Clinical Trials

Itraconazole has been evaluated across numerous clinical trials spanning Early Phase 1 through Phase 4, addressing fungal infections in HIV patients, solid tumors, and drug-drug interactions in healthy volunteers. Prominently supported by pharmaceutical developers and institutional sponsors, research ranges from completed pivotal studies to actively recruiting Phase 1 and Phase 2 trials evaluating pharmacokinetic modulation and oncologic efficacy.

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT07261150 NOT_YET_RECRUITING
Histoplasmosis
University of Minnesota
2026-09-15 PHASE3
NCT07283497 RECRUITING
Bronchiectasis; Fungal Infection of Upper Respiratory Tract
Mayo Clinic
2026-08-17 PHASE4
NCT06732388 RECRUITING
Barrett Esophagus; Clinical Stage I Esophageal Adenocarcinoma AJCC v8; Clinical Stage IIA Esophageal Adenocarcinoma AJCC v8; Esophageal Adenocarcinoma
National Cancer Institute (NCI)
2026-06-23 PHASE2
NCT06400472 RECRUITING
Ovarian Neoplasms; Endometrial Neoplasms; Uterine Cervical Neoplasms; Carcinoma, Non-Small-Cell Lung; Triple Negative Breast Neoplasms; Pancreatic Neoplasm; Colorectal Neoplasms
Eli Lilly and Company
2024-05-20 PHASE1
NCT05563766 RECRUITING
Esophageal Adenocarcinoma; Esophageal Squamous Cell Carcinoma; Gastroesophageal Junction Carcinoma
VA Office of Research and Development
2024-10-01 PHASE2
NCT04067336 ACTIVE_NOT_RECRUITING
Advanced Malignant Neoplasm; Acute Myeloid Leukemia; Mixed Lineage Leukemia; Mixed Lineage Acute Leukemia; Acute Leukemia of Ambiguous Lineage; Mixed Phenotype Acute Leukemia; Acute Lymphoblastic Leukemia
Kura Oncology, Inc.
2019-09-12 PHASE1; PHASE2
NCT03460977 RECRUITING
Metastatic Castration Resistant Prostate Cancer (mCRPC); Small Cell Lung Cancer (SCLC); Follicular Lymphoma (FL)
Pfizer
2018-04-17 PHASE1
NCT07070232 RECRUITING
Advanced Solid Tumor
BioNTech SE
2025-08-12 PHASE1; PHASE2
NCT05914116 RECRUITING
Advanced Solid Tumors
DualityBio Inc.
2023-08-17 PHASE1; PHASE2
NCT05384626 RECRUITING
Locally Advanced Solid Tumor; Metastatic Solid Tumor
Nuvalent Inc.
2022-06-09 PHASE1; PHASE2
NCT07402915 RECRUITING
Fallopian Tube Cancer; Ovarian Cancer; Primary Peritoneal
AstraZeneca
2026-01-26 PHASE1
NCT06084481 RECRUITING
Hepatocellular Carcinoma; Pancreatic Ductal Adenocarcinoma; Biliary Tract Cancers; Esophageal Squamous Cell Carcinoma; Triple Negative Breast Cancer; Hormone Receptor+/Human Epidermal Growth Factor Receptor 2 Negative Breast Cancer; Head and Neck Squamous-Cell Carcinoma; Platinum Resistant High Grade Epithelial Ovarian Cancer
AbbVie
2023-11-09 PHASE1
NCT05150691 RECRUITING
HER2-positive Advanced Solid Tumor
DualityBio Inc.
2022-01-31 PHASE1; PHASE2
NCT07797478 RECRUITING
Healthy Volunteers
Genentech, Inc.
2026-08-28 PHASE1
NCT03656081 RECRUITING
Chronic Pulmonary Aspergillosis
Poitiers University Hospital
2018-12-19 PHASE3
NCT07395024 ACTIVE_NOT_RECRUITING
Healthy Volunteer
Astellas Pharma Global Development, Inc.
2026-02-03 PHASE1
NCT07341672 NOT_YET_RECRUITING
Healthy Adult Subject
Sunshine Lake Pharma Co., Ltd.
2026-12-31 PHASE1
NCT07438886 NOT_YET_RECRUITING
Healthy Volunteer
Advenchen Laboratories Nanjing Ltd.
2026-03-02 PHASE1
NCT07800897 NOT_YET_RECRUITING
Healthy Female Adults
Bristol-Myers Squibb
2026-08-26 PHASE1
NCT07675239 NOT_YET_RECRUITING
Tinea Corporis
Pak Emirates Military Hospital
2026-10-01 PHASE4
NCT07764692 NOT_YET_RECRUITING
Healthy Participants
Jiangsu Hansoh Pharmaceutical Co., Ltd.
2026-08-01 PHASE1
NCT07339722 RECRUITING
Healthy
Eli Lilly and Company
2026-01-15 PHASE1
NCT07071532 NOT_YET_RECRUITING
Bipolar Disorder
AbbVie
2026-08-21 PHASE1
NCT05444946 RECRUITING
Chronic Pulmonary Aspergillosis; Allergic Bronchopulmonary Aspergillosis
Post Graduate Institute of Medical Education and Research, Chandigarh
2022-06-15
NCT07768111 NOT_YET_RECRUITING
Drug Interaction Research
Chengdu Zenitar Biomedical Technology Co., Ltd
2026-10-30 PHASE1
NCT07620041 NOT_YET_RECRUITING
Refractory or Relapsed Solid Tumors
Qilu Pharmaceutical Co., Ltd.
2026-06-05 PHASE1
NCT06300138 RECRUITING
Sporotrichosis
First Hospital of China Medical University
2024-03-15
NCT07134465 ENROLLING_BY_INVITATION
Healthy Subjects
Haisco Pharmaceutical Group Co., Ltd.
2025-08-11 PHASE1
NCT07783503 NOT_YET_RECRUITING
Healthy Participants
Novartis Pharmaceuticals
2026-08-27 PHASE1
NCT07766369 NOT_YET_RECRUITING
Healthy Volunteers
Eisai Inc.
2026-08-12 PHASE1
NCT07775261 NOT_YET_RECRUITING
Healthy Participants
H. Lundbeck A/S
2026-08-27 PHASE1
NCT07357610 RECRUITING
Healthy Adult Participants
Jiangsu Simcere Pharmaceutical Co., Ltd.
2026-01-05 PHASE1
NCT07685600 RECRUITING
Healthy
AstraZeneca
2026-07-30 PHASE1
NCT07661108 ACTIVE_NOT_RECRUITING
Healthy
Merck Sharp & Dohme LLC
2026-06-30 PHASE1
NCT07774325 NOT_YET_RECRUITING
Healthy
Boehringer Ingelheim
2026-09-01 PHASE1
NCT03458221 RECRUITING
Recurrent Ovarian Cancer; Signal Transduction Pathway Deregulation; Therapy-Associated Cancer
Gynaecologisch Oncologisch Centrum Zuid
2023-01-31 PHASE2; PHASE3
NCT07800429 NOT_YET_RECRUITING
Healthy Participants
Vaderis Therapeutics AG
2026-09 PHASE1
NCT07590102 RECRUITING
Healthy Volunteers
BeOne Medicines
2026-06-04 PHASE1
NCT07734441 RECRUITING
Seborrheic Dermatitis
Combined Military Hospital (CMH) institute of Medical Sciences Bahawalpur Pakistan
2026-01-07 EARLY_PHASE1
NCT07599761 ACTIVE_NOT_RECRUITING
Healthy Volunteers
AbbVie
2026-05-07 PHASE1
NCT07649954 RECRUITING
Healthy Volunteer
AbbVie
2026-06-23 PHASE1
NCT07435194 ACTIVE_NOT_RECRUITING
Healthy
Merck Sharp & Dohme LLC
2026-03-06 PHASE1
NCT07186452 RECRUITING
Advanced Solid Tumors
Hansoh BioMedical R&D Company
2025-09-23 PHASE1
NCT07535970 NOT_YET_RECRUITING
Healthy Participants
Jiangsu Hansoh Pharmaceutical Co., Ltd.
2026-04-30 PHASE1
NCT06154447 COMPLETED
Cystic Fibrosis
Vertex Pharmaceuticals Incorporated
2023-12-12 PHASE1
NCT07592572 COMPLETED
Healthy
Eli Lilly and Company
2026-05-20 PHASE1
NCT06485505 RECRUITING
Onychomycosis
Zagazig University
2024-07-12 PHASE1
NCT07374224 RECRUITING
Clinical Pharmacology
Guangzhou Lupeng Pharmaceutical Company LTD.
