GEJ); Head and Neck Squamous Cell Carcinoma (HNSCC); Non-Small Cell Lung Cancer (NSCLC); Ovarian Cancer; Renal Cell Carcinoma (RCC); Triple Negative Breast Cancer (TNBC) |
Arcus Biosciences, Inc. |
2023-10-13 | PHASE1 |
| NCT07353827 | NOT_YET_RECRUITING | Intrahepatic Cholangiocarcinoma (Icc); Hepatic Arterial Infusion Chemotherapy |
Sun Yat-sen University |
2026-02-01 | PHASE2 |
| NCT07363408 | NOT_YET_RECRUITING | Advanced Microsatellite Stable Colorectal Carcinoma; Metastatic Microsatellite Stable Colorectal Carcinoma; Stage III Colorectal Cancer AJCC v8; Stage IV Colorectal Cancer AJCC v8 |
City of Hope Medical Center |
2026-12-01 | PHASE1 |
| NCT03977233 | RECRUITING | Pancreatic Ductal Adenocarcinoma (PDAC); Cancer of Pancreas; Pancreatic Cancer, Adult; Pancreas Adenocarcinoma; Pancreatic Neoplasms; Pancreatic Cancer Non-resectable; Pancreatic Cancer Resectable |
UNC Lineberger Comprehensive Cancer Center |
2019-06-12 | PHASE2 |
| NCT03505320 | ACTIVE_NOT_RECRUITING | Pharmacokinetics of Zolbetuximab; Gastric Cancer; Gastro-esophageal Junction (GEJ) Cancer; Pharmacokinetics of Oxaliplatin; Pharmacokinetics of Fluorouracil Bolus (5-FU) |
Astellas Pharma Global Development, Inc. |
2018-06-29 | PHASE2 |
| NCT06792695 | RECRUITING | Metastatic Colorectal Cancer |
AstraZeneca |
2025-03-12 | PHASE2 |
| NCT06598007 | RECRUITING | Solid Tumor, Adult; Colorectal Cancer; Pancreatic Ductal Adenocarcinoma |
Crossignal Therapeutics, Inc. |
2024-09-20 | PHASE1; PHASE2 |
| NCT05627635 | ACTIVE_NOT_RECRUITING | Metastatic Colon Adenocarcinoma; Metastatic Colorectal Adenocarcinoma; Metastatic Microsatellite Stable Colorectal Carcinoma; Metastatic Rectal Adenocarcinoma; Stage IV Colon Cancer AJCC v8; Stage IV Colorectal Cancer AJCC v8; Stage IV Rectal Cancer AJCC v8 |
City of Hope Medical Center |
2023-05-03 | PHASE1; PHASE2 |
| NCT06576037 | RECRUITING | Solid Tumor |
M.D. Anderson Cancer Center |
2024-10-31 | PHASE1 |
| NCT04919226 | ACTIVE_NOT_RECRUITING | Neuroendocrine Tumors |
ITM Solucin GmbH |
2021-12-21 | PHASE3 |
| NCT06078709 | RECRUITING | Clinical Stage I Esophageal Adenocarcinoma AJCC v8; Clinical Stage I Gastroesophageal Junction Adenocarcinoma AJCC v8; Clinical Stage II Esophageal Adenocarcinoma AJCC v8; Clinical Stage II Gastroesophageal Junction Adenocarcinoma AJCC v8; Clinical Stage III Esophageal Adenocarcinoma AJCC v8; Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8 |
Mayo Clinic |
2023-11-20 | PHASE2 |
| NCT05802056 | ACTIVE_NOT_RECRUITING | Clinical Stage IV Gastric Cancer AJCC v8; Gastric Adenocarcinoma; Gastroesophageal Junction Adenocarcinoma; Metastatic Gastric Carcinoma; Metastatic Malignant Neoplasm in the Peritoneum |
Mayo Clinic |
2023-11-29 | PHASE1 |
| NCT06901531 | RECRUITING | Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or Cancer; Locally Advanced Unresectable Gastric Adenocarcinoma or Cancer; Metastatic Gastric Adenocarcinoma or Cancer; Metastatic Gastroesophageal Junction (GEJ) Adenocarcinoma |
Astellas Pharma Global Development, Inc. |
2025-05-22 | PHASE3 |
| NCT06860477 | RECRUITING | Intrahepatic Cholangiocellular Carcinoma |
Fudan University |
2025-03-18 | PHASE2 |
| NCT06383078 | NOT_YET_RECRUITING | Efficacy and Safety |
The First Affiliated Hospital with Nanjing Medical University |
2024-04-20 | PHASE2 |
| NCT06821997 | RECRUITING | Borderline Resectable Pancreatic Ductal Adenocarcinoma |
Roswell Park Cancer Institute |
2026-03-02 | PHASE2 |
| NCT05141721 | ACTIVE_NOT_RECRUITING | Colorectal Neoplasms |
Seattle Project Corporation |
2022-02-12 | PHASE2; PHASE3 |
| NCT04205968 | RECRUITING | Metastatic Small Intestinal Adenocarcinoma; Stage III Small Intestinal Adenocarcinoma AJCC v8; Stage IIIA Small Intestinal Adenocarcinoma AJCC v8; Stage IIIB Small Intestinal Adenocarcinoma AJCC v8; Stage IV Small Intestinal Adenocarcinoma AJCC v8 |
SWOG Cancer Research Network |
2020-06-01 | PHASE2 |
| NCT03109288 | RECRUITING | Multiple Sclerosis |
National Institute of Allergy and Infectious Diseases (NIAID) |
2017-08-11 | PHASE1; PHASE2 |
| NCT05329766 | ACTIVE_NOT_RECRUITING | Gastrointestinal Tract Malignancies |
Arcus Biosciences, Inc. |
2022-06-10 | PHASE2 |
| NCT04927780 | ACTIVE_NOT_RECRUITING | Pancreatic Cancer; Pancreatic Ductal Adenocarcinoma; Resectable Pancreatic Adenocarcinoma |
Erasmus Medical Center |
2021-09-07 | PHASE3 |
| NCT01924819 | ACTIVE_NOT_RECRUITING | Gastric Cancer |
Australasian Gastro-Intestinal Trials Group |
2009-09 | PHASE2; PHASE3 |
| NCT07025174 | RECRUITING | Bile Duct Carcinoma; Gall Bladder Cancer; Biliary Tract Cancer; Cholangiocarcinoma |
First Affiliated Hospital of Zhejiang University |
2025-06-01 | PHASE2 |
| NCT02981628 | ACTIVE_NOT_RECRUITING | Recurrent B Acute Lymphoblastic Leukemia; Recurrent B Lymphoblastic Lymphoma; Refractory B Acute Lymphoblastic Leukemia; Refractory B Lymphoblastic Lymphoma |
Children's Oncology Group |
2017-06-19 | PHASE2 |
| NCT06696768 | RECRUITING | Metastatic Colorectal Adenocarcinoma; Stage III Colorectal Cancer AJCC v8; Stage IV Colorectal Cancer AJCC v8; Unresectable Colorectal Adenocarcinoma |
National Cancer Institute (NCI) |
2025-06-23 | PHASE1 |
| NCT05796401 | RECRUITING | Psychosis |
Centre Hospitalier St Anne |
2023-12-15 | PHASE3 |
| NCT05688215 | RECRUITING | Borderline Resectable Pancreatic Adenocarcinoma; Locally Advanced Pancreatic Ductal Adenocarcinoma |
Jonsson Comprehensive Cancer Center |
2023-03-07 | PHASE1; PHASE2 |
| NCT07283848 | WITHDRAWN | Adenocarcinoma Stomach; Adenocarcinoma Gastroesophageal Junction |
Massachusetts General Hospital |
2026-02-01 | PHASE2 |
| NCT06219941 | RECRUITING | Gastric Cancer; Gastroesophageal Junction Cancer; Biliary Tract Cancer; Pancreatic Ductal Adenocarcinoma |
AstraZeneca |
2023-12-13 | PHASE2 |
| NCT06825624 | RECRUITING | Metastatic Colorectal Cancer (CRC) |
Hansoh BioMedical R&D Company |
2024-10-03 | PHASE1 |
| NCT06447662 | ACTIVE_NOT_RECRUITING | Carcinoma, Pancreatic Ductal; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung |
Pfizer |
2024-06-27 | PHASE1 |
| NCT05564403 | ACTIVE_NOT_RECRUITING | Advanced Biliary Tract Carcinoma; Advanced Gallbladder Carcinoma; Advanced Intrahepatic Cholangiocarcinoma; Recurrent Biliary Tract Carcinoma; Recurrent Gallbladder Carcinoma; Recurrent Intrahepatic Cholangiocarcinoma; Stage III Distal Bile Duct Cancer AJCC v8; Stage III Gallbladder Cancer AJCC v8; Stage III Hilar Cholangiocarcinoma AJCC v8; Stage III Intrahepatic Cholangiocarcinoma AJCC v8; Stage IV Distal Bile Duct Cancer AJCC v8; Stage IV Gallbladder Cancer AJCC v8; Stage IV Hilar Cholangiocarcinoma AJCC v8; Stage IV Intrahepatic Cholangiocarcinoma AJCC v8; Unresectable Biliary Tract Carcinoma; Unresectable Gallbladder Carcinoma; Unresectable Intrahepatic Cholangiocarcinoma |
National Cancer Institute (NCI) |
2024-02-09 | PHASE2 |
| NCT04703101 | RECRUITING | Locally Advanced Rectal Carcinoma; Rectal Adenocarcinoma; Stage II Rectal Cancer AJCC v8; Stage IIA Rectal Cancer AJCC v8; Stage IIB Rectal Cancer AJCC v8; Stage IIC Rectal Cancer AJCC v8; Stage III Rectal Cancer AJCC v8; Stage IIIA Rectal Cancer AJCC v8; Stage IIIB Rectal Cancer AJCC v8; Stage IIIC Rectal Cancer AJCC v8 |
Jonsson Comprehensive Cancer Center |
2021-02-11 | PHASE1 |
| NCT04246684 | ACTIVE_NOT_RECRUITING | Rectal Cancer Stage III |
Prof. Dr. med. Claus Rödel |
2020-11-05 | PHASE3 |
| NCT03800693 | RECRUITING | Malignant Digestive System Neoplasm |
Emory University |
2019-03-14 | PHASE2 |
| NCT03203525 | TERMINATED | Advanced Malignant Neoplasm; Colorectal Carcinoma Metastatic in the Liver; Metastatic Malignant Neoplasm in the Liver; Refractory Malignant Neoplasm |
M.D. Anderson Cancer Center |
2020-06-23 | PHASE1 |
| NCT07277270 | RECRUITING | Neoplasms |
GlaxoSmithKline |
2025-12-03 | PHASE1 |
| NCT03007147 | ACTIVE_NOT_RECRUITING | Acute Lymphoblastic Leukemia; B Acute Lymphoblastic Leukemia; Mixed Phenotype Acute Leukemia; T Acute Lymphoblastic Leukemia |
Children's Oncology Group |
2017-08-08 | PHASE3 |
| NCT06625320 | ACTIVE_NOT_RECRUITING | Pancreatic Cancer; PDAC; PDAC - Pancreatic Ductal Adenocarcinoma |
Revolution Medicines, Inc. |
2024-10-16 | PHASE3 |
| NCT06704724 | TERMINATED | Carcinoma, Pancreatic Ductal; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung |
Pfizer |
2024-12-10 | PHASE1 |
| NCT06370754 | NOT_YET_RECRUITING | Pancreatic Cancer |
Fudan University |
2024-04-30 | PHASE1; PHASE2 |
| NCT04689347 | RECRUITING | Metastatic Colorectal Cancer |
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano |
2021-01-01 | PHASE1; PHASE2 |
| NCT04481204 | WITHDRAWN | Borderline Resectable Pancreatic Adenocarcinoma; Locally Advanced Pancreatic Ductal Adenocarcinoma; Resectable Pancreatic Ductal Adenocarcinoma |
M.D. Anderson Cancer Center |
2023-04-18 | PHASE2 |
| NCT06993025 | NOT_YET_RECRUITING | Biliary Tract Cancer |
Tianjin Medical University Cancer Institute and Hospital |
2025-05-25 | PHASE2 |
| NCT02723994 | COMPLETED | Leukemia |
Incyte Corporation |
2016-09-30 | PHASE2 |
| NCT04233866 | ACTIVE_NOT_RECRUITING | Metastatic Pancreatic Adenocarcinoma; Stage IV Pancreatic Cancer AJCC v8 |
ECOG-ACRIN Cancer Research Group |
2020-08-26 | PHASE2 |
| NCT06490536 | RECRUITING | Colon Cancer Stage II; Colon Cancer Stage III |
IFOM ETS - The AIRC Institute of Molecular Oncology |
2024-10-22 | PHASE3 |
| NCT06011772 | ACTIVE_NOT_RECRUITING | Colo-rectal Cancer |
Roswell Park Cancer Institute |
2023-12-18 | EARLY_PHASE1 |
| NCT06184698 | RECRUITING | Colorectal Cancer |
Hebei Medical University Fourth Hospital |
2024-01-01 | PHASE2 |
| NCT05836584 | ACTIVE_NOT_RECRUITING | Clinical Stage I Gastric Cancer AJCC v8; Clinical Stage I Gastroesophageal Junction Adenocarcinoma AJCC v8; Clinical Stage II Gastric Cancer AJCC v8; Clinical Stage II Gastroesophageal Junction Adenocarcinoma AJCC v8; Clinical Stage III Gastric Cancer AJCC v8; Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8; Clinical Stage IVA Gastric Cancer AJCC v8; Clinical Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8; Gastric Adenocarcinoma; Gastroesophageal Junction Adenocarcinoma |
National Cancer Institute (NCI) |
