CAS No. 103577-45-3

Batch: Purity:99.34
Lansoprazole Chemical Structure
Chemical Structure
Check the Lansoprazole product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name 2-[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methylsulfinyl]-1H-benzimidazole
CAS Number 103577-45-3
Molecular Formula

C16H14F3N3O2S

Molecular Weight (MW) 369.36
SMILES CC1=C(C=CN=C1CS(=O)C2=NC3=CC=CC=C3N2)OCC(F)(F)F
InChIKey MJIHNNLFOKEZEW-UHFFFAOYSA-N

Ordering Information

Biological Activity

Lansoprazole is a proton-pump inhibitor that covalently binds to and inactivates the gastric H+/K+-ATPase enzyme system. By blocking this final step of hydrogen ion secretion in stomach parietal cells, lansoprazole suppresses both basal and stimulated gastric acid production. This potent antisecretory activity elevates intragastric pH, preventing acid-induced cellular damage and maintaining mucosal epithelial integrity. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 74 mg/mL (200.34 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 14 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.