2026-03-05 PHASE1
NCT07575945 COMPLETED
Healthy Participant
Pfizer
2026-05-05 PHASE1
NCT04018872 RECRUITING
Esophagus Adenocarcinoma; Esophagus Squamous Cell Carcinoma; Gastroesophageal Junction Adenocarcinoma
Dallas VA Medical Center
2019-06-24 PHASE2
NCT06447402 UNKNOWN
Chronic Pulmonary Aspergillosis; CPA; Aspergilloma
Post Graduate Institute of Medical Education and Research, Chandigarh
2024-06-03 PHASE3
NCT07548606 COMPLETED
Healthy
Merck Sharp & Dohme LLC
2026-05-11 PHASE1
NCT06174922 RECRUITING
Allergic Bronchopulmonary Aspergillosis
Post Graduate Institute of Medical Education and Research, Chandigarh
2023-12-01 PHASE3
NCT07550621 NOT_YET_RECRUITING
Healthy Volunteers (HV)
MindRank AI Ltd
2026-05-06 PHASE1
NCT06909162 COMPLETED
Healthy Participants
Incyte Corporation
2025-05-05 PHASE1
NCT07449390 COMPLETED
Healthy Participants
Acesion Pharma
2026-04-01 PHASE1
NCT07331792 NOT_YET_RECRUITING
Pityriasis Versicolor
Combined Military Hospital Abbottabad
2026-02-02 PHASE1; PHASE2
NCT07242781 TERMINATED
Healthy Volunteers
Celgene
2025-12-15 PHASE1
NCT07242703 NOT_YET_RECRUITING
Fungal Resistance
Cairo University
2025-12-01
NCT07429331 COMPLETED
Healthy Volunteers
Cascade Pharmaceuticals, Inc
2026-03-09 PHASE1
NCT07308652 COMPLETED
Healthy
Boehringer Ingelheim
2026-02-09 PHASE1
NCT07039877 RECRUITING
Acute Lymphobkastic Leukemia; Acute Lymphoblastic Leukaemia Recurrent; Philadelphia Chromosome Negative ALL
Hospital Universitario Dr. Jose E. Gonzalez
2025-01-02 PHASE2
NCT07335419 COMPLETED
Healthy Adult Participants
Pfizer
2026-01-02 PHASE1
NCT07342153 RECRUITING
Tinea Corporis; Dermatophytosis
Urooj Fatima
2025-11-01 PHASE4
NCT06746064 COMPLETED
Pulmonary Fibrosis
Chiesi Farmaceutici S.p.A.
2025-01-13 PHASE1
NCT06942936 COMPLETED
Healthy Participants
AstraZeneca
2025-05-28 PHASE1
NCT07211425 COMPLETED
Healthy
Boehringer Ingelheim
2025-10-08 PHASE1
NCT06698926 COMPLETED
Healthy Volunteer
AbbVie
2024-11-11 PHASE1
NCT05156892 ACTIVE_NOT_RECRUITING
Ovarian Cancer
Anthony Joshua, FRACP
2022-09-04 PHASE1
NCT07697157 COMPLETED
Health, Subjective
Hutchmed
2025-03-01 PHASE1
NCT06922344 RECRUITING
Pityriasis Versicolor
Khyber Teaching Hospital
2025-03-01 PHASE4
NCT06160713 UNKNOWN
Bronchiectasis; Bronchiectasis Adult
Post Graduate Institute of Medical Education and Research, Chandigarh
2023-12-01 PHASE3
NCT07229560 COMPLETED
Breast Cancer
Shandong Suncadia Medicine Co., Ltd.
2025-11-26 PHASE1
NCT07184203 RECRUITING
Tinea Capitis
Alexandria University
2025-03-09
NCT07066722 COMPLETED
HIV Infections
ViiV Healthcare
2025-07-07 PHASE1
NCT07160738 COMPLETED
Healthy Adults
Pfizer
2025-09-22 PHASE1
NCT06919991 COMPLETED
Healthy Participants
Arcus Biosciences, Inc.
2025-05-02 PHASE1
NCT06710990 COMPLETED
Advanced Breast Cancer
Jiangsu HengRui Medicine Co., Ltd.
2025-02-17 PHASE1
NCT06906809 COMPLETED
Healthy Volunteers
BeiGene
2025-04-03 PHASE1
NCT06701136 NOT_YET_RECRUITING
Rifampicin-Resistant Pulmonary Tuberculosis Patients
Shanghai Jiatan Pharmatech Co., Ltd
2025-05-12 PHASE1
NCT07068256 COMPLETED
Tinea Capitis
Muhammad Aamir Latif
2025-04-01
NCT07018635 COMPLETED
Healthy Participants
Incyte Corporation
2025-07-16 PHASE1
NCT06579300 TERMINATED
Healthy Volunteer
AbbVie
2024-09-04 PHASE1
NCT07056842 COMPLETED
Obesity &Amp; Overweight
Vincentage Pharma Co., Ltd
2025-07-20 PHASE1
NCT06945276 COMPLETED
COVID-19
National Institute of Allergy and Infectious Diseases (NIAID)
2025-05-13 PHASE1
NCT07420894 COMPLETED
Dermatophytosis; Trichophyton Infection; Resistant Dermatophyte Infection
Multan Medical And Dental College
2025-01-29
NCT06965881 TERMINATED
Tuberous Sclerosis Complex (TSC); Focal Cortical Dysplasia; Other Neurological Disorders
GRIN Therapeutics, Inc.
2025-05-08 PHASE1
NCT06672900 ACTIVE_NOT_RECRUITING
Healthy Volunteer
Aligos Therapeutics
2025-01-09 PHASE1
NCT06787131 COMPLETED
Healthy
Lomond Therapeutics Holdings, Inc.
2024-05-21 PHASE1
NCT07069933 NOT_YET_RECRUITING
Acute Myeloid Leukemia
Mansoura University
2025-07 PHASE2
NCT06399315 COMPLETED
AML
Lomond Therapeutics Holdings, Inc.
2023-07-28 PHASE1
NCT06809608 COMPLETED
Healthy Participants
Hoffmann-La Roche
2025-02-13 PHASE1
NCT06847464 COMPLETED
RSV Infection; Drug Drug Interaction (DDI)
Enanta Pharmaceuticals, Inc
2025-01-27 PHASE1
NCT06837142 COMPLETED
Healthy Male Subjects
Taisho Pharmaceutical Co., Ltd.
2025-03-11 PHASE1
NCT06846528 COMPLETED
Healthy Participants
AstraZeneca
2025-02-26 PHASE1
NCT06541678 COMPLETED
Healthy
Pfizer
2024-12-23 PHASE1
NCT06662773 UNKNOWN
Healthy
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2024-11 PHASE1
NCT06706869 COMPLETED
Healthy
Pfizer
2024-12-11 PHASE1
NCT06671405 COMPLETED
Dyslipidaemia
AstraZeneca
2024-09-25 PHASE1
NCT06690138 COMPLETED
Healthy Participants
Genentech, Inc.
2024-11-15 PHASE1
NCT06205381 COMPLETED
Healthy Participants
Aeovian Pharmaceuticals, Inc.
2024-01-31 PHASE1
NCT06722430 COMPLETED
Healthy Volunteer
AbbVie
2024-11-13 PHASE1
NCT06677996 COMPLETED
Healthy Volunteer
Immunome, Inc.
2024-11-11 PHASE1
NCT06597500 COMPLETED
Pulmonary Disease, Chronic Obstructive
GlaxoSmithKline
2024-09-30 PHASE1
NCT06658964 NOT_YET_RECRUITING
ADPKD (autosomal Dominant Polycystic Kidney Disease)
Jemincare
2024-11-05 PHASE1
NCT06586606 COMPLETED
Alzheimer's Disease
Merck Sharp & Dohme LLC
2024-10-03 PHASE1
NCT06562088 UNKNOWN
Healthy Adult Subject
Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd.