2023-12-06 | PHASE2 |
| NCT05630183 | COMPLETED | Metastatic Pancreatic Ductal Adenocarcinoma |
Agenus Inc. |
2023-03-27 | PHASE2 |
| NCT05296005 | WITHDRAWN | Clinical Stage I Gastric Cancer AJCC v8; Clinical Stage II Gastric Cancer AJCC v8; Clinical Stage IIA Gastric Cancer AJCC v8; Clinical Stage IIB Gastric Cancer AJCC v8; Clinical Stage IIB Gastroesophageal Junction Adenocarcinoma AJCC v8; Clinical Stage III Gastric Cancer AJCC v8; Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8; Clinical Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8; Gastric Adenocarcinoma; Pathologic Stage IB Gastric Cancer AJCC v8; Pathologic Stage IC Gastroesophageal Junction Adenocarcinoma AJCC v8; Pathologic Stage II Gastric Cancer AJCC v8; Pathologic Stage II Gastroesophageal Junction Adenocarcinoma AJCC v8; Pathologic Stage IIA Gastric Cancer AJCC v8; Pathologic Stage IIA Gastroesophageal Junction Adenocarcinoma AJCC v8; Pathologic Stage IIB Gastric Cancer AJCC v8; Pathologic Stage IIB Gastroesophageal Junction Adenocarcinoma AJCC v8; Pathologic Stage III Gastric Cancer AJCC v8; Pathologic Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8; Pathologic Stage IIIA Gastric Cancer AJCC v8; Pathologic Stage IIIA Gastroesophageal Junction Adenocarcinoma AJCC v8; Pathologic Stage IIIB Gastric Cancer AJCC v8; Pathologic Stage IIIB Gastroesophageal Junction Adenocarcinoma AJCC v8; Pathologic Stage IIIC Gastric Cancer AJCC v8; Pathologic Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8 |
Ohio State University Comprehensive Cancer Center |
2025-12-31 | PHASE1 |
| NCT06176885 | RECRUITING | Colorectal Cancer |
yue junhan |
2023-12-20 | PHASE2 |
| NCT04821284 | ACTIVE_NOT_RECRUITING | Locally Advanced Pancreatic Ductal Adenocarcinoma; Metastatic Pancreatic Ductal Adenocarcinoma; Stage II Pancreatic Cancer AJCC v8; Stage IIA Pancreatic Cancer AJCC v8; Stage IIB Pancreatic Cancer AJCC v8; Stage III Pancreatic Cancer AJCC v8; Stage IV Pancreatic Cancer AJCC v8; Unresectable Pancreatic Ductal Adenocarcinoma |
Flemming Forsberg |
2021-12-06 | PHASE1; PHASE2 |
| NCT04390399 | ACTIVE_NOT_RECRUITING | Pancreatic Cancer |
ImmunityBio, Inc. |
2020-07-21 | PHASE2 |
| NCT03281369 | TERMINATED | Gastric Adenocarcinoma or Gastroesophageal Junction Adenocarcinoma or Esophageal Carcinoma |
Hoffmann-La Roche |
2017-10-13 | PHASE1; PHASE2 |
| NCT03929666 | COMPLETED | HER2-expressing Gastrointestinal Cancers, Including Gastroesophageal Adenocarcinoma, Biliary Tract Cancer, and Colorectal Cancer |
Jazz Pharmaceuticals |
2019-08-29 | PHASE2 |
| NCT04961970 | UNKNOWN | Intrahepatic Cholangiocarcinoma |
Shi Ming |
2021-07-09 | PHASE3 |
| NCT05378919 | RECRUITING | Neoadjuvant Therapy in Rectal Cancer, Radiotherapy, FOLFOX |
Lithuanian University of Health Sciences |
2015-06-01 | PHASE2 |
| NCT05859750 | RECRUITING | Pancreatic Cancer |
Akeso |
2023-05-25 | PHASE2 |
| NCT04141995 | TERMINATED | Pancreas Cancer; Adenocarcinoma of the Pancreas |
University of Nebraska |
2021-02-12 | PHASE2 |
| NCT06225999 | COMPLETED | Metastatic Adenocarcinoma of the Pancreas |
Institut de Recherches Internationales Servier |
2024-04-25 | PHASE2 |
| NCT04363801 | TERMINATED | Gastric Cancer; Gastric Adenocarcinoma; GastroEsophageal Cancer |
Leap Therapeutics, Inc. |
2020-07-29 | PHASE2 |
| NCT00059930 | COMPLETED | Colorectal Cancer; Metastatic Cancer |
Memorial Sloan Kettering Cancer Center |
2003-01 | PHASE1 |
| NCT04535401 | ACTIVE_NOT_RECRUITING | Advanced Colorectal Carcinoma; Advanced Digestive System Carcinoma; Advanced Gastric Carcinoma; Advanced Gastroesophageal Junction Adenocarcinoma; Clinical Stage III Gastric Cancer AJCC v8; Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8; Clinical Stage IV Gastric Cancer AJCC v8; Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8; Metastatic Colorectal Carcinoma; Metastatic Digestive System Carcinoma; Metastatic Gastric Carcinoma; Metastatic Gastroesophageal Junction Adenocarcinoma; Stage III Colorectal Cancer AJCC v8; Stage IV Colorectal Cancer AJCC v8 |
National Cancer Institute (NCI) |
2021-08-13 | PHASE1 |
| NCT02912559 | ACTIVE_NOT_RECRUITING | Colon Adenocarcinoma; DNA Repair Disorder; Lynch Syndrome; Stage III Colon Cancer AJCC v8 |
National Cancer Institute (NCI) |
2017-10-16 | PHASE3 |
| NCT04169828 | COMPLETED | Juvenile Idiopathic Arthritis |
University of British Columbia |
2019-08-02 | |
| NCT06186154 | UNKNOWN | Mitochondrial DNA Deletion; Macrocytosis |
University of British Columbia |
2024-01 | PHASE1 |
| NCT05363007 | UNKNOWN | Metastatic Pancreatic Cancer |
National Taiwan University Hospital |
2022-05-01 | PHASE2 |
| NCT04371224 | UNKNOWN | Pancreatic Cancer |
Seoul National University Hospital |
2020-06-23 | PHASE2 |
| NCT04447092 | UNKNOWN | Pancreatic Cancer; Chemotherapy Effect |
Seoul National University Hospital |
2020-07-01 | PHASE2 |
| NCT04752696 | COMPLETED | Pancreatic Ductal Adenocarcinoma |
Cardiff Oncology |
2021-05-25 | PHASE2 |
| NCT04539808 | ACTIVE_NOT_RECRUITING | Pancreatic Adenocarcinoma; Stage 0 Pancreatic Cancer American Joint Committee on Cancer v8; Stage I Pancreatic Cancer American Joint Committee on Cancer v8; Stage III Pancreatic Cancer American Joint Committee on Cancer v8; Stage IV Pancreatic Cancer American Joint Committee on Cancer v8 |
OHSU Knight Cancer Institute |
2021-05-27 | PHASE2 |
| NCT05628038 | RECRUITING | Recurrent Rectal Cancer |
Fudan University |
2022-11-30 | PHASE2 |
| NCT01628211 | UNKNOWN | Colorectal Cancer |
National Cancer Institute, Naples |
2012-04 | PHASE2 |
| NCT04562558 | ACTIVE_NOT_RECRUITING | Gestational Trophoblastic Tumor; Gestational Trophoblastic Neoplasia; Stage I Gestational Trophoblastic Tumor; Stage II Gestational Trophoblastic Tumor; Stage III Gestational Trophoblastic Tumor; Invasive Mole; Choriocarcinoma |
xiang yang |
2020-09-29 | |
| NCT05313282 | UNKNOWN | C-staged Hepatocellular Carcinoma in BCLC Classification |
Sun Yat-sen University |
2022-06-15 | PHASE3 |
| NCT05319639 | RECRUITING | Gastric Cancer Stage IV |
Fujian Cancer Hospital |
2023-02-16 | PHASE1; PHASE2 |
| NCT02419495 | TERMINATED | Advanced Malignant Solid Neoplasm; Clinical Stage III Cutaneous Melanoma AJCC v8; Clinical Stage IV Cutaneous Melanoma AJCC v8; Fallopian Tube Carcinoma; Metastatic Lung Non-Small Cell Carcinoma; Metastatic Malignant Solid Neoplasm; Metastatic Melanoma; Metastatic Renal Cell Carcinoma; Ovarian Carcinoma; Pathologic Stage III Cutaneous Melanoma AJCC v8; Pathologic Stage IIIA Cutaneous Melanoma AJCC v8; Pathologic Stage IIIB Cutaneous Melanoma AJCC v8; Pathologic Stage IIIC Cutaneous Melanoma AJCC v8; Pathologic Stage IIID Cutaneous Melanoma AJCC v8; Pathologic Stage IV Cutaneous Melanoma AJCC v8; Primary Peritoneal Carcinoma; Stage III Lung Cancer AJCC v8; Stage III Renal Cell Cancer AJCC v8; Stage IIIA Lung Cancer AJCC v8; Stage IIIB Lung Cancer AJCC v8; Stage IIIC Lung Cancer AJCC v8; Stage IV Lung Cancer AJCC v8; Stage IV Renal Cell Cancer AJCC v8; Stage IVA Lung Cancer AJCC v8; Stage IVB Lung Cancer AJCC v8; Triple-Negative Breast Carcinoma; Unresectable Lung Non-Small Cell Carcinoma; Unresectable Melanoma; Unresectable Renal Cell Carcinoma |
M.D. Anderson Cancer Center |
2015-06-26 | PHASE1 |
| NCT05048524 | UNKNOWN | Pancreatic Ductal Adenocarcinoma; Pancreas Cancer |
National Health Research Institutes, Taiwan |
2021-09-03 | PHASE2 |
| NCT02138617 | COMPLETED | Colon Cancer |
UNC Lineberger Comprehensive Cancer Center |
2014-05-06 | PHASE2 |
| NCT06403189 | Not yet recruiting | Plexus Choroideus|Metabolic Syndrome |
Assistance Publique - Hôpitaux de Paris |
2024-07-01 | Not Applicable |
| NCT00878254 | COMPLETED | Mantle-Cell Lymphoma |
University of Miami |
2009-03-25 | PHASE2 |
| NCT05251727 | TERMINATED | Chemotherapy-induced Peripheral Neuropathy |
Veloxis Pharmaceuticals |
2022-03-24 | PHASE1 |
| NCT05383352 | COMPLETED | Metastatic Pancreatic Adenocarcinoma |
Ipsen |
2022-05-30 | PHASE1 |
| NCT03970252 | COMPLETED | Borderline Resectable Pancreatic Adenocarcinoma; Resectable Pancreatic Ductal Adenocarcinoma |
Jonsson Comprehensive Cancer Center |
2019-07-24 | EARLY_PHASE1 |
| NCT06197438 | UNKNOWN | Gastric Cancer |
Fujian Cancer Hospital |
2024-01-01 | PHASE2 |
| NCT02720068 | COMPLETED | Neoplasms |
Merck Sharp & Dohme LLC |
2016-05-02 | PHASE1 |
| NCT04736485 | COMPLETED | Gastric Cancer by AJCC V8 Stage; Resectable Carcinoma |
Centre Francois Baclesse |
2021-06-28 | PHASE2 |
| NCT05839470 | UNKNOWN | Colorectal Cancer |
Fujian Cancer Hospital |
2023-11-19 | PHASE2 |
| NCT04882241 | COMPLETED | Gastric Cancer; Gastroesophageal Junction Cancer |
Merck Sharp & Dohme LLC |
2020-07-29 | PHASE3 |
| NCT06010277 | UNKNOWN | NSCLC; Mesothelioma; Thymoma |
Amphia Hospital |
2023-02-06 | PHASE4 |
| NCT05004350 | COMPLETED | BRAF V600E; Metastatic Colorectal Cancer |
Pierre Fabre Medicament |
2021-09-14 | PHASE2 |
| NCT05615012 | COMPLETED | Healthy Participants |
Bristol-Myers Squibb |
2022-11-11 | PHASE1 |
| NCT03817320 | ACTIVE_NOT_RECRUITING | ALL, Childhood; Lymphoblastic Lymphoma, Childhood; Lymphoblastic Leukemia, Acute, Childhood |
Therapeutic Advances in Childhood Leukemia Consortium |
2019-02-12 | PHASE1; PHASE2 |
| NCT04034459 | UNKNOWN | Metastatic Colorectal Cancer |
Ludwig-Maximilians - University of Munich |
2016-11-25 | PHASE2 |
| NCT04825288 | COMPLETED | Pancreatic Cancer |
XBiotech, Inc. |
2021-05-27 | PHASE1; PHASE2 |
| NCT00488605 | WITHDRAWN | Leukemia |
University of New Mexico |
2023-08-01 | PHASE3 |
| NCT04068103 | ACTIVE_NOT_RECRUITING | Colon Adenocarcinoma; Stage IIA Colon Cancer AJCC v8 |
NRG Oncology |
2019-12-16 | PHASE2; PHASE3 |
| NCT04513951 | COMPLETED | Metastatic Colorectal Cancer |
Gruppo Oncologico del Nord-Ovest |
2020-04-01 | PHASE2 |
| NCT02003222 | ACTIVE_NOT_RECRUITING | Acute Lymphoblastic Leukemia; B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative |
National Cancer Institute (NCI) |
2014-05-19 | PHASE3 |