2024-08-16 PHASE1
NCT06619951 COMPLETED
Locally Advanced or Metastatic Solid Tumor
Jiangsu vcare pharmaceutical technology co., LTD
2024-09-18 PHASE1
NCT06362642 COMPLETED
Healthy Volunteers
PMV Pharmaceuticals, Inc
2024-03-28 PHASE1
NCT06543043 COMPLETED
Not Determined
BeiGene
2024-08-19 PHASE1
NCT06494644 COMPLETED
Healthy Participants
AstraZeneca
2024-07-23 PHASE1
NCT06492525 UNKNOWN
Healthy
Betta Pharmaceuticals Co., Ltd.
2024-07 PHASE1
NCT05591560 UNKNOWN
Ovarian Carcinoma
Tanta University
2022-10
NCT06379958 UNKNOWN
Pharmacokinetics
Modern Biosciences Ltd
2024-04-08 PHASE1
NCT06589635 COMPLETED
Healthy Adults
Jiaxing AnDiCon Biotech Co.,Ltd
2024-07-16 PHASE1
NCT06363630 COMPLETED
Healthy Volunteers
Celgene
2024-04-23 PHASE1
NCT06644326 COMPLETED
Healthy
ABLi Therapeutics, Inc.
2023-06-21 PHASE1
NCT05679388 TERMINATED
Prostate Cancer; Prostate Cancer Metastatic; Prostate Adenocarcinoma
University of Chicago
2023-02-13 PHASE1
NCT06495944 COMPLETED
Healthy Adults
Corcept Therapeutics
2024-05-31 PHASE1
NCT06406400 TERMINATED
Opioid Use Disorder
AstraZeneca
2024-05-13 PHASE1
NCT06719557 COMPLETED
Healthy
Merck Sharp & Dohme LLC
2024-05-20 PHASE1
NCT05372367 COMPLETED
Solid Tumors
Boehringer Ingelheim
2022-08-11 PHASE1
NCT06232109 COMPLETED
Drug Drug Interaction
Asceneuron S.A.
2024-02-22 PHASE1
NCT06392659 COMPLETED
Pain
Vertex Pharmaceuticals Incorporated
2024-05-02 PHASE1
NCT06344936 UNKNOWN
Chronic Kidney Disease(CKD)
Shandong Suncadia Medicine Co., Ltd.
2024-04 PHASE1
NCT06345794 COMPLETED
Healthy
DICE Therapeutics, Inc., a wholly owned subsidiary of Eli Lilly and Company
2024-04-03 PHASE1
NCT06357520 COMPLETED
Healthy Participants
AstraZeneca
2024-04-16 PHASE1
NCT06348888 COMPLETED
Advanced Non-small Cell Lung Cancer; EGFR Mutation; HER2 Mutation; Healthy Volunteers
Bayer
2024-04-10 PHASE1
NCT06332053 UNKNOWN
Healthy Subjects
Shouyao Holdings (Beijing) Co. LTD
2024-04-01 PHASE1
NCT04824417 COMPLETED
Chronic Pulmonary Aspergillosis
Post Graduate Institute of Medical Education and Research, Chandigarh
2021-03-01 PHASE3
NCT06348290 UNKNOWN
Solid Tumor, Adult
Jemincare
2024-04-01 PHASE1
NCT02675452 TERMINATED
Relapsed or Refractory Multiple Myeloma; Relapsed or Refractory Acute Myeloid Leukemia
Amgen
2016-06-13 PHASE1
NCT06170723 COMPLETED
Healthy Participants
Celgene
2024-03-18 PHASE1
NCT06255951 COMPLETED
NSCLC
TYK Medicines, Inc
2024-03-12 PHASE1
NCT06194864 COMPLETED
Drug Interaction
Emalex Biosciences Inc.
2024-01-18 PHASE1
NCT06294561 COMPLETED
Non Small Cell Lung Cancer
Shenzhen TargetRx Co., Ltd.
2024-03-04 PHASE1
NCT05563766 Not yet recruiting
Esophageal Adenocarcinoma|Esophageal Squamous Cell Carcinoma|Gastroesophageal Junction Carcinoma
VA Office of Research and Development|Durham VA Health Care System|VA Palo Alto Health Care System|Portland VA Medical Center|VA Puget Sound Health Care System|Michael E. DeBakey VA Medical Center|VA Boston Healthcare System
2024-05-01 Phase 2
NCT06173596 COMPLETED
Healthy
Alexion Pharmaceuticals, Inc.
2024-01-10 PHASE1
NCT05840952 COMPLETED
COVID-19
Aligos Therapeutics
2023-07-04 PHASE1
NCT06357520 Recruiting
Healthy Participants
AstraZeneca
2024-04-16 Phase 1
NCT06348888 Recruiting
Advanced Non-small Cell Lung Cancer|EGFR Mutation|HER2 Mutation|Healthy Volunteers
Bayer
2024-04-10 Phase 1
NCT02875223 TERMINATED
Lymphoma, Non-Hodgkin; Neoplasms
Celgene
2016-08-31 PHASE1
NCT06362642 Recruiting
Healthy Volunteers
PMV Pharmaceuticals Inc
2024-03-28 Phase 1
NCT05049525 TERMINATED
Crohn's Disease; Inflammatory Bowel Diseases
Montreal Heart Institute
2022-02-22 PHASE2
NCT05667662 TERMINATED
ABPA
Pulmatrix Inc.
2023-02-01 PHASE2
NCT05609253 ACTIVE_NOT_RECRUITING
Barrett Oesophagitis With Dysplasia
University of Kansas Medical Center
2022-09-14 EARLY_PHASE1
NCT06162169 COMPLETED
Healthy Subjects
Allist Pharmaceuticals, Inc.
2023-11-25 PHASE1
NCT06105255 COMPLETED
Healthy Male
InventisBio Co., Ltd
2023-05-24 PHASE1
NCT06024915 COMPLETED
Myelofibrosis
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2023-09-21 PHASE1
NCT06688045 COMPLETED
Healthy
Merck Sharp & Dohme LLC
2023-10-30 PHASE1
NCT06165822 UNKNOWN
Advanced Malignant Neoplasm
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2023-12 PHASE1
NCT05902728 COMPLETED
NSCLC
Shanghai Henlius Biotech
2023-07-04 PHASE1
NCT04886323 COMPLETED
Malassezia Folliculitis
The Second Hospital of Anhui Medical University
2022-08-03
NCT06106334 COMPLETED
Obesity; Healthy Volunteers
Shionogi
2023-11-15 PHASE1
NCT05954624 COMPLETED
Drug Drug Interaction
Guangdong Raynovent Biotech Co., Ltd
2023-07-10 PHASE1
NCT05965219 COMPLETED
Healthy Volunteers
Cerevel Therapeutics, LLC
2023-08-15 PHASE1
NCT06041438 COMPLETED
Healthy
Boehringer Ingelheim
2023-09-29 PHASE1
NCT05965583 COMPLETED
Healthy
Boehringer Ingelheim
2023-08-02 PHASE1
NCT05691699 COMPLETED
Healthy Volunteer
AbbVie
2023-01-03 PHASE1
NCT05932303 COMPLETED
Healthy Participants
Bristol-Myers Squibb
2023-07-12 PHASE1
NCT05699993 COMPLETED
Healthy Subjects
Innovent Biologics (Suzhou) Co. Ltd.
2023-03-10 PHASE1
NCT05881980 UNKNOWN
Tinea Corporis; Tinea Cruris; Tinea Faciei; Dermatophytoses
Dhaka Medical College
2023-05 PHASE2; PHASE3
NCT05684718 COMPLETED
Bacterial Infections
BioVersys AG
2023-02-01 PHASE1
NCT05949385 COMPLETED
Pharmacokinetics
Nanjing Zenshine Pharmaceuticals
2023-07-02 PHASE1
NCT05994807 COMPLETED
Healthy Volunteers
DICE Therapeutics, Inc., a wholly owned subsidiary of Eli Lilly and Company
2023-08-08 PHASE1
NCT05789342 COMPLETED
Healthy Volunteers
Jiangxi Qingfeng Pharmaceutical Co. Ltd.
2023-02-15 PHASE1
NCT06089733 COMPLETED
Healthy Subjects
Abbisko Therapeutics Co, Ltd
2023-04-11 PHASE1
NCT03513211 COMPLETED
Prostate Cancer
St Vincent's Hospital, Sydney
2018-08-23 PHASE1; PHASE2
NCT05860933 COMPLETED
Healthy
Eli Lilly and Company
2023-05-08 PHASE1
NCT05822440 COMPLETED
Healthy
Pfizer
2023-04-13 PHASE1
NCT05129033 UNKNOWN
Allergic Bronchopulmonary Aspergillosis
Shanghai Zhongshan Hospital
2021-11-15
NCT05833139 COMPLETED
Healthy
Boehringer Ingelheim
2023-04-14 PHASE1
NCT06087055 COMPLETED
Healthy Participant
Fujian Akeylink Biotechnology Co., Ltd.