| NCT04164069 | COMPLETED | Advanced Colorectal Carcinoma; Metastatic Colorectal Carcinoma; Stage IV Colorectal Cancer AJCC v8; Stage IVA Colorectal Cancer AJCC v8; Stage IVB Colorectal Cancer AJCC v8; Stage IVC Colorectal Cancer AJCC v8; Stage II Colon Cancer; Stage II Rectal Cancer; Stage III Colon Cancer; Stage III Rectal Cancer; Esophageal Cancer; Pancreatic Cancer; Bile Duct Cancer; Gastric Cancer; Gall Bladder Cancer; Small Bowel Adenocarcinoma |
Anne Noonan |
2020-09-02 | PHASE1 |
| NCT04761614 | COMPLETED | Metastatic Colorectal Carcinoma; Stage IV Colorectal Cancer AJCC v8; Stage IVA Colorectal Cancer AJCC v8; Stage IVB Colorectal Cancer AJCC v8; Stage IVC Colorectal Cancer AJCC v8 |
Ning Jin |
2021-04-02 | PHASE1 |
| NCT03279289 | COMPLETED | Metastatic Colorectal Cancer |
Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD) |
2017-10-25 | PHASE2 |
| NCT04937738 | TERMINATED | Gastric Cancer |
Ukrainian Society of Clinical Oncology |
2021-07-21 | PHASE2 |
| NCT05251038 | WITHDRAWN | Pancreatic Cancer; Unresectable Pancreatic Cancer; Metastatic Pancreatic Cancer; KRAS P.G12C |
Devalingam Mahalingam |
2022-09-13 | PHASE1; PHASE2 |
| NCT05009953 | TERMINATED | Advanced Biliary Tract Cancer; Intrahepatic Cholangiocarcinoma; Extrahepatic Cholangiocarcinoma; Gallbladder Carcinoma |
CSPC Ouyi Pharmaceutical Co., Ltd. |
2021-09-01 | PHASE2 |
| NCT03712397 | COMPLETED | Head & Neck Cancer |
National Health Research Institutes, Taiwan |
2018-12-24 | PHASE2 |
| NCT02883049 | COMPLETED | B Acute Lymphoblastic Leukemia; B Acute Lymphoblastic Leukemia, BCR-ABL1-Like; Central Nervous System Leukemia; Testicular Leukemia |
National Cancer Institute (NCI) |
2012-02-29 | PHASE3 |
| NCT04155671 | UNKNOWN | Gastric Cancer |
Fujian Cancer Hospital |
2019-12-01 | PHASE2 |
| NCT03314935 | COMPLETED | Biliary Tract Cancer (BTC); Colorectal Cancer (CRC); Endometrial Cancer; Gastroesophageal Cancer (GC); Ovarian Cancer; Solid Tumors |
Incyte Corporation |
2017-11-21 | PHASE1; PHASE2 |
| NCT03750786 | COMPLETED | Colo-rectal Cancer |
Isofol Medical AB |
2018-12-18 | PHASE3 |
| NCT03504397 | ACTIVE_NOT_RECRUITING | Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or Cancer; Locally Advanced Unresectable Gastric Adenocarcinoma or Cancer; Metastatic Gastric Adenocarcinoma or Cancer; Metastatic Gastroesophageal Junction (GEJ) Adenocarcinoma |
Astellas Pharma Global Development, Inc. |
2018-06-21 | PHASE3 |
| NCT04097444 | UNKNOWN | Metastatic Colorectal Cancer |
Chugai Pharmaceutical |
2019-10-11 | PHASE2 |
| NCT04354662 | COMPLETED | Gastric Cancer |
Tianjin Medical University Cancer Institute and Hospital |
2020-05-25 | PHASE2 |
| NCT02553460 | ACTIVE_NOT_RECRUITING | Acute Lymphoblastic Leukemia |
St. Jude Children's Research Hospital |
2016-01-29 | PHASE1; PHASE2 |
| NCT03206151 | COMPLETED | Metastatic Colorectal Cancer |
Taizhou Mabtech Pharmaceutical Co.,Ltd |
2017-12-12 | PHASE3 |
| NCT04886193 | UNKNOWN | Chemotherapy; Gastric Cancer |
Guangdong Provincial Hospital of Traditional Chinese Medicine |
2021-04-16 | |
| NCT03300544 | TERMINATED | Locally Advanced Rectal Adenocarcinoma; Metastatic Rectal Adenocarcinoma; Rectal Adenocarcinoma; Stage III Rectal Cancer AJCC v7; Stage IIIA Rectal Cancer AJCC v7; Stage IIIB Rectal Cancer AJCC v7; Stage IIIC Rectal Cancer AJCC v7; Stage IV Rectal Cancer AJCC v7; Stage IVA Rectal Cancer AJCC v7; Stage IVB Rectal Cancer AJCC v7 |
National Cancer Institute (NCI) |
2019-05-14 | PHASE1 |
| NCT02833753 | COMPLETED | Colorectal Cancer; Appendix Cancer; Peritoneal Carcinomatosis |
University of Massachusetts, Worcester |
2016-07 | PHASE1 |
| NCT02539537 | COMPLETED | Pancreatic Cancer; Carcinoma |
UNICANCER |
2015-10-23 | PHASE3 |
| NCT03788226 | UNKNOWN | Gastric Cancer Stage III |
Fujian Cancer Hospital |
2019-02-01 | PHASE3 |
| NCT03698461 | COMPLETED | Colorectal Neoplasms; Neoplasm Metastasis; Colonic Neoplasms; Rectal Neoplasms |
Asan Medical Center |
2019-05-15 | PHASE2 |
| NCT04121039 | UNKNOWN | Gastric Adenocarcinoma; Advanced Cancer |
Fujian Cancer Hospital |
2019-12 | PHASE2 |
| NCT03528785 | UNKNOWN | Pancreatic Adenocarcinoma |
Centro Ricerche Cliniche di Verona |
2018-03-02 | PHASE2 |
| NCT01897454 | TERMINATED | Pancreatic Adenocarcinoma; Stage IIA Pancreatic Cancer; Stage IIB Pancreatic Cancer; Stage III Pancreatic Cancer |
Albert Einstein College of Medicine |
2012-01-27 | PHASE2 |
| NCT04595929 | RECRUITING | Peritoneal Carcinomatosis; Gastric Cancer |
St. Petersburg State Pavlov Medical University |
2020-02-10 | |
| NCT01926197 | COMPLETED | Pancreatic Cancer |
Stanford University |
2013-08-14 | PHASE3 |
| NCT03703063 | UNKNOWN | Pancreatic Adenocarcinoma |
Benaroya Research Institute |
2018-09-17 | PHASE1 |
| NCT03374254 | COMPLETED | Metastatic Colorectal Cancer |
Merck Sharp & Dohme LLC |
2018-02-16 | PHASE1 |
| NCT04430985 | WITHDRAWN | Metastatic Colorectal Cancer |
Dorte Nielsen |
2020-09-30 | PHASE2 |
| NCT03050814 | TERMINATED | Colorectal Tumors; Colorectal Neoplasms; Colorectal Carcinoma; Colorectal Adenocarcinoma; Colorectal Cancer |
National Cancer Institute (NCI) |
2017-04-05 | PHASE2 |
| NCT02730546 | COMPLETED | Gastric Cardia Adenocarcinoma; Gastroesophageal Junction Adenocarcinoma; Stage IB Gastric Cancer AJCC v7; Stage II Gastric Cancer AJCC v7; Stage IIA Gastric Cancer AJCC v7; Stage IIB Gastric Cancer AJCC v7; Stage IIIA Gastric Cancer AJCC v7; Stage IIIB Gastric Cancer AJCC v7 |
Mayo Clinic |
2016-06-24 | PHASE1; PHASE2 |
| NCT03791905 | UNKNOWN | Neoplasm, Esophageal; Squamous Cell Carcinoma |
Mian XI |
2019-01-15 | PHASE2 |
| NCT02101853 | ACTIVE_NOT_RECRUITING | Recurrent B Acute Lymphoblastic Leukemia |
National Cancer Institute (NCI) |
2014-12-17 | PHASE3 |
| NCT04034173 | TERMINATED | Treatment Related Cancer |
Ludwig-Maximilians - University of Munich |
2019-07-24 | PHASE2 |
| NCT02620865 | COMPLETED | Metastatic Pancreatic Adenocarcinoma; Recurrent Pancreatic Carcinoma; Stage III Pancreatic Cancer; Stage IV Pancreatic Cancer |
Barbara Ann Karmanos Cancer Institute |
2015-12 | PHASE1; PHASE2 |
| NCT03518112 | TERMINATED | Philadelphia Chromosome Negative; Recurrent B Acute Lymphoblastic Leukemia; Refractory B Acute Lymphoblastic Leukemia |
M.D. Anderson Cancer Center |
2018-04-18 | PHASE2 |
| NCT04299880 | COMPLETED | Oncology |
Sumitomo Pharma America, Inc. |
2020-02-24 | PHASE1 |
| NCT04170179 | UNKNOWN | Hepatocellular Carcinoma |
Sun Yat-sen University |
2019-11-19 | PHASE2 |
| NCT03337087 | UNKNOWN | Metastatic Biliary Tract Carcinoma; Metastatic Colorectal Carcinoma; Metastatic Gastroesophageal Junction Adenocarcinoma; Metastatic Malignant Digestive System Neoplasm; Metastatic Pancreatic Adenocarcinoma; Stage IV Colorectal Cancer AJCC v7; Stage IV Pancreatic Cancer AJCC v6 and v7; Stage IVA Colorectal Cancer AJCC v7; Stage IVB Colorectal Cancer AJCC v7 |
Academic and Community Cancer Research United |
2018-11-02 | PHASE1; PHASE2 |
| NCT03722498 | WITHDRAWN | Hepatocellular Carcinoma |
Sun Yat-sen University |
2018-06-01 | PHASE2 |
| NCT03142516 | COMPLETED | Colorectal Neoplasms; Colorectal Carcinoma; Colorectal Cancer Metastatic; Neoplasm Metastasis |
Grupo Espanol Multidisciplinario del Cancer Digestivo |
2017-10-31 | PHASE2 |
| NCT03043729 | COMPLETED | Rectal Cancer; Rectosigmoid Cancer |
AIO-Studien-gGmbH |
2017-03-06 | PHASE2 |
| NCT02870036 | UNKNOWN | Advanced Solid Tumor; Advanced/Metastatic Colorectal Cancer |
Haihe Biopharma Co., Ltd. |
2016-10 | PHASE1 |
| NCT03000374 | COMPLETED | Rectal Cancer |
Grupo Espanol Multidisciplinario del Cancer Digestivo |
2017-05-30 | PHASE2 |
| NCT03711240 | UNKNOWN | Colorectal Cancer |
National Cheng-Kung University Hospital |
2019-01-08 | PHASE2 |
| NCT05013164 | Completed | Autism Spectrum Disorder |
Nishtar Medical University |
2020-10-01 | Phase 2 |
| NCT04060030 | Recruiting | Autism Spectrum Disorder|Language Disorders |
Southwest Autism Research & Resource Center|Autism Speaks|State University of New York - Downstate Medical Center |
2020-10-08 | Phase 2 |
| NCT03524508 | COMPLETED | Metastatic Biliary Tract Cancer |
Changhoon Yoo |
2018-09-04 | PHASE2 |
| NCT02828358 | COMPLETED | Acute Leukemia of Ambiguous Lineage; B Acute Lymphoblastic Leukemia; Mixed Phenotype Acute Leukemia |
National Cancer Institute (NCI) |
2017-04-01 | PHASE2 |
| NCT04060017 | Recruiting | Autism Spectrum Disorder|Language Disorders |
Southwest Autism Research & Resource Center|State University of New York - Downstate Medical Center|United States Department of Defense |
2020-09-22 | Phase 2 |
| NCT02529774 | UNKNOWN | Resected Liver Metastases From Colorectal Cancer |
Ye Xu |
2015-09 | PHASE2; PHASE3 |
| NCT03099486 | TERMINATED | Colorectal Cancer |
Fox Chase Cancer Center |
2017-10-06 | PHASE2 |
| NCT02959541 | UNKNOWN | Colon Cancer; Chemotherapy |
Vastra Gotaland Region |
2016-09 | |
| NCT02921256 | COMPLETED | Rectal Adenocarcinoma; Stage II Rectal Cancer AJCC v7; Stage III Rectal Cancer AJCC v7 |
National Cancer Institute (NCI) |
2017-01-11 | PHASE2 |
| NCT03559348 | COMPLETED | Pancreatic Adenocarcinoma |
National Health Research Institutes, Taiwan |
2018-04-03 | PHASE2 |
| NCT03488225 | TERMINATED | Acute Lymphoblastic Leukemia in Remission; B Acute Lymphoblastic Leukemia; B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative |
M.D. Anderson Cancer Center |
2018-03-28 | PHASE2 |
| NCT02112916 | ACTIVE_NOT_RECRUITING | Adult T Acute Lymphoblastic Leukemia; Ann Arbor Stage II Adult Lymphoblastic Lymphoma; Ann Arbor Stage II Childhood Lymphoblastic Lymphoma; Ann Arbor Stage III Adult Lymphoblastic Lymphoma; Ann Arbor Stage III Childhood Lymphoblastic Lymphoma; Ann Arbor Stage IV Adult Lymphoblastic Lymphoma; Ann Arbor Stage IV Childhood Lymphoblastic Lymphoma; Childhood T Acute Lymphoblastic Leukemia |
National Cancer Institute (NCI) |
2014-10-04 | PHASE3 |
| NCT01788189 | COMPLETED | B-cell Lymphoma |
University Hospital, Essen |
2013-01 | PHASE1; PHASE2 |
| NCT03464968 | COMPLETED | Biliary Cancer Metastatic |
Seoul National University Bundang Hospital |
2015-07-29 | PHASE2 |
| NCT02641691 | COMPLETED | Cancer of Rectum; Cancer of the Rectum; Neoplasm, Rectum; Rectal Cancer; Rectum Cancer; Rectum Neoplasms; Adenocarcinoma of the Rectum |
Washington University School of Medicine |
2016-05-27 | PHASE2 |
| NCT02099175 | UNKNOWN | Sinonasal Tumors |
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano |
2013-11 | PHASE2 |
| NCT03563144 | WITHDRAWN | Metastatic Pancreatic Cancer |
ImmunityBio, Inc. |
2018-08 | PHASE2 |
| NCT01700569 | TERMINATED | Grade IV Astrocytoma; Glioblastoma |
Institut Cancerologie de l'Ouest |
2013-01 | PHASE1 |
| NCT03812783 | UNKNOWN | Hepatocellular Carcinoma |
Sun Yat-sen University |
2018-11-05 | PHASE2 |
| NCT03606928 | COMPLETED | Gastric Cancer |
Ruijin Hospital |
2018-07-01 | PHASE1; PHASE2 |
| NCT03300609 | TERMINATED | Colorectal Adenocarcinoma; RAS Wild Type; Stage III Colorectal Cancer AJCC v7; Stage IIIA Colorectal Cancer AJCC v7; Stage IIIB Colorectal Cancer AJCC v7; Stage IIIC Colorectal Cancer AJCC v7; Stage IV Colorectal Cancer AJCC v7; Stage IVA Colorectal Cancer AJCC v7; Stage IVB Colorectal Cancer AJCC v7 |
University of Southern California |
2018-02-27 | PHASE3 |
| NCT02935764 | UNKNOWN | Colorectal Carcinoma |
Fudan University |
2016-10 | PHASE3 |
| NCT03707639 | UNKNOWN | Gastric Adenocarcinoma |
Fujian Cancer Hospital |
2018-11 | PHASE2 |
| NCT00267865 | COMPLETED | AIDS-Related-Primary Central Nervous System Lymphoma |
National Cancer Institute (NCI) |
2006-09-14 | PHASE2 |
| NCT02625610 | COMPLETED | Unresectable, Locally Advanced or Metastatic, Adenocarcinoma of the Stomach, or of the Gastro Esophageal Junction |
EMD Serono Research & Development Institute, Inc. |
2015-12-24 | PHASE3 |
| NCT03812770 | UNKNOWN | Hepatocellular Carcinoma |
Sun Yat-sen University |
2018-08-04 | PHASE2 |
| NCT01652196 | COMPLETED | Mucinous Adenocarcinoma of the Colon; Mucinous Adenocarcinoma of the Rectum; Signet Ring Adenocarcinoma of the Colon; Signet Ring Adenocarcinoma of the Rectum; Stage IV Colon Cancer; Stage IV Rectal Cancer |
John Hays |
2012-11-14 | PHASE2 |
| NCT01862003 | COMPLETED | Metastatic Colorectal Cancer; Recurrent Colorectal Cancer |
University College, London |
2014-05 | PHASE2 |
| NCT01913639 | COMPLETED | Esophageal Cancer; Gastric Cancer |
Memorial Sloan Kettering Cancer Center |
2013-07 | PHASE2 |
| NCT03069950 | WITHDRAWN | Colorectal Adenocarcinoma Metastatic to the Liver |
Memorial Sloan Kettering Cancer Center |
2017-02-28 | PHASE2 |
| NCT02545504 | COMPLETED | Gastric Adenocarcinoma |
Gilead Sciences |
2015-10-13 | PHASE3 |
| NCT02890355 | COMPLETED | Metastatic Pancreatic Adenocarcinoma; Recurrent Pancreatic Carcinoma; Stage IV Pancreatic Cancer AJCC v6 and v7 |
National Cancer Institute (NCI) |
2016-10-27 | PHASE2 |
| NCT01190930 | COMPLETED | Acute Lymphoblastic Leukemia; Adult B Lymphoblastic Lymphoma; Ann Arbor Stage I B Lymphoblastic Lymphoma; Ann Arbor Stage II B Lymphoblastic Lymphoma; Childhood B Acute Lymphoblastic Leukemia; Childhood B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1; Childhood B Lymphoblastic Lymphoma; Down Syndrome; Hypodiploid B Acute Lymphoblastic Leukemia; Philadelphia Chromosome Positive |
Children's Oncology Group |
2010-08-11 | PHASE3 |
| NCT02928224 | COMPLETED | BRAF V600E-mutant Metastatic Colorectal Cancer |
Pfizer |
2016-10-13 | PHASE3 |
| NCT03294252 | TERMINATED | Digestive Cancer |
Institut Cancerologie de l'Ouest |
2017-05-24 | PHASE1; PHASE2 |
| NCT03197584 | WITHDRAWN | Ovarian Cancer |
ImmunityBio, Inc. |
2017-12 | PHASE1; PHASE2 |
| NCT03085914 | COMPLETED | Solid Tumor |
Incyte Corporation |
2017-05-02 | PHASE1; PHASE2 |
| NCT03169777 | WITHDRAWN | Colorectal Cancer |
ImmunityBio, Inc. |
2018-08 | PHASE1; PHASE2 |
| NCT03167177 | WITHDRAWN | Melanoma |
ImmunityBio, Inc. |
2017-12 | PHASE1; PHASE2 |
| NCT03169764 | WITHDRAWN | Head and Neck Squamous Cell Carcinoma |
ImmunityBio, Inc. |
2017-12 | PHASE1; PHASE2 |
| NCT03244774 | UNKNOWN | Gastric Adenocarcinoma |
Fujian Cancer Hospital |
2018-01-01 | PHASE1 |
| NCT05121571 | COMPLETED | Hepatocellular Carcinoma |
Sun Yat-sen University |
2016-04-21 | |
| NCT02688023 | UNKNOWN | Colorectal Cancer |
Chinese Academy of Medical Sciences |
2014-03 | PHASE2 |
| NCT02319304 | TERMINATED | Rectal Adenocarcinoma |
University of Maryland, Baltimore |
2015-03 | PHASE2 |
| NCT02319018 | COMPLETED | Malignant Digestive System Neoplasm |
National Cancer Institute (NCI) |
2015-08-27 | PHASE1 |
| NCT03387098 | TERMINATED | Pancreatic Cancer |
ImmunityBio, Inc. |
2017-12-28 | PHASE1; PHASE2 |
| NCT02296671 | WITHDRAWN | Esophagogastric Cancer |
Washington University School of Medicine |
2015-02 | PHASE2 |
| NCT01814501 | COMPLETED | Mucinous Adenocarcinoma of the Colon; Mucinous Adenocarcinoma of the Rectum; Recurrent Colon Cancer; Recurrent Rectal Cancer; Signet Ring Adenocarcinoma of the Colon; Signet Ring Adenocarcinoma of the Rectum; Stage IV Colon Cancer; Stage IV Rectal Cancer |
John Hays |
2013-02-01 | PHASE2 |
| NCT02855788 | UNKNOWN | Metastatic Gastric Cancer; Locally Advanced Gastric Cancer |
Huashan Hospital |
2015-05 | PHASE2 |
| NCT01535053 | COMPLETED | Choriocarcinoma; FIGO Stage I Gestational Trophoblastic Tumor; FIGO Stage II Gestational Trophoblastic Tumor; FIGO Stage III Gestational Trophoblastic Tumor; Hydatidiform Mole |
GOG Foundation |
2012-06-18 | PHASE3 |
| NCT02270606 | COMPLETED | Mucinous Adenocarcinoma of the Rectum; Recurrent Rectal Cancer; Signet Ring Adenocarcinoma of the Rectum; Rectal Adenocarcinoma; Stage IIA Rectal Cancer; Stage IIB Rectal Cancer; Stage IIC Rectal Cancer; Stage IIIA Rectal Cancer; Stage IIIB Rectal Cancer; Stage IIIC Rectal Cancer |
Virginia Commonwealth University |
2014-12-04 | PHASE1 |
| NCT02845908 | COMPLETED | Malignant Neoplasm of Stomach Stage IV |
Fujian Cancer Hospital |
2015-11 | PHASE2 |
| NCT02785068 | WITHDRAWN | Colorectal Cancer |
Merrimack Pharmaceuticals |
2016-07 | PHASE1; PHASE2 |
| NCT02779283 | COMPLETED | Acute Lymphoblastic Leukemia; Acute Myeloid Leukemia |
OHSU Knight Cancer Institute |
2016-01-13 | PHASE1 |
| NCT02676323 | TERMINATED | Acute Myeloid Leukemia; Myelodysplastic Syndrome |
St. Jude Children's Research Hospital |
2016-05-03 | PHASE1 |
| NCT01959672 | COMPLETED | Pancreatic Adenocarcinoma; Resectable Pancreatic Carcinoma; Stage I Pancreatic Cancer; Stage IA Pancreatic Cancer; Stage IB Pancreatic Cancer; Stage II Pancreatic Cancer; Stage IIA Pancreatic Cancer; Stage IIB Pancreatic Cancer; Stage III Pancreatic Cancer |
University of Nebraska |
2013-09-06 | PHASE2 |
| NCT02782182 | TERMINATED | Pancreatic Ductal Adenocarcinoma (PDAC) |
University of Chicago |
2016-06-28 | PHASE1 |
| NCT02896907 | COMPLETED | Pancreatic Adenocarcinoma; Recurrent Pancreatic Carcinoma; Stage III Pancreatic Cancer; Stage IV Pancreatic Cancer; Unresectable Pancreatic Carcinoma |
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University |
2016-10-18 | EARLY_PHASE1 |
| NCT01871571 | TERMINATED | Mucinous Adenocarcinoma of the Rectum; Signet Ring Adenocarcinoma of the Rectum; Stage IIA Rectal Cancer; Stage IIB Rectal Cancer; Stage IIC Rectal Cancer; Stage IIIA Rectal Cancer; Stage IIIB Rectal Cancer; Stage IIIC Rectal Cancer |
University of Southern California |
2013-08-02 | PHASE2 |
| NCT01526135 | COMPLETED | Pancreatic Adenocarcinoma (Ductal Adenocarcinoma) |
UNICANCER |
2012-04-16 | PHASE3 |
| NCT01737671 | COMPLETED | Brain Tumor; Malignant Neoplasm of Fourth Ventricle of Brain |
M.D. Anderson Cancer Center |
2012-12-27 | EARLY_PHASE1 |
| NCT01503372 | COMPLETED | Advanced Gastric Cancer |
Charite University, Berlin, Germany |
2011-11 | PHASE2 |
| NCT02293109 | COMPLETED | Contiguous Stage II Adult Lymphoblastic Lymphoma; Noncontiguous Stage II Adult Lymphoblastic Lymphoma; Stage I Adult Lymphoblastic Lymphoma; Stage III Adult Lymphoblastic Lymphoma; Stage IV Adult Lymphoblastic Lymphoma; Untreated Adult Acute Lymphoblastic Leukemia |
Mehrdad Abedi, MD |
2015-12-17 | PHASE1 |
| NCT02256800 | COMPLETED | Metastatic Colorectal Cancer |
Jaw-Yuan Wang, MD, PhD |
2014-08-13 | |
| NCT01256398 | COMPLETED | Acute Lymphoblastic Leukemia; Adult B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1 |
National Cancer Institute (NCI) |
2010-12-14 | PHASE2 |
| NCT02413853 | WITHDRAWN | Colorectal Adenocarcinoma; Stage IVA Colorectal Cancer; Stage IVB Colorectal Cancer |
University of Southern California |
2015-11 | PHASE2 |
| NCT01308086 | UNKNOWN | CRC |
Hellenic Oncology Research Group |
2010-10 | PHASE3 |
| NCT02015819 | COMPLETED | Adult Anaplastic Astrocytoma; Adult Anaplastic Oligodendroglioma; Adult Giant Cell Glioblastoma; Adult Glioblastoma; Adult Gliosarcoma; Recurrent Adult Brain Tumor; Anaplastic Oligoastrocytoma |
City of Hope Medical Center |
2014-10-07 | PHASE1 |
| NCT00408005 | COMPLETED | T Acute Lymphoblastic Leukemia; T Lymphoblastic Lymphoma |
National Cancer Institute (NCI) |
2007-01-30 | PHASE3 |
| NCT00557193 | COMPLETED | Acute Lymphoblastic Leukemia; Acute Undifferentiated Leukemia; Childhood T Acute Lymphoblastic Leukemia |
Children's Oncology Group |
2008-01-15 | PHASE3 |
| NCT02508077 | TERMINATED | Recurrent Colorectal Carcinoma; Stage IVA Colorectal Cancer; Stage IVB Colorectal Cancer |
City of Hope Medical Center |
2016-02-16 | PHASE2 |
| NCT02534337 | WITHDRAWN | Hepatocellular Carcinoma |
Guangxi Medical University |
2015-09 | PHASE2; PHASE3 |
| NCT02648425 | COMPLETED | Solid Tumor |
ASLAN Pharmaceuticals |
2014-08-05 | PHASE1 |
| NCT01653470 | COMPLETED | Cancer |
Bristol-Myers Squibb |
2012-10-12 | PHASE1 |
| NCT02486497 | COMPLETED | Pancreatic Cancer |
Seoul National University Hospital |
2015-06 | |
| NCT02981498 | COMPLETED | Hepatocellular Carcinoma |
Sun Yat-sen University |
2015-06 | PHASE2 |
| NCT02987699 | UNKNOWN | HepatoCellular Carcinoma |
Sun Yat-sen University |
2016-11 | PHASE2 |
| NCT00501410 | COMPLETED | Colorectal Cancer |
M.D. Anderson Cancer Center |
2007-04-23 | PHASE1 |
| NCT00544414 | COMPLETED | Head and Neck Cancer |
City of Hope Medical Center |
2000-06-07 | PHASE2 |
| NCT01383343 | COMPLETED | Recurrent Colon Carcinoma; Recurrent Rectal Carcinoma; Stage IVA Colon Cancer; Stage IVA Rectal Cancer; Stage IVB Colon Cancer; Stage IVB Rectal Cancer |
National Cancer Institute (NCI) |
2011-08 | PHASE1 |
| NCT02195180 | COMPLETED | Pancreatic Adenocarcinoma Metastatic |