2023-05-12 PHASE1
NCT05745701 COMPLETED
Healthy
Pfizer
2023-02-22 PHASE1
NCT05538312 COMPLETED
Healthy
Pfizer
2023-02-23 PHASE1
NCT05573724 COMPLETED
Advanced Solid Malignancies
AstraZeneca
2022-11-07 PHASE1
NCT05586568 UNKNOWN
Healthy Subjects
Xuanzhu Biopharmaceutical Co., Ltd.
2022-11-15 PHASE1
NCT04537715 COMPLETED
All Malignancies; Advanced Malignancies; Hematologic Malignancy; Solid Tumor; Follicular Lymphoma (FL); Non-Hodgkin Lymphoma (NHL); Diffuse Large B-Cell Lymphoma (DLBCL); Epithelioid Sarcoma (ES); Synovial Sarcoma; Renal Medullary Carcinoma; Mesothelioma; Rhabdoid Tumor
Epizyme, Inc.
2020-04-23 PHASE1
NCT05348096 UNKNOWN
Chronic Graft-versus-host-disease
Hospital Universitario Dr. Jose E. Gonzalez
2022-04-01 PHASE2
NCT05685719 COMPLETED
COVID-19 Pneumonia
Zhejiang ACEA Pharmaceutical Co. Ltd.
2023-01-04 PHASE1
NCT05518734 COMPLETED
Pain
Vertex Pharmaceuticals Incorporated
2022-09-17 PHASE1
NCT05635305 COMPLETED
Healthy Volunteers
Global Antibiotics Research and Development Partnership
2022-11-09 PHASE1
NCT05720767 COMPLETED
Relapsed or Refractory Lymphoma
Hutchmed
2022-11-04 PHASE1
NCT05665647 COMPLETED
Healthy Volunteers
Jiangsu Simcere Pharmaceutical Co., Ltd.
2022-12-29 PHASE1
NCT05048615 COMPLETED
AML
Hospital Universitario Dr. Jose E. Gonzalez
2021-07-26 PHASE2
NCT05551897 COMPLETED
Healthy Subjects
AstraZeneca
2022-10-04 PHASE1
NCT05594602 COMPLETED
COVID-19
Enanta Pharmaceuticals, Inc
2022-10-06 PHASE1
NCT07542847 COMPLETED
Healthy Volunteers
Otsuka Pharmaceutical Development & Commercialization, Inc.
2022-09-19 PHASE1
NCT05304533 COMPLETED
Healthy Participants
Bristol-Myers Squibb
2022-04-21 PHASE1
NCT05389722 COMPLETED
Healthy Volunteers
Bristol-Myers Squibb
2022-06-09 PHASE1
NCT05549531 COMPLETED
Healthy
Idorsia Pharmaceuticals Ltd.
2022-10-01 PHASE1
NCT04586920 TERMINATED
Healthy
Eli Lilly and Company
2020-10-20 PHASE1
NCT05486949 COMPLETED
Healthy Subjects
Dizal Pharmaceuticals
2022-07-27 PHASE1
NCT05862714 COMPLETED
Tinea Versicolor
Combined Military Hospital Abbottabad
2022-03-01 PHASE1
NCT04564612 COMPLETED
Healthy Volunteers
Biogen
2020-09-28 PHASE1
NCT04809649 WITHDRAWN
Coccidioidomycosis; Valley Fever
George R Thompson
2021-05-15 PHASE2
NCT05578950 COMPLETED
Onychomycosis
Combined Military Hospital Abbottabad
2022-03-01 PHASE1
NCT05236543 COMPLETED
Healthy Volunteers
AstraZeneca
2022-02-18 PHASE1
NCT05602597 COMPLETED
Relapsed or Refractory Lymphoma
Hutchmed
2022-06-01 PHASE1
NCT05631678 COMPLETED
Locally Advanced or Metastatic NSCLC
Jiangsu Aosaikang Pharmaceutical Co., Ltd.
2022-06-06 PHASE1
NCT05437094 COMPLETED
Clinical Pharmacology; Pharmacokinetics; Cardiovascular Diseases; Heart Failure
Cardurion Pharmaceuticals, Inc.
2022-06-27 PHASE1
NCT05076955 UNKNOWN
Diabetic Foot Ulcer
University of Mississippi Medical Center
2021-03-31 EARLY_PHASE1
NCT05404724 COMPLETED
Rheumatoid Arthritis
Jiangsu HengRui Medicine Co., Ltd.
2022-06-25 PHASE1
NCT05162222 COMPLETED
Healthy Participants
Bristol-Myers Squibb
2021-12-15 PHASE1
NCT05203822 COMPLETED
Healthy
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany
2022-01-21 PHASE1
NCT05797753 COMPLETED
Amyotrophic Lateral Sclerosis; Healthy Volunteer
Sanofi
2022-02-18 PHASE1
NCT04959266 TERMINATED
Advanced Solid Tumours
AstraZeneca
2021-06-28 PHASE1
NCT05418582 COMPLETED
Healthy Subjects
Dizal Pharmaceuticals
2022-01-25 PHASE1
NCT04035187 COMPLETED
Fungal Infection
University of Maryland, Baltimore
2020-02-10 PHASE4
NCT05084651 COMPLETED
Malaria
Novartis Pharmaceuticals
2021-11-18 PHASE1
NCT05255276 COMPLETED
Healthy Adults
Mirati Therapeutics Inc.
2022-02-02 PHASE1
NCT04956627 COMPLETED
Healthy Participants
Bristol-Myers Squibb
2021-07-28 PHASE1
NCT07001501 COMPLETED
Healthy
Henan Genuine Biotech Co., Ltd.
2022-02-21 PHASE1
NCT04908800 COMPLETED
Healthy
Kyorin Pharmaceutical Co.,Ltd
2021-05-27 PHASE1
NCT05063318 COMPLETED
Advanced Solid Tumors
PharmaMar
2020-10-07 PHASE1
NCT04840888 COMPLETED
Healthy
Eli Lilly and Company
2021-04-26 PHASE1
NCT05205447 TERMINATED
Healthy
Eli Lilly and Company
2022-01-05 PHASE1
NCT05272683 COMPLETED
Healthy
Lakefront Biotherapeutics NV
2022-02-28 PHASE1
NCT04880980 COMPLETED
Dermatophyte Infection; Terbinafine Adverse Reaction; Itraconazole Adverse Reaction
Pak Emirates Military Hospital
2021-03-15 PHASE3
NCT05057949 COMPLETED
Healthy Volunteers
Sunshine Lake Pharma Co., Ltd.
2021-11-24 PHASE1
NCT05928988 COMPLETED
Healthy
Jiangsu HengRui Medicine Co., Ltd.
2022-01-04 PHASE1
NCT05359055 COMPLETED
Drug Drug Interaction
Shanghai Pharmaceuticals Holding Co., Ltd
2021-12-13 PHASE1; PHASE2
NCT06246695 COMPLETED
Healthy Volunteers
Suzhou Zelgen Biopharmaceuticals Co.,Ltd
2021-10-27 PHASE1
NCT05316857 COMPLETED
Healthy Person
Beijing InnoCare Pharma Tech Co., Ltd.
2021-12-16 PHASE1
NCT05567484 COMPLETED
Onychomychosis
Combined Military Hospital Abbottabad
2021-05-01 PHASE1
NCT03827278 UNKNOWN
Talaromyces in Human Immunodeficiency Virus Negative; To Compare Voriconazole and Amphotericin Sequential Itraconazole Therapy; To Dynamically Monitor the Anti-Interferon-γ Autoantibodies
Guangxi Medical University
2018-12-30
NCT05154136 COMPLETED
Healthy Participants
Arcus Biosciences, Inc.
2021-10-20 PHASE1
NCT05357820 COMPLETED
Solid Tumor
Nuvation Bio Inc.
2021-07-19 PHASE1
NCT03340220 COMPLETED
Healthy Volunteers
Xenon Pharmaceuticals Inc.
2017-11-13 PHASE1
NCT05064449 COMPLETED
Healthy Volunteers
Takeda
2021-10-14 PHASE1
NCT05069870 UNKNOWN
Healthy Subjects
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.