ERYtech Pharma |
2014-07 | PHASE2 |
| NCT02042443 | COMPLETED | Adult Cholangiocarcinoma; Advanced Adult Hepatocellular Carcinoma; BCLC Stage C Adult Hepatocellular Carcinoma; BCLC Stage D Adult Hepatocellular Carcinoma; Hilar Cholangiocarcinoma; Localized Non-Resectable Adult Liver Carcinoma; Recurrent Adult Liver Carcinoma; Recurrent Childhood Liver Cancer; Recurrent Extrahepatic Bile Duct Carcinoma; Recurrent Gallbladder Carcinoma; Stage II Gallbladder Cancer; Stage III Childhood Hepatocellular Carcinoma; Stage IIIA Gallbladder Cancer; Stage IIIB Gallbladder Cancer; Stage IV Childhood Hepatocellular Carcinoma; Stage IV Distal Bile Duct Cancer; Stage IVA Gallbladder Cancer; Stage IVB Gallbladder Cancer; Unresectable Extrahepatic Bile Duct Carcinoma |
National Cancer Institute (NCI) |
2014-02 | PHASE2 |
| NCT00336024 | COMPLETED | Anaplastic Medulloblastoma; Medulloblastoma; Supratentorial Embryonal Tumor, Not Otherwise Specified; Untreated Childhood Supratentorial Primitive Neuroectodermal Tumor |
Children's Oncology Group |
2007-10-22 | PHASE3 |
| NCT02640365 | COMPLETED | Unresectable Advanced Cancer |
GERCOR - Multidisciplinary Oncology Cooperative Group |
2015-11-18 | PHASE1 |
| NCT01747551 | COMPLETED | Esophageal Cancer; Gastric Cancer |
Dana-Farber Cancer Institute |
2013-01 | PHASE2 |
| NCT01533324 | UNKNOWN | Carcinoma; Liver Diseases; Hepatocellular Carcinoma |
Second Military Medical University |
2011-11 | PHASE2 |
| NCT02311439 | UNKNOWN | Cancer of Pancreas |
Assiut University |
2014-10 | PHASE2; PHASE3 |
| NCT02270788 | COMPLETED | Acute Myeloid Leukemia |
St. Jude Children's Research Hospital |
2015-04-02 | PHASE1 |
| NCT03428529 | COMPLETED | Rectal Neoplasm Malignant |
Instituto Nacional de Cancer, Brazil |
2011-01-12 | PHASE2; PHASE3 |
| NCT00653068 | COMPLETED | Childhood Atypical Teratoid/Rhabdoid Tumor |
Children's Oncology Group |
2009-02-10 | PHASE3 |
| NCT01364376 | COMPLETED | Stomach Neoplasms |
Zhejiang University |
2011-06 | |
| NCT01231399 | COMPLETED | Adenocarcinoma of the Esophagus; Adenocarcinoma of the Gastroesophageal Junction; Diffuse Adenocarcinoma of the Stomach; Intestinal Adenocarcinoma of the Stomach; Mixed Adenocarcinoma of the Stomach; Recurrent Esophageal Cancer; Recurrent Gastric Cancer; Stage IV Esophageal Cancer; Stage IV Gastric Cancer |
City of Hope Medical Center |
2012-02 | PHASE1; PHASE2 |
| NCT00792948 | ACTIVE_NOT_RECRUITING | Acute Lymphoblastic Leukemia; Adult B Acute Lymphoblastic Leukemia; Adult B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1; Adult L1 Acute Lymphoblastic Leukemia; Adult L2 Acute Lymphoblastic Leukemia; Adult T Acute Lymphoblastic Leukemia; Recurrent Adult Acute Lymphoblastic Leukemia |
National Cancer Institute (NCI) |
2009-09-01 | PHASE2 |
| NCT01362361 | COMPLETED | Colorectal Cancer |
Martin-Luther-Universität Halle-Wittenberg |
2011-06 | PHASE2 |
| NCT02379091 | COMPLETED | Rheumatoid Arthritis |
Takeda |
2014-12-17 | PHASE2 |
| NCT01786538 | WITHDRAWN | Metastatic Colorectal Cancer |
Asan Medical Center |
2013-06 | PHASE3 |
| NCT01183663 | COMPLETED | Advanced Cancers |
M.D. Anderson Cancer Center |
2010-08 | PHASE1 |
| NCT02500940 | UNKNOWN | Nasopharyngeal Carcinoma |
Taichung Veterans General Hospital |
2015-05 | PHASE3 |
| NCT01765582 | TERMINATED | Colorectal Neoplasms |
Hoffmann-La Roche |
2013-01-23 | PHASE2 |
| NCT00381680 | COMPLETED | B-cell Childhood Acute Lymphoblastic Leukemia; L1 Childhood Acute Lymphoblastic Leukemia; L2 Childhood Acute Lymphoblastic Leukemia; Intermediate Risk Recurrent Childhood Acute Lymphoblastic Leukemia |
Children's Oncology Group |
2007-03 | PHASE3 |
| NCT02046538 | WITHDRAWN | Adenocarcinoma of the Colon; Adenocarcinoma of the Rectum |
Weill Medical College of Cornell University |
2014-02 | PHASE2 |
| NCT01228734 | COMPLETED | Metastatic Colorectal Cancer |
Merck KGaA, Darmstadt, Germany |
2010-09-09 | PHASE3 |
| NCT00525785 | COMPLETED | Stomach Cancer; Gastric Cancer |
M.D. Anderson Cancer Center |
2004-01 | PHASE2 |
| NCT01307956 | TERMINATED | Adenocarcinoma of the Gastroesophageal Junction; Esophageal Adenocarcinoma; Stage IIA Esophageal Cancer; Stage IIB Esophageal Cancer |
University of Nebraska |
2011-02-28 | PHASE2 |
| NCT00952029 | COMPLETED | Colorectal Cancer |
Federation Francophone de Cancerologie Digestive |
2010-03 | PHASE2; PHASE3 |
| NCT01980407 | UNKNOWN | Gastric Cancer |
Jilin Provincial Tumor Hospital |
2013-11 | PHASE2 |
| NCT01263171 | COMPLETED | Colorectal Cancer |
Cardiff University |
2012-04 | PHASE2 |
| NCT01333033 | COMPLETED | Adenocarcinoma of the Gastroesophageal Junction; Esophageal Cancer |
Alliance for Clinical Trials in Oncology |
2011-07 | PHASE2 |
| NCT01442649 | COMPLETED | Colorectal Cancer |
UNICANCER |
2010-12 | PHASE2 |
| NCT02426450 | UNKNOWN | Hepatocellular Carcinoma |
Sun Yat-sen University |
2015-04 | PHASE2 |
| NCT01900431 | COMPLETED | Uveitis |
Sanofi |
2013-10 | PHASE2 |
| NCT00450801 | COMPLETED | Lymphoma |
University of Miami |
2004-04 | PHASE2 |
| NCT01670721 | COMPLETED | Colorectal Cancer Metastatic |
Sanofi |
2012-08 | PHASE3 |
| NCT01715233 | COMPLETED | Metastatic Esophageal Cancer; Gastroesophageal Cancer; Gastric Cancer |
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins |
2012-12 | PHASE2 |
| NCT00720109 | COMPLETED | Acute Lymphoblastic Leukemia; Adult B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1; Childhood B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1 |
National Cancer Institute (NCI) |
2008-07-14 | PHASE2; PHASE3 |
| NCT01050426 | TERMINATED | Pancreatic Cancer |
Royal Marsden NHS Foundation Trust |
2009-03 | PHASE2 |
| NCT01652482 | COMPLETED | Colorectal Cancer |
Genentech, Inc. |
2012-10 | PHASE2 |
| NCT01748851 | TERMINATED | Gastric Carcinoma Stage IV |
Dong-A University Hospital |
2012-12 | PHASE3 |
| NCT01269216 | COMPLETED | Rectal Cancer |
Yonsei University |
2008-10 | PHASE2 |
| NCT01472029 | COMPLETED | Adenocarcinoma of the Gastroesophageal Junction; Adenocarcinoma of the Stomach |
AIO-Studien-gGmbH |
2011-12 | PHASE2 |
| NCT00957905 | COMPLETED | Recurrent Extragonadal Seminoma; Recurrent Malignant Extragonadal Germ Cell Tumor; Recurrent Malignant Extragonadal Non-Seminomatous Germ Cell Tumor; Recurrent Malignant Testicular Germ Cell Tumor; Recurrent Ovarian Germ Cell Tumor; Stage III Testicular Cancer; Stage IV Extragonadal Non-Seminomatous Germ Cell Tumor; Stage IV Extragonadal Seminoma; Stage IV Ovarian Germ Cell Tumor |
National Cancer Institute (NCI) |
2009-06 | PHASE2 |
| NCT00400946 | COMPLETED | Drug/Agent Toxicity by Tissue/Organ; Leukemia |
Dana-Farber Cancer Institute |
2005-04 | PHASE3 |
| NCT01183780 | COMPLETED | Colorectal Cancer |
Eli Lilly and Company |
2010-12-02 | PHASE3 |
| NCT01941173 | WITHDRAWN | Recurrent Colon Cancer; Recurrent Rectal Cancer; Stage IVA Colon Cancer; Stage IVA Rectal Cancer; Stage IVB Colon Cancer; Stage IVB Rectal Cancer |
City of Hope Medical Center |
2014-01 | |
| NCT01467115 | COMPLETED | Head and Neck Cancer |
Drexel University College of Medicine |
2010-03 | PHASE2 |
| NCT00002842 | COMPLETED | Colorectal Cancer; Metastatic Cancer |
City of Hope Medical Center |
1994-09 | PHASE2 |
| NCT00941499 | COMPLETED | Advanced Cancers |
M.D. Anderson Cancer Center |
2009-07 | PHASE1 |
| NCT01720563 | TERMINATED | Cancer-related Fatigue |
PhytoHealth Corporation |
2012-12 | PHASE2 |
| NCT01229111 | TERMINATED | Adult Primary Cholangiocellular Carcinoma; Advanced Adult Primary Liver Cancer; Cholangiocarcinoma of the Extrahepatic Bile Duct; Cholangiocarcinoma of the Gallbladder; Localized Unresectable Adult Primary Liver Cancer; Periampullary Adenocarcinoma; Recurrent Adult Primary Liver Cancer; Recurrent Extrahepatic Bile Duct Cancer; Recurrent Gallbladder Cancer; Unresectable Extrahepatic Bile Duct Cancer; Unresectable Gallbladder Cancer |
National Cancer Institute (NCI) |
2010-10 | PHASE2 |
| NCT01399684 | COMPLETED | Metastatic Colorectal Cancer |
Genentech, Inc. |
2011-11 | PHASE2 |
| NCT00317408 | UNKNOWN | Lymphoma |
European Inter-group Cooperation on Childhood and Adolescent Non Hodgkin Lymphoma |
2004-04 | |
| NCT00103285 | COMPLETED | Acute Lymphoblastic Leukemia; Childhood B Acute Lymphoblastic Leukemia |
Children's Oncology Group |
2005-04-11 | PHASE3 |
| NCT01053390 | COMPLETED | Gallbladder Neoplasms |
Shanghai Jiao Tong University School of Medicine |
2009-10 | PHASE3 |
| NCT01238939 | COMPLETED | Advanced Solid Tumors; Metastatic Colorectal Cancer |
Nippon Kayaku Co., Ltd. |
2010-08 | PHASE1 |
| NCT00098787 | COMPLETED | Colorectal Cancer |
Eastern Cooperative Oncology Group |
2005-09-08 | PHASE2 |
| NCT01074996 | UNKNOWN | Pancreatic Cancer |
The Affiliated Hospital of the Chinese Academy of Military Medical Sciences |
2010-02 | PHASE2 |
| NCT01014767 | TERMINATED | Brain Cancer; Choroid Plexus Tumors |
Tufts Medical Center |
2009-11 | PHASE3 |
| NCT01246960 | COMPLETED | Stomach Cancer; Esophageal Cancer |
Eli Lilly and Company |
2011-04 | PHASE2 |
| NCT01063192 | UNKNOWN | Locally Advanced Pancreatic Cancer |
National Health Research Institutes, Taiwan |
2009-11 | PHASE2 |
| NCT00321685 | COMPLETED | Rectal Adenocarcinoma; Stage II Rectal Cancer AJCC v7; Stage III Rectal Cancer AJCC v7 |
National Cancer Institute (NCI) |
2006-07-25 | PHASE2 |
| NCT01068327 | COMPLETED | Adenocarcinoma of the Pancreas; Stage III Pancreatic Cancer |
University of Nebraska |
2007-11-05 | PHASE1 |
| NCT00524186 | TERMINATED | Esophageal Cancer; Gastric Cancer |
Roswell Park Cancer Institute |
2007-05 | PHASE1 |
| NCT00803647 | COMPLETED | Metastatic Colorectal Cancer |
NSABP Foundation Inc |
2010-01 | PHASE2 |
| NCT00610948 | COMPLETED | Unspecified Adult Solid Tumor, Protocol Specific |
UNC Lineberger Comprehensive Cancer Center |
2008-03 | PHASE1 |
| NCT00967616 | COMPLETED | Colorectal Cancer; Neoplasms, Colorectal |
Daiichi Sankyo |
2009-09 | PHASE2 |
| NCT01418222 | COMPLETED | Colorectal Cancer |
Genentech, Inc. |
2011-09-14 | PHASE2 |
| NCT01640782 | COMPLETED | Adenocarcinoma of the Stomach; Adenocarcinoma of the Gastroesophageal Junction |
Mario Negri Institute for Pharmacological Research |
2005-02 | PHASE3 |
| NCT00499369 | TERMINATED | Recurrent Colon Cancer; Recurrent Rectal Cancer; Stage IVA Colon Cancer; Stage IVA Rectal Cancer; Stage IVB Colon Cancer; Stage IVB Rectal Cancer |
National Cancer Institute (NCI) |
2007-06 | PHASE3 |
| NCT00079274 | COMPLETED | Adenocarcinoma of the Colon; Stage III Colon Cancer |
National Cancer Institute (NCI) |
2004-02 | PHASE3 |
| NCT00262925 | TERMINATED | Recurrent Adult Acute Lymphoblastic Leukemia |
National Cancer Institute (NCI) |
2006-06 | PHASE2 |
| NCT00964080 | UNKNOWN | Gastric Adenocarcinoma; Gastroesophageal Junction Adenocarcinoma; Esophageal Adenocarcinoma |
Mebiopharm Co., Ltd |
2009-05 | PHASE1; PHASE2 |
| NCT00632268 | COMPLETED | Metastatic Gastric Cancer |
National Taiwan University Hospital |
2008-02 | PHASE2 |
| NCT00660894 | COMPLETED | Colorectal Cancer |
Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan |
2008-04 | PHASE3 |
| NCT00988897 | WITHDRAWN | Colorectal Neoplasms |
Sanofi |
2009-10 | PHASE2 |
| NCT01289821 | COMPLETED | Colorectal Neoplasms |
Bayer |
2011-02 | PHASE2 |
| NCT00303758 | COMPLETED | Pancreatic Cancer |
Federation Francophone de Cancerologie Digestive |
2005-10 | PHASE3 |
| NCT01467921 | UNKNOWN | Curatively-resected, Node-positive Esophageal Squamous Cell Carcinoma |
Samsung Medical Center |
2010-12 | PHASE2 |
| NCT00227617 | TERMINATED | Gastrointestinal Carcinoid Tumor; Islet Cell Tumor; Lung Cancer; Neoplastic Syndrome; Neuroendocrine Tumor |
University of California, San Francisco |
2005-06-08 | PHASE2; PHASE3 |
| NCT01258634 | TERMINATED | Osteosarcoma; Lung Metastases |
University of Chicago |
2010-07 | PHASE1 |
| NCT00861094 | COMPLETED | Esophageal Cancer |
UNICANCER |
2008-03 | PHASE2; PHASE3 |
| NCT01768182 | COMPLETED | Human Immunodeficiency Virus (HIV) Infection |
Hospital de Clinicas de Porto Alegre |
2009-08 | |
| NCT01270438 | WITHDRAWN | Adenocarcinoma of the Colon; Adenocarcinoma of the Rectum; Recurrent Colon Cancer; Recurrent Rectal Cancer; Stage IVA Colon Cancer; Stage IVA Rectal Cancer; Stage IVB Colon Cancer; Stage IVB Rectal Cancer |
National Cancer Institute (NCI) |
2010-12 | PHASE2 |
| NCT00138177 | COMPLETED | Recurrent Colon Cancer; Recurrent Rectal Cancer; Stage III Colon Cancer; Stage III Rectal Cancer; Stage IV Colon Cancer; Stage IV Rectal Cancer; Unspecified Adult Solid Tumor, Protocol Specific |
National Cancer Institute (NCI) |
2005-07 | PHASE1 |
| NCT01481545 | COMPLETED | Rectal Cancer |
National Cancer Institute, Naples |
2006-12 | PHASE2 |
| NCT00954512 | TERMINATED | Neoplasms |
Merck Sharp & Dohme LLC |
2009-09-25 | PHASE1; PHASE2 |
| NCT00539617 | TERMINATED | Esophageal Cancer |
University of California, San Francisco |
2007-10-05 | PHASE2 |
| NCT00660582 | COMPLETED | Metastatic Colorectal Cancer |
Per Pfeiffer |
2008-04 | PHASE2 |
| NCT01160419 | UNKNOWN | Gastric Cancer |
Ludwig-Maximilians - University of Munich |
2009-12 | PHASE2 |
| NCT00862784 | COMPLETED | Colorectal Carcinoma |
Eli Lilly and Company |
2009-04 | PHASE2 |
| NCT00354978 | COMPLETED | Colorectal Cancer |
M.D. Anderson Cancer Center |
2005-01 | PHASE2 |
| NCT00514020 | COMPLETED | Gastric Cancer |
Vanderbilt-Ingram Cancer Center |
2007-08 | PHASE2 |
| NCT00075725 | COMPLETED | Acute Lymphoblastic Leukemia; Adult B Acute Lymphoblastic Leukemia; Childhood B Acute Lymphoblastic Leukemia |
Children's Oncology Group |
2003-12-29 | PHASE3 |
| NCT00689624 | COMPLETED | Metastatic Colorectal Cancer |
University Hospital of Crete |
2007-07 | PHASE2 |
| NCT00557102 | COMPLETED | Colorectal Cancer; Metastatic Cancer |
National Cancer Institute, France |
2007-09 | PHASE2 |
| NCT00642577 | COMPLETED | Colorectal Cancer |
Hoffmann-La Roche |
2007-07 | PHASE3 |
| NCT01034683 | UNKNOWN | Esophageal Carcinoma |
Taian Cancer Hospital |
2009-12 | PHASE3 |
| NCT00839111 | UNKNOWN | Colorectal Neoplasms |
Fudan University |
2008-11 | PHASE2 |
| NCT00673179 | TERMINATED | Osteosarcoma |
M.D. Anderson Cancer Center |
2008-05 | |
| NCT00975897 | COMPLETED | Colorectal Cancer |
Medical Research Council |
2009-07 | PHASE2; PHASE3 |
| NCT01227707 | COMPLETED | Colorectal Cancer |
Hoffmann-La Roche |
2005-11 | PHASE2 |
| NCT00806663 | COMPLETED | Metastatic Colorectal Cancer; Liver Metastases |
Central European Society for Anticancer Drug Research |
2008-08 | PHASE2 |
| NCT00112918 | COMPLETED | Colorectal Cancer |
Hoffmann-La Roche |
2004-12 | PHASE3 |
| NCT00112658 | COMPLETED | Pancreatic Cancer |
UNICANCER |
2004-11 | PHASE2; PHASE3 |
| NCT00467142 | COMPLETED | Colorectal Cancer |
Institut Bergonié |
2007-01-23 | PHASE2 |
| NCT00399035 | COMPLETED | Metastatic Colorectal Cancer |
AstraZeneca |
2006-11 | PHASE3 |
| NCT00449163 | TERMINATED | Colorectal Cancer |
University of Miami |
2006-03-01 | PHASE2 |
| NCT00457691 | COMPLETED | Metastatic Colorectal Cancer |
Pfizer |
2007-06 | PHASE3 |
| NCT00786643 | COMPLETED | Colorectal Cancer |
Accelerated Community Oncology Research Network |
2006-02 | PHASE2 |
| NCT00003298 | COMPLETED | Gastric Cancer |
ECOG-ACRIN Cancer Research Group |
1999-06-01 | PHASE2 |
| NCT00541112 | TERMINATED | Colorectal Cancer |
UNICANCER |
2007-10-29 | PHASE2 |
| NCT00559455 | COMPLETED | Carcinoma, Hepatocellular |
Sanofi |
2007-09 | PHASE2 |
| NCT00507585 | COMPLETED | Liver Cancer; Advanced Solid Tumors |
M.D. Anderson Cancer Center |
2006-06 | PHASE1 |
| NCT00612586 | COMPLETED | Colorectal Cancer |
Eli Lilly and Company |
2008-02 | PHASE2 |
| NCT00448682 | TERMINATED | Gastric Cancer |
University of Miami |
2005-06 | PHASE2 |
| NCT00831181 | COMPLETED | Colorectal Cancer |
Beth Israel Medical Center |
2004-07 | PHASE2 |
| NCT00494221 | COMPLETED | Metastatic Colorectal Cancer |
AstraZeneca |
2007-06 | PHASE1; PHASE2 |
| NCT00057811 | COMPLETED | Childhood Burkitt Lymphoma; Childhood Diffuse Large Cell Lymphoma; Childhood Immunoblastic Large Cell Lymphoma; Stage I Childhood Large Cell Lymphoma; Stage I Childhood Small Noncleaved Cell Lymphoma; Stage II Childhood Large Cell Lymphoma; Stage II Childhood Small Noncleaved Cell Lymphoma; Stage III Childhood Large Cell Lymphoma; Stage III Childhood Small Noncleaved Cell Lymphoma; Stage IV Childhood Large Cell Lymphoma; Stage IV Childhood Small Noncleaved Cell Lymphoma; Untreated Childhood Acute Lymphoblastic Leukemia |
Children's Oncology Group |
2004-06 | PHASE2 |
| NCT00201396 | COMPLETED | Nasopharyngeal Carcinoma |
National Health Research Institutes, Taiwan |
2003-08 | PHASE3 |
| NCT00884767 | UNKNOWN | Chemotherapeutic Agent Toxicity; Colorectal Cancer; Neurotoxicity |
Institut Cancerologie de l'Ouest |
2007-09 | PHASE2 |
| NCT01271166 | TERMINATED | Advanced Colorectal Cancer |
Novartis Pharmaceuticals |
2007-10 | PHASE1 |
| NCT00634504 | COMPLETED | Osteosarcoma; Leukemia; Lymphoma |
BTG International Inc. |
2008-05 | PHASE1 |
| NCT00602329 | TERMINATED | Colorectal Cancer |
Abramson Cancer Center at Penn Medicine |
2006-02 | PHASE2 |
| NCT00631410 | COMPLETED | Colorectal Neoplasms |
Pfizer |
2008-01 | PHASE1 |
| NCT00508404 | COMPLETED | Metastatic Colorectal Cancer |
Amgen |
2007-05-09 | PHASE2 |
| NCT00422864 | COMPLETED | Rectal Cancer |
Peter MacCallum Cancer Centre, Australia |
2006-10 | PHASE2 |
| NCT00508872 | TERMINATED | Colorectal Liver Metastases |
M.D. Anderson Cancer Center |
2005-11 | PHASE2 |
| NCT00408551 | UNKNOWN | Colorectal Cancer; Metastatic Cancer |
Goshen Health System |
2005-11 | PHASE2 |
| NCT00182715 | UNKNOWN | Colorectal Cancer |
Velindre NHS Trust |
2005-03 | PHASE3 |
| NCT00080990 | COMPLETED | Unspecified Adult Solid Tumor, Protocol Specific |
National Cancer Institute (NCI) |
2004-02 | PHASE1 |
| NCT00352755 | TERMINATED | Peritoneal Neoplasms |
Washington University School of Medicine |
2006-05 | PHASE2 |
| NCT00308516 | COMPLETED | Rectal Cancer; Cancer of the Rectum; Colorectal Cancer |
SCRI Development Innovations, LLC |
2006-03 | PHASE2 |
| NCT00096278 | COMPLETED | Colon Adenocarcinoma; Stage IIA Colon Cancer AJCC v7; Stage IIB Colon Cancer AJCC v7; Stage IIC Colon Cancer AJCC v7; Stage IIIA Colon Cancer AJCC v7; Stage IIIB Colon Cancer AJCC v7; Stage IIIC Colon Cancer AJCC v7 |
National Cancer Institute (NCI) |
2004-09-15 | PHASE3 |
| NCT00634322 | TERMINATED | Osteosarcoma |
BTG International Inc. |
2008-10 | PHASE2 |
| NCT00042874 | COMPLETED | Unspecified Adult Solid Tumor, Protocol Specific |
National Cancer Institute (NCI) |
2002-05 | PHASE1 |
| NCT00618501 | COMPLETED | Leukemia |
Asan Medical Center |
2005-10 | PHASE2 |
| NCT00176462 | COMPLETED | Acute Lymphocytic Leukemia |
Rutgers, The State University of New Jersey |
2001-02 | PHASE2 |
| NCT00296608 | COMPLETED | Colorectal Cancer |
Federation Francophone de Cancerologie Digestive |
1993-04 | PHASE3 |
| NCT00423696 | COMPLETED | Colorectal Cancer |
UNICANCER |
2006-03-23 | PHASE2 |
| NCT00193219 | COMPLETED | Colon Cancer |
SCRI Development Innovations, LLC |
2005-07 | PHASE2 |
| NCT01851941 | COMPLETED | Advanced Gastric Cancer |
Seoul National University Hospital |
2004-10 | PHASE2 |
| NCT00003728 | UNKNOWN | Leukemia; Lymphoma |
European Organisation for Research and Treatment of Cancer - EORTC |
1998-12 | PHASE3 |
| NCT00500292 | COMPLETED | Colorectal; Cancer |
Genzyme, a Sanofi Company |
2007-03 | PHASE2 |
| NCT00235898 | COMPLETED | Colon Cancer; Rectal Cancer |
Mast Therapeutics, Inc. |
2005-05 | PHASE2 |
| NCT00381862 | COMPLETED | Colorectal Cancer; Nausea and Vomiting |
OHSU Knight Cancer Institute |
2006-06 | PHASE2 |
| NCT00143403 | COMPLETED | Colorectal Neoplasms; Liver Neoplasms |
Pfizer |
2001-12 | PHASE3 |
| NCT00393822 | COMPLETED | Colon Cancer |
Amgen |
2005-08 | PHASE2; PHASE3 |
| NCT00061945 | COMPLETED | Acute Undifferentiated Leukemia; B-cell Adult Acute Lymphoblastic Leukemia; B-cell Childhood Acute Lymphoblastic Leukemia; L1 Adult Acute Lymphoblastic Leukemia; L1 Childhood Acute Lymphoblastic Leukemia; L2 Adult Acute Lymphoblastic Leukemia; L2 Childhood Acute Lymphoblastic Leukemia; Philadelphia Chromosome Negative Adult Precursor Acute Lymphoblastic Leukemia; Philadelphia Chromosome Positive Adult Precursor Acute Lymphoblastic Leukemia; Philadelphia Chromosome Positive Childhood Precursor Acute Lymphoblastic Leukemia; T-cell Adult Acute Lymphoblastic Leukemia; T-cell Childhood Acute Lymphoblastic Leukemia; Untreated Adult Acute Lymphoblastic Leukemia; Untreated Childhood Acute Lymphoblastic Leukemia |