2021-06-07 PHASE1
NCT04962022 COMPLETED
Healthy Participant
Pfizer
2021-07-20 PHASE1
NCT02699723 WITHDRAWN
Skin Basal Cell Carcinoma
Jean Yuh Tang
2020-12 EARLY_PHASE1
NCT04154800 COMPLETED
Health Participants
Bristol-Myers Squibb
2019-12-06 PHASE1
NCT04942652 COMPLETED
Achlorhydria
Seoul National University Hospital
2021-07-13 PHASE1
NCT04481100 UNKNOWN
Esophageal Neoplasm; Esophageal Diseases; Esophageal Squamous Cell Carcinoma
Hangzhou Cancer Hospital
2020-10-01 PHASE2
NCT04619251 COMPLETED
Healthy
Boehringer Ingelheim
2020-11-13 PHASE1
NCT03920527 COMPLETED
Chronic Pulmonary Aspergillosis
Post Graduate Institute of Medical Education and Research, Chandigarh
2019-07-01 PHASE3
NCT04981704 COMPLETED
Healthy
Spectrum Pharmaceuticals, Inc
2021-04-08 PHASE1
NCT04604795 COMPLETED
Celiac Disease; Coeliac Disease
GlaxoSmithKline
2020-11-04 PHASE1
NCT04783753 COMPLETED
Hepatitis B
Enanta Pharmaceuticals, Inc
2020-11-05 PHASE1
NCT04845646 COMPLETED
Healthy; NAFLD
Gannex Pharma Co., Ltd.
2021-03-16 PHASE1
NCT03086226 COMPLETED
Mycetoma
Drugs for Neglected Diseases
2017-05-09 PHASE2
NCT04808648 UNKNOWN
Healthy Male Volunteers
Nanjing Sanhome Pharmaceutical, Co., Ltd.
2021-04-06 PHASE1
NCT04464577 WITHDRAWN
Healthy Participants
Bristol-Myers Squibb
2021-04-01 PHASE1
NCT04268394 COMPLETED
Healthy Volunteer
Celgene
2020-03-13 PHASE1
NCT03572049 COMPLETED
Invasive Fungal Infections
University of Alabama at Birmingham
2018-09-17 PHASE2; PHASE3
NCT04843449 COMPLETED
Healthy
Ascletis Pharmaceuticals Co., Ltd.
2021-04-04 PHASE1
NCT04714073 COMPLETED
Healthy
Boehringer Ingelheim
2021-02-11 PHASE1
NCT04739774 COMPLETED
Chronic Obstructive Pulmonary Disease
Chiesi Farmaceutici S.p.A.
2021-02-22 PHASE1
NCT04716894 COMPLETED
Healthy
Boehringer Ingelheim
2021-02-01 PHASE1
NCT04743414 COMPLETED
Healthy Volunteers
Concert Pharmaceuticals
2021-03-02 PHASE1
NCT04712396 COMPLETED
Healthy Volunteers (Intended Indication: Metastatic Patients With Triple Negative or HR+ Breast Cancer, or Hormone Sensitive Prostate Cancer)
AstraZeneca
2021-02-01 PHASE1
NCT04584515 COMPLETED
Solid Tumor
Impact Therapeutics, Inc.
2020-11-02 PHASE1
NCT04290390 COMPLETED
Women; Contraception
TherapeuticsMD
2020-02-12 PHASE1
NCT04410094 COMPLETED
Healthy
Janssen Research & Development, LLC
2020-09-14 PHASE1
NCT03972748 UNKNOWN
Basal Cell Carcinoma; Hedgehog Pathway
Hospital de Clinicas de Porto Alegre
2018-01-05
NCT04606537 COMPLETED
Healthy; Drug Drug Interaction
KBP Biosciences
2020-10-24 PHASE1
NCT04577378 UNKNOWN
Covid19
Kafrelsheikh University
2020-10-20 PHASE2
NCT04557163 COMPLETED
Healthy Subjects
Taisho Pharmaceutical Co., Ltd.
2020-10-13 PHASE1
NCT05134337 COMPLETED
Healthy Volunteers
Loxo Oncology, Inc.
2020-02-12 PHASE1
NCT04557397 COMPLETED
Drug Drug Interaction
Hutchison Medipharma Limited
2020-09-02 PHASE1
NCT04627129 COMPLETED
Healthy Adult Subjects
Jiangsu HengRui Medicine Co., Ltd.
2020-06-01 PHASE1
NCT04312282 TERMINATED
Advanced Solid Tumors
Odonate Therapeutics, Inc.
2020-03-06 PHASE1
NCT04372407 COMPLETED
Healthy
Hutchison Medipharma Limited
2020-07-09 PHASE1
NCT04411030 COMPLETED
Healthy Volunteer
Astex Pharmaceuticals, Inc.
2020-05-20 PHASE1
NCT04455100 COMPLETED
Health, Subjective
Jiangsu HengRui Medicine Co., Ltd.
2020-07-17 PHASE1
NCT00585195 COMPLETED
Non-Small Cell Lung Cancer ALK-positive; Non-Small Cell Lung Cancer c-Met Dependent; Non-Small Cell Lung Cancer ROS Marker Positive; Systemic Anaplastic Large-Cell Lymphoma; Advanced Malignancies Except Leukemia
Pfizer
2006-04-19 PHASE1
NCT04423601 COMPLETED
Healthy Subjects
Jiangsu HengRui Medicine Co., Ltd.
2020-06-10 PHASE1
NCT04405323 COMPLETED
Healthy
H. Lundbeck A/S
2020-05-20 PHASE1
NCT04135833 COMPLETED
NSCLC
Beta Pharma, Inc.
2019-12-12 PHASE1
NCT03960606 TERMINATED
Allergic Bronchopulmonary Aspergillosis
Pulmatrix Inc.
2019-07-31 PHASE2
NCT06090123 COMPLETED
Erectile Dysfunction
Vigonvita Life Sciences
2020-01-01 PHASE1
NCT04709081 COMPLETED
Healthy
Alexion Pharmaceuticals, Inc.
2019-12-22 PHASE1
NCT03923010 TERMINATED
Mycoses
Janssen Research & Development, LLC
2019-08-06 PHASE4
NCT04208373 COMPLETED
Healthy
Janssen Research & Development, LLC
2019-12-20 PHASE1
NCT04166669 COMPLETED
Fungal Infection
Basilea Pharmaceutica
2019-11-12 PHASE1
NCT04171739 COMPLETED
Healthy
F2G Ltd
2019-11-18 PHASE1
NCT04014361 TERMINATED
Healthy
Eli Lilly and Company
2019-08-09 PHASE1
NCT04142762 COMPLETED
Chronic Hepatitis B
Assembly Biosciences
2019-10-18 PHASE1
NCT04121910 COMPLETED
Solid Tumour
AstraZeneca
2019-11-07 PHASE1
NCT04090047 COMPLETED
Heathy Participants
Pfizer
2019-09-24 PHASE1
NCT05568082 COMPLETED
Healthy Participants
Amgen
2019-12-03 PHASE1
NCT03664115 UNKNOWN
Lung Cancer
Ain Shams University
2018-07-02 PHASE2
NCT04138836 COMPLETED
Healthy Participants
Bridge Biotherapeutics, Inc.
2019-09-17 PHASE1
NCT03994211 COMPLETED
Solid Tumor
BeiGene
2019-05-29 PHASE1
NCT04479891 COMPLETED
Healthy Subjects
Jiangsu HengRui Medicine Co., Ltd.
2019-09-18 PHASE1
NCT03945539 COMPLETED
Healthy
Janssen Sciences Ireland UC
2019-05-15 PHASE1
NCT03631602 UNKNOWN
IFD Post-HSCT
Fujian Medical University
2017-10-01 PHASE2; PHASE3
NCT04011241 COMPLETED
Healthy
Boehringer Ingelheim
2019-07-24 PHASE1
NCT02749513 UNKNOWN
Esophageal Cancer
Dallas VA Medical Center
2016-01 EARLY_PHASE1
NCT03081702 COMPLETED
Platinum-resistant Epithelial Ovarian Cancer
University Health Network, Toronto
2017-07-25 PHASE1; PHASE2
NCT04008186 COMPLETED
Healthy Adult Subjects
Biogen
2019-06-14 PHASE1
NCT03928327 COMPLETED
Healthy Volunteers
Millennium Pharmaceuticals, Inc.