National Cancer Institute (NCI) |
2003-06 | PHASE1; PHASE2 |
| NCT00041132 | COMPLETED | Lymphoma |
SWOG Cancer Research Network |
2002-09 | PHASE2 |
| NCT00005945 | COMPLETED | Leukemia |
Children's Oncology Group |
2000-06 | PHASE3 |
| NCT00056030 | COMPLETED | Colorectal Cancer; Metastatic Cancer |
Alliance for Clinical Trials in Oncology |
2004-12 | PHASE2 |
| NCT00003925 | COMPLETED | Unspecified Adult Solid Tumor, Protocol Specific |
Barbara Ann Karmanos Cancer Institute |
1998-05 | PHASE1 |
| NCT00004897 | TERMINATED | Esophageal Cancer |
Northwestern University |
1999-10 | PHASE2 |
| NCT00005585 | COMPLETED | Leukemia |
Children's Oncology Group |
2000-04 | PHASE3 |
| NCT00692315 | COMPLETED | Autistic Disorder |
Arkansas Children's Hospital Research Institute |
2006-09 | |
| NCT00043004 | TERMINATED | Colorectal Cancer; Metastatic Cancer |
European Organisation for Research and Treatment of Cancer - EORTC |
2002-05 | PHASE2 |
| NCT00119301 | COMPLETED | Sarcoma |
Memorial Sloan Kettering Cancer Center |
2005-04 | PHASE1 |
| NCT00025337 | COMPLETED | Adenocarcinoma of the Colon; Adenocarcinoma of the Rectum; Recurrent Colon Cancer; Recurrent Rectal Cancer; Stage III Colon Cancer; Stage III Rectal Cancer; Stage IV Colon Cancer; Stage IV Rectal Cancer |
National Cancer Institute (NCI) |
2001-09 | PHASE3 |
| NCT00070122 | TERMINATED | Adenocarcinoma of the Colon; Adenocarcinoma of the Rectum; Recurrent Colon Cancer; Recurrent Rectal Cancer; Stage III Colon Cancer; Stage III Rectal Cancer; Stage IV Colon Cancer; Stage IV Rectal Cancer |
National Cancer Institute (NCI) |
2004-04 | PHASE3 |
| NCT00056446 | COMPLETED | Colorectal Neoplasms; Colonic Neoplasms; Rectal Neoplasms |
Novartis Pharmaceuticals |
2003-01 | PHASE3 |
| NCT00098982 | COMPLETED | Colorectal Cancer |
European Organisation for Research and Treatment of Cancer - EORTC |
2004-09 | PHASE1 |
| NCT00004233 | COMPLETED | Esophageal Cancer; Gastric Cancer |
SWOG Cancer Research Network |
2001-02 | PHASE2 |
| NCT00002463 | COMPLETED | Brain and Central Nervous System Tumors |
M.D. Anderson Cancer Center |
1989-02 | PHASE2 |
| NCT00183911 | COMPLETED | Gastric Adenocarcinoma; Gastric Cancer |
University of Southern California |
2003-11 | PHASE2 |
| NCT00019864 | TERMINATED | Cardiac Toxicity; Sarcoma |
National Cancer Institute (NCI) |
2000-03 | PHASE2 |
| NCT00020943 | COMPLETED | Lymphoma |
Alliance for Clinical Trials in Oncology |
2001-06 | PHASE2 |
| NCT00139230 | COMPLETED | Squamous Cell Carcinoma; Carcinoma of Head/Neck |
Dana-Farber Cancer Institute |
1997-01 | PHASE2 |
| NCT00026364 | COMPLETED | Colorectal Cancer |
National Cancer Institute (NCI) |
2001-11 | PHASE1 |
| NCT00077233 | TERMINATED | Colorectal Cancer |
Alliance for Clinical Trials in Oncology |
2003-12 | PHASE3 |
| NCT00005036 | COMPLETED | Mucinous Adenocarcinoma of the Colon; Mucinous Adenocarcinoma of the Rectum; Recurrent Colon Cancer; Recurrent Rectal Cancer; Signet Ring Adenocarcinoma of the Colon; Signet Ring Adenocarcinoma of the Rectum; Stage IIIA Colon Cancer; Stage IIIA Rectal Cancer; Stage IIIB Colon Cancer; Stage IIIB Rectal Cancer; Stage IIIC Colon Cancer; Stage IIIC Rectal Cancer; Stage IVA Colon Cancer; Stage IVA Rectal Cancer; Stage IVB Colon Cancer; Stage IVB Rectal Cancer |
National Cancer Institute (NCI) |
1999-11 | PHASE3 |
| NCT00199797 | COMPLETED | Colorectal Cancer |
Ludwig Institute for Cancer Research |
2005-04-18 | PHASE1 |
| NCT00090025 | TERMINATED | Biliary Tract Cancer |
Helsinn Healthcare SA |
2004-09 | PHASE3 |
| NCT00106054 | TERMINATED | Colorectal Neoplasms; Liver Neoplasms |
Pfizer |
2006-01 | PHASE2 |
| NCT00004231 | COMPLETED | Lymphoma |
Northwestern University |
1999-10 | PHASE2 |
| NCT00263354 | COMPLETED | Stomach Neoplasms |
Sanofi |
2003-10 | PHASE2 |
| NCT00166465 | COMPLETED | Locally Advanced Unresectable or Stage IV Colorectal Cancer |
Mayo Clinic |
2003-08 | PHASE1; PHASE2 |
| NCT00002738 | COMPLETED | Leukemia; Lymphoma; Sarcoma |
Memorial Sloan Kettering Cancer Center |
1996-01 | PHASE2 |
| NCT00507091 | COMPLETED | Metastatic; Colorectal; Adenocarcinoma |
Genzyme, a Sanofi Company |
2005-08 | PHASE1 |
| NCT00021073 | COMPLETED | Unspecified Adult Solid Tumor, Protocol Specific |
National Cancer Institute (NCI) |
2001-05 | PHASE1 |
| NCT00049569 | COMPLETED | L1 Childhood Acute Lymphoblastic Leukemia; L2 Childhood Acute Lymphoblastic Leukemia; Non-T, Non-B Childhood Acute Lymphoblastic Leukemia; Recurrent Childhood Acute Lymphoblastic Leukemia; T-cell Childhood Acute Lymphoblastic Leukemia |
National Cancer Institute (NCI) |
2003-01 | |
| NCT00002716 | COMPLETED | Colorectal Cancer; Metastatic Cancer |
Alliance for Clinical Trials in Oncology |
1996-01 | PHASE3 |
| NCT00126256 | COMPLETED | Colorectal Cancer; Metastasis |
Gustave Roussy, Cancer Campus, Grand Paris |
2002-02 | PHASE3 |
| NCT00139243 | COMPLETED | Squamous Cell Carcinoma; Carcinoma of Head and/or Neck |
Dana-Farber Cancer Institute |
1997-10 | PHASE1; PHASE2 |
| NCT00233623 | WITHDRAWN | Metastatic Colorectal Cancer |
AstraZeneca |
2004-07 | PHASE2 |
| NCT00069095 | COMPLETED | Colorectal Cancer |
Hoffmann-La Roche |
2003-07 | PHASE3 |
| NCT00416767 | COMPLETED | Gastrointestinal Carcinoid Tumor; Islet Cell Tumor; Neoplastic Syndrome |
Federation Francophone de Cancerologie Digestive |
2004-05 | PHASE2 |
| NCT00416819 | COMPLETED | Brain and Central Nervous System Tumors; Lymphoma |
University of California, San Francisco |
2003-09 | |
| NCT00066274 | COMPLETED | Colorectal Cancer |
UNICANCER |
2002-07-23 | PHASE2 |
| NCT00023998 | COMPLETED | Metastatic Osteosarcoma |
National Cancer Institute (NCI) |
2001-07 | PHASE2 |
| NCT00004005 | COMPLETED | Carcinoma of Unknown Primary; Colorectal Cancer; Unspecified Adult Solid Tumor, Protocol Specific; Unspecified Childhood Solid Tumor, Protocol Specific |
St. Jude Children's Research Hospital |
1998-09 | PHASE2 |
| NCT00003049 | COMPLETED | Pancreatic Cancer |
Mayo Clinic |
1997-05 | PHASE3 |
| NCT00103103 | TERMINATED | Gastric Cancer |
California Cancer Consortium |
2005-03 | PHASE2 |
| NCT00039208 | COMPLETED | Colorectal Cancer |
European Organisation for Research and Treatment of Cancer - EORTC |
2002-02 | PHASE2 |
| NCT00005596 | COMPLETED | Leukemia |
Children's Oncology Group |
2000-04 | PHASE3 |
| NCT00080951 | COMPLETED | Colorectal Cancer |
Alliance for Clinical Trials in Oncology |
2004-03 | PHASE2 |
| NCT00055822 | COMPLETED | Colorectal Cancer |
The University of Texas Health Science Center at San Antonio |
2002-10 | PHASE1; PHASE2 |
| NCT00003594 | COMPLETED | Colorectal Cancer |
Alliance for Clinical Trials in Oncology |
1998-10 | PHASE3 |
| NCT00002704 | COMPLETED | Leukemia |
National Cancer Institute (NCI) |
1996-01 | PHASE2 |
| NCT00023751 | COMPLETED | Colorectal Cancer |
Alliance for Clinical Trials in Oncology |
2001-07 | PHASE2 |
| NCT00002700 | COMPLETED | Leukemia; Lymphoma |
European Organisation for Research and Treatment of Cancer - EORTC |
1995-08 | PHASE3 |
| NCT00002494 | COMPLETED | Leukemia; Lymphoma |
Alliance for Clinical Trials in Oncology |
1992-05 | PHASE2 |
| NCT00065117 | TERMINATED | Colorectal Neoplasms; Metastases, Neoplasm |
AstraZeneca |
2003-09 | PHASE2 |
| NCT00002801 | COMPLETED | Colorectal Cancer |
Memorial Sloan Kettering Cancer Center |
1996-04 | PHASE1 |
| NCT00037102 | COMPLETED | Multiple Sclerosis |
MidAmerica Neuroscience Research Foundation at Rowe Neurology Institute |
2001-07 | PHASE4 |
| NCT00587873 | COMPLETED | Hodgkin's Disease |
Memorial Sloan Kettering Cancer Center |
1994-03 | PHASE2 |
| NCT00877227 | COMPLETED | Mild Hyperhomocysteinemia |
Radboud University Medical Center |
2003-01 | PHASE1 |
| NCT00003799 | COMPLETED | Adenocarcinoma of the Rectum; Mucinous Adenocarcinoma of the Rectum; Signet Ring Adenocarcinoma of the Rectum; Stage IIA Rectal Cancer; Stage IIB Rectal Cancer; Stage IIC Rectal Cancer; Stage IIIA Rectal Cancer; Stage IIIB Rectal Cancer; Stage IIIC Rectal Cancer |
National Cancer Institute (NCI) |
1999-05 | PHASE1 |
| NCT00782041 | TERMINATED | Uterine Neoplasms |
Sanofi |
2003-01 | PHASE2 |
| NCT00002471 | COMPLETED | Leukemia; Lymphoma |
Memorial Sloan Kettering Cancer Center |
1990-02 | PHASE2 |
| NCT00037115 | WITHDRAWN | Demyelinating Disorders; Multiple Sclerosis; Optic Neuritis; Myelitis; Neuritis |
MidAmerica Neuroscience Research Foundation at Rowe Neurology Institute |
2002-05 | PHASE4 |
| NCT00002816 | COMPLETED | Leukemia |
Children's Oncology Group |
1996-12 | PHASE3 |
| NCT00003671 | COMPLETED | Leukemia |
Children's Oncology Group |
1998-12 | PHASE2 |
| NCT00004913 | COMPLETED | Unspecified Adult Solid Tumor, Protocol Specific |
Northwestern University |
2000-01 | PHASE1 |
| NCT00006103 | COMPLETED | Colorectal Cancer |
Alliance for Clinical Trials in Oncology |
2000-07 | PHASE3 |
| NCT00003287 | COMPLETED | Colorectal Cancer |
European Organisation for Research and Treatment of Cancer - EORTC |
1998-03 | PHASE3 |
| NCT00003018 | COMPLETED | Pancreatic Cancer |
SWOG Cancer Research Network |
1997-09 | PHASE2 |
| NCT00002665 | COMPLETED | Leukemia; Neutropenia; Thrombocytopenia |
SWOG Cancer Research Network |
1995-07 | PHASE2 |
| NCT00004102 | COMPLETED | Colorectal Cancer |
NYU Langone Health |
1999-01 | PHASE2 |
| NCT00002552 | COMPLETED | Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm |
Barbara Ann Karmanos Cancer Institute |
1993-10 | PHASE2 |
| NCT00004885 | COMPLETED | Colorectal Cancer |
European Organisation for Research and Treatment of Cancer - EORTC |
1999-07 | PHASE3 |
| NCT00021398 | COMPLETED | Colorectal Cancer |
Fox Chase Cancer Center |
1996-07 | PHASE2 |
| NCT00005988 | COMPLETED | Graft Versus Host Disease; Leukemia; Lymphoma; Myelodysplastic Syndromes; Myeloma |
Dana-Farber Cancer Institute |