2019-05-02 PHASE1
NCT03991312 COMPLETED
Healthy Volunteers
Agios Pharmaceuticals, Inc.
2019-06-20 PHASE1
NCT03950960 COMPLETED
Healthy Participants
Bristol-Myers Squibb
2019-05-02 PHASE1
NCT03512548 COMPLETED
Healthy
Corcept Therapeutics
2018-04-10 PHASE1
NCT03890887 COMPLETED
Healthy
Boehringer Ingelheim
2019-04-12 PHASE1
NCT03892499 COMPLETED
Healthy
Cyclerion Therapeutics
2019-05-03 PHASE1
NCT03843151 COMPLETED
Healthy
Boehringer Ingelheim
2019-03-19 PHASE1
NCT02285283 TERMINATED
Chronic Rhinosinusitis
The University of Texas Health Science Center, Houston
2014-11 PHASE2; PHASE3
NCT03103646 COMPLETED
Cytochrome P450 Interaction
H. Lundbeck A/S
2017-03-28 PHASE1
NCT03821493 COMPLETED
Healthy Participants
Pfizer
2019-02-21 PHASE1
NCT03843060 COMPLETED
Heart Failure With Preserved Ejection Fraction (HFpEF)
AstraZeneca
2019-02-22 PHASE1
NCT03782662 COMPLETED
Respiratory Syncytial Virus Infections
Pfizer
2018-11-07 PHASE1
NCT03774576 COMPLETED
Healthy Volunteers
Hoffmann-La Roche
2018-12-17 PHASE1
NCT03782987 COMPLETED
Healthy
Boehringer Ingelheim
2019-01-10 PHASE1
NCT03789890 COMPLETED
Drug Interactions
Bayer
2019-01-08 PHASE1
NCT02354261 COMPLETED
Basal Cell Carcinoma in Basal Cell Nevus Syndrome
HedgePath Pharmaceuticals, Inc.
2015-08-07 PHASE2
NCT03792139 COMPLETED
Healthy
Eli Lilly and Company
2019-01-08 PHASE1
NCT03530995 COMPLETED
Drug-drug Interaction; Autoimmune Diseases; Fibrotic Disease
Kadmon Corporation, LLC
2018-04-09 PHASE1
NCT02120677 COMPLETED
Basal Cell Carcinoma
Johns Hopkins University
2014-05 EARLY_PHASE1
NCT03755778 COMPLETED
RSV Infection
Enanta Pharmaceuticals, Inc
2018-11-29 PHASE1
NCT03471455 UNKNOWN
Tinea
Post Graduate Institute of Medical Education and Research, Chandigarh
2018-04 PHASE2
NCT03723395 COMPLETED
Drug-drug Interaction
Seagen Inc.
2018-09-17 PHASE1
NCT03722173 COMPLETED
Healthy
Boehringer Ingelheim
2018-11-13 PHASE1
NCT03579719 COMPLETED
Healthy Volunteers
Hoffmann-La Roche
2018-07-10 PHASE1
NCT06421714 COMPLETED
Healthy Volunteers
Genzyme, a Sanofi Company
2018-08-16 PHASE1
NCT03614455 COMPLETED
Pharmacokinetics
Daiichi Sankyo
2018-07-13 EARLY_PHASE1
NCT02770378 COMPLETED
Glioblastoma
University of Ulm
2016-11 PHASE1; PHASE2
NCT03383692 COMPLETED
Neoplasm Metastasis
Daiichi Sankyo Co., Ltd.
2018-01-12 PHASE1
NCT02608034 COMPLETED
Metastatic Melanoma, BRAF V600 Mutation Positive
Genentech, Inc.
2016-05-26 PHASE1
NCT03624959 COMPLETED
Healthy Volunteer
Celgene
2018-06-20 PHASE1
NCT03535662 COMPLETED
Pharmacokinetic Study in Healthy Male Volunteers
Nerre Therapeutics Ltd.
2018-06-08 PHASE1
NCT05338489 COMPLETED
Healthy
Eli Lilly and Company
2018-05-11 PHASE1
NCT03403439 COMPLETED
Healthy
Boehringer Ingelheim
2018-05-03 PHASE1
NCT03555617 COMPLETED
Inflammatory Bowel Disease
Theravance Biopharma
2018-06-13 PHASE1
NCT03499106 COMPLETED
Healthy
Cyclerion Therapeutics
2018-04-12 PHASE1
NCT02357836 COMPLETED
Non-small Cell Lung Cancer
University of Texas Southwestern Medical Center
2015-06 EARLY_PHASE1
NCT03479411 COMPLETED
Asthma
Pulmatrix Inc.
2018-02-09 PHASE1
NCT02824042 COMPLETED
Medical Oncology
Bayer
2016-09-07 PHASE1
NCT04110834 COMPLETED
Tinea Versicolor
Sara Botros
2018-02-15 PHASE2
NCT03515382 COMPLETED
Healthy
Lakefront Biotherapeutics NV
2018-03-16 PHASE1
NCT03498170 COMPLETED
Interaction
Mereo BioPharma
2018-03-19 PHASE1
NCT02895529 TERMINATED
Hematologic Neoplasms
Xian-Janssen Pharmaceutical Ltd.
2016-11-30 PHASE4
NCT03432793 COMPLETED
Drug Drug Interaction (DDI)
Theravance Biopharma
2018-02-28 PHASE1
NCT03398421 COMPLETED
Pulmonary Disease, Chronic Obstructive
GlaxoSmithKline
2018-01-17 PHASE1
NCT02253420 COMPLETED
Medical Oncology
Bayer
2014-10-08 PHASE1
NCT03340662 COMPLETED
Healthy Volunteer
Celgene
2017-11-09 PHASE1
NCT02130661 WITHDRAWN
Alzheimer's Disease
GlaxoSmithKline
2017-10 PHASE1
NCT03346837 COMPLETED
Malignancies Multiple
Bristol-Myers Squibb
2017-11-22 PHASE1
NCT03077607 COMPLETED
Advanced Solid Tumors
Pfizer
2016-11-07 PHASE1
NCT03259542 COMPLETED
Drug Interaction Potentiation; Healthy
Corcept Therapeutics
2017-08-09 PHASE1
NCT04080596 COMPLETED
Drug Interaction
Hua Medicine Limited
2017-10-13 PHASE1
NCT03264079 COMPLETED
Healthy Volunteers
Biogen
2017-10-16 PHASE1
NCT03301181 COMPLETED
Healthy Volunteers: Asian, Non-Asian
BeiGene
2017-09-18 PHASE1
NCT02735356 COMPLETED
Skin Basal Cell Carcinoma
Jean Yuh Tang
2016-05-05 EARLY_PHASE1
NCT03121664 COMPLETED
Healthy
Pfizer
2017-04-07 PHASE1
NCT03119077 TERMINATED
Polycystic Ovary Syndrome
Bayer
2017-04-27 PHASE1
NCT03222310 COMPLETED
Healthy Volunteers
Hoffmann-La Roche
2017-07-18 PHASE1
NCT03135106 COMPLETED
Healthy
Janssen Research & Development, LLC
2017-04-14 PHASE1
NCT03209648 COMPLETED
Healthy Participants
Debiopharm International SA
2017-06-14 PHASE1
NCT03213145 COMPLETED
NASH - Nonalcoholic Steatohepatitis
Enanta Pharmaceuticals, Inc
2017-07-11 PHASE1
NCT03173170 COMPLETED
Healthy Participants
Takeda
2017-05-31 PHASE1
NCT02989389 COMPLETED
Healthy
Eli Lilly and Company
2016-12-12 PHASE1
NCT03161405 COMPLETED
Healthy Participants
Millennium Pharmaceuticals, Inc.
2017-06-05 PHASE1
NCT02440009 COMPLETED
Allergic Bronchopulmonary Aspergillosis
Post Graduate Institute of Medical Education and Research, Chandigarh
2014-05 PHASE2; PHASE3
NCT03174041 COMPLETED
Healthy Participants
Genentech, Inc.
2017-04-18 PHASE1
NCT02122770 COMPLETED
Advanced Solid Tumors
Millennium Pharmaceuticals, Inc.