2000-02 | PHASE1 |
| NCT00002783 | COMPLETED | Gastric Cancer |
Memorial Sloan Kettering Cancer Center |
1996-05 | PHASE2 |
| NCT00002618 | COMPLETED | Lymphoma |
Children's Oncology Group |
1994-12 | PHASE3 |
| NCT00002691 | COMPLETED | Lymphoma |
Memorial Sloan Kettering Cancer Center |
1995-08 | PHASE2 |
| NCT00002955 | COMPLETED | Pancreatic Cancer |
University of Southern California |
1995-08 | PHASE2 |
| NCT00003776 | COMPLETED | Sarcoma |
Memorial Sloan Kettering Cancer Center |
1998-12 | PHASE2 |
| NCT00002593 | COMPLETED | Colorectal Cancer |
SWOG Cancer Research Network |
1994-12 | PHASE3 |
| NCT00002722 | COMPLETED | Gastric Cancer |
European Organisation for Research and Treatment of Cancer - EORTC |
1996-01 | PHASE2 |
| NCT00425152 | COMPLETED | Colorectal Cancer |
NSABP Foundation Inc |
1989-07 | PHASE3 |
| NCT00002002 | COMPLETED | Pneumonia, Pneumocystis Carinii; HIV Infections |
Lederle Laboratories |
||
| NCT00220064 | COMPLETED | Upper Gastrointestinal Tumours |
Royal Marsden NHS Foundation Trust |
2000-07 | PHASE2 |
| NCT00300404 | COMPLETED | Schizophrenia; Major Depression |
Zentrum für Integrative Psychiatrie |
2002-01 | PHASE3 |
| NCT00002531 | UNKNOWN | Leukemia |
Johann Wolfgang Goethe University Hospital |
1993-01 | PHASE2 |
| NCT00042861 | COMPLETED | Unspecified Adult Solid Tumor, Protocol Specific |
National Cancer Institute (NCI) |
2002-08 | PHASE1 |
| NCT00294593 | COMPLETED | Down Syndrome |
Institut Jerome Lejeune |
2000-10 | PHASE2; PHASE3 |
| NCT00027833 | UNKNOWN | Colorectal Cancer |
Herbert Irving Comprehensive Cancer Center |
2001-12 | PHASE2 |
| NCT00212589 | COMPLETED | Colorectal Cancer |
Odense University Hospital |
2002-12 | PHASE3 |
| NCT00004997 | COMPLETED | 5q Minus Syndrome; Myelodysplastic Syndrome |
National Institutes of Health Clinical Center (CC) |
1998-04 | PHASE2 |
| NCT00003260 | UNKNOWN | Colorectal Cancer |
GERCOR - Multidisciplinary Oncology Cooperative Group |
1998-01 | PHASE3 |
| NCT00323011 | TERMINATED | Colorectal Cancer |
University of Southern California |
2006-05 | PHASE2 |
| NCT00009828 | WITHDRAWN | Unspecified Adult Solid Tumor, Protocol Specific |
University of Pittsburgh |
1999-12 | PHASE1 |
| NCT00385021 | TERMINATED | Colorectal Neoplasms |
Southwestern Regional Medical Center |
2006-10 | PHASE2 |
| NCT00006112 | UNKNOWN | Carcinoma of the Appendix; Colorectal Cancer; Primary Peritoneal Cavity Cancer |
Gustave Roussy, Cancer Campus, Grand Paris |
1996-01 | PHASE2 |
| NCT00611507 | COMPLETED | Stomach Neoplasms |
Sanofi |
2002-11 | PHASE2 |
| NCT00005860 | COMPLETED | Cancer |
Memorial Sloan Kettering Cancer Center |
2000-04 | PHASE1 |
| NCT00046995 | UNKNOWN | Colorectal Cancer |
Groupe Regional d'Etudes du Cancer Colorectal |
2001-05 | PHASE3 |
| NCT00004164 | UNKNOWN | Head and Neck Cancer |
Dana-Farber Cancer Institute |
1999-08 | PHASE2 |
| NCT00003273 | WITHDRAWN | Brain and Central Nervous System Tumors; Neuroblastoma; Retinoblastoma; Sarcoma |
NYU Langone Health |
1997-11 | PHASE2 |
| NCT00008281 | UNKNOWN | Colorectal Cancer |
Sanofi |
2000-10 | PHASE3 |
| NCT00072553 | UNKNOWN | Colorectal Cancer |
GERCOR - Multidisciplinary Oncology Cooperative Group |
2003-09 | PHASE2 |
| NCT00020488 | COMPLETED | Unspecified Adult Solid Tumor, Protocol Specific |
National Cancer Institute (NCI) |
2001-02 | PHASE1 |
| NCT00001579 | COMPLETED | Lymphoma; Neoplasms |
National Cancer Institute (NCI) |
1997-06 | PHASE1 |
| NCT00019760 | COMPLETED | Recurrent Colon Cancer; Liver Metastases; Stage IV Rectal Cancer; Recurrent Rectal Cancer; Stage IV Colon Cancer |
National Institutes of Health Clinical Center (CC) |
1999-04 | PHASE2 |
| NCT00002102 | COMPLETED | Pneumonia, Pneumocystis Carinii; HIV Infections |
U.S. Bioscience |
||
| NCT00513266 | UNKNOWN | Colorectal Cancer; Metastatic Cancer |
Centre Hospitalier Universitaire Vaudois |
2007-06 | PHASE2 |
| NCT00037089 | UNKNOWN | Esophageal Neoplasm |
Edelman, Martin, M.D. |
PHASE2 | |
| NCT00000714 | COMPLETED | Pneumonia, Pneumocystis Carinii; HIV Infections |
National Institute of Allergy and Infectious Diseases (NIAID) |
PHASE3 | |
| NCT00047762 | COMPLETED | Colorectal Cancer |
Genentech, Inc. |
2002-10 | PHASE1 |
| NCT00154778 | COMPLETED | Gastric Cancer |
National Taiwan University Hospital |
2003-03 | PHASE2 |
| NCT00005586 | COMPLETED | Colorectal Cancer |
Institute of Cancer Research, United Kingdom |
1997-10 | PHASE3 |
| NCT00001338 | COMPLETED | Breast Neoplasms; Fever; Hematologic Diseases; Neutropenia; Sepsis |
National Cancer Institute (NCI) |
1993-06 | PHASE3 |
| NCT00274872 | UNKNOWN | Colorectal Cancer |
GERCOR - Multidisciplinary Oncology Cooperative Group |
2004-01 | PHASE2; PHASE3 |
| NCT00016133 | COMPLETED | Colorectal Cancer |
Intracel |
2001-03 | PHASE1; PHASE2 |
| NCT00201305 | COMPLETED | Biliary Tract Disease |
National Health Research Institutes, Taiwan |
2002-07 | PHASE2 |
| NCT00019513 | COMPLETED | Colorectal Cancer; Esophageal Cancer; Extrahepatic Bile Duct Cancer; Gallbladder Cancer; Liver Cancer; Lung Cancer; Lymphoma; Pancreatic Cancer; Small Intestine Cancer; Unspecified Adult Solid Tumor, Protocol Specific |
National Institutes of Health Clinical Center (CC) |
1998-08 | PHASE1 |
| NCT00000724 | COMPLETED | Pneumonia, Pneumocystis Carinii; HIV Infections |
National Institute of Allergy and Infectious Diseases (NIAID) |
PHASE3 | |
| NCT00002532 | UNKNOWN | Leukemia |
Hannover Medical School |
1993-01 | PHASE2 |
| NCT00081536 | UNKNOWN | Colorectal Neoplasms |
Aronex Pharmaceuticals |
PHASE1; PHASE2 | |
| NCT00002120 | COMPLETED | Pneumonia, Pneumocystis Carinii; HIV Infections |
U.S. Bioscience |
PHASE1 | |
| NCT00155883 | TERMINATED | Gastric Cancer |
National Taiwan University Hospital |
2004-06 | PHASE2 |
| NCT00088270 | COMPLETED | Locally Advanced or Metastatic Adenoca of the Biliary Tract |
OSI Pharmaceuticals |
2004-08 | PHASE2 |
| NCT00025142 | COMPLETED | Colorectal Cancer |
Stanford University |
2001-07 | PHASE2 |
| NCT00201344 | TERMINATED | Nasopharyngeal Carcinoma |
National Health Research Institutes, Taiwan |
1994-11 | PHASE3 |
| NCT00079872 | COMPLETED | Colorectal Cancer |
Eli Lilly and Company |
2004-02 | PHASE2 |
| NCT00004150 | COMPLETED | Colorectal Cancer |
Robert Roessle Klinik |
1999-03 | PHASE3 |
| NCT00001016 | COMPLETED | Pneumonia, Pneumocystis Carinii; HIV Infections |
National Institute of Allergy and Infectious Diseases (NIAID) |
PHASE3 | |
| NCT00309543 | COMPLETED | Colon Cancer Stage II |
Austrian Breast & Colorectal Cancer Study Group |
1993-11 | PHASE3 |
| NCT00000658 | COMPLETED | Lymphoma, Non-Hodgkin; HIV Infections |
National Institute of Allergy and Infectious Diseases (NIAID) |
PHASE3 | |
| NCT00003001 | UNKNOWN | Colorectal Cancer |
Stony Brook University |
1997-04 | PHASE1; PHASE2 |
| NCT00323583 | UNKNOWN | Adenocarincoma of Pancreas; Stage III Pancreatic Cancer; Stage IVA Pancreatic Cancer; Stage IVB Pancreatic Cancer |
Seattle Cancer Treatment and Wellness Center |
2006-05 | PHASE2 |
| NCT00000973 | COMPLETED | Toxoplasmosis, Cerebral; HIV Infections |
National Institute of Allergy and Infectious Diseases (NIAID) |
PHASE1 | |
| NCT00001269 | COMPLETED | Breast Neoplasms; Neoplasm Metastasis |
National Cancer Institute (NCI) |
1991-05 | PHASE1 |
| NCT00313859 | COMPLETED | Colorectal Cancer; Metastasis |
Samsung Medical Center |
2005-09 | PHASE2 |
| NCT00237900 | TERMINATED | Subjects With Resectable Local or Locally Advanced, Non-Metastatic (T2-T4, N0-N3, M0; Stages II and III) and Histologically-Confirmed Intestinal GC |
AstraZeneca |
2003-07 | PHASE1; PHASE2 |
| NCT00276757 | COMPLETED | Childhood Langerhans Cell Histiocytosis |
Histiocyte Society |
2001-04 | |
| NCT00020501 | COMPLETED | Colorectal Cancer; Metastatic Cancer |
National Institutes of Health Clinical Center (CC) |
2001-03 | PHASE3 |
| NCT00149578 | UNKNOWN | Pancreatic Cancer |
National Health Research Institutes, Taiwan |
2004-10 | PHASE2 |
| NCT00078468 | COMPLETED | Colorectal Neoplasms |
Pfizer |
2003-12 | PHASE2 |
(data from https://clinicaltrials.gov, updated on 2026-06-18)
Check the
Leucovorin Calcium Pentahydrate (Folinic acid)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Mechanism and Biochemical Profile
Appendix RUO and cGMP Quality Standards
| Quality Dimension | RUO (Research Use Only) | cGMP (Current Good Manufacturing Practice) |
|---|---|---|
| Clinical Applicability | Prohibited in human clinical trials or medical diagnostics. | Mandatory for human clinical trials (Phase I–III) and therapies. |
| Regulatory Status | Non-regulated grade; exempt from drug manufacturing laws. | Legally enforced by health authorities (e.g., FDA, EMA, NMPA). |
| Facility Environment | Unclassified analytical or research laboratories. | Validated Cleanrooms (ISO Class 5–8) with continuous monitoring. |
| Quality Control | Basic purity and activity testing. | Rigorous safety release testing (Sterility, Endotoxin, Mycoplasma). |
| Process Validation | Basic equipment calibration; no process validation required. | Full qualification (IQ/OQ/PQ) and complete batch records. |
| Quality Assurance | Vendor self-declared without required formal QMS. | Mandatory QA/QC unit, Change Control, CAPA, and vendor audits. |
| Regulatory Impact | High risk of IND rejection if used as a critical raw material. | Required for IND/NDA filings, supported by Drug Master Files (DMF). |
Footnotes
Regulatory Note: Governed by FDA (21 CFR Parts 210/211/312), EMA (EudraLex Vol 4), ICH Guidelines (E6/Q7/Q9/Q10), and compendial standards (USP <71>/<85>/<1043>).
- Leucovorin Calcium Pentahydrate (Folinic acid) Solubility in DMSO
- Leucovorin Calcium Pentahydrate (Folinic acid) Storage
- Leucovorin Calcium Pentahydrate (Folinic acid) Stability
- Leucovorin Calcium Pentahydrate (Folinic acid) Molecular Weight
- Leucovorin Calcium Pentahydrate (Folinic acid) SMILES
- Leucovorin Calcium Pentahydrate (Folinic acid) CAS Number
- Leucovorin Calcium Pentahydrate (Folinic acid) Chemical Structure (2D and 3D)
- Leucovorin Calcium Pentahydrate (Folinic acid) SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.