2014-04-01 PHASE1
NCT03138785 UNKNOWN
Treatment
Farabi Eye Hospital
2015-01-01
NCT03116893 COMPLETED
Healthy
Boehringer Ingelheim
2017-04-19 PHASE1
NCT01787331 COMPLETED
Prostate Adenocarcinoma; Recurrent Prostate Carcinoma; Stage I Prostate Adenocarcinoma AJCC v7; Stage II Prostate Adenocarcinoma AJCC v7; Stage III Prostate Adenocarcinoma AJCC v7
University of California, San Francisco
2013-10-29 PHASE2
NCT02817100 COMPLETED
Clinical Trials, Phase I as Topic
Bayer
2016-07-22 PHASE1
NCT03048110 COMPLETED
Biological Availability
Bayer
2017-02-15 PHASE1
NCT02838264 COMPLETED
Healthy
Pfizer
2016-08-16 PHASE1
NCT02975037 COMPLETED
Healthy
Seoul National University Hospital
2017-02-06 PHASE1
NCT02836171 COMPLETED
Neoplasms
Jiangsu HengRui Medicine Co., Ltd.
2016-07 PHASE1
NCT02706535 COMPLETED
Drug Interactions; Neoplasms
GlaxoSmithKline
2016-05-05 PHASE1
NCT02828241 COMPLETED
Rosacea
Dr. Reddy's Laboratories Limited
2016-07 PHASE2
NCT02755857 COMPLETED
Neutropenia
Mayne Pharma International Pty Ltd
2016-07 PHASE2
NCT02567773 COMPLETED
Cachexia
GlaxoSmithKline
2015-09 PHASE1
NCT02883114 COMPLETED
Healthy
Pfizer
2016-09 PHASE1
NCT02831972 COMPLETED
Healthy
Agios Pharmaceuticals, Inc.
2016-06 PHASE1
NCT02820935 COMPLETED
Pharmacokinetics
Celgene Corporation
2016-07 PHASE1
NCT02633709 COMPLETED
Spinal Muscular Atrophy
Hoffmann-La Roche
2016-01-07 PHASE1
NCT02809768 COMPLETED
Healthy Participants
Eisai Inc.
2016-04 PHASE1
NCT02807909 COMPLETED
Thrombosis
Bristol-Myers Squibb
2016-07 PHASE1
NCT02729467 COMPLETED
Healthy
Janssen Research & Development, LLC
2016-03 PHASE1
NCT02790671 COMPLETED
Pharmacokinetics
Daiichi Sankyo
2016-05 PHASE1
NCT02420782 COMPLETED
Healthy Volunteers
Astellas Pharma Europe B.V.
2015-05 PHASE1
NCT02653872 COMPLETED
Healthy Subjects
AstraZeneca
2016-01-22 PHASE1
NCT02698267 COMPLETED
Neuropathic Pain
Biogen
2016-02 PHASE1
NCT06004947 COMPLETED
Anti-neutrophil Cytoplasmic Antibody-associated Vasculitis
Amgen
2016-01-14 PHASE1
NCT02457351 COMPLETED
Medical Oncology
Bayer
2015-07 PHASE1
NCT02323334 COMPLETED
Healthy Volunteers; Alzheimer Disease
Eli Lilly and Company
2014-12 PHASE1
NCT02513446 COMPLETED
Healthy
Boehringer Ingelheim
2015-09-29 PHASE1
NCT01576315 COMPLETED
Cystic Fibrosis; Aspergillus Infections
Rennes University Hospital
2014-06 PHASE2
NCT01974687 COMPLETED
Chronic Hepatitis C
Merck Sharp & Dohme LLC
2013-10-31 PHASE1; PHASE2
NCT02341638 COMPLETED
Thrombosis
Bristol-Myers Squibb
2014-09 PHASE1
NCT02456129 COMPLETED
Clinical Trial, Phase I
Bayer
2015-07 PHASE1
NCT02475746 WITHDRAWN
Healthy
Pfizer
2015-07 PHASE1
NCT02401295 COMPLETED
Relapsed Multiple Myeloma
University of Iowa
2015-05 PHASE1
NCT02402595 COMPLETED
Healthy
Otsuka Pharmaceutical Development & Commercialization, Inc.
2015-03-01 PHASE1
NCT02470832 COMPLETED
Healthy Patient Study
Hoffmann-La Roche
2015-05 PHASE1
NCT02440841 COMPLETED
Nocturia
Vantia Ltd
2015-05 PHASE1
NCT02455856 COMPLETED
Healthy
Janssen Cilag N.V./S.A.
2015-05-18 PHASE1
NCT02054793 WITHDRAWN
Prostate Cancer; Castration-resistant Prostate Cancer
Emmanuel Antonarakis, MD
2014-06 PHASE1; PHASE2
NCT02365571 COMPLETED
Healthy Participants
Eli Lilly and Company
2015-02 PHASE1
NCT02157883 COMPLETED
Advanced Non Small Cell Lung Cancer; Advanced (Inoperable) Non Small Cell Lung Cancer
AstraZeneca
2014-11-06 PHASE1
NCT02300259 COMPLETED
Healthy Volunteers
Eli Lilly and Company
2014-11 PHASE1
NCT02328443 COMPLETED
Healthy
Seoul National University Hospital
2014-01 PHASE1
NCT02370615 COMPLETED
Japanese Healthy Adult Males
Takeda
2015-02 PHASE1
NCT02341482 COMPLETED
Healthy
Biogen
2015-02-05 PHASE1
NCT02259010 COMPLETED
Advanced Solid Tumors; Relapsed/Refractory Lymphoma
Millennium Pharmaceuticals, Inc.
2014-10-22 PHASE1
NCT02342717 COMPLETED
Healthy
Boehringer Ingelheim
2015-01 PHASE1
NCT02199431 COMPLETED
Healthy
H. Lundbeck A/S
2014-07 PHASE1
NCT02248259 COMPLETED
Healthy
Boehringer Ingelheim
2014-10-08 PHASE1
NCT02230033 COMPLETED
Healthy
Aragon Pharmaceuticals, Inc.
2014-09 PHASE1
NCT02272764 COMPLETED
Pharmacokinetics
Alkermes, Inc.
2014-10 PHASE1
NCT02155504 COMPLETED
Healthy Volunteers; Pharmacokinetics of ASP3700
Astellas Pharma Europe B.V.
2014-05 PHASE1
NCT02319148 COMPLETED
Healthy Volunteers
Pfizer
2014-07 PHASE1
NCT02197884 COMPLETED
Healthy
Janssen Research & Development, LLC
2014-07 PHASE1
NCT02045849 COMPLETED
Infections, Bacterial
GlaxoSmithKline
2014-01-28 PHASE1
NCT02118909 COMPLETED
Healthy Volunteers; Non-smokers
Helsinn Healthcare SA
2014-05 PHASE1
NCT02131298 COMPLETED
Healthy
Pfizer
2014-05 PHASE1
NCT02093728 COMPLETED
Solid Tumours
AstraZeneca
2014-04 PHASE1
NCT02175407 COMPLETED
Pharmacokinetics; DDI (Drug-Drug Interaction); Healthy Subjects
Astellas Pharma Europe B.V.
2014-04 PHASE1
NCT02100553 COMPLETED
Healthy
Pfizer
2014-04 PHASE1
NCT02122692 COMPLETED
Healthy Volunteers
H. Lundbeck A/S
2014-03 PHASE1
NCT01772563 COMPLETED
Neoplasms
Boehringer Ingelheim
2013-02-04 PHASE1
NCT04901923 COMPLETED
Healthy Participants
Acerta Pharma BV
2014-03-15 PHASE1
NCT02044393 COMPLETED
Healthy
Boehringer Ingelheim
2014-01 PHASE1
NCT02085967 COMPLETED
Healthy Subjects
Eisai Inc.
2014-02 PHASE1
NCT02055703 COMPLETED
Healthy Subjects
Eisai Inc.
2014-01 PHASE1
NCT01752023 TERMINATED
Non-small Cell Lung Cancer Metastatic
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
2013-03 PHASE2
NCT01900028 COMPLETED
Solid Tumours
AstraZeneca
2013-10 PHASE1
NCT01344681 COMPLETED
Febrile Neutropenia; Hematological Diseases
Yonsei University
2011-06 PHASE2
NCT02065739 COMPLETED
Healthy
Janssen Pharmaceutica N.V., Belgium
2014-01 PHASE1
NCT02010970 COMPLETED
Healthy Volunteers; Pharmacologic Action
AstraZeneca
2013-12 PHASE1
NCT00588016 COMPLETED
Sinusitis
Mayo Clinic
2007-04 PHASE1
NCT01967979 COMPLETED
Healthy Volunteer
Hoffmann-La Roche
2013-10 PHASE1
NCT01929876 COMPLETED
Healthy Participants
Genentech, Inc.
2013-07 PHASE1
NCT01768663 COMPLETED
Cystic Fibrosis
Vertex Pharmaceuticals Incorporated
2013-01 PHASE1
NCT01814709 COMPLETED
Healthy Volunteer
Genentech, Inc.
2013-04 PHASE1
NCT01772290 COMPLETED
Healthy Volunteer
Genentech, Inc.
2013-02 PHASE1
NCT01795937 COMPLETED
Healthy
Boehringer Ingelheim
2013-02 PHASE1
NCT01321827 COMPLETED
Allergic Bronchopulmonary Aspergillosis
Post Graduate Institute of Medical Education and Research, Chandigarh
2011-04 PHASE2; PHASE3
NCT00769600 TERMINATED
Recurrent Non Small Cell Lung Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
2008-11 PHASE2
NCT01568411 COMPLETED
Healthy
Glycyx Therapeutics
2012-04 PHASE1
NCT00798135 COMPLETED
Breast Neoplasms; Neoplasm Metastasis
Indiana University
2008-11
NCT01392430 COMPLETED
HIV Infection
Chiang Mai University
2009-06
NCT01913379 COMPLETED
Healthy Subjects; Pharmacokinetics; Drug-Drug Interaction
Astellas Pharma Europe B.V.
2011-08 PHASE1
NCT01259336 COMPLETED
Chronic Cavitary Pulmonary Aspergillosis
Post Graduate Institute of Medical Education and Research, Chandigarh
2010-07 PHASE4
NCT00887458 COMPLETED
Prostate Cancer
Johns Hopkins University
2009-07 PHASE2
NCT01450683 TERMINATED
Prostate Cancer; Prostatic Neoplasms; Castrate-resistant Prostate Cancer (CRPC); Androgen-insensitive Prostate Cancer; Hormone-refractory Prostate Cancer; Metastatic Disease
Stanford University
2010-09 PHASE2
NCT00673309 COMPLETED
Burns
The University of Texas Medical Branch, Galveston
2000-07 PHASE2; PHASE3
NCT01108094 COMPLETED
Basal Cell Carcinoma (BCC); Skin Cancer
Stanford University
2010-04 PHASE2
NCT01409018 COMPLETED
Pediatric, Cancer
Seoul National University Hospital
2009-06 PHASE1
NCT01282879 TERMINATED
Graft vs Host Disease
Samsung Medical Center
2009-12 PHASE4
NCT01160952 UNKNOWN
Hematological Diseases; Allogeneic Stem Cell Transplantation
Guangzhou General Hospital of Guangzhou Military Command
2009-05 PHASE2
NCT01214941 COMPLETED
Pharmacokinetics; Pharmacodynamics
Turku University Hospital
2010-09 PHASE4
NCT01198236 COMPLETED
Invasive Fungal Infection
Zhejiang University
2008-07 PHASE4
NCT00528190 COMPLETED
Cystic Fibrosis
Ottawa Hospital Research Institute
2007-10 PHASE4
NCT00791219 COMPLETED
Onychomycosis
Halcygen Pharmaceuticals Limited
2008-11 PHASE2
NCT00787917 TERMINATED
Cystic Fibrosis; Allergic Bronchopulmonary Aspergillosis
Novartis Pharmaceuticals
2008-11 PHASE4
NCT00794703 COMPLETED
Fungemia; Fungal Infections
Astellas Pharma Inc
2008-11 PHASE3
NCT00871728 COMPLETED
Onychomycosis, Toe
Janssen Korea, Ltd., Korea
2007-01 PHASE4
NCT00289991 COMPLETED
Antifungal Prophylaxis of Invasive Fungal Infections
Pfizer
2006-03 PHASE3
NCT01823289 COMPLETED
Pulmonary Fungal Infection
Xian-Janssen Pharmaceutical Ltd.
2007-06 PHASE4
NCT00356915 COMPLETED
Onychomycosis
Stiefel, a GSK Company
2006-07 PHASE3
NCT00695071 COMPLETED
Healthy
Stiefel, a GSK Company
2008-06 PHASE1
NCT00336531 COMPLETED
Neuroblastoma; Brain Tumor; Retinoblastoma; Wilms Tumor; Mycoses
Samsung Medical Center
2006-04 PHASE4
NCT00045942 COMPLETED
Acute Myeloid Leukemia; Myelodysplastic Syndromes
Novartis Pharmaceuticals
2002-01-30 PHASE1; PHASE2
NCT00895453 COMPLETED
Vulvovaginal Candidiasis
Medical University of Vienna
2000-05
NCT00079222 COMPLETED
Cancer
Jonsson Comprehensive Cancer Center
2003-11
NCT02264041 COMPLETED
Healthy
Boehringer Ingelheim
2004-01 PHASE1
NCT00003883 COMPLETED
Cancer
Fred Hutchinson Cancer Center
1998-10 PHASE3
NCT00000639 COMPLETED
Meningitis, Cryptococcal; HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00012467 COMPLETED
Meningitis, Cryptococcal; HIV Infections
InterMune
2000-01 PHASE2
NCT00002370 COMPLETED
HIV Infections
Janssen, LP
NCT00002341 COMPLETED
Candidiasis, Oral; HIV Infections
Janssen, LP
NCT00005668 COMPLETED
Aspergillosis; Lung Diseases, Fungal
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT00002159 COMPLETED
HIV Infections; Histoplasmosis; Blastomycosis
Janssen, LP
PHASE3
NCT00000992 COMPLETED
HIV Infections; Histoplasmosis
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00002132 COMPLETED
Candidiasis, Esophageal; HIV Infections
Janssen Pharmaceuticals
NCT00001280 COMPLETED
Mycoses
National Institute of Allergy and Infectious Diseases (NIAID)
1991-01 PHASE2
NCT00002438 COMPLETED
HIV Infections; Histoplasmosis
Janssen, LP
NCT00004811 COMPLETED
Histoplasmosis; Sporotrichosis; Blastomycosis
National Center for Research Resources (NCRR)
1985-03 PHASE1; PHASE2
NCT00000975 COMPLETED
HIV Infections; Histoplasmosis
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT00002133 COMPLETED
Candidiasis, Oral; HIV Infections
Janssen, LP

(data from https://clinicaltrials.gov, updated on 2026-05-08)

Check the Itraconazole product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Compliance for Clinical Use

Mechanism and Biochemical Profile

Itraconazole selectively inhibits cytochrome P450 oxidase-mediated ergosterol synthesis and antagonizes the Hedgehog signaling pathway, thereby disrupting membrane integrity, inducing autophagy, and suppressing cell growth. This targeted biochemical inhibition underlies its broad-spectrum antifungal potency against pathogens such as Aspergillus while providing the mechanistic basis for its investigation in clinical oncology trials for non-small cell lung and esophageal carcinomas.

Appendix RUO and cGMP Quality Standards

Quality Dimension RUO (Research Use Only) cGMP (Current Good Manufacturing Practice)
Clinical Applicability Prohibited in human clinical trials or medical diagnostics. Mandatory for human clinical trials (Phase I–III) and therapies.
Regulatory Status Non-regulated grade; exempt from drug manufacturing laws. Legally enforced by health authorities (e.g., FDA, EMA, NMPA).
Facility Environment Unclassified analytical or research laboratories. Validated Cleanrooms (ISO Class 5–8) with continuous monitoring.
Quality Control Basic purity and activity testing. Rigorous safety release testing (Sterility, Endotoxin, Mycoplasma).
Process Validation Basic equipment calibration; no process validation required. Full qualification (IQ/OQ/PQ) and complete batch records.
Quality Assurance Vendor self-declared without required formal QMS. Mandatory QA/QC unit, Change Control, CAPA, and vendor audits.
Regulatory Impact High risk of IND rejection if used as a critical raw material. Required for IND/NDA filings, supported by Drug Master Files (DMF).

Footnotes

Regulatory Note: Governed by FDA (21 CFR Parts 210/211/312), EMA (EudraLex Vol 4), ICH Guidelines (E6/Q7/Q9/Q10), and compendial standards (USP <71>/<85>/<1043>).

Note: Technical data last updated: Sep 1, 2026.